Genome sequencing for healthy individuals

Trends in Genetics

Volumn 29, Issue 10, 2013, Pages 556-558

  Sanderson, Saskia C ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BEHAVIOR CHANGE; EMOTION; GENE SEQUENCE; GENETIC COUNSELING; GENETIC RISK; HEALTH BEHAVIOR; HEALTH CARE PERSONNEL; HUMAN; HUMAN GENOME; INCIDENTAL FINDING; NOTE; PATIENT EDUCATION; PHARMACOGENOMICS; PHENOTYPE; PRIORITY JOURNAL; PROPHYLAXIS; SINGLE NUCLEOTIDE POLYMORPHISM; WELLBEING;

BEHAVIOR; GENOME, HUMAN; HEALTH; HEALTH SERVICES ACCESSIBILITY; HEALTHY VOLUNTEERS; HUMANS; SEQUENCE ANALYSIS, DNA;

EID: 84884416869     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tig.2013.08.005     Document Type: Note

References (15)

1. Chen R., et al. Personal omics profiling reveals dynamic molecular and medical phenotypes. Cell 2012, 148:1293-1307.
2. Patel C.J., et al. Whole genome sequencing in support of wellness and health maintenance. Genome Med. 2013, 5:58.
3. Angrist M. Eyes wide open: the personal genome project, citizen science and veracity in informed consent. Pers. Med. 2009, 6:691-699.
4. Burn J. Should we sequence everyone's genome? Yes. BMJ 2013, 346:3133.
5. Brunham L.R., Hayden M.R. Whole-genome sequencing: the new standard of care?. Science 2012, 336:1112-1113.
6. Flinter F. Should we sequence everyone's genome? No. BMJ 2013, 346:3132.
7. Ormond K.E., et al. Challenges in the clinical application of whole-genome sequencing. Lancet 2010, 375:1749-1751.
8. Evans J.P., et al. We screen newborns, don't we? Realizing the promise of public health genomics. Genet. Med. 2013, 15:332-334.
9. Cassa C.A., et al. Disclosing pathogenic genetic variants to research participants: quantifying an emerging ethical responsibility. Genome Res. 2012, 22:421-428.
10. Schadt E.E. The changing privacy landscape in the era of big data. Mol. Syst. Biol. 2012, 8:612.
11. Green R.C., et al. ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing. Genet. Med. 2013, 15:565-574.
12. Biesecker L.G. Opportunities and challenges for the integration of massively parallel genomic sequencing into clinical practice: lessons from the ClinSeq project. Genet. Med. 2012, 14:393-398.
13. Yu J.H., et al. Self-guided management of exome and whole-genome sequencing results: changing the results return model. Genet. Med. 2013.
14. Marteau T.M., et al. Effects of communicating DNA-based disease risk estimates on risk-reducing behaviours. Cochrane Database Syst. Rev. 2010, 10:CD007275.
15. Bloss C.S., et al. Effect of direct-to-consumer genomewide profiling to assess disease risk. N. Engl. J. Med. 2011, 364:524-534.