Cisplatin-induced downregulation of SOX1 increases drug resistance by activating autophagy in non-small cell lung cancer cell

Biochemical and Biophysical Research Communications

Volumn 439, Issue 2, 2013, Pages 187-190

  Li, Ning ^a   Li, Xiaobing ^b   Li, Suyun ^a   Zhou, Suzhen ^a   Zhou, Qingwei ^a  

^a THE FIRST AFFILIATED HOSPITAL OF HENAN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b HENAN UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Cisplatin; Hypermethylation; Non small cell lung cancer; SOX1

Indexed keywords

CISPLATIN; DINUCLEOTIDE; MESSENGER RNA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SOX1; UVOMORULIN; VIMENTIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOPHAGY; CARCINOGENICITY; CELL ACTIVATION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DOWN REGULATION; DRUG RESISTANCE; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION; GENE SILENCING; GROWTH RATE; HUMAN; HUMAN CELL; HYPOTHESIS; LONG TERM EXPOSURE; LUNG NON SMALL CELL CANCER; MALE; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION SITE; UPREGULATION; WESTERN BLOTTING; WOUND HEALING;

CISPLATIN; HYPERMETHYLATION; NON-SMALL CELL LUNG CANCER; SOX1;

ANIMALS; ANTINEOPLASTIC AGENTS; AUTOPHAGY; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CISPLATIN; DNA METHYLATION; DOWN-REGULATION; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG; LUNG NEOPLASMS; MALE; MICE; MICE, NUDE; PROMOTER REGIONS, GENETIC; SOXB1 TRANSCRIPTION FACTORS;

EID: 84884290545     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.08.065     Document Type: Article

References (20)

1. Yu W., Jin C., Lou X., Han X., Li L., He Y., Zhang H., Ma K., Zhu J., Cheng L., Lin B. Global analysis of DNA methylation by methyl-capture sequencing reveals epigenetic control of cisplatin resistance in ovarian cancer cell. PLoS One 2011, 6:e29450.
2. Paul I., Chacko A.D., Stasik I., Busacca S., Crawford N., McCoy F., McTavish N., Wilson B., Barr M., O'Byrne K.J., Longley D.B., Fennell D.A. Acquired differential regulation of caspase-8 in cisplatin-resistant non-small-cell lung cancer. Cell Death Dis. 2012, 3:e449.
3. Chang X., Monitto C.L., Demokan S., Kim M.S., Chang S.S., Zhong X., Califano J.A., Sidransky D. Identification of hypermethylated genes associated with cisplatin resistance in human cancers. Cancer Res. 2010, 70:2870-2879.
4. Kormish J.D., Sinner D., Zorn A.M. Interactions between SOX factors and Wnt/beta-catenin signaling in development and disease. Dev. Dyn. 2010, 239:56-68.
5. Shih Y.L., Hsieh C.B., Yan M.D., Tsao C.M., Hsieh T.Y., Liu C.H., Lin Y.W. Frequent concomitant epigenetic silencing of SOX1 and secreted frizzled-related proteins (SFRPs) in human hepatocellular carcinoma. J. Gastroenterol. Hepatol. 2013, 28:551-559.
6. Tsao C.M., Yan M.D., Shih Y.L., Yu P.N., Kuo C.C., Lin W.C., Li H.J., Lin Y.W. SOX1 functions as a tumor suppressor by antagonizing the WNT/beta-catenin signaling pathway in hepatocellular carcinoma. Hepatology 2012, 56:2277-2287.
7. Cho Y.Y., Kim D.J., Lee H.S., Jeong C.H., Cho E.J., Kim M.O., Byun S., Lee K.Y., Yao K., Carper A., Langfald A., Bode A.M., Dong Z. Autophagy and cellular senescence mediated by Sox2 suppress malignancy of cancer cells. PLoS One 2013, 8:e57172.
8. Ren J.H., He W.S., Nong L., Zhu Q.Y., Hu K., Zhang R.G., Huang L.L., Zhu F., Wu G. Acquired cisplatin resistance in human lung adenocarcinoma cells is associated with enhanced autophagy. Cancer Biother. Radiopharm. 2010, 25:75-80.
9. Xu N., Zhang J., Shen C., Luo Y., Xia L., Xue F., Xia Q. Cisplatin-induced downregulation of miR-199a-5p increases drug resistance by activating autophagy in HCC cell. Biochem. Biophys. Res. Commun. 2012, 423:826-831.
10. Xu Y., An Y., Wang Y., Zhang C., Zhang H., Huang C., Jiang H., Wang X., Li X. MiR-101 inhibits autophagy and enhances cisplatin-induced apoptosis in hepatocellular carcinoma cells. Oncol. Rep. 2013, 29:2019-2024.
11. Lai H.C., Lin Y.W., Huang T.H., Yan P., Huang R.L., Wang H.C., Liu J., Chan M.W., Chu T.Y., Sun C.A., Chang C.C., Yu M.H. Identification of novel DNA methylation markers in cervical cancer. Int. J. Cancer 2008, 123:161-167.
12. Ji X.D., Li G., Feng Y.X., Zhao J.S., Li J.J., Sun Z.J., Shi S., Deng Y.Z., Xu J.F., Zhu Y.Q., Koeffler H.P., Tong X.J., Xie D. EphB3 is overexpressed in non-small-cell lung cancer and promotes tumor metastasis by enhancing cell survival and migration. Cancer Res. 2011, 71:1156-1166.
13. Koga T., Takeshita M., Yano T., Maehara Y., Sueishi K. CHFR hypermethylation and EGFR mutation are mutually exclusive and exhibit contrastive clinical backgrounds and outcomes in non-small cell lung cancer. Int. J. Cancer 2011, 128:1009-1017.
14. Kuroda H., Mochizuki S., Shimoda M., Chijiiwa M., Kamiya K., Izumi Y., Watanabe M., Horinouchi H., Kawamura M., Kobayashi K., Okada Y. ADAM28 is a serological and histochemical marker for non-small-cell lung cancers. Int. J. Cancer 2010, 127:1844-1856.
15. Ma Q., Li P., Xu M., Yin J., Su Z., Li W., Zhang J. Ku80 is highly expressed in lung adenocarcinoma and promotes cisplatin resistance. J. Exp. Clin. Cancer Res. 2012, 31:99.
16. Liu F., Liu Q., Yang D., Bollag W.B., Robertson K., Wu P., Liu K. Verticillin A overcomes apoptosis resistance in human colon carcinoma through DNA methylation-dependent upregulation of BNIP3. Cancer Res. 2011, 71:6807-6816.
17. Han W., Pan H., Chen Y., Sun J., Wang Y., Li J., Ge W., Feng L., Lin X., Wang X., Wang X., Jin H. EGFR tyrosine kinase inhibitors activate autophagy as a cytoprotective response in human lung cancer cells. PLoS One 2011, 6:e18691.
18. Olszewski U., Deally A., Tacke M., Hamilton G. Alterations of phosphoproteins in NCI-H526 small cell lung cancer cells involved in cytotoxicity of cisplatin and titanocene Y. Neoplasia 2012, 14:813-822.
19. Lee S.W., Song Y.S., Lee S.Y., Yoon Y.G., Lee S.H., Park B.S., Yun I., Choi H., Kim K., Chung W.T., Yoo Y.H. Downregulation of protein kinase CK2 activity facilitates tumor necrosis factor-alpha-mediated chondrocyte death through apoptosis and autophagy. PLoS One 2011, 6:e19163.
20. Chao T.K., Yo Y.T., Liao Y.P., Wang Y.C., Su P.H., Huang T.S., Lai H.C. LIM-homeobox transcription factor 1, alpha (LMX1A) inhibits tumourigenesis, epithelial-mesenchymal transition and stem-like properties of epithelial ovarian cancer. Gynecol. Oncol. 2013, 128:475-482.