The reticulin algorithm for adrenocortical tumor diagnosis a multicentric validation study on 245 unpublished cases

American Journal of Surgical Pathology

Volumn 37, Issue 9, 2013, Pages 1433-1440

  Duregon, Eleonora ^a   Fassina, Ambrogio ^c   Volante, Marco ^a   Nesi, Gabriella ^f   Santi, Raffaella ^f   Gatti, Gaia ^a   Cappellesso, Rocco ^c   Ciaramella, Paolo Dalino ^g   Ventura, Laura ^e   Gambacorta, Marcello ^g   Dei Tos, Angelo Paolo ^h   Loli, Paola ^c   Mannelli, Massimo ^f   Mantero, Franco ^d   Berruti, Alfredo ⁱ   Terzolo, Massimo ^b   Papotti, Mauro ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c Pathology and Cytopathology Unit   (Italy)

^d Endocrinology   (Italy)

^e UNIVERSITY OF PADOVA   (Italy)

^f UNIVERSITY OF FLORENCE   (Italy)

^g OSPEDALE NIGUARDA CA GRANDA   (Italy)

^h GENERAL HOSPITAL   (Italy)

ⁱ UNIVERSITY OF BRESCIA   (Italy)

Author keywords

Adrenal cortex; Carcinoma; Diagnosis; Reproducibility study; Reticulin stain

Indexed keywords

RETICULIN; TUMOR MARKER;

ADOLESCENT; ADRENAL CORTEX ADENOMA; ADRENAL CORTEX CARCINOMA; ADRENAL CORTEX TUMOR; ADULT; AGED; ALGORITHM; ARTICLE; CHEMISTRY; CHILD; FEMALE; HUMAN; INFANT; ITALY; MALE; METHODOLOGY; MIDDLE AGED; MULTICENTER STUDY; OBSERVER VARIATION; PATHOLOGY; PREDICTIVE VALUE; PRESCHOOL CHILD; PROGNOSIS; REPRODUCIBILITY; STAINING; VALIDATION STUDY; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADRENAL CORTEX NEOPLASMS; ADRENOCORTICAL ADENOMA; ADRENOCORTICAL CARCINOMA; ADULT; AGED; AGED, 80 AND OVER; ALGORITHMS; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; ITALY; MALE; MIDDLE AGED; OBSERVER VARIATION; PREDICTIVE VALUE OF TESTS; PROGNOSIS; REPRODUCIBILITY OF RESULTS; RETICULIN; STAINING AND LABELING; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 84884531916     PISSN: 01475185     EISSN: 15320979     Source Type: Journal    
DOI: 10.1097/PAS.0b013e31828d387b     Document Type: Article

References (21)

1. Hough AJ, Hollifield JW, Page DL, et al. Prognostic factors in adrenal cortical tumors. A mathematical analysis of clinical and morphologic data. Am J Clin Pathol. 1979;72:390-399.
2. van't Sant HP, Bouvy ND, Kazemier G, et al. The prognostic value of two different histopathological scoring systems for adrenocortical carcinomas. Histopathology. 2007;51:239-245.
3. Weiss LM. Comparative histologic study of 43 metastasizing and nonmetastasizing adrenocortical tumors. Am J Surg Pathol. 1984;8: 163-169.
4. Weiss LM, Medeiros LJ, Vickery AL Jr. Pathologic features of prognostic significance in adrenocortical carcinoma. Am J Surg Pathol. 1989;13:202-206.
5. Lau SK, Weiss LM. The Weiss system for evaluating adrenocortical neoplasms: 25 years later. Hum Pathol. 2009;40:757-768.
6. Tissier F, Aubert S, Leteurtre E, et al. Adrenocortical tumors: improving the practice of the Weiss system through virtual microscopy: a National Program of the French Network INCa-COMETE. Am J Surg Pathol. 2012;36:1194-1201.
7. Aubert S, Wacrenier A, Leroy X, et al. Weiss system revisited: a clinicopathologic and immunohistochemical study of 49 adrenocortical tumors. Am J Surg Pathol. 2002;26:1612-1619.
8. Blanes A, Diaz-Cano SJ. Histologic criteria for adrenocortical proliferative lesions: value of mitotic figure variability. Am J Clin Pathol. 2007;127:398-408.
9. Bisceglia M, Ludovico O, Di Mattia A, et al. Adrenocortical oncocytic tumors: report of 10 cases and review of the literature. Int J Surg Pathol. 2004;12:231-243.
10. Papotti M, Volante M, Duregon E, et al. Adrenocortical tumors with myxoid features: a distinct morphologic and phenotypical variant exhibiting malignant behavior. Am J Surg Pathol. 2010; 34:973-983.
11. Volante M, Bollito E, Sperone P, et al. Clinicopathological study of a series of 92 adrenocortical carcinomas: from a proposal of simplified diagnostic algorithm to prognostic stratification. Histopathology. 2009;55:535-543.
12. Duregon E, Volante M, Cappia S, et al. Oncocytic adrenocortical tumors: diagnostic algorithm and mitochondrial DNA profile in 27 cases. Am J Surg Pathol. 2011;35:1882-1893.
13. Sanad S. Histopathological and immunohistochemical studies on the adrenal cortical tumors of Egyptian patients. Life Sci J. 2011;8:970-978.
14. de Krijger RR, Papathomas TG. Adrenocortical neoplasia: evolving concepts in tumorigenesis with an emphasis on adrenal cortical carcinoma variants. Virchows Arch. 2012;460:9-18.
15. Wieneke JA, Thompson LD, Heffess CS. Adrenal cortical neoplasms in the pediatric population: a clinicopathologic and immunophenotypic analysis of 83 patients. Am J Surg Pathol. 2003;27:867-881.
16. Horvath E. Pituitary hyperplasia. Pathol Res Pract. 1988;183:623-625.
17. Papotti M, Volante M, Bussolati G. Applied histochemistry in disorders of the endocrine system. In: Wick MR, ed. Diagnostic Histochemistry. University of Virginia, Charlottesville: Cambridge University Press; 2008.
18. Ambrosini-Spaltro A, Eusebi V. Meningeal hemangiopericytomas and hemangiopericytoma/solitary fibrous tumors of extracranial soft tissues: a comparison. Virchows Arch. 2010;456:343-354.
19. Bernard MH, Sidhu S, Berger N, et al. A case report in favor of a multistep adrenocortical tumorigenesis. J Clin Endocrinol Metab. 2003;88:998-1001.
20. Volante M, Buttigliero C, Greco E, et al. Pathological and molecular features of adrenocortical carcinoma: an update. J Clin Pathol. 2008;61:787-793.
21. Papotti M, Libe R, Duregon E, et al. The Weiss score and beyond-histopathology for adrenocortical carcinoma. Horm Cancer. 2011;2:333-340.