Identification of genes involved in neisseria meningitidis colonization

Infection and Immunity

Volumn 81, Issue 9, 2013, Pages 3375-3381

  Jamet, Anne ^a,b,c   Euphrasie, Daniel ^a,b   Martin, Patricia ^a,d,e,f   Nassif, Xavier ^a,b,c  

^a INSERM   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c HÔPITAL NECKER ENFANTS MALADES   (France)

^d CEMAGREF   (France)

^e CNRS   (France)

^f UNIVERSITÉ PAUL SABATIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

THIOREDOXIN;

ADAPTATION; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIAL STRAIN; BIOMASS; CONFOCAL MICROSCOPE; CONTROLLED STUDY; EPITHELIUM CELL; GENE IDENTIFICATION; HUMAN; HUMAN CELL; HYPOXIA; IN VITRO STUDY; MUTAGENESIS; NEISSERIA MENINGITIDIS; NONHUMAN; PRIORITY JOURNAL; STRESS; TRANSPOSON;

EID: 84884257971     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00421-13     Document Type: Article

References (41)

1. Stephens DS, Greenwood B, Brandtzaeg P. 2007. Epidemic meningitis, meningococcaemia, and Neisseria meningitidis. Lancet 369:2196-2210.
2. Seib KL, Serruto D, Oriente F, Delany I, Adu-Bobie J, Veggi D, Arico B, Rappuoli R, Pizza M. 2009. Factor H-binding protein is important for meningococcal survival in human whole blood and serum and in the presence of the antimicrobial peptide LL-37. Infect. Immun. 77:292-299.
3. Read RC, Fox A, Miller K, Gray T, Jones N, Borrows R, Jones DM, Finch RG. 1995. Experimental infection of human nasal mucosal explants with Neisseria meningitidis. J. Med. Microbiol. 42:353-361.
4. Rayner CF, Dewar A, Moxon ER, Virji M, Wilson R. 1995. The effect of variations in the expression of pili on the interaction of Neisseria meningitidis with human nasopharyngeal epithelium. J. Infect. Dis. 171:113-121.
5. Nassif X, So M. 1995. Interaction of pathogenic neisseriae with nonphagocytic cells. Clin. Microbiol. Rev. 8:376-388.
6. Pujol C, Eugene E, de Saint Martin L, Nassif X. 1997. Interaction of Neisseria meningitidis with a polarized monolayer of epithelial cells. Infect. Immun. 65:4836-4842.
7. Pujol C, Eugene E, Marceau M, Nassif X. 1999. The meningococcal PilT protein is required for induction of intimate attachment to epithelial cells following pilus-mediated adhesion. Proc. Natl. Acad. Sci. U. S. A. 96:4017-4022.
8. Neil RB, Shao JQ, Apicella MA. 2009. Biofilm formation on human airway epithelia by encapsulated Neisseria meningitidis serogroup B. Microbes Infect. 11:281-287.
9. Lappann M, Vogel U. 2010. Biofilm formation by the human pathogen Neisseria meningitidis. Med. Microbiol. Immunol. 199:173-183.
10. Geoffroy MC, Floquet S, Metais A, Nassif X, Pelicic V. 2003. Large-scale analysis of the meningococcus genome by gene disruption: resistance to complement-mediated lysis. Genome Res. 13:391-398.
11. Lappann M, Haagensen JA, Claus H, Vogel U, Molin S. 2006. Meningococcal biofilm formation: structure, development, and phenotypes in a standardized continuous flow system. Mol. Microbiol. 62:1292-1309.
12. Yi K, Rasmussen AW, Gudlavalleti SK, Stephens DS, Stojiljkovic I. 2004. Biofilm formation by Neisseria meningitidis. Infect. Immun. 72:6132-6138.
13. van Alen T, Claus H, Zahedi RP, Groh J, Blazyca H, Lappann M, Sickmann A, Vogel U. 2010. Comparative proteomic analysis of biofilm and planktonic cells of Neisseria meningitidis. Proteomics 10:4512-4521.
14. Phillips NJ, Steichen CT, Schilling B, Post DM, Niles RK, Bair TB, Falsetta ML, Apicella MA, Gibson BW. 2012. Proteomic analysis of Neisseria gonorrhoeae biofilms shows shift to anaerobic respiration and changes in nutrient transport and outer membrane proteins. PLoS One 7:e38303. doi:10.1371/journal.pone.0038303.
15. Falsetta ML, Bair TB, Ku SC, Vanden Hoven RN, Steichen CT, McEwan AG, Jennings MP, Apicella MA. 2009. Transcriptional profiling identifies the metabolic phenotype of gonococcal biofilms. Infect. Immun. 77:3522-3532.
16. Rusniok C, Vallenet D, Floquet S, Ewles H, Mouze-Soulama C, Brown D, Lajus A, Buchrieser C, Medigue C, Glaser P, Pelicic V. 2009. NeMeSys: a biological resource for narrowing the gap between sequence and function in the human pathogen Neisseria meningitidis. Genome Biol. 10:R110.
17. Mairey E, Genovesio A, Donnadieu E, Bernard C, Jaubert F, Pinard E, Seylaz J, Olivo-Marin JC, Nassif X, Dumenil G. 2006. Cerebral microcirculation shear stress levels determine Neisseria meningitidis attachment sites along the blood-brain barrier. J. Exp. Med. 203:1939-1950.
18. Heydorn A, Nielsen AT, Hentzer M, Sternberg C, Givskov M, Ersboll BK, Molin S. 2000. Quantification of biofilm structures by the novel computer program COMSTAT. Microbiology 146(Pt 10):2395-2407.
19. Henriques A, Carvalho F, Pombinho R, Reis O, Sousa S, Cabanes D. 2012. PCR-based screening of targeted mutants for the fast and simultaneous identification of bacterial virulence factors. Biotechniques 2012:2012. doi:10.2144/000113906.
20. Lehoux DE, Sanschagrin F, Levesque RC. 1999. Defined oligonucleotide tag pools and PCR screening in signature-tagged mutagenesis of essential genes from bacteria. Biotechniques 26:473-480.
21. Mehr IJ, Long CD, Serkin CD, Seifert HS. 2000. A homologue of the recombination-dependent growth gene, rdgC, is involved in gonococcal pilin antigenic variation. Genetics 154:523-532.
22. Honisch U, Zumft WG. 2003. Operon structure and regulation of the nos gene region of Pseudomonas stutzeri, encoding an ABC-type ATPase for maturation of nitrous oxide reductase. J. Bacteriol. 185:1895-1902.
23. Tzeng YL, Ambrose KD, Zughaier S, Zhou X, Miller YK, Shafer WM, Stephens DS. 2005. Cationic antimicrobial peptide resistance in Neisseria meningitidis. J. Bacteriol. 187:5387-5396.
24. Seib KL, Wu HJ, Srikhanta YN, Edwards JL, Falsetta ML, Hamilton AJ, Maguire TL, Grimmond SM, Apicella MA, McEwan AG, Jennings MP. 2007. Characterization of the OxyR regulon of Neisseria gonorrhoeae. Mol. Microbiol. 63:54-68.
25. Falsetta ML, Steichen CT, McEwan AG, Cho C, Ketterer M, Shao J, Hunt J, Jennings MP, Apicella MA. 2011. The composition and metabolic phenotype of Neisseria gonorrhoeae biofilms. Front. Microbiol. 2:75.
26. Potter AJ, Kidd SP, Edwards JL, Falsetta ML, Apicella MA, Jennings MP, McEwan AG. 2009. Esterase D is essential for protection of Neisseria gonorrhoeae against nitrosative stress and for bacterial growth during interaction with cervical epithelial cells. J. Infect. Dis. 200:273-278.
27. Falsetta ML, McEwan AG, Jennings MP, Apicella MA. 2010. Anaerobic metabolism occurs in the substratum of gonococcal biofilms and may be sustained in part by nitric oxide. Infect. Immun. 78:2320-2328.
28. Townsend R, Goodwin L, Stevanin TM, Silcocks PB, Parker A, Maiden MC, Read RC. 2002. Invasion by Neisseria meningitidis varies widely between clones and among nasopharyngeal mucosae derived from adult human hosts. Microbiology 148:1467-1474.
29. Exley RM, Sim R, Goodwin L, Winterbotham M, Schneider MC, Read RC, Tang CM. 2009. Identification of meningococcal genes necessary for colonization of human upper airway tissue. Infect. Immun. 77:45-51.
30. O'Dwyer CA, Li MS, Langford PR, Kroll JS. 2009. Meningococcal biofilm growth on an abiotic surface: a model for epithelial colonization? Microbiology 155:1940-1952.
31. Lissenden S, Mohan S, Overton T, Regan T, Crooke H, Cardinale JA, Householder TC, Adams P, O'Conner CD, Clark VL, Smith H, Cole JA. 2000. Identification of transcription activators that regulate gonococcal adaptation from aerobic to anaerobic or oxygen-limited growth. Mol. Microbiol. 37:839-855.
32. Bartnikas TB, Wang Y, Bobo T, Veselov A, Scholes CP, Shapleigh JP. 2002. Characterization of a member of the NnrR regulon in Rhodobacter sphaeroides 2.4.3 encoding a haem-copper protein. Microbiology 148:825-833.
33. Stern AM, Hay AJ, Liu Z, Desland FA, Zhang J, Zhong Z, Zhu J. 2012. The NorR regulon is critical for Vibrio cholerae resistance to nitric oxide and sustained colonization of the intestines. mBio 3:e00013-12. doi:10.1128/mBio.00013-12.
34. Potter AJ, Kidd SP, Edwards JL, Falsetta ML, Apicella MA, Jennings MP, McEwan AG. 2009. Thioredoxin reductase is essential for protection of Neisseria gonorrhoeae against killing by nitric oxide and for bacterial growth during interaction with cervical epithelial cells. J. Infect. Dis. 199:227-235.
35. Lim KH, Jones CE, Vanden Hoven RN, Edwards JL, Falsetta ML, Apicella MA, Jennings MP, McEwan AG. 2008. Metal binding specificity of the MntABC permease of Neisseria gonorrhoeae and its influence on bacterial growth and interaction with cervical epithelial cells. Infect. Immun. 76:3569-3576.
36. Chen NH, Counago RM, Djoko KY, Jennings MP, Apicella MA, Kobe B, McEwan AG. 2013. A glutathione-dependent detoxification system is required for formaldehyde resistance and optimal survival of Neisseria meningitidis in biofilms. Antioxid. Redox Signal. 18:743-755.
37. Weimar JD, DiRusso CC, Delio R, Black PN. 2002. Functional role of fatty acyl-coenzyme A synthetase in the transmembrane movement and activation of exogenous long-chain fatty acids: amino acid residues within the ATP/AMP signature motif of Escherichia coli FadD are required for enzyme activity and fatty acid transport. J. Biol. Chem. 277:29369-29376.
38. Ray S, Chatterjee E, Chatterjee A, Paul K, Chowdhury R. 2011. A fadD mutant of Vibrio cholerae is impaired in the production of virulence factors and membrane localization of the virulence regulatory protein TcpP. Infect. Immun. 79:258-266.
39. Soto MJ, Fernandez-Pascual M, Sanjuan J, Olivares J. 2002. A fadD mutant of Sinorhizobium meliloti shows multicellular swarming migration and is impaired in nodulation efficiency on alfalfa roots. Mol. Microbiol. 43:371-382.
40. Lucas RL, Lostroh CP, DiRusso CC, Spector MP, Wanner BL, Lee CA. 2000. Multiple factors independently regulate hilA and invasion gene expression in Salmonella enterica serovar Typhimurium. J. Bacteriol. 182:1872-1882.
41. Kang Y, Zarzycki-Siek J, Walton CB, Norris MH, Hoang TT. 2010. Multiple FadD acyl-CoA synthetases contribute to differential fatty acid degradation and virulence in Pseudomonas aeruginosa. PLoS One 5:e13557. doi:10.1371/journal.pone.0013557.