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Volumn 19, Issue 19, 2013, Pages 3384-3390

The role of recombinant human platelet-derived growth factor-BB (rhPDGF-BB) in orthopaedic bone repair and regeneration

Author keywords

Bone regeneration; Bone repair; Clinical application; Platelet derived growth factor; rhPDGF BB

Indexed keywords

BECAPLERMIN; CALCIUM PHOSPHATE; COLLAGEN; HETERODIMER; HOMODIMER; PLATELET DERIVED GROWTH FACTOR RECEPTOR; RECOMBINANT PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR BB; PLATELET-DERIVED GROWTH FACTOR BB;

EID: 84884481987     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/1381612811319190005     Document Type: Article
Times cited : (66)

References (51)
  • 1
    • 0023201982 scopus 로고
    • Biology of bone transplantation
    • Burchardt H. Biology of bone transplantation. Orthopedic Clinics North Am 1987; 18(2): 187-96.
    • (1987) Orthopedic Clinics North Am , vol.18 , Issue.2 , pp. 187-196
    • Burchardt, H.1
  • 2
    • 33645275218 scopus 로고    scopus 로고
    • Human osteoblast cells: Isolation, characterization, and growth on polymers for musculoskeletal tissue engineering
    • El-Amin SF, Botchwey E, Tuli R, et al. Human osteoblast cells: isolation, characterization, and growth on polymers for musculoskeletal tissue engineering. J Biomedical Materials Res Part A 2006; 76(3): 439-49.
    • (2006) J Biomedical Materials Res Part A , vol.76 , Issue.3 , pp. 439-449
    • El-Amin, S.F.1    Botchwey, E.2    Tuli, R.3
  • 7
    • 0037734246 scopus 로고    scopus 로고
    • Complications of iliac crest graft and bone grafting alternatives in foot and ankle surgery
    • Boone DW. Complications of iliac crest graft and bone grafting alternatives in foot and ankle surgery. Foot Ankle Clinics 2003; 8(1): 1-14.
    • (2003) Foot Ankle Clinics , vol.8 , Issue.1 , pp. 1-14
    • Boone, D.W.1
  • 11
    • 0028825919 scopus 로고
    • Complications associated with harvesting autogenous iliac bone graft
    • Fowler BL, Dall BE, Rowe DE. Complications associated with harvesting autogenous iliac bone graft. Am J Orthop (Belle Mead NJ) 1995; 24(12): 895-903.
    • (1995) Am J Orthop (Belle Mead NJ) , vol.24 , Issue.12 , pp. 895-903
    • Fowler, B.L.1    Dall, B.E.2    Rowe, D.E.3
  • 12
    • 15944394738 scopus 로고    scopus 로고
    • A review of morbidity associated with bone harvest from the proximal tibial metaphysis
    • Frohberg U, Mazock JB. A review of morbidity associated with bone harvest from the proximal tibial metaphysis. Mund-, Kieferund Gesichtschirurgie: MKG 2005; 9(2): 63-5.
    • (2005) Mund-, Kieferund Gesichtschirurgie: MKG , vol.9 , Issue.2 , pp. 63-65
    • Frohberg, U.1    Mazock, J.B.2
  • 15
    • 0029852120 scopus 로고    scopus 로고
    • Superior gluteal artery injury during iliac bone grafting for spinal fusion. A case report and literature review
    • Lim EV, Lavadia WT, Roberts JM. Superior gluteal artery injury during iliac bone grafting for spinal fusion. A case report and literature review. Spine 1996; 21(20): 2376-8.
    • (1996) Spine , vol.21 , Issue.20 , pp. 2376-2378
    • Lim, E.V.1    Lavadia, W.T.2    Roberts, J.M.3
  • 16
  • 17
    • 0036599845 scopus 로고    scopus 로고
    • The role of growth factors in the repair of bone. Biology and clinical applications
    • Lieberman JR, Daluiski A, Einhorn TA. The role of growth factors in the repair of bone. Biology and clinical applications. J Bone Joint Surgery Am Vol 2002; 84-A(6): 1032-44.
    • (2002) J Bone Joint Surgery Am Vol , vol.84 A , Issue.6 , pp. 1032-1044
    • Lieberman, J.R.1    Daluiski, A.2    Einhorn, T.A.3
  • 18
    • 84893026707 scopus 로고    scopus 로고
    • Tissue engineering: Applications in oral and maxillofacial surgery and periodontics
    • Lynch SE. Tissue engineering: applications in oral and maxillofacial surgery and periodontics. Hanover Park, IL: Quintessence Pub.; 2008.
    • (2008) Hanover Park, IL: Quintessence Pub.
    • Lynch, S.E.1
  • 20
    • 84863286574 scopus 로고    scopus 로고
    • Recombinant human PDGF-BB in foot and ankle fusion
    • DiGiovanni CW, Lin S, Pinzur M. Recombinant human PDGF-BB in foot and ankle fusion. Exp Rev Med Devices 2012; 9(2): 111-22.
    • (2012) Exp Rev Med Devices , vol.9 , Issue.2 , pp. 111-122
    • DiGiovanni, C.W.1    Lin, S.2    Pinzur, M.3
  • 21
    • 44149090296 scopus 로고    scopus 로고
    • Role of platelet-derived growth factors in physiology and medicine
    • Andrae J, Gallini R, Betsholtz C. Role of platelet-derived growth factors in physiology and medicine. Genes Development 2008; 22(10): 1276-312.
    • (2008) Genes Development , vol.22 , Issue.10 , pp. 1276-1312
    • Andrae, J.1    Gallini, R.2    Betsholtz, C.3
  • 22
    • 2942687331 scopus 로고    scopus 로고
    • Platelet-derived growth factor--an introduction
    • Heldin CH. Platelet-derived growth factor--an introduction. Cytokine Growth Factor Rev 2004; 15(4): 195-6.
    • (2004) Cytokine Growth Factor Rev , vol.15 , Issue.4 , pp. 195-196
    • Heldin, C.H.1
  • 23
    • 0032875460 scopus 로고    scopus 로고
    • Mechanism of action and in vivo role of platelet-derived growth factor
    • Heldin CH, Westermark B. Mechanism of action and in vivo role of platelet-derived growth factor. Physiological Rev 1999; 79(4): 1283-316.
    • (1999) Physiological Rev , vol.79 , Issue.4 , pp. 1283-1316
    • Heldin, C.H.1    Westermark, B.2
  • 25
    • 0026875627 scopus 로고
    • Mitogenic, chemotactic, and synthetic responses of rat periodontal ligament fibroblastic cells to polypeptide growth factors in vitro
    • Matsuda N, Lin WL, Kumar NM, Cho MI, Genco RJ. Mitogenic, chemotactic, and synthetic responses of rat periodontal ligament fibroblastic cells to polypeptide growth factors in vitro. J Periodontol 1992; 63(6): 515-25.
    • (1992) J Periodontol , vol.63 , Issue.6 , pp. 515-525
    • Matsuda, N.1    Lin, W.L.2    Kumar, N.M.3    Cho, M.I.4    Genco, R.J.5
  • 27
    • 0030270961 scopus 로고    scopus 로고
    • Pericytes in the microvasculature
    • Hirschi KK, D'Amore PA. Pericytes in the microvasculature. Cardiovascular Res 1996; 32(4): 687-98.
    • (1996) Cardiovascular Res , vol.32 , Issue.4 , pp. 687-698
    • Hirschi, K.K.1    D'Amore, P.A.2
  • 28
    • 0025067429 scopus 로고
    • Purification of PDGF-AB and PDGF-BB from human platelet extracts and identification of all three PDGF dimers in human platelets
    • Hart CE, Bailey M, Curtis DA, et al. Purification of PDGF-AB and PDGF-BB from human platelet extracts and identification of all three PDGF dimers in human platelets. Biochemistry 1990; 29(1): 166-72.
    • (1990) Biochemistry , vol.29 , Issue.1 , pp. 166-172
    • Hart, C.E.1    Bailey, M.2    Curtis, D.A.3
  • 29
    • 0026586462 scopus 로고
    • Purification and analysis of proteinase-resistant mutants of recombinant platelet-derived growth factor-BB exhibiting improved biological activity
    • Cook AL, Kirwin PM, Craig S, et al. Purification and analysis of proteinase-resistant mutants of recombinant platelet-derived growth factor-BB exhibiting improved biological activity. Biochemical J 1992; 281 (Pt 1): 57-65.
    • (1992) Biochemical J , vol.281 , Issue.PART 1 , pp. 57-65
    • Cook, A.L.1    Kirwin, P.M.2    Craig, S.3
  • 30
    • 0035989750 scopus 로고    scopus 로고
    • Becaplermin: Recombinant platelet derived growth factor, a new treatment for healing diabetic foot ulcers
    • Nagai MK, Embil JM. Becaplermin: recombinant platelet derived growth factor, a new treatment for healing diabetic foot ulcers. Expert Opinion Biological Therapy 2002; 2(2): 211-8.
    • (2002) Expert Opinion Biological Therapy , vol.2 , Issue.2 , pp. 211-218
    • Nagai, M.K.1    Embil, J.M.2
  • 33
    • 84860389650 scopus 로고    scopus 로고
    • Correlation of growth factor levels at the fusion site of diabetic patients undergoing hindfoot arthrodesis and clinical outcome
    • Verma R, Koerner J, Breitbart E, et al. Correlation of growth factor levels at the fusion site of diabetic patients undergoing hindfoot arthrodesis and clinical outcome. Curr Orthopaedic Practice 2011; 22(3): 251-6.
    • (2011) Curr Orthopaedic Practice , vol.22 , Issue.3 , pp. 251-256
    • Verma, R.1    Koerner, J.2    Breitbart, E.3
  • 34
    • 0024725571 scopus 로고
    • A combination of platelet-derived and insulin-like growth factors enhances periodontal regeneration
    • Lynch SE, Williams RC, Polson AM, et al. A combination of platelet-derived and insulin-like growth factors enhances periodontal regeneration. J Clinical Periodontol 1989; 16(8): 545-8.
    • (1989) J Clinical Periodontol , vol.16 , Issue.8 , pp. 545-548
    • Lynch, S.E.1    Williams, R.C.2    Polson, A.M.3
  • 35
    • 0026328504 scopus 로고
    • Effects of the plateletderived growth factor/insulin-like growth factor-I combination on bone regeneration around titanium dental implants. Results of a pilot study in beagle dogs
    • Lynch SE, Buser D, Hernandez RA, et al. Effects of the plateletderived growth factor/insulin-like growth factor-I combination on bone regeneration around titanium dental implants. Results of a pilot study in beagle dogs. J Periodontol 1991; 62(11): 710-6.
    • (1991) J Periodontol , vol.62 , Issue.11 , pp. 710-716
    • Lynch, S.E.1    Buser, D.2    Hernandez, R.A.3
  • 36
    • 70249091188 scopus 로고    scopus 로고
    • Vertical ridge augmentation using an equine block infused with recombinant human platelet-derived growth factor-BB: A histologic study in a canine model
    • Simion M, Nevins M, Rocchietta I, et al. Vertical ridge augmentation using an equine block infused with recombinant human platelet-derived growth factor-BB: a histologic study in a canine model. Int J Periodontics Restorative Dentistry 2009; 29(3): 245-55.
    • (2009) Int J Periodontics Restorative Dentistry , vol.29 , Issue.3 , pp. 245-255
    • Simion, M.1    Nevins, M.2    Rocchietta, I.3
  • 37
    • 38049090640 scopus 로고    scopus 로고
    • Accelerated fracture healing in the geriatric, osteoporotic rat with recombinant human platelet-derived growth factor-BB and an injectable beta-tricalcium phosphate/collagen matrix
    • Hollinger JO, Onikepe AO, MacKrell J, et al. Accelerated fracture healing in the geriatric, osteoporotic rat with recombinant human platelet-derived growth factor-BB and an injectable beta-tricalcium phosphate/collagen matrix. J orthopaedic research: official publication Orthopaedic Res Soc 2008; 26(1): 83-90.
    • (2008) J orthopaedic research: Official publication Orthopaedic Res Soc , vol.26 , Issue.1 , pp. 83-90
    • Hollinger, J.O.1    Onikepe, A.O.2    McKrell, J.3
  • 38
    • 67749147120 scopus 로고    scopus 로고
    • Recombinant human platelet-derived growth factor BB (rhPDGF-BB) and betatricalcium phosphate/collagen matrix enhance fracture healing in a diabetic rat model
    • Al-Zube L, Breitbart EA, O'Connor JP, et al. Recombinant human platelet-derived growth factor BB (rhPDGF-BB) and betatricalcium phosphate/collagen matrix enhance fracture healing in a diabetic rat model. J orthopaedic research: official Publication Of The Orthopaedic Res Soc 2009; 27(8): 1074-81.
    • (2009) J orthopaedic research: Official Publication Of The Orthopaedic Res Soc , vol.27 , Issue.8 , pp. 1074-1081
    • Al-Zube, L.1    Breitbart, E.A.2    O'Connor, J.P.3
  • 39
    • 68349141959 scopus 로고    scopus 로고
    • Recombinant human platelet-derived growth factor-BB augmentation of new-bone formation in a rat model of distraction osteogenesis
    • Moore DC, Ehrlich MG, McAllister SC, et al. Recombinant human platelet-derived growth factor-BB augmentation of new-bone formation in a rat model of distraction osteogenesis. J Bone Joint Surgery Am Volume 2009; 91(8): 1973-84.
    • (2009) J Bone Joint Surgery Am Volume , vol.91 , Issue.8 , pp. 1973-1984
    • Moore, D.C.1    Ehrlich, M.G.2    McAllister, S.C.3
  • 40
    • 84860015003 scopus 로고    scopus 로고
    • Augment bone graft products compare favorably with autologous bone graft in an ovine model of lumbar interbody spine fusion
    • Solchaga LA, Hee CK, Aguiar DJ, et al. Augment bone graft products compare favorably with autologous bone graft in an ovine model of lumbar interbody spine fusion. Spine 2012; 37(8): E461-7.
    • (2012) Spine , vol.37 , Issue.8 , pp. 461-467
    • Solchaga, L.A.1    Hee, C.K.2    Aguiar, D.J.3
  • 41
    • 79851489640 scopus 로고    scopus 로고
    • Platelet-derived growth factor applications in periodontal and peri-implant bone regeneration
    • Kaigler D, Avila G, Wisner-Lynch L, et al. Platelet-derived growth factor applications in periodontal and peri-implant bone regeneration. Expert Opinion Biological Therapy 2011; 11(3): 375-85.
    • (2011) Expert Opinion Biological Therapy , vol.11 , Issue.3 , pp. 375-385
    • Kaigler, D.1    Avila, G.2    Wisner-Lynch, L.3
  • 42
    • 84858117233 scopus 로고    scopus 로고
    • Growth factors and craniofacial surgery
    • Epub 2012/02/18
    • Alvarez P, Hee CK, Solchaga L, et al. Growth factors and craniofacial surgery. The J craniofacial surgery 2012; 23(1): 20-9. Epub 2012/02/18.
    • (2012) The J craniofacial surgery , vol.23 , Issue.1 , pp. 20-29
    • Alvarez, P.1    Hee, C.K.2    Solchaga, L.3
  • 43
    • 30944432610 scopus 로고    scopus 로고
    • Platelet-derived growth factor stimulates bone fill and rate of attachment level gain: Results of a large multicenter randomized controlled trial
    • Nevins M, Giannobile WV, McGuire MK, et al. Platelet-derived growth factor stimulates bone fill and rate of attachment level gain: results of a large multicenter randomized controlled trial. J Periodontol 2005; 76(12): 2205-15.
    • (2005) J Periodontol , vol.76 , Issue.12 , pp. 2205-2215
    • Nevins, M.1    Giannobile, W.V.2    McGuire, M.K.3
  • 44
    • 84893037626 scopus 로고    scopus 로고
    • PDGF Promotes Periodontal Regeneration in Localized Osseous Defects: 36 Month Extension Results from a Randomized, Controlled, Double-masked Clinical Trial
    • Nevins M, Kao RT, McGuire MK, et al. PDGF Promotes Periodontal Regeneration in Localized Osseous Defects: 36 Month Extension Results from a Randomized, Controlled, Double-masked Clinical Trial. J Periodontol 2012.
    • (2012) J Periodontol
    • Nevins, M.1    Kao, R.T.2    McGuire, M.K.3
  • 47
    • 84893144261 scopus 로고    scopus 로고
    • Recombinant Human Platelet-Derived Growth Factor-BB and Beta-Tricalcium Phosphate (rhPDGF-BB / β-TCP): A New Alternative to the use of Autogenous Bone Graft in Promoting Bone Regeneration
    • in press
    • DiGiovanni CW, Lin S, Baumhauer JF, et al. Recombinant Human Platelet-Derived Growth Factor-BB and Beta-Tricalcium Phosphate (rhPDGF-BB / β-TCP): A New Alternative to the use of Autogenous Bone Graft in Promoting Bone Regeneration. J Bone Joint Surgery Am Volume. in press.
    • J Bone Joint Surgery Am Volume.
    • DiGiovanni, C.W.1    Lin, S.2    Baumhauer, J.F.3
  • 48
    • 80052553409 scopus 로고    scopus 로고
    • Augmentation of a rotator cuff suture repair using rhPDGF-BB and a type I bovine collagen matrix in an ovine model
    • Hee CK, Dines JS, Dines DM, et al. Augmentation of a rotator cuff suture repair using rhPDGF-BB and a type I bovine collagen matrix in an ovine model. American J Sports Med 2011; 39(8): 1630-9.
    • (2011) American J Sports Med , vol.39 , Issue.8 , pp. 1630-1639
    • Hee, C.K.1    Dines, J.S.2    Dines, D.M.3
  • 49
    • 84884477054 scopus 로고    scopus 로고
    • Effect of recombinant human platelet-derived growth factor-BB-coated sutures on Achilles tendon healing in a rat model: A histological and biomechanical study
    • Cummings SH, Grande DA, Hee CK, et al. Effect of recombinant human platelet-derived growth factor-BB-coated sutures on Achilles tendon healing in a rat model: A histological and biomechanical study. J Tissue Engineering 2012; 3(1): 2041731412453577.
    • (2012) J Tissue Engineering , vol.3 , Issue.1 , pp. 2041731412453577
    • Cummings, S.H.1    Grande, D.A.2    Hee, C.K.3
  • 50
    • 84861804831 scopus 로고    scopus 로고
    • Regenerative tendon and ligament healing: Opportunities with recombinant human platelet-derived growth factor BB-homodimer
    • Hee CK, Dines JS, Solchaga LA, Shah VR, Hollinger JO. Regenerative tendon and ligament healing: opportunities with recombinant human platelet-derived growth factor BB-homodimer. Tissue engineering Part B, Rev 2012; 18(3): 225-34.
    • (2012) Tissue engineering Part B, Rev , vol.18 , Issue.3 , pp. 225-234
    • Hee, C.K.1    Dines, J.S.2    Solchaga, L.A.3    Shah, V.R.4    Hollinger, J.O.5
  • 51
    • 84893155259 scopus 로고    scopus 로고
    • Dose-response effect of an intra-tendon application of recombinant human platelet-derived growth factor-BB (rhPDGF-BB) in a rat Achilles tendinopathy model
    • Shah V, Bendele A, Dines JS, et al. Dose-response effect of an intra-tendon application of recombinant human platelet-derived growth factor-BB (rhPDGF-BB) in a rat Achilles tendinopathy model. J orthopaedic research: official publication Orthopaedic Res Soc 2012.
    • (2012) J orthopaedic research: Official publication Orthopaedic Res Soc
    • Shah, V.1    Bendele, A.2    Dines, J.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.