Milestones in Photocarcinogenesis

Journal of Investigative Dermatology

Volumn 133, Issue , 2013, Pages E13-E17

  Elmets, Craig A ^a   Athar, Mohammad ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DAMAGE; GENETICS; HUMAN; IMMUNOLOGY; PHOTOBIOLOGY; REVIEW; SKIN TUMOR; SQUAMOUS CELL CARCINOMA; ULTRAVIOLET RADIATION;

CARCINOMA, SQUAMOUS CELL; DNA DAMAGE; HUMANS; PHOTOBIOLOGY; SKIN NEOPLASMS; ULTRAVIOLET RAYS;

EID: 84884179128     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/skinbio.2013.179     Document Type: Article

References (59)

1. An, K.P., Athar, M., Tang, X., et al. Cyclooxygenase-2 expression in murine and human nonmelanoma skin cancers: implications for therapeutic approaches. Photochem Photobiol 76 (2002), 73–80.
2. Aszterbaum, M., Epstein, J., Oro, A., et al. Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice. Nat Med 5 (1999), 1285–1291.
3. Athar, M., Li, C., Tang, X., et al. Inhibition of smoothened signaling prevents ultraviolet B-induced basal cell carcinomas through regulation of Fas expression and apoptosis. Cancer Res 64 (2004), 7545–7552.
4. Bailey, H.H., Kim, K., Verma, A.K., et al. A randomized, double-blind, placebo-controlled phase 3 skin cancer prevention study of {alpha}-difluoromethylornithine in subjects with previous history of skin cancer. Cancer Prev Res 3 (2010), 35–47.
5. Bavinck, J.N., Tieben, L.M., Van der Woude, F.J., et al. Prevention of skin cancer and reduction of keratotic skin lesions during acitretin therapy in renal transplant recipients: a double-blind, placebo-controlled study. J Clin Oncol 13 (1995), 1933–1938.
6. Berg, R., van Kranen, H., Rebel, H., et al. Early p53 alterations in mouse skin carcinogenesis by UVB radiation: immunohistochemical detection of mutant p53 protein in clusters of preneoplastic epidermal cells. Proc Natl Acad Sci USA 93 (1996), 274–278.
7. Black, H.S., Herd, J.A., Goldberg, L.H., et al. Effect of a low-fat diet on the incidence of actinic keratosis. N Engl J Med 330 (1994), 1272–1275.
8. Blum, H.F., Carcinogenesis by Ultraviolet Light, 1959, Princeton University Press, Princeton.
9. Brash, D., Rudolph, J., Simon, J., et al. A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proc Natl Acad Sci USA 88 (1991), 10124–10128.
10. Butler, G.J., Neale, R., Green, A.C., et al. Nonsteroidal anti-inflammatory drugs and the risk of actinic keratoses and squamous cell cancers of the skin. J Am Acad Dermatol 53 (2005), 966–972.
11. Cleaver, J.E., Defective repair replication of DNA in xeroderma pigmentosum. Nature 218 (1968), 652–656.
12. Cleaver, J.E., Xeroderma pigmentosum: a human disease in which an initial stage of DNA repair is defective. Proc Natl Acad Sci USA 63 (1969), 428–435.
13. Cooper, K.D., Oberhelman, L., Hamilton, T.A., et al. UV exposure reduces immunization rates and promotes tolerance to epicutaneous antigens in humans, relationship to dose, CD1a-DR+ epidermal macrophage induction, and Langerhans cell depletion. Proc Natl Acad Sci USA 89 (1992), 8497–8501.
14. Couve-Privat, S., Bouadjar, B., Avril, M.F., et al. Significantly high levels of ultraviolet-specific mutations in the smoothened gene in basal cell carcinomas from DNA repair-deficient xeroderma pigmentosum patients. Cancer Res 62 (2002), 7186–7189.
15. Cowen, E.W., Nguyen, J.C., Miller, D.D., et al. Chronic phototoxicity and aggressive squamous cell carcinoma of the skin in children and adults during treatment with voriconazole. J Am Acad Dermatol 62 (2010), 31–37.
16. de Vries, A., van Oostrom, C.T., Hofhuis, F.M., et al. Increased susceptibility to ultraviolet-B and carcinogens of mice lacking the DNA excision repair gene XPA. Nature 377 (1995), 169–173.
17. Elmets, C.A., Bergstresser, P.R., Tigelaar, R.E., et al. Analysis of mechanism of unresponsiveness produced by haptens painted on skin exposed to low dose ultraviolet radiation. J Exp Med 158 (1983), 781–794.
18. Elmets, C.A., Viner, J.L., Pentland, A.P., et al. Chemoprevention of nonmelanoma skin cancer with celecoxib: a randomized, double-blind, placebo-controlled trial. J Natl Cancer Inst 102 (2010), 1835–1844.
19. Epstein, J.H., Epstein, W.L., Cocarcinogenic effect of ultraviolet light on DMBA tumor initiation in albino mice. J Invest Dermatol 39 (1962), 455–460.
20. Epstein, J.H., Roth, R.L., Experimental ultraviolet light carcinogenesis: a study of croton oil promotion. J Invest Dermatol 50 (1968), 387–389.
21. Findlay, G.M., Ultra-violet light and skin cancer. Lancet ii (1928), 1070–1073.
22. Fischer, S., Lo, H., Gordon, G., et al. Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, and indomethacin against ultraviolet light-induced skin carcinogenesis. Mol Carcinog 25 (1999), 231–240.
23. Freeman, R.G., Data on the action spectrum for ultraviolet carcinogenesis. J Natl Cancer Inst 55 (1975), 1119–1122.
24. Gailani, M.R., Stahle-Backdahl, M., Leffell, D.J., et al. The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas. Nat Genet 14 (1996), 78–81.
25. Green, A., Williams, G., Neale, R., et al. Daily sunscreen application and betacarotene supplementation in prevention of basal-cell and squamous-cell carcinomas of the skin: a randomised controlled trial. Lancet 354 (1999), 723–729.
26. Hartevelt, M.M., Bouwes Bavinck, J.N., Kootte, A.M., et al. Incidence of skin cancer after renal transplantation in the Netherlands. Transplantation 49 (1990), 506–509.
27. Hillebrand, G., Winslow, M., Benzinger, M., et al. Acute and chronic ultraviolet radiation induction of epidermal ornithine decarboxylase activity in hairless mice. Cancer Res 50 (1990), 1580–1584.
28. Hoxtell, E.O., Mandel, J.S., Murray, S.S., et al. Incidence of skin cancer after renal transplantation. Arch Dermatol 113 (1977), 436–438.
29. Johnson, R.L., Rothman, A.L., Xie, J., et al. Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 272 (1996), 1668–1671.
30. Katiyar, S.K., Treatment of silymarin, a plant flavonoid, prevents ultraviolet light-induced immune suppression and oxidative stress in mouse skin. Int J Oncol 21 (2002), 1213–1222.
31. Kraemer, K.H., DiGiovanna, J.J., Moshell, A.N., et al. Prevention of skin cancer in xeroderma pigmentosum with the use of oral isotretinoin. N Engl J Med 318 (1988), 1633–1637.
32. Kripke, M.L., Antigenicity of murine skin tumors induced by ultraviolet light. J Natl Cancer Inst 53 (1974), 1333–1336.
33. Loser, K., Apelt, J., Voskort, M., et al. IL-10 Controls Ultraviolet-Induced Carcinogenesis in Mice. J Immunol 179 (2007), 365–371.
34. Lowe, N., Verma, A.K., Boutwell, R.K., Ultraviolet light induces epidermal ornithine decarboxylase activity. J Invest Dermatol 71 (1978), 417–418.
35. Nijsten, T.E., Stern, R.S., Oral retinoid use reduces cutaneous squamous cell carcinoma risk in patients with psoriasis treated with psoralen-UVA: a nested cohort study. J Am Acad Dermatol 49 (2003), 644–650.
36. O'Donovan, P., Perrett, C.M., Zhang, X., et al. Azathioprine and UVA light generate mutagenic oxidative DNA damage. Science 309 (2005), 1871–1874.
37. Pentland, A., Schoggins, J., Scott, G., et al. Reduction of UV-induced skin tumors in hairless mice by selective COX-2 inhibition. Carcinogenesis 20 (1999), 1939–1944.
38. Rogers, H.W., Weinstock, M.A., Harris, A.R., et al. Incidence estimate of nonmelanoma skin cancer in the United States. Arch Dermatol 146 (2010), 283–287.
39. Schwarz, A., Grabbe, S., Aragane, Y., et al. Interleukin-12 prevents ultraviolet B-induced local immunosuppression and overcomes UVB-induced tolerance. J Invest Dermatol 106 (1996), 1187–1191.
40. Setlow, R.B., Setlow, J.K., Evidence that ultraviolet-induced thymine dimers in DNA cause biological damage. Proc Natl Acad Sci USA 48 (1962), 1250–1257.
41. Sharma, S.D., Katiyar, S.K., Dietary grape seed proanthocyanidins inhibit UVB-induced cyclooxygenase-2 expression and other inflammatory mediators in UVB-exposed skin and skin tumors of SKH-1 hairless mice. Pharm Res 27 (2010), 1092–1102.
42. Shreeder, V., Giese, T., Sung, V.W., et al. A cytokine cascade including prostaglandin E2, IL-4, and IL-10 is responsible for systemic immune suppression. J Immunol 160 (1998), 3783–3789.
43. Sterenborg, H.J., van der Leun, J.C., Tumorigenesis by a long wavelength UV-A source. Photochem Photobiol 51 (1990), 325–330.
44. Stern, R.S., Laird, N., Melski, J., et al. Cutaneous Squamous-Cell Carcinoma in Patients Treated with PUVA. N Engl J Med 310 (1984), 1156–1161.
45. Strickland, P.T., Photocarcinogenesis by near-ultraviolet (UVA) radiation in Sencar mice. J Invest Dermatol 87 (1986), 272–275.
46. Tang, J.Y., Aszterbaum, M., Athar, M., et al. Basal cell carcinoma chemoprevention with nonsteroidal anti-inflammatory drugs in genetically predisposed PTCH1+/- humans and mice. Cancer Prev Res 3 (2010), 25–34.
47. Tang, J.Y., Mackay-Wiggan, J.M., Aszterbaum, M., et al. Inhibiting the hedgehog pathway in patients with the basal-cell nevus syndrome. N Engl J Med 366 (2012), 2180–2188.
48. Tang, X., Kim, A.L., Feith, D.J., et al. Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/- mice. J Clin Invest 113 (2004), 867–875.
49. Tang, X., Zhu, Y., Han, L., et al. CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice. J Clin Invest 117 (2007), 3753–3764.
50. Thompson, S.C., Jolley, D., Marks, R., Reduction of Solar Keratoses by Regular Sunscreen Use. N Engl J Med 329 (1993), 1147–1151.
51. Toews, G.B., Bergstresser, P.R., Streilein, J.W., et al. Epidermal Langerhans cell density determines whether contact hypersensitivity or unresponsiveness follows skin painting with DNFB. J Immunol 124 (1980), 445–453.
52. Unna, P.G., Die Histopathologie der Hautkrankheiten. Hirschwald: Berlin, 1894.
53. van der Pols, J.C., Williams, G.M., Pandeya, N., et al. Prolonged prevention of squamous cell carcinoma of the skin by regular sunscreen use. Cancer Epidemiol Biomarkers Prev 15 (2006), 2546–2548.
54. Von Hoff, D.D., LoRusso, P.M., Rudin, C.M., et al. Inhibition of the hedgehog pathway in advanced basal-cell carcinoma. N Engl J Med 361 (2009), 1164–1172.
55. Wang, Z., Agarwal, R., Bickers, D., et al. Protection against ultraviolet B radiation-induced photocarcinogenesis in hairless mice by green tea polyphenols. Carcinogenesis 12 (1991), 1527–1530.
56. Yarosh, D., Klein, J., O'Connor, A., et al. Effect of topically applied T4 endonuclease V in liposomes on skin cancer in xeroderma pigmentosum: a randomised study. Lancet 357 (2001), 926–929.
57. Yoshikawa, T., Rae, V., Bruins-Slot, W., et al. Susceptibility to effects of UVB radiation on induction of contact hypersensitivity as a risk factor for skin cancer in man. J Invest Dermatol 95 (1990), 530–536.
58. Zhang, H., Ping, X.L., Lee, P.K., et al. Role of PTCH and p53 genes in early-onset basal cell carcinoma. Am J Pathol 158 (2001), 381–385.
59. Ziegler, A., Jonason, A., Leffell, D., et al. Sunburn and p53 in the onset of skin cancer. Nature 372 (1994), 773–776.