In vitro cytotoxicity assessment based on KC50 with real-time cell analyzer (RTCA) assay

Computational Biology and Chemistry

Volumn 47, Issue , 2013, Pages 113-120

  Pan, Tianhong ^a,b   Khare, Swanand ^b   Ackah, Fred ^c   Huang, Biao ^b   Zhang, Weiping ^c   Gabos, Stephan ^c   Jin, Can ^d   Stampfl, Melinda ^d  

^a JIANGSU UNIVERSITY   (China)

^b UNIVERSITY OF ALBERTA   (Canada)

^c Alberta Health   (Canada)

^d Department of Biology ACEA Biosciences ^*  (United States)

Author keywords

High throughput screening (HTS); In vitro cytotoxicity assessment; Regression analysis; Time dependent cellular response profile (TCRP)

Indexed keywords

CELL CULTURE; CELL DEATH; CELL GROWTH; DYNAMIC RESPONSE; GROWTH KINETICS; POPULATION STATISTICS; REGRESSION ANALYSIS; TOXICITY;

CELLULAR CHANGES; CELLULAR RESPONSE; CONCENTRATION-DEPENDENT; CYTOTOXICITY ASSESSMENT; HIGH-THROUGHPUT SCREENING; IN-VITRO; TECHNOLOGICAL ADVANCES; TOXICOLOGY TESTS;

CYTOTOXICITY;

ARTICLE; CELL DEATH; CELL LINE; DOSE RESPONSE; DRUG EFFECT; HIGH THROUGHPUT SCREENING; HIGH-THROUGHPUT SCREENING (HTS); HUMAN; IN VITRO CYTOTOXICITY ASSESSMENT; LD 50; REGRESSION ANALYSIS; STRUCTURE ACTIVITY RELATION; TIME; TIME-DEPENDENT CELLULAR RESPONSE PROFILE (TCRP);

HIGH-THROUGHPUT SCREENING (HTS); IN VITRO CYTOTOXICITY ASSESSMENT; REGRESSION ANALYSIS; TIME-DEPENDENT CELLULAR RESPONSE PROFILE (TCRP);

CELL DEATH; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; LETHAL DOSE 50; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS;

EID: 84884543587     PISSN: 14769271     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.compbiolchem.2013.08.008     Document Type: Article

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