-
1
-
-
0032104245
-
The extended protein kinase C superfamily
-
Mellor H Parker PJ. The extended protein kinase C superfamily. Biochem J 1998; 332: 281-292.
-
(1998)
Biochem J
, vol.332
, pp. 281-292
-
-
Mellor, H.1
Parker, P.J.2
-
2
-
-
20044363128
-
Survival role of protein kinase C (PKC) in chronic lymphocytic leukemia and determination of isoform expression pattern and genes altered by PKC inhibition
-
Alkan S, Huang Q, Ergin M, et al. Survival role of protein kinase C (PKC) in chronic lymphocytic leukemia and determination of isoform expression pattern and genes altered by PKC inhibition. Am J Hematol 2005; 79: 97-106.
-
(2005)
Am J Hematol
, vol.79
, pp. 97-106
-
-
Alkan, S.1
Huang, Q.2
Ergin, M.3
-
3
-
-
33845458053
-
Regulation of Akt/PKB by phosphatidylinositol 3-kinase-dependent and -independent pathways in B-cell chronic lymphocytic leukemia cells: Role of protein kinase C{beta}
-
Barragan M, de Frias M, Iglesias-Serret D, et al. Regulation of Akt/PKB by phosphatidylinositol 3-kinase-dependent and -independent pathways in B-cell chronic lymphocytic leukemia cells: Role of protein kinase C{beta}. J Leukoc Biol 2006; 80: 1473-1479.
-
(2006)
J Leukoc Biol
, vol.80
, pp. 1473-1479
-
-
Barragan, M.1
De Frias, M.2
Iglesias-Serret, D.3
-
4
-
-
84879417048
-
Protein kinase C expression is deregulated in chronic lymphocytic leukemia
-
Kabir NN, Rönnstrand L, Kazi JU. Protein kinase C expression is deregulated in chronic lymphocytic leukemia. Leuk Lymphoma 2013; 54: 2288-2290.
-
(2013)
Leuk Lymphoma
, vol.54
, pp. 2288-2290
-
-
Kabir, N.N.1
Rönnstrand, L.2
Kazi, J.U.3
-
5
-
-
33846883742
-
B-cell receptor signaling in chronic lymphocytic leukemia cells is regulated by overexpressed active protein kinase CbetaII
-
Abrams ST, Lakum T, Lin K, et al. B-cell receptor signaling in chronic lymphocytic leukemia cells is regulated by overexpressed active protein kinase CbetaII. Blood 2007; 109: 1193-1201.
-
(2007)
Blood
, vol.109
, pp. 1193-1201
-
-
Abrams, S.T.1
Lakum, T.2
Lin, K.3
-
6
-
-
0037111661
-
Constitutively activated phosphatidylinositol-3 kinase (PI-3K) is involved in the defect of apoptosis in B-CLL: Association with protein kinase Cdelta
-
Ringshausen I, Schneller F, Bogner C, et al. Constitutively activated phosphatidylinositol-3 kinase (PI-3K) is involved in the defect of apoptosis in B-CLL: Association with protein kinase Cdelta. Blood 2002; 100: 3741-3748.
-
(2002)
Blood
, vol.100
, pp. 3741-3748
-
-
Ringshausen, I.1
Schneller, F.2
Bogner, C.3
-
7
-
-
33845198717
-
CD5 provides viability signals to B cells from a subset of B-CLL patients by a mechanism that involves PKC
-
Perez-Chacon G, Vargas JA, Jorda J, et al. CD5 provides viability signals to B cells from a subset of B-CLL patients by a mechanism that involves PKC. Leuk Res 2007; 31: 183-193.
-
(2007)
Leuk Res
, vol.31
, pp. 183-193
-
-
Perez-Chacon, G.1
Vargas, J.A.2
Jorda, J.3
-
8
-
-
77649207387
-
N OTCH2 links protein kinase C delta to the expression of CD23 in chronic lymphocytic leukaemia (CLL) cells
-
Hubmann R, Duchler M, Schnabl S, et al. N OTCH2 links protein kinase C delta to the expression of CD23 in chronic lymphocytic leukaemia (CLL) cells. Br J Haematol 2010; 148: 868-878.
-
(2010)
Br J Haematol
, vol.148
, pp. 868-878
-
-
Hubmann, R.1
Duchler, M.2
Schnabl, S.3
-
9
-
-
74249107839
-
Recruitment of PKC-betaII to lipid rafts mediates apoptosis-resistance in chronic lymphocytic leukemia expressing ZAP-70
-
zum Buschenfelde CM, Wagner M, Lutzny G, et al. Recruitment of PKC-betaII to lipid rafts mediates apoptosis-resistance in chronic lymphocytic leukemia expressing ZAP-70. Leukemia 2010; 24: 141-152.
-
(2010)
Leukemia
, vol.24
, pp. 141-152
-
-
Zum Buschenfelde, C.M.1
Wagner, M.2
Lutzny, G.3
-
10
-
-
84872387409
-
Protein kinase C-beta-dependent activation of NF-kappaB in stromal cells is indispensable for the survival of chronic lymphocytic leukemia B cells in vivo
-
Lutzny G, Kocher T, Schmidt-Supprian M, et al. Protein kinase C-beta-dependent activation of NF-kappaB in stromal cells is indispensable for the survival of chronic lymphocytic leukemia B cells in vivo. Cancer Cell 2013; 23: 77-92.
-
(2013)
Cancer Cell
, vol.23
, pp. 77-92
-
-
Lutzny, G.1
Kocher, T.2
Schmidt-Supprian, M.3
-
11
-
-
79953655788
-
CAL-101, an isoform-selective inhibitor of phosphatidylinositol 3-kinase P110{delta}, demonstrates clinical activity and pharmacodynamic effects in patients with relapsed or refractory chronic lymphocytic leukemia
-
Abstract 55
-
Furman RR, Byrd JC, Brown JR, et al. CAL-101, an isoform-selective inhibitor of phosphatidylinositol 3-kinase P110{delta}, demonstrates clinical activity and pharmacodynamic effects in patients with relapsed or refractory chronic lymphocytic leukemia. Blood 2010; 116(Suppl. 1): Abstract 55.
-
(2010)
Blood
, vol.116
, Issue.SUPPL. 1
-
-
Furman, R.R.1
Byrd, J.C.2
Brown, J.R.3
-
12
-
-
78951472301
-
The Bruton's tyrosine kinase inhibitor, PCI- 32765, is well tolerated and demonstrates promising clinical activity in chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL): An update on ongoing phase 1 studies
-
Abstract 57
-
Burger JA, O'B rien S, Fowler N, et al. The Bruton's tyrosine kinase inhibitor, PCI- 32765, is well tolerated and demonstrates promising clinical activity in chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL): An update on ongoing phase 1 studies. Blood 2010; 116(Suppl. 1): Abstract 57.
-
(2010)
Blood
, vol.116
, Issue.SUPPL. 1
-
-
Burger, J.A.1
O'Brien, S.2
Fowler, N.3
-
13
-
-
0034986264
-
UCN-01 induces cytotoxicity toward human CLL cells through a p53-independent mechanism
-
Byrd JC, Shinn C, Willis CR, et al. UCN-01 induces cytotoxicity toward human CLL cells through a p53-independent mechanism. Exp Hematol 2001; 29: 703-708.
-
(2001)
Exp Hematol
, vol.29
, pp. 703-708
-
-
Byrd, J.C.1
Shinn, C.2
Willis, C.R.3
-
14
-
-
0036175273
-
Actions of the selective protein kinase C inhibitor PKC412 on B-chronic lymphocytic leukemia cells in vitro
-
Ganeshaguru K, Wickremasinghe RG, Jones DT, et al. Actions of the selective protein kinase C inhibitor PKC412 on B-chronic lymphocytic leukemia cells in vitro. Haematologica 2002; 87: 167-176.
-
(2002)
Haematologica
, vol.87
, pp. 167-176
-
-
Ganeshaguru, K.1
Wickremasinghe, R.G.2
Jones, D.T.3
-
15
-
-
0037034928
-
Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine)
-
Sato S, Fujita N, Tsuruo T. Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine). Oncogene 2002; 21: 1727-1738.
-
(2002)
Oncogene
, vol.21
, pp. 1727-1738
-
-
Sato, S.1
Fujita, N.2
Tsuruo, T.3
-
16
-
-
0036045471
-
A novel treatment approach for low grade lymphoproliferative disorders using PKC412 (CGP41251), an inhibitor of protein kinase C
-
Virchis A, Ganeshaguru K, Hart S, et al. A novel treatment approach for low grade lymphoproliferative disorders using PKC412 (CGP41251), an inhibitor of protein kinase C. Hematol J 2002; 3: 131-136.
-
(2002)
Hematol J
, vol.3
, pp. 131-136
-
-
Virchis, A.1
Ganeshaguru, K.2
Hart, S.3
-
17
-
-
0035055595
-
Mechanisms of action of fl avopiridol
-
Sedlacek HH. Mechanisms of action of fl avopiridol. Crit Rev Oncol Hematol 2001; 38: 139-170.
-
(2001)
Crit Rev Oncol Hematol
, vol.38
, pp. 139-170
-
-
Sedlacek, H.H.1
-
18
-
-
33644536722
-
Mechanisms of apoptosis-induction by rottlerin: Therapeutic implications for B-CLL
-
Ringshausen I, Oelsner M, Weick K, et al. Mechanisms of apoptosis-induction by rottlerin: Therapeutic implications for B-CLL. Leukemia 2006; 20: 514-520.
-
(2006)
Leukemia
, vol.20
, pp. 514-520
-
-
Ringshausen, I.1
Oelsner, M.2
Weick, K.3
-
19
-
-
79960348240
-
Enzastaurin in patients with non-Hodgkin lymphomas: A multicenter, open-label, screening study
-
Abstract 3719
-
Forsyth CJ, Gomez D, Eliadis P, et al. Enzastaurin in patients with non-Hodgkin lymphomas: A multicenter, open-label, screening study. Blood 2009; 114(Suppl. 1): Abstract 3719.
-
(2009)
Blood
, vol.114
, Issue.SUPPL. 1
-
-
Forsyth, C.J.1
Gomez, D.2
Eliadis, P.3
|