FoxO regulates expression of ABCA6, an intracellular ATP-binding-cassette transporter responsive to cholesterol

International Journal of Biochemistry and Cell Biology

Volumn 45, Issue 11, 2013, Pages 2651-2659

  Gai, Junfang ^a   Ji, Meiling ^a   Shi, Chenxi ^a   Li, Wenli ^a   Chen, Simin ^a   Wang, Yeyu ^a   Li, Hao ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

ABC transporters; Cholesterol; Endothelial cells; Forkhead box protein

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER A6; CHOLESTEROL; PHOSPHATIDYLINOSITOL 3 KINASE; SOMATOMEDIN C; TRANSCRIPTION FACTOR FOXO; UNCLASSIFIED DRUG; ABCA6 PROTEIN, HUMAN; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, HUMAN; FOXO3 PROTEIN, HUMAN; HYBRID PROTEIN; PROTEIN BINDING;

ARTICLE; CELL COMPARTMENTALIZATION; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME INACTIVATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; INTRACELLULAR MEMBRANE; LIPID TRANSPORT; MOLECULAR CLONING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; TRANSCRIPTION REGULATION; UMBILICAL VEIN ENDOTHELIAL CELL; ANIMAL; BINDING SITE; CELL FRACTIONATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; INTRACELLULAR SPACE; METABOLISM; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BASE SEQUENCE; BINDING SITES; CHOLESTEROL; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTRACELLULAR SPACE; MICE; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; SUBCELLULAR FRACTIONS;

EID: 84884406184     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2013.08.020     Document Type: Article

References (28)

1. M. Akiyama, Y. Sugiyama-Nakagiri, K. Sakai, J.R. McMillan, M. Goto, and K. Arita Mutations in lipid transporter ABCA12 in harlequin ichthyosis and functional recovery by corrective gene transfer J Clin Invest 115 2005 1777 1784 (Pubitemid 40979716)
2. T. Annilo, Z.Q. Chen, S. Shulenin, and M. Dean Evolutionary analysis of a cluster of ATP-binding cassette (ABC) genes Mamm Genome 14 2003 7 20 (Pubitemid 36132582)
3. A. Barthel, D. Schmoll, K.D. Kruger, R.A. Roth, and H.G. Joost Regulation of the forkhead transcription factor FKHR (FOXO1a) by glucose starvation and AICAR, an activator of AMP-activated protein kinase Endocrinology 143 2002 3183 3186 (Pubitemid 34809893)
4. S. Chen, J. Gai, Y. Wang, and H. Li FoxO regulates expression of decidual protein induced by progesterone (DEPP) in human endothelial cells FEBS Lett 585 2011 1796 1800
5. K.L. Clark, E.D. Halay, E. Lai, and S.K. Burley Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5 Nature 364 1993 412 420 (Pubitemid 23263212)
6. M. Dean, and T. Annilo Evolution of the ATP-binding cassette (ABC) transporter superfamily in vertebrates Annu Rev Genomics Hum Genet 6 2005 123 142 (Pubitemid 41397078)
7. K.E. Ile, W. Davis Jr., J.T. Boyd, A.M. Soulika, and K.D. Tew Identification of a novel first exon of the human ABCA2 transporter gene encoding a unique N-terminus Biochim Biophys Acta 1678 2004 22 32 (Pubitemid 38456945)
8. W.E. Kaminski, A. Piehler, and J.J. Wenzel ABC A-subfamily transporters: structure, function and disease Biochim Biophys Acta 1762 2006 510 524
9. W.E. Kaminski, J.J. Wenzel, A. Piehler, T. Langmann, and G. Schmitz ABCA6, a novel a subclass ABC transporter Biochem Biophys Res Commun 285 2001 1295 1301 (Pubitemid 32912924)
10. I. Klein, B. Sarkadi, and A. Varadi An inventory of the human ABC proteins Biochim Biophys Acta 1461 1999 237 262
11. J. Klucken, C. Buchler, E. Orso, W.E. Kaminski, M. Porsch-Ozcurumez, and G. Liebisch ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport Proc Natl Acad Sci U S A 97 2000 817 822 (Pubitemid 30070393)
12. Y. Kubo, S. Sekiya, M. Ohigashi, C. Takenaka, K. Tamura, and S. Nada ABCA5 resides in lysosomes, and ABCA5 knockout mice develop lysosomal disease-like symptoms Mol Cell Biol 25 2005 4138 4149 (Pubitemid 40617660)
13. P. Linsel-Nitschke, A.W. Jehle, J. Shan, G. Cao, D. Bacic, and D. Lan Potential role of ABCA7 in cellular lipid efflux to apoA-I J Lipid Res 46 2005 86 92 (Pubitemid 40066674)
14. M.F. Luciani, and G. Chimini The ATP binding cassette transporter ABC1, is required for the engulfment of corpses generated by apoptotic cell death EMBO J 15 1996 226 235 (Pubitemid 26029202)
15. S. Mukherjee, X. Zha, I. Tabas, and F.R. Maxfield Cholesterol distribution in living cells: fluorescence imaging using dehydroergosterol as a fluorescent cholesterol analog Biophys J 75 1998 1915 1925 (Pubitemid 28455186)
16. S. Ohtsuki, M. Kamoi, Y. Watanabe, H. Suzuki, S. Hori, and T. Terasaki Correlation of induction of ATP binding cassette transporter A5 (ABCA5) and ABCB1 mRNAs with differentiation state of human colon tumor Biol Pharm Bull 30 2007 1144 1146 (Pubitemid 46883871)
17. F. Petry, V. Ritz, C. Meineke, P. Middel, T. Kietzmann, and C. Schmitz-Salue Subcellular localization of rat Abca5, a rat ATP-binding-cassette transporter expressed in Leydig cells, and characterization of its splice variant apparently encoding a half-transporter Biochem J 393 2006 79 87 (Pubitemid 43049304)
18. A. Piehler, W.E. Kaminski, J.J. Wenzel, T. Langmann, and G. Schmitz Molecular structure of a novel cholesterol-responsive A subclass ABC transporter, ABCA9 Biochem Biophys Res Commun 295 2002 408 416 (Pubitemid 34785850)
19. S. Pierrou, M. Hellqvist, L. Samuelsson, S. Enerback, and P. Carlsson Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending EMBO J 13 1994 5002 5012 (Pubitemid 24319383)
20. M. Potente, C. Urbich, K. Sasaki, W.K. Hofmann, C. Heeschen, and A. Aicher Involvement of Foxo transcription factors in angiogenesis and postnatal neovascularization J Clin Invest 115 2005 2382 2392 (Pubitemid 41266200)
21. S. Ramaswamy, N. Nakamura, I. Sansal, L. Bergeron, and W.R. Sellers A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR Cancer Cell 2 2002 81 91 (Pubitemid 41043990)
22. D.A. Salih, and A. Brunet FoxO transcription factors in the maintenance of cellular homeostasis during aging Curr Opin Cell Biol 20 2008 126 136
23. S. Tsuruoka, K. Ishibashi, H. Yamamoto, M. Wakaumi, M. Suzuki, and G.J. Schwartz Functional analysis of ABCA8, a new drug transporter Biochem Biophys Res Commun 298 2002 41 45 (Pubitemid 35205384)
24. T.E. Weaver, C.L. Na, and M. Stahlman Biogenesis of lamellar bodies, lysosome-related organelles involved in storage and secretion of pulmonary surfactant Semin Cell Dev Biol 13 2002 263 270 (Pubitemid 35304511)
25. J.J. Wenzel, W.E. Kaminski, A. Piehler, S. Heimerl, T. Langmann, and G. Schmitz ABCA10, a novel cholesterol-regulated ABCA6-like ABC transporter Biochem Biophys Res Commun 306 2003 1089 1098 (Pubitemid 36776242)
26. Y.L. Woods, and G. Rena Effect of multiple phosphorylation events on the transcription factors FKHR, FKHRL1 and AFX Biochem Soc Trans 30 2002 391 397 (Pubitemid 35001563)
27. G. Yamano, H. Funahashi, O. Kawanami, L.X. Zhao, N. Ban, and Y. Uchida ABCA3 is a lamellar body membrane protein in human lung alveolar type II cells FEBS Lett 508 2001 221 225 (Pubitemid 33079249)
28. D. Ye, M. Hoekstra, R. Out, I. Meurs, J.K. Kruijt, and R.B. Hildebrand Hepatic cell-specific ATP-binding cassette (ABC) transporter profiling identifies putative novel candidates for lipid homeostasis in mice Atherosclerosis 196 2008 650 658