Expression of interleukin-33 and ST2 in nonrheumatic aortic valve stenosis

International Journal of Cardiology

Volumn 168, Issue 1, 2013, Pages 529-531

  Sawada, Hisashi ^a   Naito, Yoshiro ^a   Hirotani, Shinichi ^a   Akahori, Hirokuni ^a   Iwasaku, Toshihiro ^a   Okuhara, Yoshitaka ^a   Miki, Kojiro ^a   Eguchi, Akiyo ^a   Mitsuno, Masataka ^a   Miyamoto, Yuji ^a   Ohyanagi, Mitsumasa ^a   Tsujino, Takeshi ^a   Masuyama, Tohru ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

Aortic valve stenosis; Inflammation; Interleukin 33; ST2

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CD68 ANTIGEN; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 33; ST2 PROTEIN; UNCLASSIFIED DRUG;

AGED; AORTA VALVE REPLACEMENT; AORTA VALVE STENOSIS; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INHIBITION KINETICS; LETTER; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; MYOFIBROBLAST; PATHOPHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; UPREGULATION; WESTERN BLOTTING;

AORTIC VALVE STENOSIS; INFLAMMATION; INTERLEUKIN-33; ST2;

AGED; AORTIC VALVE STENOSIS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKINS; MALE; RECEPTORS, CELL SURFACE;

EID: 84883800328     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2012.12.059     Document Type: Article

References (7)

1. R.V. Freeman, and C.M. Otto Spectrum of calcific aortic valve disease: pathogenesis, disease progression, and treatment strategies Circulation 111 2005 3316 3326
2. J. Shmitz, A. Owyang, and E. Oldham IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines Immunity 23 2005 479 490
3. A.M. Miller, D. Xu, and D.L. Asquith IL-33 reduces the development of atherosclerosis J Exp Med 205 2008 339 346
4. Y. Naito, T. Tsujino, and K. Wakabayashi Increased interleukin-18 expression in nonrheumatic aortic valve stenosis Int J Cardiol 144 2010 260 263
5. H. Hayakawa, M. Hayakawa, A. Kume, and S. Tominaga Soluble ST2 blocks interleukin-33 signaling in allergic airway inflammation J Biol Chem 282 2007 26369 26380
6. A.M. Miller, and F.Y. Liew The IL-33/ST2 pathway - A new therapeutic target in cardiovascular disease Pharmacol Ther 131 2011 179 186
7. L. Pastorelli, R.R. Garg, and S.B. Hoang Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis Proc Natl Acad Sci U S A 107 2010 8017 8022