Reduced plakoglobin immunoreactivity in arrhythmogenic cardiomyopathy: Methodological considerations

Cardiovascular Pathology

Volumn 22, Issue 5, 2013, Pages 314-318

  Noorman, Maartje ^a,b   Hakim, Sara ^a   Asimaki, Angeliki ^c   Vreeker, Arnold ^a   Van Rijen, Harold V M ^a   Van Der Heyden, Marcel A G ^a   De Jonge, Nicolaas ^a   De Weger, Roel A ^a   Hauer, Richard N W ^a,b   Saffitz, Jeffrey E ^c   Van Veen, Toon A B ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Arrhythmogenic cardiomyopathy; Biopsy; Immunohistochemistry; Plakoglobin

Indexed keywords

FORMALDEHYDE; JUNCTIONAL PLAKOGLOBIN; NERVE CELL ADHESION MOLECULE; PLAKOGLOBIN; PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

ARRHYTHMOGENESIS; ARRHYTHMOGENIC CARDIOMYOPATHY; ARTICLE; AUTOPSY; CARDIOMYOPATHY; CLINICAL ARTICLE; CONTROLLED STUDY; DILUTION; HEART MUSCLE BIOPSY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; PRIORITY JOURNAL; TISSUE PRESERVATION;

ARRHYTHMOGENIC CARDIOMYOPATHY; BIOPSY; IMMUNOHISTOCHEMISTRY; PLAKOGLOBIN;

ANTIBODIES; ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; DESMOPLAKINS; DESMOSOMES; DOUBLE-BLIND METHOD; HUMANS; IMMUNOHISTOCHEMISTRY; TISSUE PRESERVATION;

EID: 84884153769     PISSN: 10548807     EISSN: 18791336     Source Type: Journal    
DOI: 10.1016/j.carpath.2013.04.002     Document Type: Article

References (19)

1. G Thiene, A Nava, D Corrado, L Rossi, and N Pennelli Right ventricular cardiomyopathy and sudden death in young people N Engl J Med 318 1988 129 133
2. B Gerull, A Heuser, T Wichter, M Paul, CT Basson, DA McDermott, BB Lerman, SM Markowitz, PT Ellinor, CA MacRae, S Peters, KS Grossmann, J Drenckhahn, B Michely, S Sasse-Klaassen, W Birchmeier, R Dietz, G Breithardt, E Schulze-Bahr, and L Thierfelder Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy Nat Genet 36 2004 1162 1164
3. JP van Tintelen, MM Entius, ZA Bhuiyan, R Jongbloed, AC Wiesfeld, AA Wilde, J van der Smagt, LG Boven, MM Mannens, IM van Langen, RM Hofstra, LC Otterspoor, PA Doevendans, LM Rodriguez, IC van Gelder, and RN Hauer Plakophilin-2 mutations are the major determinant of familial arrhythmogenic right ventricular dysplasia/cardiomyopathy Circulation 113 2006 1650 1658
4. A Rampazzo, A Nava, S Malacrida, G Beffagna, B Bauce, V Rossi, R Zimbello, B Simionati, C Basso, G Thiene, JA Towbin, and GA Danieli Mutation in human desmoplakin domain binding to plakoglobin causes a dominant form of arrhythmogenic right ventricular cardiomyopathy Am J Hum Genet 71 2002 1200 1206
5. K Pilichou, A Nava, C Basso, G Beffagna, B Bauce, A Lorenzon, G Frigo, A Vettori, M Valente, J Towbin, G Thiene, GA Danieli, and A Rampazzo Mutations in desmoglein-2 gene are associated with arrhythmogenic right ventricular cardiomyopathy Circulation 113 2006 1171 1179
6. P Syrris, D Ward, A Evans, A Asimaki, E Gandjbakhch, S Sen-Chowdhry, and WJ McKenna Arrhythmogenic right ventricular dysplasia/cardiomyopathy associated with mutations in the desmosomal gene desmocollin-2 Am J Hum Genet 79 2006 978 984
7. A Heuser, ER Plovie, PT Ellinor, KS Grossmann, JT Shin, T Wichter, CT Basson, BB Lerman, S Sasse-Klaassen, L Thierfelder, CA MacRae, and B Gerull Mutant desmocollin-2 causes arrhythmogenic right ventricular cardiomyopathy Am J Hum Genet 79 2006 1081 1088
8. A Asimaki, P Syrris, T Wichter, P Matthias, JE Saffitz, and WJ McKenna A novel dominant mutation in plakoglobin causes arrhythmogenic right ventricular cardiomyopathy Am J Hum Genet 81 2007 964 973
9. M Noorman, MA van der Heyden, TA van Veen, MG Cox, RN Hauer, JM de Bakker, and HV van Rijen Cardiac cell-cell junctions in health and disease: electrical versus mechanical coupling J Mol Cell Cardiol 47 2009 23 31
10. WJ McKenna, G Thiene, A Nava, F Fontaliran, C Blomstrom-Lundqvist, G Fontaine, and F Camerini Diagnosis of arrhythmogenic right ventricular dysplasia/cardiomyopathy. Task force of the working group myocardial and pericardial disease of the european society of cardiology and of the scientific council on cardiomyopathies of the international society and federation of cardiology Br Heart J 71 1994 215 218
11. FI Marcus, WJ McKenna, D Sherrill, C Basso, B Bauce, DA Bluemke, H Calkins, D Corrado, MG Cox, JP Daubert, G Fontaine, K Gear, R Hauer, A Nava, MH Picard, N Protonotarios, JE Saffitz, DM Sanborn, JS Steinberg, H Tandri, G Thiene, JA Towbin, A Tsatsopoulou, T Wichter, and W Zareba Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia: proposed modification of the task force criteria Circulation 121 2010 1533 1541
12. MG Cox, JJ van der Smagt, M Noorman, AC Wiesfeld, PG Volders, IM van Langen, DE Atsma, D Dooijes, AC Houweling, P Loh, L Jordaens, Y Arens, MJ Cramer, PA Doevendans, JP van Tintelen, AA Wilde, and RN Hauer Arrhythmogenic right ventricular dysplasia/cardiomyopathy diagnostic task force criteria: impact of new task force criteria Circ Arrhythm Electrophysiol 3 2010 126 133
13. C Basso, F Ronco, F Marcus, A Abudureheman, S Rizzo, AC Frigo, B Bauce, F Maddalena, A Nava, D Corrado, F Grigoletto, and G Thiene Quantitative assessment of endomyocardial biopsy in arrhythmogenic right ventricular cardiomyopathy/dysplasia: an in vitro validation of diagnostic criteria Eur Heart J 29 2008 2760 2771
14. A Asimaki, H Tandri, H Huang, MK Halushka, S Gautam, C Basso, G Thiene, A Tsatsopoulou, N Protonotarios, WJ McKenna, H Calkins, and JE Saffitz A new diagnostic test for arrhythmogenic right ventricular cardiomyopathy N Engl J Med 360 2009 1075 1084
15. JR Winterfield, J Lee, A Asimaki, K Inada, PT Ellinor, UB Tedrow, J Saffitz, and WG Stevenson Plakoglobin abnormalities and arrhythmogenesis in idiopathic cardiomyopathies Heart Rhythm 7 2010 S113
16. A Asimaki, H Tandri, ER Duffy, JR Winterfield, S Mackey-Bojack, MM Picken, LT Cooper, DJ Wilber, FI Marcus, C Basso, G Thiene, A Tsatsopoulou, N Protonotarios, WG Stevenson, WJ McKenna, S Gautam, DG Remick, H Calkins, and JE Saffitz Altered desmosomal proteins in granulomatous myocarditis and potential pathogenic links to arrhythmogenic right ventricular cardiomyopathy Circ Arrhythm Electrophysiol 4 2011 743 752
17. M Noorman, S Hakim, E Kessler, J Groeneweg, M Gpj Cox, A Asimaki, HV van Rijen, L van Stuijvenberg, H Chkourko, MA van der Heyden, MA Vos, N de Jonge, JJ van der Smagt, D Dooijes, A Vink, RA de Weger, A Varro, JM de Bakker, JE Saffitz, TJ Hund, PJ Mohler, M Delmar, RN Hauer, and TA van Veen Remodeling of the cardiac sodium channel, connexin43 and plakoglobin at the intercalated disk in patients with arrhythmogenic cardiomyopathy Heart Rhythm 2012 in press (doi:pii: S1547-5271(12)01369-0. 10.1016/j.hrthm.2012.11.018.)
18. F Bajanca, M Luz, MJ Duxson, and S Thorsteinsdottir Integrins in the mouse myotome: developmental changes and differences between the epaxial and hypaxial lineage Dev Dyn 231 2004 402 415
19. J Munkholm, AH Christensen, JH Svendsen, and CB Andersen Usefulness of immunostaining for plakoglobin as a diagnostic marker of arrhythmogenic right ventricular cardiomyopathy Am J Cardiol 109 2012 272 275