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Volumn 8, Issue , 2013, Pages 3521-3531

Codelivery of curcumin and doxorubicin by MPEG-PCL results in improved efficacy of systemically administered chemotherapy in mice with lung cancer

Author keywords

Cancer; Curcumin; Doxorubicin; Methoxy poly(ethylene glycol); Micelles; Poly(caprolactone); Treatment

Indexed keywords

COPOLYMER; CURCUMIN; DOXORUBICIN; METHOXY POLY(ETHYLENE GLYCOL) POLY(CAPROLACTONE) COPOLYMER; UNCLASSIFIED DRUG;

EID: 84884548821     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S45250     Document Type: Article
Times cited : (95)

References (45)
  • 1
    • 0037305821 scopus 로고    scopus 로고
    • Curcumin (diferuloyl-methane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis
    • Bharti AC, Donato N, Singh S, Aggarwal BB. Curcumin (diferuloyl-methane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis. Blood. 2003;101:1053-1062.
    • (2003) Blood , vol.101 , pp. 1053-1062
    • Bharti, A.C.1    Donato, N.2    Singh, S.3    Aggarwal, B.B.4
  • 2
    • 0033568674 scopus 로고    scopus 로고
    • Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity
    • Jobin C, Bradham CA, Russo MP, et al. Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity. J Immunol. 1999;163:3474-3483.
    • (1999) J Immunol , vol.163 , pp. 3474-3483
    • Jobin, C.1    Bradham, C.A.2    Russo, M.P.3
  • 3
    • 42249102138 scopus 로고    scopus 로고
    • Curcumin sensitizes human colorectal cancer xenografts in nude mice to gamma-radiation by targeting nuclear factor-kappaB-regulated gene products
    • Kunnumakkara AB, Diagaradjane P, Guha S, et al. Curcumin sensitizes human colorectal cancer xenografts in nude mice to gamma-radiation by targeting nuclear factor-kappaB-regulated gene products. Clin Cancer Res. 2008;14:2128-2136.
    • (2008) Clin Cancer Res , vol.14 , pp. 2128-2136
    • Kunnumakkara, A.B.1    Diagaradjane, P.2    Guha, S.3
  • 5
    • 19344368071 scopus 로고    scopus 로고
    • Chemopreventive and therapeutic effects of curcumin
    • Duvoix A, Blasius R, Delhalle S, et al. Chemopreventive and therapeutic effects of curcumin. Cancer Lett. 2005;223:181-190.
    • (2005) Cancer Lett , vol.223 , pp. 181-190
    • Duvoix, A.1    Blasius, R.2    Delhalle, S.3
  • 6
    • 0036645522 scopus 로고    scopus 로고
    • Dietary cur-cumin inhibits chemotherapy-induced apoptosis in models of human breast cancer
    • Correspondence re: Somasundaram et al
    • Mitchell TM. Correspondence re: Somasundaram et al. Dietary cur-cumin inhibits chemotherapy-induced apoptosis in models of human breast cancer. Cancer Res. 2002;62:3868-3875.
    • (2002) Cancer Res , vol.62 , pp. 3868-3875
    • Mitchell, T.M.1
  • 8
    • 1242352473 scopus 로고    scopus 로고
    • Role of curcumin and the inhibition of NF-kappaB in the onset of chemotherapy-induced mucosal barrier injury
    • van't Land B, Blijlevens NM, Marteijn J, et al. Role of curcumin and the inhibition of NF-kappaB in the onset of chemotherapy-induced mucosal barrier injury. Leukemia. 2004:18:276-284.
    • (2004) Leukemia , vol.18 , pp. 276-284
    • van't land, B.1    Blijlevens, N.M.2    Marteijn, J.3
  • 9
    • 29344455140 scopus 로고    scopus 로고
    • Synergistic inhibitory effects of cur-cumin and 5-fluorouracil on the growth of the human colon cancer cell line HT-29
    • Du B, Jiang L, Xia Q, Zhong L. Synergistic inhibitory effects of cur-cumin and 5-fluorouracil on the growth of the human colon cancer cell line HT-29. Chemotherapy. 2006;52:23-28.
    • (2006) Chemotherapy , vol.52 , pp. 23-28
    • Du, B.1    Jiang, L.2    Xia, Q.3    Zhong, L.4
  • 10
    • 36849018017 scopus 로고    scopus 로고
    • Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating EGFR and IGF-1R
    • Patel BB, Sengupta R, Qazi S, et al. Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating EGFR and IGF-1R. Int J Cancer. 2008;122: 267-273.
    • (2008) Int J Cancer , vol.122 , pp. 267-273
    • Patel, B.B.1    Sengupta, R.2    Qazi, S.3
  • 11
    • 0032537814 scopus 로고    scopus 로고
    • Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin
    • Chen YR, Tan TH. Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin. Oncogene. 1998;17:173-178.
    • (1998) Oncogene , vol.17 , pp. 173-178
    • Chen, Y.R.1    Tan, T.H.2
  • 12
    • 0031840433 scopus 로고    scopus 로고
    • Curcumin is an in vivo inhibitor of angiogenesis
    • Arbiser JL, Klauber N, Rohan R, et al. Curcumin is an in vivo inhibitor of angiogenesis. Mol Med. 1998;4:376-383.
    • (1998) Mol Med , vol.4 , pp. 376-383
    • Arbiser, J.L.1    Klauber, N.2    Rohan, R.3
  • 13
    • 34250654084 scopus 로고    scopus 로고
    • Curcumin inhibits tumor growth and angiogenesis in ovarian carcinoma by targeting the nuclear factor-kappaB pathway
    • Lin YG, Kunnumakkara AB, Nair A, et al. Curcumin inhibits tumor growth and angiogenesis in ovarian carcinoma by targeting the nuclear factor-kappaB pathway. Clin Cancer Res. 2007;13:3423-3430.
    • (2007) Clin Cancer Res , vol.13 , pp. 3423-3430
    • Lin, Y.G.1    Kunnumakkara, A.B.2    Nair, A.3
  • 14
    • 0035370750 scopus 로고    scopus 로고
    • Therapeutic potential of curcumin in human prostate cancer. III. Curcumin inhibits proliferation, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in vivo
    • Dorai T, Cao YC, Dorai B, Buttyan R, Katz AE. Therapeutic potential of curcumin in human prostate cancer. III. Curcumin inhibits proliferation, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in vivo. Prostate. 2001;47:293-303.
    • (2001) Prostate , vol.47 , pp. 293-303
    • Dorai, T.1    Cao, Y.C.2    Dorai, B.3    Buttyan, R.4    Katz, A.E.5
  • 15
    • 51349137454 scopus 로고    scopus 로고
    • Curcumin inhibits pro-liferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins
    • Kunnumakkara AB, Anand P, Aggarwal BB. Curcumin inhibits pro-liferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins. Cancer Lett. 2008;269:199-225.
    • (2008) Cancer Lett , vol.269 , pp. 199-225
    • Kunnumakkara, A.B.1    Anand, P.2    Aggarwal, B.B.3
  • 16
    • 0032815637 scopus 로고    scopus 로고
    • Curcumin mediated apoptosis in AK-5 tumor cells involves the production of reactive oxygen intermediates
    • Bhaumik S, Anjum R, Rangaraj N, Pardhasaradhi BV, Khar A. Curcumin mediated apoptosis in AK-5 tumor cells involves the production of reactive oxygen intermediates. FEBS Lett. 1999;456:311-314.
    • (1999) FEBS Lett , vol.456 , pp. 311-314
    • Bhaumik, S.1    Anjum, R.2    Rangaraj, N.3    Pardhasaradhi, B.V.4    Khar, A.5
  • 17
    • 30044446136 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) down-regulates expres-sion of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation
    • Aggarwal S, Ichikawa H, Takada Y, Sandur SK, Shishodia S, Aggarwal BB. Curcumin (diferuloylmethane) down-regulates expres-sion of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation. Mol Pharmacol. 2006;69:195-206.
    • (2006) Mol Pharmacol , vol.69 , pp. 195-206
    • Aggarwal, S.1    Ichikawa, H.2    Takada, Y.3    Sandur, S.K.4    Shishodia, S.5    Aggarwal, B.B.6
  • 18
    • 0033053430 scopus 로고    scopus 로고
    • Anti-metastatic activity of curcumin and catechin
    • Menon LG, Kuttan R, Kuttan G. Anti-metastatic activity of curcumin and catechin. Cancer Lett. 1999;141:159-165.
    • (1999) Cancer Lett , vol.141 , pp. 159-165
    • Menon, L.G.1    Kuttan, R.2    Kuttan, G.3
  • 19
    • 34248205135 scopus 로고    scopus 로고
    • Polymeric nanoparticle-encapsulated curcumin (nanocurcumin): A novel strategy for human cancer therapy
    • Bisht S, Feldmann G, Soni S, et al. Polymeric nanoparticle-encapsulated curcumin (nanocurcumin): a novel strategy for human cancer therapy. J Nanobiotechnology. 2007;5:3.
    • (2007) J Nanobiotechnology , vol.5 , pp. 3
    • Bisht, S.1    Feldmann, G.2    Soni, S.3
  • 21
    • 77954848597 scopus 로고    scopus 로고
    • Curcumin, resveratrol and flavonoids as anti-inflammatory, cyto- and DNA-protective dietary compounds
    • Bisht K, Wagner KH, Bulmer AC. Curcumin, resveratrol and flavonoids as anti-inflammatory, cyto- and DNA-protective dietary compounds. Toxicology. 2010;278:88-100.
    • (2010) Toxicology , vol.278 , pp. 88-100
    • Bisht, K.1    Wagner, K.H.2    Bulmer, A.C.3
  • 22
    • 77953152280 scopus 로고    scopus 로고
    • Injectable sustained release microparticles of curcumin: A new concept for cancer chemoprevention
    • Shahani K, Swaminathan SK, Freeman D, Blum A, Ma L, Panyam J. Injectable sustained release microparticles of curcumin: a new concept for cancer chemoprevention. Cancer Res. 2010;70:4443-4452.
    • (2010) Cancer Res , vol.70 , pp. 4443-4452
    • Shahani, K.1    Swaminathan, S.K.2    Freeman, D.3    Blum, A.4    Ma, L.5    Panyam, J.6
  • 23
    • 68649118183 scopus 로고    scopus 로고
    • Layer-by-layer-coated gelatin nanoparticles as a vehicle for delivery of natural polyphenols
    • Shutava TG, Balkundi SS, Vangala P, et al. Layer-by-layer-coated gelatin nanoparticles as a vehicle for delivery of natural polyphenols. ACS Nano. 2009;3:1877-1885.
    • (2009) ACS Nano , vol.3 , pp. 1877-1885
    • Shutava, T.G.1    Balkundi, S.S.2    Vangala, P.3
  • 24
    • 77950145605 scopus 로고    scopus 로고
    • Aptamer-based tumor-targeted drug delivery for photodynamic therapy
    • Shieh YA, Yang SJ, Wei MF, Shieh MJ. Aptamer-based tumor-targeted drug delivery for photodynamic therapy. ACS Nano. 2010;4: 1433-1442.
    • (2010) ACS Nano , vol.4 , pp. 1433-1442
    • Shieh, Y.A.1    Yang, S.J.2    Wei, M.F.3    Shieh, M.J.4
  • 25
    • 78049401949 scopus 로고    scopus 로고
    • Preparation, characterization and applications of low-molecular-weight alginate-oligochitosan nanocapsules
    • Wang T, He N. Preparation, characterization and applications of low-molecular-weight alginate-oligochitosan nanocapsules. Nanoscale. 2010;2:230-239.
    • (2010) Nanoscale , vol.2 , pp. 230-239
    • Wang, T.1    He, N.2
  • 26
    • 79952118664 scopus 로고    scopus 로고
    • Therapy for cerebral ischemic injury with erythropoietin-containing nanoparticles
    • He N, Wang T, Jiang L, Wang D, Hu Y, Zhang L. Therapy for cerebral ischemic injury with erythropoietin-containing nanoparticles. J Nanosci Nanotechnol. 2010;10:5320-5323.
    • (2010) J Nanosci Nanotechnol , vol.10 , pp. 5320-5323
    • He, N.1    Wang, T.2    Jiang, L.3    Wang, D.4    Hu, Y.5    Zhang, L.6
  • 27
    • 42049110950 scopus 로고    scopus 로고
    • Application of nanotechnology in cancer therapy and imaging
    • Wang X, Yang L, Chen ZG, Shin DM. Application of nanotechnology in cancer therapy and imaging. CA Cancer J Clin. 2008;58:97-110.
    • (2008) CA Cancer J Clin , vol.58 , pp. 97-110
    • Wang, X.1    Yang, L.2    Chen, Z.G.3    Shin, D.M.4
  • 28
    • 70349232194 scopus 로고    scopus 로고
    • Biodegradable poly(epsilon-caprolactone)- poly(ethylene glycol) copolymers as drug delivery system
    • Wei X, Gong C, Gou M, et al. Biodegradable poly(epsilon-caprolactone)- poly(ethylene glycol) copolymers as drug delivery system. Int J Pharm. 2009;381:1-18.
    • (2009) Int J Pharm , vol.381 , pp. 1-18
    • Wei, X.1    Gong, C.2    Gou, M.3
  • 29
    • 79959343424 scopus 로고    scopus 로고
    • PCL/PEG copolymeric nanoparticles: Potential nanoplatforms for anticancer agent delivery
    • Gou M, Wei X, Men K, et al. PCL/PEG copolymeric nanoparticles: potential nanoplatforms for anticancer agent delivery. Curr Drug Targets. 2011;12:1131-1150.
    • (2011) Curr Drug Targets , vol.12 , pp. 1131-1150
    • Gou, M.1    Wei, X.2    Men, K.3
  • 30
    • 84870381912 scopus 로고    scopus 로고
    • A systemic administration of liposomal curcumin inhibits radiation pneumonitis and sensitizes lung carcinoma to radiation
    • Shi HS, Gao X, Li D, et al. A systemic administration of liposomal curcumin inhibits radiation pneumonitis and sensitizes lung carcinoma to radiation. Int J Nanomedicine. 2012;7:2601-2611.
    • (2012) Int J Nanomedicine , vol.7 , pp. 2601-2611
    • Shi, H.S.1    Gao, X.2    Li, D.3
  • 31
    • 37849006806 scopus 로고    scopus 로고
    • Design and development of water-soluble curcumin conjugates as potential anticancer agents
    • Safavy A, Raisch KP, Mantena S, et al. Design and development of water-soluble curcumin conjugates as potential anticancer agents. J Med Chem. 2007;50:6284-6288.
    • (2007) J Med Chem , vol.50 , pp. 6284-6288
    • Safavy, A.1    Raisch, K.P.2    Mantena, S.3
  • 32
    • 80052593285 scopus 로고    scopus 로고
    • Preparation of curcumin loaded poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) nanofibers and their in vitro antitumor activity against glioma 9L cells
    • Guo G, Fu S, Zhou L, et al. Preparation of curcumin loaded poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) nanofibers and their in vitro antitumor activity against glioma 9L cells. Nanoscale. 2011;3:3825-3832.
    • (2011) Nanoscale , vol.3 , pp. 3825-3832
    • Guo, G.1    Fu, S.2    Zhou, L.3
  • 33
    • 79952114779 scopus 로고    scopus 로고
    • A novel drug and gene co-delivery system based on poly(epsilon-caprolactone)-poly(ethylene glycol)-poly(epsilon-caprolactone) grafted polyethyleneimine micelle
    • Men K, Gou ML, Guo QF, et al. A novel drug and gene co-delivery system based on poly(epsilon-caprolactone)-poly(ethylene glycol)-poly(epsilon-caprolactone) grafted polyethyleneimine micelle. J Nanosci Nanotechnol. 2010;10:7958-7964.
    • (2010) J Nanosci Nanotechnol , vol.10 , pp. 7958-7964
    • Men, K.1    Gou, M.L.2    Guo, Q.F.3
  • 34
    • 68149183600 scopus 로고    scopus 로고
    • Self-assembled hydrophobic honokiol loaded MPEG-PCL diblock copolymer micelles
    • Gou M, Zheng X, Men K, et al. Self-assembled hydrophobic honokiol loaded MPEG-PCL diblock copolymer micelles. Pharm Res. 2009;26:2164-2173.
    • (2009) Pharm Res , vol.26 , pp. 2164-2173
    • Gou, M.1    Zheng, X.2    Men, K.3
  • 35
    • 77954164403 scopus 로고    scopus 로고
    • Silencing of pkm2 increases the efficacy of docetaxel in human lung cancer xenografts in mice
    • Shi HS, Li D, Zhang J, et al. Silencing of pkm2 increases the efficacy of docetaxel in human lung cancer xenografts in mice. Cancer Sci. 2010;101:1447-1453.
    • (2010) Cancer Sci , vol.101 , pp. 1447-1453
    • Shi, H.S.1    Li, D.2    Zhang, J.3
  • 36
    • 0001160175 scopus 로고    scopus 로고
    • In vitro and in vivo targeting of immunoliposomal doxorubicin to human B-cell lymphoma
    • Lopes de Menezes DE, Pilarski LM, Allen TM. In vitro and in vivo targeting of immunoliposomal doxorubicin to human B-cell lymphoma. Cancer Res. 1998;58:3320-3330.
    • (1998) Cancer Res , vol.58 , pp. 3320-3330
    • Lopes de Menezes, D.E.1    Pilarski, L.M.2    Allen, T.M.3
  • 39
  • 40
    • 0029045184 scopus 로고
    • Dose-intensive chemotherapy with cisplatin, vincristine, doxorubicin and etoposide against lung cancer: A pilot study
    • Yanagawa H, Bando H, Takishita Y. Dose-intensive chemotherapy with cisplatin, vincristine, doxorubicin and etoposide against lung cancer: a pilot study. Anticancer Res. 1995;15:613-616.
    • (1995) Anticancer Res , vol.15 , pp. 613-616
    • Yanagawa, H.1    Bando, H.2    Takishita, Y.3
  • 41
    • 19544380093 scopus 로고    scopus 로고
    • Design, synthesis and biologi-cal evaluation of heteroaryl diketohexenoic and diketobutanoic acids as HIV-1 integrase inhibitors endowed with antiretroviral activity
    • Di Santo R, Costi R, Artico M, et al. Design, synthesis and biologi-cal evaluation of heteroaryl diketohexenoic and diketobutanoic acids as HIV-1 integrase inhibitors endowed with antiretroviral activity. Farmaco. 2005;60:409-417.
    • (2005) Farmaco , vol.60 , pp. 409-417
    • Di Santo, R.1    Costi, R.2    Artico, M.3
  • 42
    • 84873602235 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of new heteroaryl carboxylic acid derivatives as anti-inflammatory-analgesic agents
    • Abouzid KA, Khalil NA, Ahmed EM, Zaitone SA. Synthesis and biological evaluation of new heteroaryl carboxylic acid derivatives as anti-inflammatory-analgesic agents. Chem Pharm Bull (Tokyo). 2013;61:222-228.
    • (2013) Chem Pharm Bull (Tokyo) , vol.61 , pp. 222-228
    • Abouzid, K.A.1    Khalil, N.A.2    Ahmed, E.M.3    Zaitone, S.A.4
  • 43
    • 33750718770 scopus 로고    scopus 로고
    • Curcumin reverses the effects of chronic stress on behavior, the HPA axis, BDNF expression and phosphorylation of CREB
    • Xu Y, Ku B, Tie L, et al. Curcumin reverses the effects of chronic stress on behavior, the HPA axis, BDNF expression and phosphorylation of CREB. Brain Res. 2006;1122:56-64.
    • (2006) Brain Res , vol.1122 , pp. 56-64
    • Xu, Y.1    Ku, B.2    Tie, L.3
  • 44
    • 33244476761 scopus 로고    scopus 로고
    • Antiproliferation and apoptosis induced by curcumin in human ovarian cancer cells
    • Shi M, Cai Q, Yao L, Mao Y, Ming Y, Ouyang G. Antiproliferation and apoptosis induced by curcumin in human ovarian cancer cells. Cell Biol Int. 2006;30:221-226.
    • (2006) Cell Biol Int , vol.30 , pp. 221-226
    • Shi, M.1    Cai, Q.2    Yao, L.3    Mao, Y.4    Ming, Y.5    Ouyang, G.6
  • 45
    • 82755176687 scopus 로고    scopus 로고
    • Curcumin enhances the efficacy of chemotherapy by tailoring p65NFκB-p300 cross-talk in favor of p53-p300 in breast cancer
    • Sen GS, Mohanty S, Hossain DM, et al. Curcumin enhances the efficacy of chemotherapy by tailoring p65NFκB-p300 cross-talk in favor of p53-p300 in breast cancer. J Biol Chem. 2011;286:42232-42247.
    • (2011) J Biol Chem , vol.286 , pp. 42232-42247
    • Sen, G.S.1    Mohanty, S.2    Hossain, D.M.3


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