Selective serotonin 2A receptor antagonism attenuates the effects of amphetamine on arousal and dopamine overflow in non-human primates

Journal of Sleep Research

Volumn 22, Issue 5, 2013, Pages 581-588

  Murnane, Kevin S ^a   Andersen, Monica L ^a,b   Rice, Kenner C ^c   Howell, Leonard L ^a,d  

^a EMORY UNIVERSITY   (United States)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

5 HT2A; Amphetamine; Arousal; M100907; Microdialysis; Rhesus monkeys

Indexed keywords

AMPHETAMINE; DOPAMINE RECEPTOR; SEROTONIN 2A RECEPTOR; VOLINANSERIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; AROUSAL; ARTICLE; CAUDATE NUCLEUS; CIRCADIAN RHYTHM; DOPAMINE BRAIN LEVEL; DOPAMINE RELEASE; DOPAMINERGIC NERVE CELL; FEMALE; IN VIVO STUDY; MICRODIALYSIS; NEUROTRANSMISSION; NONHUMAN; PRIMATE; PRIORITY JOURNAL; RHESUS MONKEY; SLEEP; SLEEP TIME; WAKEFULNESS;

AMPHETAMINE; ANIMALS; AROUSAL; CAUDATE NUCLEUS; CENTRAL NERVOUS SYSTEM STIMULANTS; CIRCADIAN RHYTHM; DOPAMINE; DOPAMINE UPTAKE INHIBITORS; FEMALE; FLUOROBENZENES; MACACA MULATTA; MICRODIALYSIS; PIPERIDINES; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTORS, DOPAMINE; SEROTONIN 5-HT2 RECEPTOR ANTAGONISTS; SLEEP; TELEMETRY; WAKEFULNESS;

EID: 84884146753     PISSN: 09621105     EISSN: 13652869     Source Type: Journal    
DOI: 10.1111/jsr.12045     Document Type: Article

References (28)

1. Andersen, M. L., Kessler, E., Murnane, K. S., McClung, J. C., Tufik, S., Howell, L. L. Dopamine transporter-related effects of modafinil in rhesus monkeys. Psychopharmacology, 2010, 210: 439-448.
2. Banks, M. L., Andersen, M. L., Murnane, K. S., Meyer, R. C., Howell, L. L. Behavioral and neurochemical effects of cocaine and diphenhydramine combinations in rhesus monkeys. Psychopharmacology, 2009, 205: 467-474.
3. Barrett, C. E., Noble, P., Hanson, E., Pine, D. S., Winslow, J. T., Nelson, E. E. Early adverse rearing experiences alter sleep-wake patterns and plasma cortisol levels in juvenile rhesus monkeys. Psychoneuroendocrinology, 2009, 34: 1029-1040.
4. Boutrel, B., Koob, G. F. What keeps us awake: the neuropharmacology of stimulants and wakefulness-promoting medications. Sleep, 2004, 27: 1181-1194.
5. Dahan, L., Astier, B., Vautrelle, N., Urbain, N., Kocsis, B., Chouvet, G. Prominent burst firing of dopaminergic neurons in the ventral tegmental area during paradoxical sleep. Neuropsychopharmacology, 2007, 32: 1232-1241.
6. Emiliano, A. B., Fudge, J. L. From galactorrhea to osteopenia: rethinking serotonin-prolactin interactions. Neuropsychopharmacology, 2004, 29: 833-846.
7. Fantegrossi, W. E., Ullrich, T., Rice, K. C., Woods, J. H., Winger, G. 3, 4-Methylenedioxymethamphetamine (MDMA, 'ecstasy') and its stereoisomers as reinforcers in rhesus monkeys: serotonergic involvement. Psychopharmacology, 2002, 161: 356-364.
8. Fantegrossi, W. E., Bauzo, R. M., Manvich, D. M. et al. Role of dopamine transporters in the behavioral effects of 3, 4-methylenedioxymethamphetamine (MDMA) in nonhuman primates. Psychopharmacology, 2009, 205: 337-347.
9. Isaac, S. O., Berridge, C. W. Wake-promoting actions of dopamine D1 and D2 receptor stimulation. J. Pharmacol. Exp. Ther., 2003, 307: 386-394.
10. Jones, B. E., Bobillier, P., Pin, C., Jouvet, M. The effect of lesions of catecholamine-containing neurons upon monoamine content of the brain and EEG and behavioral waking in the cat. Brain Res., 1973, 58: 157-177.
11. Jones, B. E., Harper, S. T., Halaris, A. E. Effects of locus coeruleus lesions upon cerebral monoamine content, sleep-wakefulness states and the response to amphetamine in the cat. Brain Res., 1977, 124: 473-496.
12. Kanbayashi, T., Honda, K., Kodama, T., Mignot, E., Nishino, S. Implication of dopaminergic mechanisms in the wake-promoting effects of amphetamine: a study of D- and L-derivatives in canine narcolepsy. Neuroscience, 2000, 99: 651-659.
13. Kushida, C. A., Chang, A., Gadkary, C., Guilleminault, C., Carrillo, O., Dement, W. C. Comparison of actigraphic, polysomnographic, and subjective assessment of sleep parameters in sleep-disordered patients. Sleep Med., 2001, 2: 389-396.
14. McMahon, L. R., Cunningham, K. A. Antagonism of 5-hydroxytryptamine(2a) receptors attenuates the behavioral effects of cocaine in rats. J. Pharmacol. Exp. Ther., 2001, 297: 357-363.
15. Miller, J. D., Farber, J., Gatz, P., Roffwarg, H., German, D. C. Activity of mesencephalic dopamine and non-dopamine neurons across stages of sleep and walking in the rat. Brain Res., 1983, 273: 133-141.
16. Murnane, K. S., Howell, L. L. Neuroimaging and drug taking in primates. Psychopharmacology, 2011, 216: 153-171.
17. Murnane, K. S., Fantegrossi, W. E., Godfrey, J. R., Banks, M. L., Howell, L. L. Endocrine and neurochemical effects of 3, 4-methylenedioxymethamphetamine and its stereoisomers in rhesus monkeys. J. Pharmacol. Exp. Ther., 2010, 334: 642-650.
18. Nishino, S., Mao, J., Sampathkumaran, R., Shelton, J. Increased dopaminergic transmission mediates the wake-promoting effects of CNS stimulants. Sleep Res. Online, 1998, 1: 49-61.
19. Papailiou, A., Sullivan, E., Cameron, J. L. Behaviors in rhesus monkeys (Macaca mulatta) associated with activity counts measured by accelerometer. Am. J. Primatol., 2008, 70: 185-190.
20. Paus, S., Brecht, H. M., Koster, J., Seeger, G., Klockgether, T., Wullner, U. Sleep attacks, daytime sleepiness, and dopamine agonists in Parkinson's disease. Mov. Disord., 2003, 18: 659-667.
21. Porras, G., Di Matteo, V., Fracasso, C. et al. 5-HT2A and 5-HT2C/2B receptor subtypes modulate dopamine release induced in vivo by amphetamine and morphine in both the rat nucleus accumbens and striatum. Neuropsychopharmacology, 2002, 26: 311-324.
22. Ritz, M. C., Boja, J. W., George, F. R., Kuhar, M. J. Cocaine binding sites related to drug self-administration. NIDA Res. Mono., 1989, 95: 239-246.
23. Rye, D. B. Modulation of normal and pathologic motoneuron activity during sleep: insights from the neurology clinic, Parkinson's disease, and comments on parkinsonian-related sleepiness. Sleep Med., 2002, 3(Suppl): S43-S49.
24. Sadeh, A., Hauri, P. J., Kripke, D. F., Lavie, P. The role of actigraphy in the evaluation of sleep disorders. Sleep, 1995, 18: 288-302.
25. 2 receptor antagonist MDL 100907 as a putative atypical antipsychotic: behavioral, electrophysiological and neurochemical studies. J. Pharmacol. Exp. Ther., 1993, 266: 684-691.
26. Steinfels, G. F., Heym, J., Strecker, R. E., Jacobs, B. L. Behavioral correlates of dopaminergic unit activity in freely moving cats. Brain Res., 1983, 258: 217-228.
27. Wilcox, K. M., Lindsey, K. P., Votaw, J. R. et al. Self-administration of cocaine and the cocaine analog RTI-113: relationship to dopamine transporter occupancy determined by PET neuroimaging in rhesus monkeys. Synapse, 2002, 43: 78-85.
28. Wisor, J. P., Nishino, S., Sora, I., Uhl, G. H., Mignot, E., Edgar, D. M. Dopaminergic role in stimulant-induced wakefulness. J. Neurosci., 2001, 21: 1787-1794.