-
1
-
-
84884252262
-
Stabilized cyclopropane analogs of the splicing inhibitor FD-895
-
DOI: 10.1021/jm400861t
-
Villa, R.; Kashyap, M. K.; Kumar, D.; Kipps, T. J.; Castro, J. E.; La Clair, J. J.; Burkart, M. D. Stabilized cyclopropane analogs of the splicing inhibitor FD-895. J. Med. Chem. 2013, DOI: 10.1021/jm400861t.
-
(2013)
J. Med. Chem.
-
-
Villa, R.1
Kashyap, M.K.2
Kumar, D.3
Kipps, T.J.4
Castro, J.E.5
La Clair, J.J.6
Burkart, M.D.7
-
2
-
-
84858308226
-
Natural products as sources of new drugs over the 30 years from 1981 to 2010
-
Newman, D. J.; Cragg, G. M. Natural products as sources of new drugs over the 30 years from 1981 to 2010 J. Nat. Prod. 2012, 75, 311-335
-
(2012)
J. Nat. Prod.
, vol.75
, pp. 311-335
-
-
Newman, D.J.1
Cragg, G.M.2
-
3
-
-
44249098800
-
Natural products to drugs: Natural product-derived compounds in clinical trials
-
Butler, M. S. Natural products to drugs: natural product-derived compounds in clinical trials Nat. Prod. Rep. 2008, 25, 475-516
-
(2008)
Nat. Prod. Rep.
, vol.25
, pp. 475-516
-
-
Butler, M.S.1
-
4
-
-
77955014467
-
Natural products as chemical probes
-
Carlson, E. E. Natural products as chemical probes ACS Chem. Biol. 2010, 5, 639-653
-
(2010)
ACS Chem. Biol.
, vol.5
, pp. 639-653
-
-
Carlson, E.E.1
-
6
-
-
0028556452
-
Isolation and characterization of a new 12-membered macrolide FD-895
-
Seki-Asano, M.; Okazaki, T.; Yamagishi, M.; Sakai, N.; Takayama, Y.; Hanada, K.; Morimoto, S.; Takatsuki, A.; Mizoue, K. Isolation and characterization of a new 12-membered macrolide FD-895 J. Antibiot. (Tokyo) 1994, 47, 1395-1401
-
(1994)
J. Antibiot. (Tokyo)
, vol.47
, pp. 1395-1401
-
-
Seki-Asano, M.1
Okazaki, T.2
Yamagishi, M.3
Sakai, N.4
Takayama, Y.5
Hanada, K.6
Morimoto, S.7
Takatsuki, A.8
Mizoue, K.9
-
7
-
-
1842832148
-
Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. I. Taxonomy, fermentation, isolation and screening
-
Sakai, T.; Sameshima, T.; Matsufuji, M.; Kawamura, N.; Dobashi, K.; Mizui, Y. Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. I. Taxonomy, fermentation, isolation and screening J. Antibiot. (Tokyo) 2004, 57, 173-179
-
(2004)
J. Antibiot. (Tokyo)
, vol.57
, pp. 173-179
-
-
Sakai, T.1
Sameshima, T.2
Matsufuji, M.3
Kawamura, N.4
Dobashi, K.5
Mizui, Y.6
-
8
-
-
1842865015
-
Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. II. Physico-chemical properties and structure elucidation
-
Sakai, T.; Asai, N.; Okuda, A.; Kawamura, N.; Mizui, Y. Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. II. Physico-chemical properties and structure elucidation J. Antibiot. (Tokyo) 2004, 57, 180-187
-
(2004)
J. Antibiot. (Tokyo)
, vol.57
, pp. 180-187
-
-
Sakai, T.1
Asai, N.2
Okuda, A.3
Kawamura, N.4
Mizui, Y.5
-
9
-
-
1842865013
-
Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. III. in vitro and in vivo antitumor activities
-
Mizui, Y.; Sakai, T.; Iwata, M.; Uenaka, T.; Okamoto, K.; Shimizu, H.; Yamori, T.; Yoshimatsu, K.; Asada, M. Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. III. In vitro and in vivo antitumor activities J. Antibiot. (Tokyo) 2004, 57, 188-196
-
(2004)
J. Antibiot. (Tokyo)
, vol.57
, pp. 188-196
-
-
Mizui, Y.1
Sakai, T.2
Iwata, M.3
Uenaka, T.4
Okamoto, K.5
Shimizu, H.6
Yamori, T.7
Yoshimatsu, K.8
Asada, M.9
-
10
-
-
34548104659
-
Splicing factor SF3b as a target of the antitumor natural product pladienolide
-
Kotake, Y.; Sagane, K.; Owa, T.; Mimori-Kiyosue, Y.; Shimizu, H.; Uesugi, M.; Ishihama, Y.; Iwata, M.; Mizui, Y. Splicing factor SF3b as a target of the antitumor natural product pladienolide Nat. Chem. Biol. 2007, 3, 570-575
-
(2007)
Nat. Chem. Biol.
, vol.3
, pp. 570-575
-
-
Kotake, Y.1
Sagane, K.2
Owa, T.3
Mimori-Kiyosue, Y.4
Shimizu, H.5
Uesugi, M.6
Ishihama, Y.7
Iwata, M.8
Mizui, Y.9
-
11
-
-
82755192848
-
Biological validation that SF3b is a target of the antitumor macrolide pladienolide
-
Yokoi, A.; Kotake, Y.; Takahashi, K.; Kadowaki, T.; Matsumoto, Y.; Minoshima, Y.; Sugi, N. H.; Sagane, K.; Hamaguchi, M.; Iwata, M.; Mizui, Y. Biological validation that SF3b is a target of the antitumor macrolide pladienolide FEBS J. 2011, 278, 4870-4880
-
(2011)
FEBS J.
, vol.278
, pp. 4870-4880
-
-
Yokoi, A.1
Kotake, Y.2
Takahashi, K.3
Kadowaki, T.4
Matsumoto, Y.5
Minoshima, Y.6
Sugi, N.H.7
Sagane, K.8
Hamaguchi, M.9
Iwata, M.10
Mizui, Y.11
-
12
-
-
84871924824
-
The development and application of small molecule modulators of SF3b as therapeutic agents for cancer
-
Webb, T. R.; Joyner, A. S.; Potter, P. M. The development and application of small molecule modulators of SF3b as therapeutic agents for cancer Drug Discovery Today 2013, 18, 43-49
-
(2013)
Drug Discovery Today
, vol.18
, pp. 43-49
-
-
Webb, T.R.1
Joyner, A.S.2
Potter, P.M.3
-
13
-
-
84868355027
-
The spliceosome as a target of novel antitumour drugs
-
Bonnal, S.; Vigevani, L.; Valcárcel, J. The spliceosome as a target of novel antitumour drugs Nat. Rev. Drug Discovery 2012, 11, 847-859
-
(2012)
Nat. Rev. Drug Discovery
, vol.11
, pp. 847-859
-
-
Bonnal, S.1
Vigevani, L.2
Valcárcel, J.3
-
14
-
-
34548095157
-
Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA
-
Kaida, D.; Motoyoshi, H.; Tashiro, E.; Nojima, T.; Hagiwara, M.; Ishigami, K.; Watanabe, H.; Kitahara, T.; Yoshida, T.; Nakajima, H.; Tani, T.; Horinouchi, S.; Yoshida, M. Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA Nat. Chem. Biol. 2007, 3, 576-583
-
(2007)
Nat. Chem. Biol.
, vol.3
, pp. 576-583
-
-
Kaida, D.1
Motoyoshi, H.2
Tashiro, E.3
Nojima, T.4
Hagiwara, M.5
Ishigami, K.6
Watanabe, H.7
Kitahara, T.8
Yoshida, T.9
Nakajima, H.10
Tani, T.11
Horinouchi, S.12
Yoshida, M.13
-
15
-
-
79955573435
-
Identification of SAP155 as the target of GEX1A (herboxidiene), an antitumor natural product
-
Hasegawa, M.; Miura, T.; Kuzuya, K.; Inoue, A.; Won, Ki, S.; Horinouchi, S.; Yoshida, T.; Kunoh, T.; Koseki, K.; Mino, K.; Sasaki, R.; Yoshida, M.; Mizukami, T. Identification of SAP155 as the target of GEX1A (herboxidiene), an antitumor natural product ACS Chem. Biol. 2010, 6, 229-233
-
(2010)
ACS Chem. Biol.
, vol.6
, pp. 229-233
-
-
Hasegawa, M.1
Miura, T.2
Kuzuya, K.3
Inoue, A.4
Won, K.S.5
Horinouchi, S.6
Yoshida, T.7
Kunoh, T.8
Koseki, K.9
Mino, K.10
Sasaki, R.11
Yoshida, M.12
Mizukami, T.13
-
16
-
-
84868347442
-
Structure of FD-895 revealed through total synthesis
-
Villa, R.; Mandel, A. L.; Jones, B. D.; La, C. J. J.; Burkart, M. D. Structure of FD-895 revealed through total synthesis Org. Lett. 2012, 14, 5396-5399
-
(2012)
Org. Lett.
, vol.14
, pp. 5396-5399
-
-
Villa, R.1
Mandel, A.L.2
Jones, B.D.3
La, C.J.J.4
Burkart, M.D.5
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