Development of intravenous lipid emulsion of vinorelbine based on drug-phospholipid complex technique

International Journal of Pharmaceutics

Volumn 454, Issue 1, 2013, Pages 472-477

  Li, Yanzhen ^a   Jin, Wenxian ^a   Yan, Hui ^a   Liu, Huan ^a   Wang, Chenggang ^a  

^a TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH   (China)

Author keywords

Antitumor activity; Drug phospholipid complex; Injection irritation; Vinorelbine

Indexed keywords

LIPID EMULSION; NAVELBINE; PHOSPHATIDYLCHOLINE; PHOSPHOLIPID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG EFFICACY; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; ENCAPSULATION; HUMAN; HUMAN CELL; LIPOPHILICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RABBIT;

EID: 84884163199     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.06.032     Document Type: Article

References (19)

1. Andrew, X.C., 2006. Compositions for Delivering Highly Water Soluble Drugs, US, US2006008480A1.
2. Bivins, B.A., Rapp, R.P., Record, K., Meng, H.C., Griffen, W.O., 1980. Parenteral safflower oil emulsion (liposyn10%): safety and effectiveness in treating or preventing essential fatty acid deficiency in surgical patients. Ann. Surg. 191, 307-315. (Pubitemid 10184244)
3. Bonneterre, J., Chevalier, B., Focan, C., Mauriac, L., Piccart, M., 2001. Phase I and pharmacokinetic study of weekly oral therapy with vinorelbine in patients with advanced breast cancer (ABC). Ann. Oncol. 12, 1683-1691. (Pubitemid 34105657)
4. Carpentier, Y.A., Hacquebard, M., 2006. Intravenous lipid emulsions to deliver omega 3 fatty acids. Prostaglandins Leukot. Essent. Fatty Acids 75, 145-148. (Pubitemid 44292519)
5. Driscoll, D.F., Bacon, M.N., Bistrian, B.R., 2000. Physicochemical stability of two types of intravenous lipid emulsion as total nutrient admixtures. JPEN J. Parenter Enteral. Nutr. 24, 15-22. (Pubitemid 30027149)
6. Fukui, H., Koike, T., Nakagawa, T., Saheki, A., Sonoke, S., Tomii, Y., Seki, J., 2003. Comparison of LNS-AmB, a novel low-dose formulation of amphotericin B with lipid nano-sphere (LNS), with commercial lipid-based formulations. Int. J. Pharm. 267, 101-112. (Pubitemid 37352954)
7. Hansrani, P.K., Davis, S.S., Groves, M.J., 1983. The preparation and properties of sterile intravenous emulsions. J. Parenter. Sci. Technol. 37, 145-150. (Pubitemid 13042207)
8. Jumaa, M., Müller, B.W., 1998. The effect of oil components and homogenization conditions on the physicochemical properties and stability of parenteral fat emulsions. Int. J. Pharm. 163, 81-89. (Pubitemid 28162622)
9. Maiti, K., Mukherjee, K., Gantait, A., Saha, B.P., Mukherjee, P.K., 2007. Curcumin-phospholipid complex: preparation, therapeutic evaluation and pharmacokinetic study in rats. Int. J. Pharm. 330, 155-163.
10. Mare, M., Maisano, R., Caristi, N., Adamo, V., Altavilla, G., Carboni, R., Munao, S., La Torre, F., 2003. Venous damage prevention by defibrotide in vinorelbine-treated patients. Support. Care Cancer 11, 593-596. (Pubitemid 37152631)
11. Marquet, P., Lachatre, G., Debord, J., Eichler, B., Bonnaud, F., Nicot, G., 1992. Pharmacokinetics of vinorelbine in man. Eur. J. Clin. Pharmacol. 42, 545-547.
12. Peng, Q., Zhang, Z.R., Gong, T., Chen, G.Q., Sun, X., 2012. A rapid-acting, long-acting insulin formulation based on a phospholipid complex loaded PHBHHx nanoparticles. Biomaterials 33, 1583-1588.
13. Rabinovich-Guilatt, L., Dubernet, C., Gaudin, K., Lambert, G., Couvreur, P., Chaminade, P., 2005. Phospholipid hydrolysis in a pharmaceutical emulsion assessed by physicochemical parameters and a new analytical method. Eur. J. Pharm. Biopharm. 61, 69-76. (Pubitemid 41096690)
14. Su, M., Zhao, M., Luo, Y., Lin, X., Xu, L., He, H., Xu, H., Tang, X., 2011. Evaluation of the efficacy, toxicity and safety of vinorelbine incorporated in a lipid emulsion. Int. J. Pharm. 411, 188-196.
15. Yanyu, X., Yunmei, S., Zhipeng, C., Qineng, P., 2006. The preparation of silybin-phospholipid complex and the study on its pharmacokinetics in rats. Int. J. Pharm. 307, 77-82. (Pubitemid 41773254)
16. You, J., Wan, F., de Cui, F., Sun, Y., Du, Y.Z., Hu, F.Q., 2007. Preparation and characteristic of vinorelbine bitartrate-loaded solid lipid nanoparticles. Int. J. Pharm. 343, 270-276. (Pubitemid 47321031)
17. Zhang, H., Wang, Z.Y., Gong, W., Li, Z.P., Mei, X.G., Lv, W.L., 2011. Development and characteristics of temperature-sensitive liposomes for vinorelbine bitartrate. Int. J. Pharm. 414, 56-62.
18. Zhang, H.Y., Tang, X., Li, H.Y., Liu, X.L., 2008. A lipid microsphere vehicle for vinorelbine: stability, safety and pharmacokinetics. Int. J. Pharm. 348, 70-79. (Pubitemid 350266241)
19. Zhang, X., Yan, C., Cai, Z., Zhang, L., 2005. Stabilized oil-in-water emulsion of vinca alkaloids for vein and production thereof, china, 200510038178.6.