Antihistaminic drug olopatadine downmodulates T cell chemotaxis toward CXCL10 by reducing CXCR3 expression, F-actin polymerization and calcium influx in patients with alopecia areata

Journal of Dermatological Science

Volumn 72, Issue 1, 2013, Pages 68-71

  Ito, Taisuke ^a   Fujiyama, Toshiharu ^a   Hashizume, Hideo ^b   Tokura, Yoshiki ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SHIMADA MUNICIPAL HOSPITAL   (Japan)

Author keywords

Alopecia areata; Chemotaxis; CXCL10; Olopatadine chroride; Swarm of bees

Indexed keywords

CHEMOKINE RECEPTOR CXCR3; CXCL9 CHEMOKINE; F ACTIN; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; OLOPATADINE;

ACTIN POLYMERIZATION; ALOPECIA AREATA; CALCIUM TRANSPORT; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHEMOTAXIS; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE DURATION; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LETTER; PRIORITY JOURNAL; PROTEIN EXPRESSION; TREATMENT RESPONSE;

ALOPECIA AREATA; CHEMOTAXIS; CXCL10; OLOPATADINE CHRORIDE; SWARM OF BEES;

ACTINS; ALOPECIA AREATA; CALCIUM SIGNALING; CHEMOKINE CXCL10; CHEMOTAXIS, LEUKOCYTE; DIBENZOXEPINS; HISTAMINE H1 ANTAGONISTS, NON-SEDATING; HUMANS; RECEPTORS, CXCR3; T-LYMPHOCYTES;

EID: 84883808707     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2013.04.029     Document Type: Letter

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