Heteroannelated and 7-deoxygenated goniofufurone mimics with antitumour activity: Design, synthesis and preliminary SAR studies

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 20, 2013, Pages 5507-5510

  Popsavin, Velimir ^a   Francuz, Jovana ^a   Srećo Zelenović, Bojana ^a   Benedeković, Goran ^a   Popsavin, Mirjana ^a   Kojić, Vesna ^b   Bogdanović, Gordana ^b  

^a UNIVERSITY OF NOVI SAD   (Serbia)

^b ONCOLOGY INSTITUTE OF VOJVODINA   (Serbia)

Author keywords

Analogue synthesis; Antitumour styryl lactones; Goniofufurone mimics; SAR; Titanium(IV) fluoride

Indexed keywords

7 DEOXYGENATED GONIOFUFURONE; 7 EPI GONIOFUFURONE DERIVATIVE; 7 O BENZOYL 5 O BENZYL GONIOFUFURONE DERIVATIVE; ANTINEOPLASTIC AGENT; BENZOXEPANE; GONIOFUFURONE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DEOXYGENATION; DRUG DESIGN; DRUG SYNTHESIS; ENANTIOMER; FETUS; FETUS CELL; HUMAN; HUMAN CELL; IC 50; LUNG FIBROBLAST; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

ANALOGUE SYNTHESIS; ANTITUMOUR STYRYL LACTONES; GONIOFUFURONE MIMICS; SAR; TITANIUM(IV) FLUORIDE;

ANTINEOPLASTIC AGENTS; CELL LINE; CELL PROLIFERATION; CYCLIZATION; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; FLUORIDES; HUMANS; LACTONES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TITANIUM;

EID: 84884292569     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.08.069     Document Type: Article

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