Eccentric exercise-induced delayed-onset muscle soreness and changes in markers of muscle damage and inflammation

Exercise Immunology Review

Volumn 19, Issue , 2013, Pages 72-85

  Kanda, Kazue ^a   Sugama, Kaoru ^a   Hayashida, Harumi ^b   Sakuma, Jun ^b   Kawakami, Yasuo ^b   Miura, Shigeki ^c   Yoshioka, Hiroshi ^c   Mori, Yuichi ^c   Suzuki, Katsuhiko ^a,b  

^a TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

^b WASEDA UNIVERSITY   (Japan)

^c Mebiol Inc   (Japan)

Author keywords

Delayed onset muscle soreness; Eccentric exercise; Exercise induced muscle damage; Inflammatory mediators; Neutrophils

Indexed keywords

CALGRANULIN; COLONY STIMULATING FACTOR 1; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELOPEROXIDASE; MYOGLOBIN; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; CYTOKINE;

ADULT; ARTICLE; BLOOD SAMPLING; BODY WEIGHT; CELL MIGRATION; DELAYED ONSET MUSCLE SORENESS; ECCENTRIC EXERCISE; EXERCISE; EXTRACELLULAR MATRIX; HUMAN; INFLAMMATION; LEUKOCYTE COUNT; MALE; MUSCLE DISEASE; MUSCLE INJURY; MUSCLE TISSUE; NEUTROPHIL; NEUTROPHIL COUNT; PROSTAGLANDIN BLOOD LEVEL; PROSTAGLANDIN URINE LEVEL; RESPIRATORY BURST; URINALYSIS; VISUAL ANALOG SCALE; BLOOD; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOLOGY; METABOLISM; PAIN; PHYSIOLOGY; SKELETAL MUSCLE;

CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXERCISE; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; MALE; MUSCLE, SKELETAL; MYOGLOBIN; NEUTROPHILS; PAIN; YOUNG ADULT;

EID: 84884201351     PISSN: 10775552     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Cheung, K., P. Hume, and L. Maxwell. Delayed onset muscle soreness: Treatment strategies and performance factors. Sports Med. 33(2): 145-164. 2003.
2. Crameri, RM., P. Aagaard, K. Qvortrup, H. Langberg, J. Olesen, and M. Kjaer. Myofibre damage in human skeletal muscle: effects of electrical stimulation versus voluntary contraction. J. Physiol. 583(Pt1): 365-380. 2007.
3. Fielding, RA., TJ. Manfredi, W. Ding, MA. Fiatarone, WJ. Evans, and JG. Cannon. Acute phase response in exercise. III. Neutrophil and IL-1 beta accumulation in skeletal muscle. Am. J. Physiol. 265: 1(Pt2): R166-R172. 1993.
4. Fielding, RA., MA. Violan, L. Svetkey, LW. Abad, TJ. Manfredi, A. Cosmas, and J. Bean. Effects of prior exercise on eccentric exercise-induced neutrophilia and enzyme release. Med. Sci. Sports Exerc. 32(2): 359-364. 2000.
5. Gleeson, M., J. Almey, S. Brooks, R. Cave, A. Lewis, and H. Griffiths. Haematological and acute-phase responses associated with delayed-onset muscle soreness in humans. Eur. J. Appl. Physiol. Occup. Physiol. 71(2-3): 137-142. 1995.
6. Hansen, JB., L. Wilsgard, and B. Osterud. Biphasic changes in leukocytes induced by strenuous exercise. Eur. J. Appl. Physiol. Occup. Physiol. 62(3): 157-161. 1991.
7. Hasegawa, H., K. Suzuki, S. Nakaji, and K. Sugawara. Analysis and assessment of the capacity of neutrophils to produce reactive oxygen species in a 96-well microplate format using lucigenin- And luminol-dependent chemiluminescence. J. Immunol. Methods. 210(1): 1-10. 1997.
8. Hubal, MJ., TC. Chen, PD. Tompson, and PM. Clarkson. Inflammatory gene changes associated with the repeated-bout effect. Am. J. Physiol. Regul. Integr. Comp. Physiol. 294(5): R1628-1637. 2008.
9. Mahoney, DJ., A. Safdar, G. Parise, S. Melov, M. Fu, L. MacNeil, J. Kaczor, ET. Payne, and MA. Tarnopolsky. Gene expression profiling in human skeletal muscle during recovery from eccentric exercise. Am. J. Physiol. Regul. Integr. Comp. Physiol. 294(6): R1901-1910. 2008.
10. Malm, C., P. Nyberg, M. Engstrom, B. Sjodin, R. Lenkei, B. Ekblom, and I. Lundberg. Immunological changes in human skeletal muscle and blood after eccentric exercise and multiple biopsies. J. Physiol. 529(Pt1): 243-262. 2000.
11. Malm, C., TL. Sjodin, B. Sjoberg, R. Lenkei, P. Renstrom, IE. Lundberg, and B. Ekblom. Leukocytes, cytokines, growth factors and hormones in human skeletal muscle and blood after uphill or downhill running. J. Physiol. 556(Pt3): 983-1000. 2004.
12. Nieman, DC., SL. Nehlsen-Cannarella, OR. Fagoaga, DA. Henson, A. Utter, JM. Davis, F. Williams, and DE. Butterworth. Effects of mode and carbohydrate on the granulocyte and monocyte response to intensive, prolonged exercise. J. Appl. Physiol. 84(4): 1252-1259. 1998.
13. Nieman, DC., JM. Davis, DA. Henson, J. Walberg-Rankin, M. Shute, CL. Dumke, AC. Utter, DM. Vinci, JA. Carson, A. Brown, WJ. Lee, SR. McAnulty, and LS. McAnulty. Carbohydrate ingestion influences skeletal muscle cytokine mRNA and plasma cytokine levels after a 3-h run. J. Appl. Physiol. 94: 1917-1925. 2003.
14. Nosaka, K., M. Newton, and P. Sacco. Delayed-onset muscle soreness does not reflect the magnitude of eccentric exercise-induced muscle damage. Scand. J. Med. Sci. Sports. 12(6): 337-346. 2002.
15. Paulsen, G., HB. Benestad, I. Strom-Gundersen, L. Morkrid, KT. Lappegard, and T. Raastad. Delayed leukocytosis and cytokine response to high-force eccentric exercise. Med. Sci. Sports Exerc. 37(11): 1877-1883. 2005.
16. Peake, J., K. Nosaka, and K. Suzuki. Characterization of inflammatory responses to eccentric exercise in humans. Exerc. Immunol. Rev. 11: 64-85. 2005.
17. Pedersen, BK., A. Steensberg, P. Keller, C. Keller, C. Fischer, N. Hiscock, van G. Hall, P. Plomgaard, and M. Febbraio. Muscle-derived interleukin-6: lipolytic, antiinflammatory and immune regulatory effects. Eur. J. Physiol. 446(1): 9-16. 2003.
18. Pizza, FX., D. Cavender, A. Stockard, H. Baylies, and A. Beighle. Anti-inflammatory doses of ibuprofen: Effect on neutrophils and exercise-induced muscle injury. Int. J. Sports Med. 20(2): 98-102. 1999.
19. Ross, ML., SL. Halson, K. Suzuki, A. Garnham, JA. Hawley, D. Cameron-Smith, and JM. Peake. Cytokine responses to carbohydrate ingestion during recovery from exercise-induced muscle injury. J. Interferon Cytokine Res. 30(5): 329-337. 2010.
20. Saxton, JM., D. Claxton, E. Winter, and AG. Pockley. Peripheral blood leucocyte functional responses to acute eccentric exercise in humans are influenced by systemic stress, but not by exercise-induced muscle damage. Clin. Sci. (Lond). 104(1): 69-77. 2003.
21. Sayers, SP., and PM. Clarkson. Short-term immobilization after eccentric exercise. part II: Creatine kinase and myoglobin. Med. Sci. Sports Exerc. 35(5): 762-768. 2003.
22. Sudha, B., HN. Madhavan, G. Sitalakshmi, J. Malathi, S. Krishnakumar, Y. Mori, H. Yoshioka, and S. Abraham. Cultivation of human corneal limbal stem cells in mebiol gel?A thermo-reversible gelation polymer. Indian J. Med. Res. 124(6): 655-664. 2006.
23. Suzuki, K., S. Naganuma, M. Totsuka, KJ. Suzuki, M. Mochizuki, M. Shiraishi, S. Nakaji, and K. Sugawara. Effects of exhaustive endurance exercise and its one-week daily repetition on neutrophil count and functional status in untrained men. Int. J. Sports Med. 17(3): 205-212. 1996.
24. Suzuki K, M. Totsuka, S. Nakaji, M. Yamada, S. Kudoh, Q. Liu, K. Sugawara, K. Yamaya, and K. Sato. Endurance exercise causes interaction among stress hormones, cytokines, neutrophil dynamics, and muscle damage. J. Appl. Physiol. 87(4): 1360-1367. 1999.
25. Suzuki, K., M. Yamada, S. Kurakake, N. Okamura, K. Yamada, Q. Liu, S. Kudoh, K. Kowatari, S. Nakaji, and K. Sugawara. Circulating cytokines and hormones with immunosuppressive but neutrophil-priming potentials rise after endurance exercise in humans. Eur. J. Appl. Physiol. 81(4): 281-287. 2000.
26. Suzuki, K., S. Nakaji, M. Yamada, M. Totsuka, K. Sato, and K. Sugawara. Systemic inflammatory response to exhaustive exercise. Cytokine kinetics. Exerc. Immunol. Rev. 8: 6-48. 2002.
27. Suzuki, K., S. Ohno, Y. Suzuki, Y. Ohno, R. Okuyama, A. Aruga, M. Yamamoto, KO. Ishihara, T. Nozaki, S. Miura, H. Yosioka, and Y. Mori. Effect of green tea extract on reactive oxygen species produced by neutrophils from cancer patients. Anticancer Res. 32(6): 2369-2375. 2012.
28. Tidball, JG. Inflammatory cell response to acute muscle injury. Med. Sci. Sports Exerc. 27(7): 1022-1032. 1995.
29. Tidball, JG. Inflammatory processes in muscle injury and repair. Am. J. Physiol. Regul. Integr. Comp. Physiol. 288(2): R345-353. 2005.
30. Uchida, MC., K. Nosaka, C. Uqrinowitsch, A. Yamashita, E. Martines, AS. Moriscot, and MS. Aoki. Effect of bench press exercise intensity on muscle soreness and inflammatory mediators. J. Sports Sci. 27(5): 499-507. 2009.
31. Udani, JK, BB. Singh, VJ. Singh, and E. Sandoval. BounceBack capsules for reduction of DOMS after eccentric exercise: A randomized, double-blind, placebo-controlled, crossover pilot study. J. Int. Soc. Sports Nutr. 6: 14. 2009.
32. Willoughby, DS., B. McFarlin, and C. Bois. Interleukin-6 expression after repeated bouts of eccentric exercise. Int. J. Sports. Med. 24(1): 15-21. 2003.
33. Yu, JG., C. Malm, and LE. Thornell. Eccentric contractions leading to DOMS do not cause loss of desmin nor fibre necrosis in human muscle. Histochem. Cell Biol. 118(1): 29-34. 2002.