Therapy-resistant tumor microvascular endothelial cells contribute to treatment failure in glioblastoma multiforme

Oncogene

Volumn 32, Issue 12, 2013, Pages 1539-1548

  Borovski, T ^a   Beke, P ^a   Van Tellingen, O ^b   Rodermond, H M ^a   Verhoeff, J J ^c   Lascano, V ^a   Daalhuisen, J B ^a   Medema, J P ^a   Sprick, M R ^d,e  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b ANTONI VAN LEEUWENHOEK HOSPITAL   (Netherlands)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

^d GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^e HI STEM GGmbH   (Germany)

Author keywords

cancer stem cells; glioblastoma multiforme; senescence; therapy resistance; tumor microenvironment; tumor microvasculature

Indexed keywords

CD133 ANTIGEN; TEMOZOLOMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER RADIOTHERAPY; CANCER RESISTANCE; CANCER STEM CELL; CELL AGING; CELL COUNT; CELL CYCLE ARREST; CELL DEATH; CELL DIFFERENTIATION; CELL INTERACTION; CELL VIABILITY; CLONOGENESIS; CONTROLLED STUDY; FEMALE; GLIOBLASTOMA; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; RADIATION EXPOSURE; RADIATION RESPONSE; SENESCENCE; THERAPY RESISTANCE; TREATMENT FAILURE; TREATMENT RESPONSE; TUMOR CELL; TUMOR MICROENVIRONMENT; TUMOR MICROVASCULAR ENDOTHELIAL CELL; TUMOR VASCULARIZATION; WESTERN BLOTTING;

ANIMALS; BRAIN NEOPLASMS; ENDOTHELIAL CELLS; FEMALE; GLIOBLASTOMA; HUMANS; MICE; NEOPLASTIC STEM CELLS; TREATMENT FAILURE;

MUS;

EID: 84884211499     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.172     Document Type: Article

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