Cyclic guanosine monophosphate and the dependent protein kinase regulate lymphatic contractility in rat thoracic duct

Journal of Physiology

Volumn 591, Issue 18, 2013, Pages 4549-4565

  Gasheva, Olga Yu ^a   Gashev, Anatoliy A ^a   Zawieja, David C ^a  

^a TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 (4 CHLOROPHENYLTHIO) CYCLIC AMP; 8 (4 CHLOROPHENYLTHIO) CYCLIC GMP; ADENOSINE 3',5' PHOSPHOROTHIOATE; CYCLIC GMP; N ACETYL S NITROSOPENICILLAMINE; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE; PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTICLE; CAVA VEIN; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; LYMPHATIC CONTRACTILITY; MALE; MUSCLE CELL; MUSCLE CONTRACTILITY; NONHUMAN; PRESSURE GRADIENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; THORACIC DUCT; WESTERN BLOTTING;

ANIMALS; CYCLIC GMP; CYCLIC GMP-DEPENDENT PROTEIN KINASES; GUANYLATE CYCLASE; ISOENZYMES; LYMPHATIC VESSELS; MALE; MUSCLE CONTRACTION; NITRIC OXIDE; OXADIAZOLES; PROTEIN KINASE INHIBITORS; QUINOXALINES; RATS; RATS, SPRAGUE-DAWLEY; THORACIC DUCT;

EID: 84884236509     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2013.258681     Document Type: Article

References (49)

1. Ammendola A, Geiselhoringer A, Hofmann F & Schlossmann J (2001). Molecular determinants of the interaction between the inositol 1, 4, 5-trisphosphate receptor-associated cGMP kinase substrate (IRAG) and cGMP kinase Ibeta. J Biol Chem 276, 24153-24159.
2. Beavo JA & Brunton LL (2002). Cyclic nucleotide research - still expanding after half a century. Nature Rev Mol Cell Biol 3, 710-718.
3. Benoit JN, Zawieja DC, Goodman AH & Granger HJ (1989). Characterization of intact mesenteric lymphatic pump and its responsiveness to acute edemagenic stress. Am J Physiol Heart Circ Physiol 257, H2059-2069.
4. Bohlen HG, Gasheva OY & Zawieja DC (2011). Nitric oxide formation by lymphatic bulb and valves is a major regulatory component of lymphatic pumping. Am J Physiol Heart Circ Physiol 301, H1897-1906.
5. Bohlen HG, Wang W, Gashev A, Gasheva O & Zawieja D (2009). Phasic contractions of rat mesenteric lymphatics increase basal and phasic nitric oxide generation in vivo. Am J Physiol Heart Circ Physiol 297, H1319-1328.
6. Davis MJ (2005). An improved, computer-based method to automatically track internal and external diameter of isolated microvessels. Microcirculation 12, 361-372.
7. Davis MJ, Zawieja DC & Gashev AA (2006). Automated measurement of diameter and contraction waves of cannulated lymphatic microvessels. Lymphat Res Biol 4, 3-10.
8. Dixon JB, Greiner ST, Gashev AA, Cote GL, Moore JE & Zawieja DC (2006). Lymph flow, shear stress, and lymphocyte velocity in rat mesenteric prenodal lymphatics. Microcirculation 13, 597-610.
9. + ATPase in relaxations of bovine isolated bronchioles induced by GEA 3175, an NO donor. Pulm Pharmacol Ther 19, 179-188.
10. Friebe A & Koesling D (2003). Regulation of nitric oxide-sensitive guanylyl cyclase. Circ Res 93, 96-105.
11. Gashev AA (2002). Physiologic aspects of lymphatic contractile function: current perspectives. Ann N Y Acad Sci 979, 178-187; discussion 188-196.
12. Gashev AA (2008). Lymphatic vessels: pressure- and flow-dependent regulatory reactions. Ann N Y Acad Sci 1131, 100-109.
13. Gashev AA (2010). Basic mechanisms controlling lymph transport in the mesenteric lymphatic net. Ann N Y Acad Sci 1207 Suppl 1, E16-20.
14. Gashev AA & Zawieja DC (2010). Hydrodynamic regulation of lymphatic transport and the impact of aging. Pathophysiology 17, 277-287.
15. Gashev AA, Davis MJ & Zawieja DC (2002). Inhibition of the active lymph pump by flow in rat mesenteric lymphatics and thoracic duct. J Physiol 540, 1023-1037.
16. Gashev AA, Davis MJ, Delp MD & Zawieja DC (2004). Regional variations of contractile activity in isolated rat lymphatics. Microcirculation 11, 477-492.
17. Gashev AA, Delp MD & Zawieja DC (2006). Inhibition of active lymph pump by simulated microgravity in rats. Am J Physiol Heart Circ Physiol 290, H2295-2308.
18. Gashev AA, Zhang RZ, Muthuchamy M, Zawieja DC & Davis MJ (2012). Regional heterogeneity of length-tension relationships in rat lymph vessels. Lymphat Res Biol 10, 14-19.
19. Gasheva OY, Zawieja DC & Gashev AA (2006). Contraction-initiated NO-dependent lymphatic relaxation: a self-regulatory mechanism in rat thoracic duct. J Physiol 575, 821-832.
20. Gasheva OY, Knippa K, Nepiushchikh ZV, Muthuchamy M & Gashev AA (2007). Age-related alterations of active pumping mechanisms in rat thoracic duct. Microcirculation 14, 827-839.
21. Geiselhoringer A, Werner M, Sigl K, Smital P, Worner R, Acheo L, Stieber J, Weinmeister P, Feil R, Feil S, Wegener J, Hofmann F & Schlossmann J (2004). IRAG is essential for relaxation of receptor-triggered smooth muscle contraction by cGMP kinase. EMBO J 23, 4222-4231.
22. Godfrey EW & Schwarte RC (2003). The role of nitric oxide signalling in the formation of the neuromuscular junction. J Neurocytol 32, 591-602.
23. Godfrey EW & Schwarte RC (2010). Nitric oxide and cyclic GMP regulate early events in agrin signalling in skeletal muscle cells. Exp Cell Res 316, 1935-1945.
24. Godfrey EW, Longacher M, Neiswender H, Schwarte RC & Browning DD (2007). Guanylate cyclase and cyclic GMP-dependent protein kinase regulate agrin signalling at the developing neuromuscular junction. Dev Biol 307, 195-201.
25. Granger HJ, Kovalcheck S, Zweifach BW & Barnes GE (1977). Quantitative analysis of active lymphatic pumping. In Proceedings of the VII Summer Computer Simulation Conference, pp. 562-565. Simulation Councils, Inc., La Jolla, CA.
26. Mizuno R, Koller A & Kaley G (1998). Regulation of the vasomotor activity of lymph microvessels by nitric oxide and prostaglandins. Am J Physiol Regul Integr Comp Physiol 274, R790-796.
27. Mochizuki S, Sipkema P, Goto M, Hiramatsu O, Nakamoto H, Toyota E, Kajita T, Shigeto F, Yada T, Ogasawara Y & Kajiya F (2005). Exogenous NO suppresses flow-induced endothelium-derived NO production because of depletion of tetrahydrobiopterin. Am J Physiol Heart Circ Physiol 288, H553-558.
28. Murad F (2006). Shattuck Lecture. Nitric oxide and cyclic GMP in cell signalling and drug development. N Engl J Med 355, 2003-2011.
29. Muthuchamy M, Gashev A, Boswell N, Dawson N & Zawieja D (2003). Molecular and functional analyses of the contractile apparatus in lymphatic muscle. FASEB J 17, 920-922.
30. Nepiyushchikh ZV, Chakraborty S, Wang W, Davis MJ, Zawieja DC & Muthuchamy M (2011). Differential effects of myosin light chain kinase inhibition on contractility, force development and myosin light chain 20 phosphorylation of rat cervical and thoracic duct lymphatics. J Physiol 589, 5415-5429.
31. Nimmegeers S, Sips P, Buys E, Decaluwe K, Brouckaert P & Van de Voorde J (2008). Role of the soluble guanylyl cyclase alpha1-subunit in mice corpus cavernosum smooth muscle relaxation. Int J Impot Res 20, 278-284.
32. Ohhashi T & Takahashi N (1991). Acetylcholine-induced release of endothelium-derived relaxing factor from lymphatic endothelial cells. Am J Physiol Heart Circ Physiol 260, H1172-1178.
33. Ohhashi T & Yokoyama S (1994). Nitric oxide and the lymphatic system. Jpn J Physiol 44, 327-342.
34. Ohhashi T, Mizuno R, Ikomi F & Kawai Y (2005). Current topics of physiology and pharmacology in the lymphatic system. Pharmacol Ther 105, 165-188.
35. PHS Policy (1996). http://grants.nih.gov/grants/olaw/references/phspol.htm
36. Qin X, Zheng X, Qi H, Dou D, Raj JU & Gao Y (2007). cGMP-dependent protein kinase in regulation of basal tone and in nitroglycerin- and nitric-oxide-induced relaxation in porcine coronary artery. Pflugers Arch 454, 913-923.
37. Rastaldo R, Pagliaro P, Cappello S, Penna C, Mancardi D, Westerhof N & Losano G (2007). Nitric oxide and cardiac function. Life Sci 81, 779-793.
38. Russo I, Doronzo G, Mattiello L, De Salve A, Trovati M & Anfossi G (2004). The activity of constitutive nitric oxide synthase is increased by the pathway cAMP/cAMP-activated protein kinase in human platelets. New insights into the antiaggregating effects of cAMP-elevating agents. Thromb Res 114, 265-273.
39. Ruth P, Landgraf W, Keilbach A, May B, Egleme C & Hofmann F (1991). The activation of expressed cGMP-dependent protein kinase isozymes I alpha and I beta is determined by the different amino-termini. Eur J Biochem 202, 1339-1344.
40. Rybalkin SD, Yan C, Bornfeldt KE & Beavo JA (2003). Cyclic GMP phosphodiesterases and regulation of smooth muscle function. Circ Res 93, 280-291.
41. Schlossmann J, Ammendola A, Ashman K, Zong X, Huber A, Neubauer G, Wang GX, Allescher HD, Korth M, Wilm M, Hofmann F & Ruth P (2000). Regulation of intracellular calcium by a signalling complex of IRAG, IP3 receptor and cGMP kinase Ibeta. Nature 404, 197-201.
42. Shukla P, Sun C & O'Rourke ST (2012). Melatonin inhibits nitric oxide signalling by increasing PDE5 phosphorylation in coronary arteries. Am J Physiol Heart Circ Physiol 303, H1418-1425.
43. Terluk M, Cunha Da Silva E, Antunes T & Assreuy J (2004). The presence of the endothelial layer reduces nitric oxide-induced hyporesponsiveness to phenylephrine in rat aorta. Endothelium 11, 181-187.
44. Tsunemoto H, Ikomi F & Ohhashi T (2003). Flow-mediated release of nitric oxide from lymphatic endothelial cells of pressurized canine thoracic duct. Jpn J Physiol 53, 157-163.
45. von der Weid PY, Zhao J & Van Helden DF (2001). Nitric oxide decreases pacemaker activity in lymphatic vessels of guinea pig mesentery. Am J Physiol Heart Circ Physiol 280, H2707-2716.
46. Williams JM, White CR, Chang MM, Injeti ER, Zhang L & Pearce WJ (2006). Chronic hypoxic decreases in soluble guanylate cyclase protein and enzyme activity are age dependent in fetal and adult ovine carotid arteries. J Appl Physiol 100, 1857-1866.
47. Ying L, Xu X, Liu J, Dou D, Yu X, Ye L, He Q & Gao Y (2012). Heterogeneity in relaxation of different sized porcine coronary arteries to nitrovasodilators: role of PKG and MYPT1. Pflugers Arch 463, 257-268.
48. Yokoyama S & Ohhashi T (1993). Effects of acetylcholine on spontaneous contractions in isolated bovine mesenteric lymphatics. Am J Physiol Heart Circ Physiol 264, H1460-1464.
49. Zawieja DC, Greiner ST, Davis KL, Hinds WM & Granger HJ (1991). Reactive oxygen metabolites inhibit spontaneous lymphatic contractions. Am J Physiol Heart Circ Physiol 260, H1935-1943.