-
1
-
-
84885854632
-
Correlation of bacterial species and density at baseline to exacerbations requiring antibiotic treatment in a phase 2 trial of ciprofloxacin dry powder for inhalation (ciprofloxacin DPI) compared with placebo in patients with non-cystic fibrosis bronchiectasis
-
Alder J. Hampel B. Reimnitz P. Wilson R. (2012) Correlation of bacterial species and density at baseline to exacerbations requiring antibiotic treatment in a phase 2 trial of ciprofloxacin dry powder for inhalation (ciprofloxacin DPI) compared with placebo in patients with non-cystic fibrosis bronchiectasis. Am J Respir Crit Care Med 185: A6099.
-
(2012)
Am J Respir Crit Care Med
, vol.185
, pp. A6099
-
-
Alder, J.1
Hampel, B.2
Reimnitz, P.3
Wilson, R.4
-
3
-
-
84884583722
-
Aradigm receives U.S. FDA clearance for phase 3 clinical trial of Pulmaquin™ in patients with non-cystic fibrosis bronchiectasis (News Release)
-
Available at:, accessed 24 August 2012
-
Aradigm Corporation (2012) Aradigm receives U.S. FDA clearance for phase 3 clinical trial of Pulmaquin™ in patients with non-cystic fibrosis bronchiectasis (News Release). Available at: http://investor.aradigm.com/releasedetail.cfm?ReleaseID=656453 ( accessed 24 August 2012).
-
(2012)
-
-
-
5
-
-
47049105075
-
Bronchiectasis: introduction, etiology, and clinical features
-
Baydarian M. Walter R. (2008) Bronchiectasis: introduction, etiology, and clinical features. Dis Mon 54: 516–526.
-
(2008)
Dis Mon
, vol.54
, pp. 516-526
-
-
Baydarian, M.1
Walter, R.2
-
6
-
-
84884543178
-
-
Wayne, NJ: Bayer Healthcare Pharmaceuticals, Inc
-
Bayer Healthcare Pharmaceuticals (2009) Cipro tablets, Cipro oral suspension (Package Insert). Wayne, NJ: Bayer Healthcare Pharmaceuticals, Inc.
-
(2009)
Cipro tablets, Cipro oral suspension (Package Insert)
-
-
-
7
-
-
84884567720
-
-
Wayne, NJ: Bayer Healthcare Pharmaceuticals, Inc
-
Bayer Healthcare Pharmaceuticals (2011) Cipro I.V. (Package Insert). Wayne, NJ: Bayer Healthcare Pharmaceuticals, Inc.
-
(2011)
Cipro I.V. (Package Insert)
-
-
-
8
-
-
84884556705
-
Start of global clinical phase III programme RESPIRE for ciprofloxacin dry powder for inhalation (DPI) (News Release)
-
Available at:, accessed 24 August 2012
-
Bayer Healthcare Pharmaceuticals (2012) Start of global clinical phase III programme RESPIRE for ciprofloxacin dry powder for inhalation (DPI) (News Release). Available at: http://press.healthcare.bayer.com/en/press/news-details-page.php/14684/2012-0362 ( accessed 24 August 2012).
-
(2012)
-
-
-
9
-
-
77951888960
-
Inhaled liposomal ciprofloxacin hydrochloride significantly reduces sputum Pseudomonas aeruginosa density in CF and Non–CF Bronchiectasis
-
Bilton D. Bruinenberg P. Otulana B. Morishige R. Blanchard J. De Soyza A. (2009a) Inhaled liposomal ciprofloxacin hydrochloride significantly reduces sputum Pseudomonas aeruginosa density in CF and Non–CF Bronchiectasis. Am J Respir Crit Care Med 179: A3214.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. A3214
-
-
Bilton, D.1
Bruinenberg, P.2
Otulana, B.3
Morishige, R.4
Blanchard, J.5
De Soyza, A.6
-
10
-
-
77956598199
-
Inhaled liposomal ciprofloxacin hydrochloride significantly reduces sputum Pseudomonas aeruginosa density in non-CF bronchiectasis
-
(, Suppl. 53, ):
-
Bilton D. De Soyza A. Haworth C. Bruinenberg P. Otulana B. (2009b) Inhaled liposomal ciprofloxacin hydrochloride significantly reduces sputum Pseudomonas aeruginosa density in non-CF bronchiectasis. Eur Respir J 34(Suppl. 53): 1362s.
-
(2009)
Eur Respir J
, vol.34
, pp. 1362s
-
-
Bilton, D.1
De Soyza, A.2
Haworth, C.3
Bruinenberg, P.4
Otulana, B.5
-
11
-
-
84875111653
-
Effect of a 28-day course of two different doses of once a day liposomal ciprofloxacin for inhalation on sputum Pseudomonas aeruginosa density in non-CF bronchiectasis
-
Bilton D. De Soyza A. Hayward C. Bruinenberg P. (2010) Effect of a 28-day course of two different doses of once a day liposomal ciprofloxacin for inhalation on sputum Pseudomonas aeruginosa density in non-CF bronchiectasis. Am J Respir Crit Care Med 181: A3191.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, pp. A3191
-
-
Bilton, D.1
De Soyza, A.2
Hayward, C.3
Bruinenberg, P.4
-
12
-
-
84871434086
-
Multicenter, randomized, double-blind, placebo-controlled study (ORBIT 1) to evaluate the efficacy, safety, and tolerability of once daily ciprofloxacin for inhalation in the management of Pseudomonas aeruginosa infections in patients with non-cystic fibrosis bronchiectasis
-
(, Suppl. 55, ):
-
Bilton D. Serisier D. De Soyza A. Wolfe R. Bruinenberg P. (2011) Multicenter, randomized, double-blind, placebo-controlled study (ORBIT 1) to evaluate the efficacy, safety, and tolerability of once daily ciprofloxacin for inhalation in the management of Pseudomonas aeruginosa infections in patients with non-cystic fibrosis bronchiectasis. Eur Respir J 38(Suppl. 55): 1925s.
-
(2011)
Eur Respir J
, vol.38
, pp. 1925s
-
-
Bilton, D.1
Serisier, D.2
De Soyza, A.3
Wolfe, R.4
Bruinenberg, P.5
-
13
-
-
66949159248
-
The effect of once-a-day inhaled liposomal ciprofloxacin hydrochloride on sputum bacterial density in cystic fibrosis patients with chronic pulmonary P. aeruginosa colonization
-
(, Suppl. 31, ):
-
Bruinenberg P. Otulana B. Blanchard J. Morishige R. Cipolla D. Wilson J. (2008) The effect of once-a-day inhaled liposomal ciprofloxacin hydrochloride on sputum bacterial density in cystic fibrosis patients with chronic pulmonary P. aeruginosa colonization. Pediatr Pulmonol 43(Suppl. 31): 401.
-
(2008)
Pediatr Pulmonol
, vol.43
, pp. 401
-
-
Bruinenberg, P.1
Otulana, B.2
Blanchard, J.3
Morishige, R.4
Cipolla, D.5
Wilson, J.6
-
14
-
-
84885863701
-
Effects and modulation of release rate of inhaled ciprofloxacin with liposomal formulations in healthy subjects and patients with bronchiectasis
-
(, Suppl. 54, ):
-
Bruinenberg P. Serisier D. Blanchard J. Cipolla D. Gonda I. (2010a) Effects and modulation of release rate of inhaled ciprofloxacin with liposomal formulations in healthy subjects and patients with bronchiectasis. Eur Respir J 36(Suppl. 54): 5574s.
-
(2010)
Eur Respir J
, vol.36
, pp. 5574s
-
-
Bruinenberg, P.1
Serisier, D.2
Blanchard, J.3
Cipolla, D.4
Gonda, I.5
-
15
-
-
84881546389
-
Safety, tolerability and pharmacokinetics of novel liposomal ciprofloxacin formulations for inhalation in healthy volunteers and non-cystic bronchiectasis patients
-
Bruinenberg P. Serisier D. Cipolla D. Blanchard J. (2010b) Safety, tolerability and pharmacokinetics of novel liposomal ciprofloxacin formulations for inhalation in healthy volunteers and non-cystic bronchiectasis patients. Am J Respir Crit Care Med 181: A3192.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, pp. A3192
-
-
Bruinenberg, P.1
Serisier, D.2
Cipolla, D.3
Blanchard, J.4
-
16
-
-
84861973461
-
Pharmacokinetics and antibacterial activity of inhaled liposomal ciprofloxacin hydrochloride in healthy volunteers and in cystic fibrosis (CF) patients
-
(, Suppl. 53, ):
-
Bruinenberg P. Wilson J. Serisier D. Otulana B. Blanchard J. (2009) Pharmacokinetics and antibacterial activity of inhaled liposomal ciprofloxacin hydrochloride in healthy volunteers and in cystic fibrosis (CF) patients. Eur Respir J 34(Suppl. 53): 1625s.
-
(2009)
Eur Respir J
, vol.34
, pp. 1625s
-
-
Bruinenberg, P.1
Wilson, J.2
Serisier, D.3
Otulana, B.4
Blanchard, J.5
-
17
-
-
77957665989
-
Chronic suppurative lung disease and bronchiectasis in children and adults in Australia and New Zealand
-
Chang A. Bell S. Byrnes C. Grimwood K. Holmes P. King P. (2010) Chronic suppurative lung disease and bronchiectasis in children and adults in Australia and New Zealand. Med J Aust 193: 356–365.
-
(2010)
Med J Aust
, vol.193
, pp. 356-365
-
-
Chang, A.1
Bell, S.2
Byrnes, C.3
Grimwood, K.4
Holmes, P.5
King, P.6
-
19
-
-
34249935778
-
Pharmacokinetic and pharmacodynamic efficacy of intrapulmonary administration of ciprofloxacin for the treatment of respiratory infections
-
Chono S. Tanino T. Seki T. Morimoto K. (2007) Pharmacokinetic and pharmacodynamic efficacy of intrapulmonary administration of ciprofloxacin for the treatment of respiratory infections. Drug Metab Pharmacokinet 22(2): 88–95.
-
(2007)
Drug Metab Pharmacokinet
, vol.22
, Issue.2
, pp. 88-95
-
-
Chono, S.1
Tanino, T.2
Seki, T.3
Morimoto, K.4
-
20
-
-
52949135181
-
Efficient drug delivery to alveolar macrophages and lung epithelial lining fluid following pulmonary administration of liposomal ciprofloxacin in rats with pneumonia and estimation of its antibacterial effects
-
Chono S. Tanino T. Seki T. Morimoto K. (2008) Efficient drug delivery to alveolar macrophages and lung epithelial lining fluid following pulmonary administration of liposomal ciprofloxacin in rats with pneumonia and estimation of its antibacterial effects. Drug Dev Ind Pharm 34: 1090–1096.
-
(2008)
Drug Dev Ind Pharm
, vol.34
, pp. 1090-1096
-
-
Chono, S.1
Tanino, T.2
Seki, T.3
Morimoto, K.4
-
22
-
-
0022531170
-
Inflammation: a two-edged sword ’ the model of bronchiectasis
-
Cole P. (1986) Inflammation: a two-edged sword ’ the model of bronchiectasis. Eur J Respir Dis Suppl 147: 6–15.
-
(1986)
Eur J Respir Dis Suppl
, vol.147
, pp. 6-15
-
-
Cole, P.1
-
23
-
-
0031952586
-
Pharmacokinetic-pharmacodynamic parameters: rationale for antibacterial dosing of mice and men
-
Craig W. (1998) Pharmacokinetic-pharmacodynamic parameters: rationale for antibacterial dosing of mice and men. Clin Infect Dis 26: 1–10.
-
(1998)
Clin Infect Dis
, vol.26
, pp. 1-10
-
-
Craig, W.1
-
24
-
-
84966907738
-
Frequently asked questions
-
Available at:, accessed 7 September 2012
-
Cystic Fibrosis Foundation (2011) Frequently asked questions. Available at: http://www.cff.org/AboutCF/Faqs/ ( accessed 7 September 2012).
-
(2011)
-
-
-
25
-
-
61749103937
-
Tobramycin nebulizer solution in severe COPD patients colonized with Pseudomonas aeruginosa: effects on bronchial inflammation
-
Dal Negro R. Micheletto C. Tognella S. Visconti M. Turati C. (2008) Tobramycin nebulizer solution in severe COPD patients colonized with Pseudomonas aeruginosa: effects on bronchial inflammation. Adv Ther 25: 1019–1030.
-
(2008)
Adv Ther
, vol.25
, pp. 1019-1030
-
-
Dal Negro, R.1
Micheletto, C.2
Tognella, S.3
Visconti, M.4
Turati, C.5
-
26
-
-
0022578547
-
Controversies in antimicrobial therapy: innovative methods of administration
-
Danziger L. (1986) Controversies in antimicrobial therapy: innovative methods of administration. Am J Hosp Pharm 43: 646–652.
-
(1986)
Am J Hosp Pharm
, vol.43
, pp. 646-652
-
-
Danziger, L.1
-
27
-
-
0022578320
-
Ciprofloxacin in the treatment of acute exacerbation of chronic bronchitis
-
Davies B. Maesen F. Baur C. (1986) Ciprofloxacin in the treatment of acute exacerbation of chronic bronchitis. Eur J Clin Microbiol 5: 226–231.
-
(1986)
Eur J Clin Microbiol
, vol.5
, pp. 226-231
-
-
Davies, B.1
Maesen, F.2
Baur, C.3
-
28
-
-
85026937152
-
Randomized, double-blind, placebo-controlled, multicenter study to evaluate the safety and efficacy of inhaled ciprofloxacin compared with placebo in patients with cystic fibrosis - a phase IIb study of ciprofloxacin dry powder for inhalation (DPI)
-
(, Suppl. 34, ):
-
Dorkin H. Criollo M. Reimnitz P. Alder J. Hampel B. (2011) Randomized, double-blind, placebo-controlled, multicenter study to evaluate the safety and efficacy of inhaled ciprofloxacin compared with placebo in patients with cystic fibrosis - a phase IIb study of ciprofloxacin dry powder for inhalation (DPI). Pediatr Pulmonol 46(Suppl. 34): 235.
-
(2011)
Pediatr Pulmonol
, vol.46
, pp. 235
-
-
Dorkin, H.1
Criollo, M.2
Reimnitz, P.3
Alder, J.4
Hampel, B.5
-
29
-
-
84993808654
-
Pseudomonas aeruginosa chronic lung infection model; therapeutic efficacy of ciprofloxacin-betaine after two treatment cycles
-
In:, 18th European Congress of Clinical Microbiology and Infectious Diseases, Barcelona, Spain, 19–22 April 2008, Abstract P1920
-
Endermann R. Pickbrenner A. (2008) Pseudomonas aeruginosa chronic lung infection model; therapeutic efficacy of ciprofloxacin-betaine after two treatment cycles. In: 18th European Congress of Clinical Microbiology and Infectious Diseases, Barcelona, Spain, 19–22 April 2008, Abstract P1920.
-
(2008)
-
-
Endermann, R.1
Pickbrenner, A.2
-
30
-
-
84866372948
-
European committee on antimicrobial susceptibility testing: breakpoint tables for interpretation of MICs and zone diameters, version 2.0
-
Available at:, accessed 8 September 2012
-
European Committee on Antimicrobial Susceptibility Testing (2012) European committee on antimicrobial susceptibility testing: breakpoint tables for interpretation of MICs and zone diameters, version 2.0. Available at: http://www.eucast.org/fileadmin/src/media/PDFs/EUCAST_files/Breakpoint_tables/Breakpoint_table_v_2.0_120221.pdf ( accessed 8 September 2012).
-
(2012)
-
-
-
31
-
-
84885859038
-
Tobi Podhaler (EPAR Product Information)
-
European Medicines Agency (2011) Tobi Podhaler (EPAR Product Information).
-
(2011)
-
-
-
32
-
-
84885855014
-
Colobreathe (EPAR Product Information)
-
European Medicines Agency (2012) Colobreathe (EPAR Product Information).
-
(2012)
-
-
-
33
-
-
80051907331
-
Bronchiectasis: new approaches to diagnosis and management
-
Feldman C. (2011) Bronchiectasis: new approaches to diagnosis and management. Clin Chest Med 32: 535–546.
-
(2011)
Clin Chest Med
, vol.32
, pp. 535-546
-
-
Feldman, C.1
-
34
-
-
0036198938
-
The rationale for aerosolized antibiotics
-
Flume P. Klepser M. (2002) The rationale for aerosolized antibiotics. Pharmacotherapy 22(3 Pt 2): 71S–79S.
-
(2002)
Pharmacotherapy
, vol.22
, Issue.3 Pt 2
, pp. 71S-79S
-
-
Flume, P.1
Klepser, M.2
-
36
-
-
84993699477
-
-
Dartford, UK: Forest Laboratories UK Limited
-
Forest Laboratories UK Limited (2004) Colomycin (Patient Information Leaflet). Dartford, UK: Forest Laboratories UK Limited.
-
(2004)
Colomycin (Patient Information Leaflet)
-
-
-
37
-
-
40649087414
-
Mucosal inflammation in idiopathic bronchiectasis: cellular and molecular mechanisms
-
Fuschillo S. De Felice A. Balzano G. (2008) Mucosal inflammation in idiopathic bronchiectasis: cellular and molecular mechanisms. Eur Respir J 31: 396–406.
-
(2008)
Eur Respir J
, vol.31
, pp. 396-406
-
-
Fuschillo, S.1
De Felice, A.2
Balzano, G.3
-
38
-
-
84884581995
-
-
Foster City, CA: Gilead Sciences, Inc
-
Gilead Sciences, Inc. (2012) Cayston (Prescribing Information). Foster City, CA: Gilead Sciences, Inc.
-
(2012)
Cayston (Prescribing Information)
-
-
-
39
-
-
84858205422
-
Risk factors for morbidity and death in non-cystic fibrosis bronchiectasis: a retrospective cross-sectional analysis of CT diagnosed bronchiectatic patients
-
Goeminne P. Scheers H. Decraene A. Seys S. Dupont L. (2012) Risk factors for morbidity and death in non-cystic fibrosis bronchiectasis: a retrospective cross-sectional analysis of CT diagnosed bronchiectatic patients. Resp Res 13: 21.
-
(2012)
Resp Res
, vol.13
, pp. 21
-
-
Goeminne, P.1
Scheers, H.2
Decraene, A.3
Seys, S.4
Dupont, L.5
-
40
-
-
0034917313
-
Steady-state plasma and intrapulmonary concentrations of levofloxacin and ciprofloxacin in healthy adult subjects
-
Gotfried M. Danziger L. Rodvold K. (2001) Steady-state plasma and intrapulmonary concentrations of levofloxacin and ciprofloxacin in healthy adult subjects. Chest 119: 1114–1122.
-
(2001)
Chest
, vol.119
, pp. 1114-1122
-
-
Gotfried, M.1
Danziger, L.2
Rodvold, K.3
-
41
-
-
0022553714
-
Ciprofloxacin in acute exacerbations of chronic bronchitis
-
Hoogkamp-Korstanje J. Klein S. (1986) Ciprofloxacin in acute exacerbations of chronic bronchitis. J Antimicrob Chemother 18: 407–413.
-
(1986)
J Antimicrob Chemother
, vol.18
, pp. 407-413
-
-
Hoogkamp-Korstanje, J.1
Klein, S.2
-
42
-
-
84993763856
-
A randomized controlled study to investigate the safety and pharmacokinetics of multiple doses of ciprofloxacin dry powder for inhalation in japanese patients with moderate to severe COPD
-
Kadota J. Tokimatsu I. Hiramatsu K. Morimoto T. Imai H. Suzaki Y. (2012) A randomized controlled study to investigate the safety and pharmacokinetics of multiple doses of ciprofloxacin dry powder for inhalation in japanese patients with moderate to severe COPD. Am J Respir Crit Care Med 185: A2273.
-
(2012)
Am J Respir Crit Care Med
, vol.185
, pp. A2273
-
-
Kadota, J.1
Tokimatsu, I.2
Hiramatsu, K.3
Morimoto, T.4
Imai, H.5
Suzaki, Y.6
-
43
-
-
77949530185
-
The pathophysiology of bronchiectasis
-
King P. (2009) The pathophysiology of bronchiectasis. Int J Chron Obstruct Pulmon Dis 4: 411–419.
-
(2009)
Int J Chron Obstruct Pulmon Dis
, vol.4
, pp. 411-419
-
-
King, P.1
-
45
-
-
84993694338
-
Pharmacodynamics of simulated ciprofloxacin sputum levels following a new dry powder inhalation therapy in an in vitro hollow fiber model
-
(, Suppl. 31, ):
-
Knezevic I. Schmidt S. Weskott G. Glenschek-Sieberth M. (2008) Pharmacodynamics of simulated ciprofloxacin sputum levels following a new dry powder inhalation therapy in an in vitro hollow fiber model. Pediatr Pulmonol 43(Suppl. 31): 283.
-
(2008)
Pediatr Pulmonol
, vol.43
, pp. 283
-
-
Knezevic, I.1
Schmidt, S.2
Weskott, G.3
Glenschek-Sieberth, M.4
-
46
-
-
77952911090
-
Consensus summary of aerosolized antimicrobial agents: application of guideline criteria. Insights from the Society of Infectious Diseases Pharmacists
-
Le J. Ashley E. Neuhauser M. Brown J. Gentry C. Klepser M. (2010) Consensus summary of aerosolized antimicrobial agents: application of guideline criteria. Insights from the Society of Infectious Diseases Pharmacists. Pharmacotherapy 30: 562–584.
-
(2010)
Pharmacotherapy
, vol.30
, pp. 562-584
-
-
Le, J.1
Ashley, E.2
Neuhauser, M.3
Brown, J.4
Gentry, C.5
Klepser, M.6
-
48
-
-
36348949002
-
Factors associated with lung function decline in adult patients with stable non-cystic fibrosis bronchiectasis
-
Martinez-Garcia M. Soler-Cataluna J. Perpina-Tordera M. Roman-Sanchez P. Soriano J. (2007) Factors associated with lung function decline in adult patients with stable non-cystic fibrosis bronchiectasis. Chest 132: 1565–1572.
-
(2007)
Chest
, vol.132
, pp. 1565-1572
-
-
Martinez-Garcia, M.1
Soler-Cataluna, J.2
Perpina-Tordera, M.3
Roman-Sanchez, P.4
Soriano, J.5
-
49
-
-
84860994240
-
Chapter 93 Ciprofloxacin
-
In:, Grayson, M., Crowe, S., McCarthy, J., Mills, J., Mouton, J., Norrby, S., (eds), 6th edn., London: Hodder Arnold, pp
-
McCormack J. Grayson M. (2010) Chapter 93 Ciprofloxacin. In: Grayson M. Crowe S. McCarthy J. Mills J. Mouton J. Norrby S. (eds) Kucers–: The Use of Antibiotics, 6th edn. London: Hodder Arnold, pp. 1265–1346.
-
(2010)
Kucers–: The Use of Antibiotics
, pp. 1265-1346
-
-
McCormack, J.1
Grayson, M.2
-
50
-
-
84885865997
-
Promixin (Public Assessment Report)
-
Medicines and Healthcare Products Regulatory Agency (2011) Promixin (Public Assessment Report).
-
(2011)
-
-
-
51
-
-
77951894250
-
New treatment options for bronchiectasis
-
Metersky M. (2010) New treatment options for bronchiectasis. Ther Adv Respir Dis 4: 93–99.
-
(2010)
Ther Adv Respir Dis
, vol.4
, pp. 93-99
-
-
Metersky, M.1
-
52
-
-
0028820334
-
Clinical, pathophysiologic, and microbiologic characterization of bronchiectasis in an aging cohort
-
Nicotra M. Rivera M. Dale A. Shepherd R. Carter R. (1995) Clinical, pathophysiologic, and microbiologic characterization of bronchiectasis in an aging cohort. Chest 108: 955–961.
-
(1995)
Chest
, vol.108
, pp. 955-961
-
-
Nicotra, M.1
Rivera, M.2
Dale, A.3
Shepherd, R.4
Carter, R.5
-
53
-
-
84884548148
-
-
East Hanover, NJ: Novartis Pharmaceuticals Corporation
-
Novartis Pharmaceuticals Corporation (2009) TOBI (Prescribing Information). East Hanover, NJ: Novartis Pharmaceuticals Corporation.
-
(2009)
TOBI (Prescribing Information)
-
-
-
54
-
-
77951907669
-
A placebo-controlled study of liposomal amikacin for inhalation nebulized once daily in the treatment of bronchiectasis patients with chronic Pseudomonas aeruginosa lung infection
-
(, Suppl. 53, ):
-
O–Donnell A. Swarnakar R. Yashina L. Nikolova P. Marinov R. Waghray P. (2009) A placebo-controlled study of liposomal amikacin for inhalation nebulized once daily in the treatment of bronchiectasis patients with chronic Pseudomonas aeruginosa lung infection. Eur Respir J 34(Suppl. 53): 1361.
-
(2009)
Eur Respir J
, vol.34
, pp. 1361
-
-
O–Donnell, A.1
Swarnakar, R.2
Yashina, L.3
Nikolova, P.4
Marinov, R.5
Waghray, P.6
-
55
-
-
21844444791
-
Antimicrobial safety: focus on fluoroquinolones
-
(, Suppl. 2, ):
-
Owens R. Ambrose P. (2005) Antimicrobial safety: focus on fluoroquinolones. Clin Infect Dis 41(Suppl. 2): S144's157.
-
(2005)
Clin Infect Dis
, vol.41
, pp. S144-S157
-
-
Owens, R.1
Ambrose, P.2
-
56
-
-
77955287226
-
British Thoracic Society guideline for non-CF bronchiectasis
-
(, Suppl. 1, ):
-
Pasteur M. Bilton D. Hill A. and the British Thoracic Society Bronchiectasis non-CF Guideline Group (2010) British Thoracic Society guideline for non-CF bronchiectasis. Thorax 65(Suppl. 1): i1–i58.
-
(2010)
Thorax
, vol.65
, pp. i1-i58
-
-
Pasteur, M.1
Bilton, D.2
Hill, A.3
-
58
-
-
84899782510
-
Bronchiectasis–diagnosis and treatment
-
Rademacher J. Welte T. (2011) Bronchiectasis–diagnosis and treatment. Dtsch Arztebl Int 108: 809–815.
-
(2011)
Dtsch Arztebl Int
, vol.108
, pp. 809-815
-
-
Rademacher, J.1
Welte, T.2
-
59
-
-
0028095088
-
Efficacy and safety of long-term ciprofloxacin in the management of severe bronchiectasis
-
Rayner C. Tillotson G. Cole P. Wilson R. (1994) Efficacy and safety of long-term ciprofloxacin in the management of severe bronchiectasis. J Antimicrob Chemother 34: 149–156.
-
(1994)
J Antimicrob Chemother
, vol.34
, pp. 149-156
-
-
Rayner, C.1
Tillotson, G.2
Cole, P.3
Wilson, R.4
-
60
-
-
0024267448
-
Lack of unique ciprofloxacin pharmacokinetic characteristics in patients with cystic fibrosis
-
Reed M. Stern R. Myers C. Yamashita T. Blumer J. (1988) Lack of unique ciprofloxacin pharmacokinetic characteristics in patients with cystic fibrosis. J Clin Pharmacol 28: 691–699.
-
(1988)
J Clin Pharmacol
, vol.28
, pp. 691-699
-
-
Reed, M.1
Stern, R.2
Myers, C.3
Yamashita, T.4
Blumer, J.5
-
61
-
-
80052514361
-
Penetration of anti-infective agents into pulmonary epithelial lining fluid
-
Rodvold K. George J. Yoo L. (2011) Penetration of anti-infective agents into pulmonary epithelial lining fluid. Clin Pharmacokinet 50: 637–664.
-
(2011)
Clin Pharmacokinet
, vol.50
, pp. 637-664
-
-
Rodvold, K.1
George, J.2
Yoo, L.3
-
62
-
-
77957854936
-
Trends and burden of bronchiectasis-associated hospitalizations in the United States, 1993-2006
-
Seitz A. Olivier K. Steiner C. Montes de Oca R. Holland S. Prevots D. (2010) Trends and burden of bronchiectasis-associated hospitalizations in the United States, 1993-2006. Chest 138: 944–949.
-
(2010)
Chest
, vol.138
, pp. 944-949
-
-
Seitz, A.1
Olivier, K.2
Steiner, C.3
Montes, D.4
Oca, R.5
Holland, S.6
Prevots, D.7
-
63
-
-
84861989861
-
Inhaled antibiotics for lower respiratory tract infections: focus on ciprofloxacin
-
Serisier D. (2012) Inhaled antibiotics for lower respiratory tract infections: focus on ciprofloxacin. Drugs Today (Barc) 48: 339–351.
-
(2012)
Drugs Today (Barc)
, vol.48
, pp. 339-351
-
-
Serisier, D.1
-
64
-
-
84885866001
-
An optimized inhaled ciprofloxacin formulation DRCFI (dual release ciprofloxacin for inhalation) enhances antibiotic lung concentrations and antimicrobial effect in non-CF bronchiectasis (Non-CF BE)
-
Serisier D. Bilton D. De Soyza T. Gonda I. (2012) An optimized inhaled ciprofloxacin formulation DRCFI (dual release ciprofloxacin for inhalation) enhances antibiotic lung concentrations and antimicrobial effect in non-CF bronchiectasis (Non-CF BE). Am J Respir Crit Care Med 185: A3659.
-
(2012)
Am J Respir Crit Care Med
, vol.185
, pp. A3659
-
-
Serisier, D.1
Bilton, D.2
De Soyza, T.3
Gonda, I.4
-
65
-
-
84861995055
-
Inhaled liposomal ciprofloxacin significantly reduces sputum Pseudomonas aeruginosa (PA) density and increases time to first exacerbation in a 168 day placebo controlled study in non-cystic fibrosis bronchiectasis (Non-CF BE)
-
Serisier D. Kolbe J. Greville H. Gonda I. Bruinenberg P. (2011a) Inhaled liposomal ciprofloxacin significantly reduces sputum Pseudomonas aeruginosa (PA) density and increases time to first exacerbation in a 168 day placebo controlled study in non-cystic fibrosis bronchiectasis (Non-CF BE). Am J Respir Crit Care Med 183: A4866.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. A4866
-
-
Serisier, D.1
Kolbe, J.2
Greville, H.3
Gonda, I.4
Bruinenberg, P.5
-
66
-
-
84871439951
-
Dual release ciprofloxacin for inhalation (DRCFI) reduces sputum Pseudomonas aeruginosa (Pa) density and delays time to infective pulmonary exacerbation in non-cystic fibrosis (CF) Bronchiectasis (BE)
-
(, Suppl. 55, ):
-
Serisier D. Thompson P. Greville H. Kolbe J. Bruinenberg P. (2011b) Dual release ciprofloxacin for inhalation (DRCFI) reduces sputum Pseudomonas aeruginosa (Pa) density and delays time to infective pulmonary exacerbation in non-cystic fibrosis (CF) Bronchiectasis (BE). Eur Respir J 38(Suppl. 55): 1928s.
-
(2011)
Eur Respir J
, vol.38
, pp. 1928s
-
-
Serisier, D.1
Thompson, P.2
Greville, H.3
Kolbe, J.4
Bruinenberg, P.5
-
68
-
-
84993684107
-
Ciprofloxacin Pulmosphere inhalational powder: a healthy volunteer research study
-
In:, American Thoracic Society International Conference, Toronto, Canada, 16–21 May 2008, [poster]
-
Stass H. Baumann-Noss S. Delesen H. Nagelschmitz J. Willman S. Edginton A. (2008a) Ciprofloxacin Pulmosphere inhalational powder: a healthy volunteer research study. In: American Thoracic Society International Conference, Toronto, Canada, 16–21 May 2008 [poster].
-
(2008)
-
-
Stass, H.1
Baumann-Noss, S.2
Delesen, H.3
Nagelschmitz, J.4
Willman, S.5
Edginton, A.6
-
69
-
-
66949153801
-
Pharmacokinetics of ciprofloxacin PulmoSphere® inhalational powder
-
(, Suppl. 2, ):, Abstract A103
-
Stass H. Baumann-Noss S. Delesen H. Nagelschmitz J. Willmann S. Edginton A. (2008b) Pharmacokinetics of ciprofloxacin PulmoSphere® inhalational powder. J Cyst Fibros 7(Suppl. 2): S26, Abstract A103.
-
(2008)
J Cyst Fibros
, vol.7
, pp. S26
-
-
Stass, H.1
Baumann-Noss, S.2
Delesen, H.3
Nagelschmitz, J.4
Willmann, S.5
Edginton, A.6
-
70
-
-
84877094120
-
Safety and pharmacokinetics of inhaled dry powder ciprofloxacin after single and multiple inhalations in patients with cystic fibrosis
-
(, Suppl. 31, ):
-
Stass H. Ludwig M. Nagelschmitz J. Staab D. (2008c) Safety and pharmacokinetics of inhaled dry powder ciprofloxacin after single and multiple inhalations in patients with cystic fibrosis. Pediatr Pulmonol 43(Suppl. 31): 282.
-
(2008)
Pediatr Pulmonol
, vol.43
, pp. 282
-
-
Stass, H.1
Ludwig, M.2
Nagelschmitz, J.3
Staab, D.4
-
71
-
-
77955017576
-
Safety, tolerability and pharmacokinetics of ciprofloxacin dry powder for inhalation in adolescent patients with CF
-
(, Suppl. 32, ):
-
Stass H. Nagelschmitz J. Posselt H. (2009) Safety, tolerability and pharmacokinetics of ciprofloxacin dry powder for inhalation in adolescent patients with CF. Pediatr Pulmonol 44(Suppl. 32): 258.
-
(2009)
Pediatr Pulmonol
, vol.44
, pp. 258
-
-
Stass, H.1
Nagelschmitz, J.2
Posselt, H.3
-
72
-
-
84993734878
-
Safety and pharmacokinetics of two dose strengths of ciprofloxacin dry powder for inhalation (DPI) in patients with moderate to severe COPD
-
In:, The 2012 European Respiratory Society Annual Congress, Vienna, Austria, 1–5 September 2012, Abstract 2817
-
Stass H. Nagelschmitz J. Watz H. Kirsten A. (2012) Safety and pharmacokinetics of two dose strengths of ciprofloxacin dry powder for inhalation (DPI) in patients with moderate to severe COPD. In: The 2012 European Respiratory Society Annual Congress, Vienna, Austria, 1–5 September 2012, Abstract 2817.
-
(2012)
-
-
Stass, H.1
Nagelschmitz, J.2
Watz, H.3
Kirsten, A.4
-
73
-
-
84861969259
-
Safety, tolerability and pharmacokinetics of ciprofloxacin dry powder for inhalation in patients with mild to moderate chronic obstructive pulmonary disease: a randomized controlled trial
-
Stass H. Nagelschmitz J. Weimann B. Timmer W. (2011) Safety, tolerability and pharmacokinetics of ciprofloxacin dry powder for inhalation in patients with mild to moderate chronic obstructive pulmonary disease: a randomized controlled trial. Am J Respir Crit Care Med 183: A3730.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. A3730
-
-
Stass, H.1
Nagelschmitz, J.2
Weimann, B.3
Timmer, W.4
-
74
-
-
84877089118
-
Safety, tolerability, and pharmacokinetics of a single dose of ciprofloxacin dry powder for inhalation (ciprofloxacin DPI) in Japanese patients with mild to moderate chronic obstructive pulmonary disease: a randomized controlled trial
-
Tokimatsu I. Hiramatsu K. Morimoto T. Imai H. Suzaki Y. Stass H. (2011) Safety, tolerability, and pharmacokinetics of a single dose of ciprofloxacin dry powder for inhalation (ciprofloxacin DPI) in Japanese patients with mild to moderate chronic obstructive pulmonary disease: a randomized controlled trial. Am J Respir Crit Care Med 183: A3105.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. A3105
-
-
Tokimatsu, I.1
Hiramatsu, K.2
Morimoto, T.3
Imai, H.4
Suzaki, Y.5
Stass, H.6
-
76
-
-
0030879813
-
Effect of sputum bacteriology on the quality of life of patients with bronchiectasis
-
Wilson C. Jones P. O–Leary C. Hansell D. Cole P. Wilson R. (1997) Effect of sputum bacteriology on the quality of life of patients with bronchiectasis. Eur Respir J 10: 1754–1760.
-
(1997)
Eur Respir J
, vol.10
, pp. 1754-1760
-
-
Wilson, C.1
Jones, P.2
O–Leary, C.3
Hansell, D.4
Cole, P.5
Wilson, R.6
|