The current state of absence epilepsy: Can we have your attention?

Epilepsy Currents

Volumn 13, Issue 3, 2013, Pages 135-140

  Tenney, Jeffrey R ^a   Glauser, Tracy A ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; AMANTADINE; BENZODIAZEPINE DERIVATIVE; CALCIUM CHANNEL; ETHOSUXIMIDE; ETIRACETAM; LAMOTRIGINE; PHENOBARBITAL; VALPROIC ACID;

ABSENCE; CHILDHOOD ABSENCE EPILEPSY; CLINICAL FEATURE; COMORBIDITY; ELECTROENCEPHALOGRAPHY; GENERALIZED EPILEPSY; HUMAN; JEAVONS SYNDROME; KETOGENIC DIET; MONOTHERAPY; MORBIDITY; OUTCOME ASSESSMENT; PATHOPHYSIOLOGY; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL (TOPIC); REMISSION; REVIEW;

EID: 84884343337     PISSN: 15357597     EISSN: 15357511     Source Type: Journal    
DOI: 10.5698/1535-7511-13.3.135     Document Type: Review

References (74)

1. Adie WJ. Pyknolepsy: A form of epilepsy in children, with a good prognosis. Proc R Soc Med 1924;17(Neurol Sect):19-25.
2. Penry JK, Dreifuss FE. Automatisms associated with the absence of petit mal epilepsy. Arch Neurol 1969;21:142-149.
3. Panayiotopoulos CP. Typical absence seizures and related epileptic syndromes: Assessment of current state and directions for future research. Epilepsia 2008;49:2131-2139.
4. Frank LM, Enlow T, Holmes GL, Manasco P, Concannon S, Chen C, Womble G, Casale EJ. Lamictal (lamotrigine) monotherapy for typical absence seizures in children. Epilepsia 1999;40:973-979.
5. Holmes GL, McKeever M, Adamson M. Absence seizures in children: Clinical and electroencephalographic features. Ann Neurol 1987;12:268-273.
6. Glauser TA, Cnaan A, Shinnar S, Hirtz DG, Dlugos D, Masur D, Clark PO, Capparelli EV, Adamson PC. Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy. N Engl J Med 2010;362:790-799.
7. Sadleir LG, Farrell K, Smith S, Connolly MB, Scheffer IE. Electroclinical features of absence seizures in childhood absence epilepsy. Neurology 2006;67:413-418.
8. Loiseau P, Duche B, Pedespan JM. Absence epilepsies. Epilepsia 1995;36:1182-1186.
9. Loddenkemper TBS, Serratosa JM, Berkovic SF. Idiopathic generalized epilepsy syndromes of childhood and adolescence. In: The Treatment of Epilepsy. (Wyllie EGA, Lachhwani DK, eds) Philadelphia: Lippincott Williams & Wilkins, 2006:399-400.
10. Proposal for revised clinical and electroencephalographic classification of epileptic seizures. From the Commission on Classification and Terminology of the International League Against Epilepsy. Epilepsia 1981;22:489-501.
11. Epstein MA, Duchowny M, Jayakar P, Resnick TJ, Alvarez LA. Altered responsiveness during hyperventilation-induced EEG slowing: A nonepileptic phenomenon in normal children. Epilepsia 1994;35:1204-1207.
12. Berg AT, Berkovic SF, Brodie MJ, Buchhalter J, Cross JH, van Emde Boas W, Engel J, French J, Glauser TA, Mathern GW, Moshe SL, Nordli D, Plouin P, Scheffer IE. Revised terminology and concepts for organization of seizures and epilepsies: Report of the ILAE Commission on Classification and Terminology, 2005-2009. Epilepsia 2010;51:676-685.
13. Senbil N, Soyer O, Turanly G, Gurer YK. Fixation-off sensitivity and generalized epileptic EEG induced by eyes closed. Pediatr Neurol 2006;35:363-366.
14. Berg AT, Shinnar S, Levy SR, Testa FM, Smith-Rapaport S, Beckerman B. How well can epilepsy syndromes be identified at diagnosis? A reassessment 2 years after initial diagnosis. Epilepsia 2000;41:1269-1275.
15. Jallon P, Loiseau P, Loiseau J. Newly diagnosed unprovoked epileptic seizures: Presentation at diagnosis in CAROLE study. Coordination Active du Reseau Observatoire Longitudinal de l' Epilepsie. Epilepsia 2001;42:464-475.
16. Camfield CS, Camfield PR, Gordon K, Wirrell E, Dooley JM. Incidence of epilepsy in childhood and adolescence: A population-based study in Nova Scotia from 1977 to 1985. Epilepsia 1996;37:19-23.
17. Proposal for revised classification of epilepsies and epileptic syndromes. Commission on Classification and Terminology of the International League Against Epilepsy. Epilepsia 1989;30:389-399.
18. Fisher RS, van Emde Boas W, Blume W, Elger C, Genton P, Lee P, Engel J Jr. Epileptic seizures and epilepsy: Definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE). Epilepsia 2005;46:470-472.
19. Mullen SA, Suls A, De Jonghe P, Berkovic SF, Scheffer IE. Absence epilepsies with widely variable onset are a key feature of familial GLUT1 deficiency. Neurology 2010;75:432-440.
20. Dreifuss FE. Classification of epilepsies in childhood. In: Pediatric Epilepsy: Diagnosis and Therapy. (Pellock JM, Bourgeois BF, eds.) New York: Demos Medical Publishing, 2001:74-75.
21. Reutens DC, Berkovic SF. Idiopathic generalized epilepsy of adolescence: Are the syndromes clinically distinct? Neurology 1995;45:1469-1476.
22. Wolf P, Inoue Y. Therapeutic response of absence seizures in patients of an epilepsy clinic for adolescents and adults. J Neurol 1984;231:225-229.
23. Striano S, Capovilla G, Sofia V, Romeo A, Rubboli G, Striano P, Trenite DK. Eyelid myoclonia with absences (Jeavons syndrome): A welldefined idiopathic generalized epilepsy syndrome or a spectrum of photosensitive conditions? Epilepsia 2009;50:15-19.
24. Williams D. A study of thalamic and cortical rhythms in petit mal. Brain 1953;76:50-69.
25. Jasper HH, Droogleever-Fortuyn, J. Experimental studies on the functional anatomy of petit epilepsy. Res Publ Assoc Res Nerv Ment Dis 1947;26:272-298.
26. Snead OC. Basic mechanisms of generalized absence seizures. Ann Neurol 1995;37:146-157.
27. Carney PW, Masterton RA, Harvey AS, Scheffer IE, Berkovic SF, Jackson GD. The core network in absence epilepsy. Differences in cortical and thalamic BOLD response. Neurology 2010;75:904-911.
28. Moeller F, LeVan P, Muhle H, Stephani U, Dubeau F, Siniatchkin M, Gotman J. Absence seizures: Individual patterns revealed by EEG-fMRI. Epilepsia 2010;51:2000-2010.
29. Berman R, Negishi M, Vestal M, Spann M, Chung MH, Bai X, Purcaro M, Motelow JE, Danielson N, Dix-Cooper L, Enev M, Novotny EJ, Constable RT, Blumenfeld H. Simultaneous EEG, fMRI, and behavior in typical childhood absence seizures. Epilepsia 2010;51:2011-2022.
30. Hillebrand A, Barnes GR. A quantitative assessment of the sensitivity of whole-head MEG to activity in the adult human cortex. Neuroimage 2002;16:638-650.
31. Westmijse I, Ossenblok P, Gunning B, van Luijtelaar G. Onset and propagation of spike and slow wave discharges in human absence epilepsy: A MEG study. Epilepsia 2009;50:2538-2548.
32. Lennox WG. The heredity of epilepsy as told by relatives and twins. J Am Med Assoc 1951;146:529-536.
33. Yalcin O. Genes and molecular mechanisms involved in the epileptogenesis of idiopathic absence epilepsies. Seizure 2012;21:79-86.
34. Glauser T, Ben-Menachem E, Bourgeois B, Cnaan A, Chadwick D, Guerreiro C, Kalviainen R, Mattson R, Perucca E, Tomson T. ILAE treatment guidelines: Evidence-based analysis of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes. Epilepsia 2006;47:1094-1120.
35. Russo E, Citraro R, Scicchitano F, De Fazio S, Di Paola ED, Constanti A, De Sarro G. Comparison of the antiepileptogenic effects of an early long-term treatment with ethosuximide or levetiracetam in a genetic animal model of absence epilepsy. Epilepsia 2010;51:1560-1569.
36. Blumenfeld H, Klein JP, Schridde U, Vestal M, Rice T, Khera DS, Bashyal C, Giblin K, Paul-Laughinghouse C, Wang F, Phadke A, Mission J, Agarwal RK, Englot DJ, Motelow J, Nersesyan H, Waxman SG, Levin AR. Early treatment suppresses the development of spike-wave epilepsy in a rat model. Epilepsia 2008;49:400-409.
37. Wheless JW, Clarke DF, Carpenter D. Treatment of pediatric epilepsy: Expert opinion, 2005. J Child Neurol 2005;20:S1-56,S59-60.
38. Wheless JW, Clarke DF, Arzimanoglou A, Carpenter D. Treatment of pediatric epilepsy: European expert opinion, 2007. Epileptic Disord 2007;9:353-412.
39. Fattore C, Boniver C, Capovilla G, Cerminara C, Citterio A, Coppola G, Costa P, Darra F, Vecchi M, Perucca E. A multicenter, randomized, placebo-controlled trial of levetiracetam in children and adolescents with newly diagnosed absence epilepsy. Epilepsia 2011;52:802-809.
40. Groomes LB, Pyzik PL, Turner Z, Dorward JL, Goode VH, Kossoff EH. Do patients with absence epilepsy respond to ketogenic diets? J Child Neurol 2011;26:160-165.
41. Appleton RE, Panayiotopoulos CP, Acomb BA, Beirne M. Eyelid myoclonia with typical absences: An epilepsy syndrome. J Neurol Neurosurg Psychiatry 1993;56:1312-1316.
42. Berg AT, Shinnar S, Levy SR, Testa FM, Smith-Rapaport S, Beckerman B, Ebrahimi N. Two-year remission and subsequent relapse in children with newly diagnosed epilepsy. Epilepsia 2001;42:1553-1562.
43. Bouma PA, Westendorp RG, van Dijk JG, Peters AC, Brouwer OF. The outcome of absence epilepsy: A meta-analysis. Neurology 1996;47:802-808.
44. Fois A, Malandrini F, Mostardini R. Clinical experiences of petit mal. Brain Dev 1987;9:54-59.
45. Loiseau P, Pestre M, Dartigues JF, Commenges D, Barberger-Gateau C, Cohadon S. Long-term prognosis in two forms of childhood epilepsy: Typical absence seizures and epilepsy with rolandic (centrotemporal) EEG foci. Annals of neurology 1983;13:642-648.
46. Sato S, Dreifuss FE, Penry JK, Kirby DD, Palesch Y. Long-term follow-up of absence seizures. Neurology 1983;33:1590-1595.
47. Bartolomei F, Roger J, Bureau M, Genton P, Dravet C, Viallat D, Gastaut JL. Prognostic factors for childhood and juvenile absence epilepsies. Eur Neurol 1997;37:169-175.
48. Chaix Y, Daquin G, Monteiro F, Villeneuve N, Laguitton V, Genton P. Absence epilepsy with onset before age three years: A heterogeneous and often severe condition. Epilepsia 2003;44:944-949.
49. Grosso S, Galimberti D, Vezzosi P, Farnetani M, Di Bartolo RM, Bazzotti S, Morgese G, Balestri P. Childhood absence epilepsy: Evolution and prognostic factors. Epilepsia 2005;46:1796-1801.
50. Sillanpaa M, Jalava M, Kaleva O, Shinnar S. Long-term prognosis of seizures with onset in childhood. New Engl J Med 1998;338:1715-1722.
51. Sillanpaa M, Jalava M, Shinnar S. Epilepsy syndromes in patients with childhood-onset seizures in Finland. Pediatr Neurol 1999;21:533-537.
52. Sinclair DB, Unwala H. Absence epilepsy in childhood: Electroencephalography (EEG) does not predict outcome. J Child Neurol 2007;22:799-802.
53. Trinka E, Baumgartner S, Unterberger I, Unterrainer J, Luef G, Haberlandt E, Bauer G. Long-term prognosis for childhood and juvenile absence epilepsy. J Neurol 2004;251:1235-1241.
54. Wirrell E, Camfield C, Camfield P, Dooley J. Prognostic significance of failure of the initial antiepileptic drug in children with absence epilepsy. Epilepsia 2001;42:760-763.
55. Wirrell EC, Camfield CS, Camfield PR, Gordon KE, Dooley JM. Longterm prognosis of typical childhood absence epilepsy: Remission or progression to juvenile myoclonic epilepsy [see comments]. Neurology 1996;47:912-918.
56. Wirrell EC, Camfield PR, Camfield CS, Dooley JM, Gordon KE. Accidental injury is a serious risk in children with typical absence epilepsy [see comments]. Arch Neurol 1996;53:929-932.
57. Yoshinaga H, Ohtsuka Y, Tamai K, Tamura I, Ito M, Ohmori I, Oka E. EEG in childhood absence epilepsy. Seizure 2004;13:296-302.
58. Shinnar S, Berg AT, Moshe SL, Kang H, O'Dell C, Alemany M, Goldensohn ES, Hauser WA. Discontinuing antiepileptic drugs in children with epilepsy: A prospective study. Ann Neurol 1994;35:534-545.
59. Currier RD, Kooi KA, Saidman LJ. Prognosis of "Pure" Petit Mal; a Follow-up Study. Neurology 1963;13:959-967.
60. Livingston S, Torres I, Pauli LL, Rider RV. Petit mal epilepsy. Results of a prolonged follow-up study of 117 patients. JAMA 1965;194:227-232.
61. Charlton MH, Yahr MD. Long-term follow-up of patients with petit mal. Arch Neurol 1967;16:595-598.
62. Oller-Daurella L, Sanchez M. Evolucion de las ausencias tipicas. Rev Neurol (Barcelona) 1981;9:81-102.
63. Dieterich E, Baier WK, Doose H, Tuxhorn I, Fichsel H. Longterm followup of childhood epilepsy with absences. I. Epilepsy with absences at onset. Neuropediatrics 1985;16:149-154.
64. Loiseau P. Childhood absence epilepsy. In: Epileptic Syndromes in Infancy, Childhood and Adolescence. (Roger J, Bureau M, Dreifuss FE, Wolf P, eds.) London: John Libbey Eurotext, 1985:106-120.
65. Deonna T. Childhood absence epilepsy and accidents. Arch Neurol 1997;54:1063.
66. Tovia E, Goldberg-Stern H, Shahar E, Kramer U. Outcome of children with juvenile absence epilepsy. J Child Neurol 2006;21:766-768.
67. Giannakodimos S, Panayiotopoulos CP. Eyelid myoclonia with absences in adults: A clinical and video-EEG study. Epilepsia 1996;37:36-44.
68. Wirrell EC, Camfield CS, Camfield PR, Dooley JM, Gordon KE, Smith B. Long-term psychosocial outcome in typical absence epilepsy. Sometimes a wolf in sheeps' clothing. Arch Pediatr Adolesc Med 1997;151:152-158.
69. Caplan R, Siddarth P, Stahl L, Lanphier E, Vona P, Gurbani S, Koh S, Sankar R, Shields WD. Childhood absence epilepsy: Behavioral, cognitive, and linguistic comorbidities. Epilepsia 2008;49:1838-1846.
70. Vega C, Guo J, Killory B, Danielson N, Vestal M, Berman R, Martin L, Gonzalez JL, Blumenfeld H, Spann MN. Symptoms of anxiety and depression in childhood absence epilepsy. Epilepsia 2011;52:e70-74.
71. Levav M, Mirsky AF, Herault J, Xiong L, Amir N, Andermann E. Familial association of neuropsychological traits in patients with generalized and partial seizure disorders. J Clin Exp Neuropsychol 2002;24:311-326.
72. Pavone P, Bianchini R, Trifiletti RR, Incorpora G, Pavone A, Parano E. Neuropsychological assessment in children with absence epilepsy. Neurology 2001;56:1047-1051.
73. Henkin Y, Sadeh M, Kivity S, Shabtai E, Kishon-Rabin L, Gadoth N. Cognitive function in idiopathic generalized epilepsy of childhood. Dev Med Child Neurol 2005;47:126-132.
74. Vanasse CM, Beland R, Carmant L, Lassonde M. Impact of childhood epilepsy on reading and phonological processing abilities. Epilepsy Behav 2005;7:288-296.