Evaluation of inhibitory effect of phlorotannins from Ecklonia cava on triglyceride accumulation in adipocyte

Journal of Agricultural and Food Chemistry

Volumn 61, Issue 36, 2013, Pages 8541-8547

  Kim, Haejin ^a   Kong, Chang Suk ^b   Lee, Jung Im ^a   Kim, Hojun ^a   Baek, Seungoh ^a   Seo, Youngwan ^a  

^a Korea Maritime University   (South Korea)

^b Silla University   (South Korea)

Author keywords

3T3 L1 cells; antiadipogenic components; Ecklonia cava; phlorotannin

Indexed keywords

3T3-L1 ADIPOCYTES; ANTIADIPOGENIC COMPONENTS; COMPARATIVE ANALYSIS; ECKLONIA CAVA; GLUCOSE CONSUMPTION; LIPID ACCUMULATIONS; METHANOLIC EXTRACTS; PHLOROTANNIN;

CHEMISTRY;

DIOXANE DERIVATIVE; ECKSTOLONOL; FUSED HETEROCYCLIC RINGS; GLUCOSE; TANNIN DERIVATIVE; TRIACYLGLYCEROL;

3T3 CELL LINE; ADIPOCYTE; ADIPOGENESIS; ANIMAL; ARTICLE; BROWN ALGA; CHEMISTRY; DRUG EFFECT; GENE EXPRESSION; GENETICS; METABOLISM; MOUSE;

3T3-L1 CELLS; ADIPOCYTES; ADIPOGENESIS; ANIMALS; DIOXANES; GENE EXPRESSION; GLUCOSE; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; MICE; PHAEOPHYTA; TANNINS; TRIGLYCERIDES;

EID: 84884215784     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf401454m     Document Type: Article

References (34)

1. Ali, M. S.; Jahangir, M.; Saleen, M.; Pervez, M.; Hameed, K. S.; Ahmad, V. U. Metabolites of marine algae collected from Karachi coasts of Arabian Sea Nat. Prod. Sci. 2000, 6, 61-65
2. Kong, C. S.; Kim, J. A.; Yoon, N. Y.; Kim, S. K. Induction of apoptosis by phloroglucinol derivative from Ecklonia cava in MCF-7 human breast cancer cells Food Chem. Toxicol. 2009, 47, 1653-1658
3. Kim, M. M.; Ta, Q. V.; Mendis, E.; Rajapakse, N.; Jung, W. K.; Byun, H. G.; Jeon, Y. J.; Kim, S. K. Phlorotannins in Ecklonia cava extract inhibit matrix metalloproteinase activity Life Sci. 2006, 79, 1436-1443
4. Kim, S. K.; Lee, D. Y.; Jung, W. K.; Kim, J. H.; Choi, I. H.; Park, S. G.; Seo, S. K.; Lee, S. W.; Lee, C. M.; Yea, S. S.; Choi, Y. H.; Choi, I. W. Effects of Ecklonia cava ethanolic extracts on airway hyperresponsiveness and inflammation in a murine asthma model: role of suppressor of cytokine signaling Biomed. Pharmacother. 2008, 62, 289-296
5. Kong, C. S.; Kim, J. A.; Ahn, B. N.; Kim, S K. Potential effect of phloroglucinol derivatives from Ecklonia cava on matrix metalloproteinase expression and the inflammatory profile in lipopolysaccharide-stimulated human THP-1 macrophages Fish. Sci. 2011, 77, 867-873
6. Vo, T. S.; Kim, J. A.; Wijesekara, I.; Kong, C. S.; Kim, S. K. Potent effect of brown algae (Ishige okamurae) on suppression of allergic inflammation in human basophilic KU812F cells Food Sci. Biotechnol. 2011, 20, 1227-1234
7. Kang, H. S.; Chung, H. Y.; Kim, J. Y.; Son, B. W.; Jung, H. A.; Choi, J. S. Inhibitory phlorotannins from the edible brown alga Ecklonia stolonifera on total reactive oxygen species (ROS) generation Arch. Pharm. Res. 2004, 27, 194-198
8. Shim, S. Y.; Quang-To, L.; Lee, S. H.; Kim, S. K. Ecklonia cava extract suppresses the high-affinity IgE receptor, FceRI expression Food Chem. Toxicol. 2009, 47, 555-560
9. Heo, S. J.; Jeon, Y. J. Radical scavenging capacity and cytoprotective effect of enzymatic digests of Ishige okamurae J Appl. Phycol. 2008, 20, 1087-1095
10. Eom, S. H.; Kim, Y. M.; Kim, S. K. Antimicrobial effect of phlorotannins from marine brown algae Food Chem. Toxicol. 2012, 50, 3251-3255
11. Yoshinyasu, F.; Iwao, M.; Ziunei, K.; Hideo, M.; Masaru, K.; Yasuo, N.; Masayuki, T.; Masamitsu, O. Eckols, novel phlorotannins with a dibenzo-p-dioxin skeleton prossessing inhibitory effect on α2-macroglobulin from the brown Ecklonia kurome okamura Chem. Lett. 1985, 14, 739-742
12. Yoshiyasu, F.; Mitsuaki, K.; Iwao, M.; Zyunei, K.; Hideo, M.; Yasuo, N.; Masayuki, T. Anti-plasmin inhibitor. VI. structure of phlorofucofuroeckol A, a novel phlorotannin with both dibenzo-1,4-dioxin and dibenzofuran elements, from Ecklonia kurome okamura Chem. Pharm. Bull. 1990, 38, 133-135
13. Kang, H. S.; Chung, H. Y.; Jung, J. H.; Son, B. W.; Choi, J. S. A new phlorotannin from the brown alga Ecklonia stolonifera Chem. Pharm. Bull. 2003, 51, 1012-1014
14. Yoshimasa, S.; Kohji, M.; Yasuhiro, Y.; Masashi, N.; Kazufumi, S.; Hirotaka, K.; Kunio, I.; Hideomi, A. Isolation of a new anti-allergic phlorotannin, phlorofucofuroeckol-B, from an edible alga Eisenia arborea Biosci., Biotechnol., Biochem. 2006, 70, 2807-2811
15. Li, Y.; Qian, Z. J.; Ryu, B. M.; Lee, S. H.; Kim, M. M.; Kim, S. K. Chemical components and its antioxidant properties in vitro: an edible marine brown alga Ecklonia cava Bioorg. Med. Chem. 2009, 17, 1963-1973
16. Kim, S. K.; Kong, C. S. Anti-adipogenic effect of dioxinodehydroeckol via AMPK activation in 3T3-L1 adipocytes Chem.-Biol. Interact. 2010, 186, 24-29
17. Kong, C. S.; Kim, J. A.; Ahn, B. N.; Vo, T. S.; Yoon, N. Y.; Kim, S. K. 1-(3′,5′-Dihydroxyphenoxy)-7-(2″,4″,6-trihydroxyphenoxy) -2,4,9-trihydroxydibenzo-1,4-dioxin inhibits adipocyte differentiation of 3T3-L1 fibroblasts Mar. Biotechnol. 2010, 12, 299-307
18. Kong, C. S.; Kim, J. A.; Eom, T. K.; Kim, S. K. Phosphorylated glucosamine inhibits adipogenesis in 3T3-L1 adipocytes J. Nutr. Biochem. 2010, 21, 438-443
19. Lee, W. J.; Koh, E. H.; Won, J. C.; Kim, M. S.; Park, J. Y.; Lee, K. U. Obesity: the role of hypothalamic AMP-activated protein kinase in body weight regulation Int. J. Biochem. Cell Biol. 2005, 37, 2254-2259
20. Jeon, T.; Hwang, S. G.; Hirai, S.; Matsui, T.; Yano, H.; Kawada, T.; Lim, B. O.; Park, D. K. Red yeast rice extracts suppress adipogenesis by down-regulating adipogenic transcription factors and gene expression in 3T3-L1 cells Life Sci. 2004, 17, 3195-3203
21. Lee, H. Y.; Kang, R. H.; Chung, S. I.; Cho, S. H.; Oh, D. J.; Yoon, Y. S. A study on the gene expression in Shikonin-induced inhibition of adipogenesis J. Life Sci. 2009, 19, 1637-1643
22. Rosen, E. D. The transcriptional basis of adipocyte development Prostaglandins, Leukotrienes Essent. Fatty Acids 2005, 73, 31-34
23. Chmurzyńska, A. The multigene family of fatty acid-binding proteins (FABPs): function, structure and polymorphism J. Appl. Genet. 2006, 47, 39-48
24. Smathers, R. L.; Petersen, D. R. The human fatty acid-binding protein family: evolutionary divergences and functions Hum. Genomics 2011, 5, 170-191
25. Weisiger, R. A. Cytosolic fatty acid binding proteins catalyze two distinct steps in intracellular transport of their ligands Mol. Cell. Biochem. 2002, 239, 35-43
26. Salas, V.; Noe, V.; Ciudad, C. J.; Romero, M. M.; Remesar, X.; Esteve, M. Short-term oleoyl-estrone treatment affects capacity to manage lipids in rat adipose tissue BMC Genom. 2007, 8, 292-297
27. Palmer, D. G.; Rutter, G. A.; Tavaré, J. M. Insulin-stimulated fatty acid synthase gene expression does not require increased sterol response element binding protein 1 transcription in primary adipocytes Biochem. Biophys. Res. Commun. 2002, 291, 439-443
28. Yang, Y. I.; Shin, H. C.; Kim, S. H.; Park, W. Y.; Lee, K. T.; Choi, J. H. 6,6′-Bieckol, isolated from marine alga Ecklonia cava, suppressed LPS-induced nitric oxide and PGE2 production and inflammatory cytokine expression in macrophages: the inhibition of NFκB Int. Immunopharmacol. 2012, 12, 510-517
29. Yoshinyasu, F.; Mitsuaki, K.; Iwao, M.; Zyunei, K.; Masaru, K.; Hideo, M.; Yasuo, N.; Masayuki, T. Structure of anti-plasma inhibitor, eckol, isolated from the brown alga Ecklonia Kurome okamura and inhibitory activities of its derivative on plasma inhibitors Chem. Pharm. Bull. 1989, 37, 349-353
30. Kim, S. K.; Lee, D. Y.; Jung, W. K.; Kim, J. H.; Choi, I. H.; Park, S. G.; Seo, S. K.; Lee, S. W.; Lee, C. M.; Yea, S. S.; Choi, Y. H.; Choi, I. W. Effects of Ecklonia cava ethanolic extracts on airway hyperresponsiveness and inflammation in a murine asthma model: role of suppressor of cytokine signaling Biomed. Pharmacother. 2008, 62, 289-296
31. Artan, M.; Li, Y.; Karadeniz, F.; Lee, S. H.; Kim, M. M.; Kim, S. K. Anti-HIV-1 activity of phloroglucinol derivative, 6,6′-bieckol, from Ecklonia cava Bioorg. Med. Chem. 2008, 16, 7921-7926
32. Le, Q. T.; Li, Y.; Qian, Z. J.; Kim, M. M.; Kim, S. K. Inhibitory effects of polyphenols isolated from marine alga Ecklonia cava on histamine release Process Biochem. 2009, 44, 168-176
33. Torres, M. A.; Barros, M. P.; Campos, S. C. G.; Rajamani, E. P. S.; Sayre, R. T.; Colepicolo, P. Biochemical biomarkers in algae and marine pollution: a review Ecotoxicol. Environ. Saf. 2008, 71, 1-15
34. Singh, I. P.; Bharate, S. B. Phloroglucinol compounds of natural origin Nat. Prod. Rep. 2006, 23, 558-591