HPA system activity in alexithymia: A cortisol awakening response study

Psychoneuroendocrinology

Volumn 38, Issue 10, 2013, Pages 2121-2126

  Alkan Härtwig, Elif ^a,b   Aust, Sabine ^a,b   Heuser, Isabella ^a,b  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Alexithymia; Cortisol; Cortisol awakening response; HPA; Personality; Stress

Indexed keywords

HYDROCORTISONE;

ADULT; ALEXITHYMIA; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; CORTISOL AWAKENING RESPONSE; DISEASE ASSOCIATION; ENDOCRINE FUNCTION; FEMALE; FUNCTIONAL ASSESSMENT; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INTERPERSONAL COMMUNICATION; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RATING SCALE; SCORING SYSTEM; SOCIAL INTERACTION; STRESS; SYNDROME DELINEATION;

ALEXITHYMIA; CORTISOL; CORTISOL AWAKENING RESPONSE; HPA; PERSONALITY; STRESS;

ADULT; AFFECTIVE SYMPTOMS; CASE-CONTROL STUDIES; HUMANS; HYDROCORTISONE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; INTERPERSONAL RELATIONS; MIDDLE AGED; PITUITARY-ADRENAL SYSTEM; SALIVA; WAKEFULNESS; YOUNG ADULT;

EID: 84883874042     PISSN: 03064530     EISSN: 18733360     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2013.03.023     Document Type: Article

References (34)

1. Bach M., Bach D., De Zwaan M., Serim M. Validierung der deutschen Version der 20-Item Toronto-Alexithymie-Skala bei Normalpersonen und psychiatrischen Patienten, Psychother. Psychosom. Med. Psych. 1996, 46:23-28.
2. Bagby R.M., Parker J.D.A., Taylor G.J. The twenty-item Toronto Alexithymia Scale: I. Item selection and cross-validation of the factor structure. J. Psychosom. Res. 1994, 38:23-32.
3. Buchanan T.W., Kern S., Allen J.S., Tranel D., Kirschbaum C. Circadian regulation of cortisol after hippocampal damage in humans. Bio. Psychiatry 2004, 56:651-656.
4. Clow A., Hucklebridge F., Stalder T., Evans P., Thorn L. The cortisol awakening response: more than a measure of HPA axis function. Neurosci. Biobehav. Rev. 2010, 35:97-103.
5. Davis M.H. Measuring individual differences in empathy: evidence for a multidimensional approach. J. Pers. Soc. Psych. 1983, 44:113.
6. De Gucht V., Heiser W. Alexithymia and somatisation: a quantitative review of the literature. J. Psychosom. Res. 2003, 54:425-434.
7. De Timary P., Roy E., Luminet O., Fillée C., Mikolajczak M. Relationship between alexithymia, alexithymia factors and salivary cortisol in men exposed to a social stress test. Psychoneuroendocrinology 2008, 33:1160-1164.
8. Dockray S., Bhattacharyya M.R., Molloy G.J., Steptoe A. The cortisol awakening response in relation to objective and subjective measures of waking in the morning. Psychoneuroendocrinology 2008, 33:77-82.
9. Dressendorfer R.A., Kirschbaum C., Rohde W., Stahl F., Strasburger C.J. Synthesis of a cortisolbiotin conjugate and evaluation as a tracer in an immunoassay for salivary cortisol measurement. J. Steroid. Biochem. Mol. Biol. 1992, 43:683-692.
10. Fekedulegn D.B., Andrew M.E., Burchfiel C.M., Violanti J.M., Hartley T.A., Charles L.E., Miller D.B. Area under the curve and other summary indicators of repeated waking cortisol measurements. Psychosom. Med. 2007, 69:651-659.
11. Franz M., Popp K., Schaefer R., Sitte W., Schneider C., Hardt J., Decker O., Braehler E. Alexithymia in the German general population. Soc. Psych. Psych. Epidemiol. 2008, 43:54-62.
12. Fries E., Hesse J., Hellhammer J., Hellhammer D.H. A new view on hypocortisolism. Psychoneuroendocrinology 2005, 30:1010-1016.
13. Fries E., Dettenborn L., Kirschbaum C. The cortisol awakening response (CAR): facts and future directions. Int. J. Psychophysiol. 2009, 72:67-73.
14. Harris A., Ursin H., Murison R., Eriksen H.R. Coffee, stress and cortisol in nursing staff. Psychoneuroendocrinology 2007, 32:322-330.
15. Huber A., Suman A.L., Biasi G., Carli G. Alexithymia in fibromyalgia syndrome: associations with ongoing pain, experimental pain sensitivity and illness behavior. J. Psychosom. Res. 2009, 66:425-433.
16. Kudielka B.M., Broderick J.E., Kirschbaum C. Compliance with saliva sampling protocols: electronic monitoring reveals invalid cortisol profiles in noncompliant subjects. Psychosom. Med. 2003, 65:313-319.
17. Kudielka B.M., Wüst S. Human models in acute and chronic stress: assessing determinants of individual hypothalamus-pituitary-adrenal axis activity and reactivity. Stress 2010, 13:1-14.
18. Lumley M.A., Stettner L., Wehmer F. How are alexithymia and physical illness linked? A review and critique of pathways. J. Psychosom. Res. 1996, 41:505-518.
19. Martin J.B., Pihl R.O. The stress-alexithymia hypothesis: theoretical and empirical considerations. Psychother. Psychosom. 1985, 43:169-176.
20. Mattila A.K., Salminen J.K., Nummi T., Joukamaa M. Age is strongly associated with alexithymia in the general population. J. Psychosom. Res. 2006, 61:629-635.
21. Moriguchi Y., Decety J., Ohnishi T., Maeda M., Mori T., Nemoto K., Matsuda H., Komaki G. Empathy and judging other's pain: an fMRI study of alexithymia. Cerebral Cortex 2007, 17:2223-2234.
22. Müller J., Bühner M., Ellgring H. The assessment of alexithymia: psychometric properties and validity of the Bermond-Vorst alexithymia questionnaire. Pers. Ind. Dif. 2004, 37:373-391.
23. Papciak A.S., Feuerstein M., Spiegel J.A. Stress reactivity in alexithymia: decoupling of physiological and cognitive responses. J. Hum. Stress 1985, 11:135-142.
24. Sheehan D.V., Lecrubier Y., Sheehan K.H., Amorim P., Janavs J., Weiller E., Hergueta T., Baker R., Dunbar G.C. The Mini-International Neuropsychiatric Interview (M.I.N.I): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J. Clin. Psychiatry 1998, 59:22-33.
25. Sifneos P.E. The prevalence of alexithymic characteristics in psychosomatic patients. Psychother. Psychosom. 1973, 22:270-285.
26. Speranza M., Loas G., Wallier J., Corcos M. Predictive value of alexithymia in patients with eating disorders: a 3-year prospective study. J. Psychosom. Res. 2007, 63:365-371.
27. Stone L.A., Nielson K.A. Intact physiological responses to arousal with impaired emotional recognition in alexithymia. Psychother. Psychosom. 2001, 70:92-102.
28. Taylor G.J., Bagby R.M., Parker J.D. The alexithymia construct: a potential paradigm for psychosomatic medicine. Psychosom.: J. Consult. Lia. Psychiatry 1991, 32:153-164.
29. Thorn L., Hucklebridge F., Evans P., Clow A. Suspected non-adherence and weekend versus week day differences in the awakening cortisol response. Psychoneuroendocrinology 2006, 31:1009-1018.
30. Tsigos C., Chrousos G.P. Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress. J. Psychosom. Res. 2002, 53:865-871.
31. Vorst H.C.M. Validity and reliability of the Bermond-Vorst Alexithymia Questionnaire. Pers. Ind. Dif. 2001, 30:413-434.
32. Wehmer F., Brejnak C., Lumley M., Stettner L. Alexithymia and physiological reactivity to emotion-provoking visual scenes. J. Nerv. Men. Dis. 1995, 183:351-357.
33. Wright C.E., Steptoe A. Subjective socioeconomic position, gender and cortisol responses to waking in an elderly population. Psychoneuroendocrinology 2005, 30:582-590.
34. Wüst S., Federenko I., Hellhammer D.H., Kirschbaum C. Genetic factors, perceived chronic stress, and the free cortisol response to awakening. Psychoneuroendocrinology 2000, 25:707-720.