-
1
-
-
0036845563
-
Polymorphisms in the promoter of the human APP gene: Functional evaluation and allele frequencies in Alzheimer disease
-
Athan ES, Lee JH, Arriaga A, Mayeux RP, Tycko B. 2002. Polymorphisms in the promoter of the human APP gene: Functional evaluation and allele frequencies in Alzheimer disease. Arch Neurol 59(11):1793-1799.
-
(2002)
Arch Neurol
, vol.59
, Issue.11
, pp. 1793-1799
-
-
Athan, E.S.1
Lee, J.H.2
Arriaga, A.3
Mayeux, R.P.4
Tycko, B.5
-
2
-
-
0036461061
-
Investigation of the functional effect of monoamine oxidase polymorphisms in human brain
-
Balciuniene J, Emilsson L, Oreland L, Pettersson U, Jazin E. 2002. Investigation of the functional effect of monoamine oxidase polymorphisms in human brain. Hum Genet 110(1):1-7.
-
(2002)
Hum Genet
, vol.110
, Issue.1
, pp. 1-7
-
-
Balciuniene, J.1
Emilsson, L.2
Oreland, L.3
Pettersson, U.4
Jazin, E.5
-
3
-
-
12244296117
-
Results of a high-resolution genome screen of 437 Alzheimer's disease families
-
Blacker D, Bertram L, Saunders AJ, Moscarillo TJ, Albert MS, Wiener H, Perry RT, Collins JS, Harrell LE, Go RC, et al. 2003. Results of a high-resolution genome screen of 437 Alzheimer's disease families. Hum Mol Genet 12(1):23-32.
-
(2003)
Hum Mol Genet
, vol.12
, Issue.1
, pp. 23-32
-
-
Blacker, D.1
Bertram, L.2
Saunders, A.J.3
Moscarillo, T.J.4
Albert, M.S.5
Wiener, H.6
Perry, R.T.7
Collins, J.S.8
Harrell, L.E.9
Go, R.C.10
-
4
-
-
0037534913
-
Accuracy of collateral source reports in very mild to mild dementia of the Alzheimer type
-
Cacchione PZ, Powlishta KK, Grant EA, Buckles VD, Morris JC. 2003. Accuracy of collateral source reports in very mild to mild dementia of the Alzheimer type. J Am Geriatr Soc 51(6):819-823.
-
(2003)
J Am Geriatr Soc
, vol.51
, Issue.6
, pp. 819-823
-
-
Cacchione, P.Z.1
Powlishta, K.K.2
Grant, E.A.3
Buckles, V.D.4
Morris, J.C.5
-
5
-
-
3242708456
-
Regulation of alpha-synuclein expression: Implications for Parkinson's disease
-
Chiba-Falek O, Nussbaum RL. 2003. Regulation of alpha-synuclein expression: Implications for Parkinson's disease. Cold Spring Harb Symp Quant Biol 68:409-415.
-
(2003)
Cold Spring Harb Symp Quant Biol
, vol.68
, pp. 409-415
-
-
Chiba-Falek, O.1
Nussbaum, R.L.2
-
6
-
-
0033771358
-
TCS: A computer program to estimate gene genealogies
-
Clement M, Posada D, Crandall KA. 2000. TCS: A computer program to estimate gene genealogies. Mol Ecol 9:1657-1659.
-
(2000)
Mol Ecol
, vol.9
, pp. 1657-1659
-
-
Clement, M.1
Posada, D.2
Crandall, K.A.3
-
7
-
-
0041857847
-
Pedigree disequilibrium tests for multilocus haplotypes
-
Dudbridge F. 2003. Pedigree disequilibrium tests for multilocus haplotypes. Genet Epidemiol 25(2):115-121.
-
(2003)
Genet Epidemiol
, vol.25
, Issue.2
, pp. 115-121
-
-
Dudbridge, F.1
-
8
-
-
0035880458
-
Alpha-Synuclein gene haplotypes are associated with Parkinson's disease
-
Farrer M, Maraganore DM, Lockhart P, Singleton A, Lesnick TG, de Andrade M, West A, de Silva R, Hardy J, Hernandez D. 2001. Alpha-Synuclein gene haplotypes are associated with Parkinson's disease. Hum Mol Genet 10(17):1847-1851.
-
(2001)
Hum Mol Genet
, vol.10
, Issue.17
, pp. 1847-1851
-
-
Farrer, M.1
Maraganore, D.M.2
Lockhart, P.3
Singleton, A.4
Lesnick, T.G.5
de Andrade, M.6
West, A.7
de Silva, R.8
Hardy, J.9
Hernandez, D.10
-
9
-
-
0026088977
-
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
-
Goate A, Chartier-Harlin MC, Mullan M, Brown J, Crawford F, Fidani L, Giuffra L, Haynes A, Irving N, James L, et al. 1991. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349(6311):704-706.
-
(1991)
Nature
, vol.349
, Issue.6311
, pp. 704-706
-
-
Goate, A.1
Chartier-Harlin, M.C.2
Mullan, M.3
Brown, J.4
Crawford, F.5
Fidani, L.6
Giuffra, L.7
Haynes, A.8
Irving, N.9
James, L.10
-
10
-
-
29244448999
-
-
Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L et al. 2006. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. Am J Hum Genet 78(1):78-88.
-
Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L et al. 2006. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. Am J Hum Genet 78(1):78-88.
-
-
-
-
11
-
-
4344648449
-
Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis
-
Herzig MC, Winkler DT, Burgermeister P, Pfeifer M, Kohler E, Schmidt SD, Danner S, Abramowski D, Sturchler-Pierrat C, Burki K et al. 2004. Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis. Nat Neurosci 7(9):954-960.
-
(2004)
Nat Neurosci
, vol.7
, Issue.9
, pp. 954-960
-
-
Herzig, M.C.1
Winkler, D.T.2
Burgermeister, P.3
Pfeifer, M.4
Kohler, E.5
Schmidt, S.D.6
Danner, S.7
Abramowski, D.8
Sturchler-Pierrat, C.9
Burki, K.10
-
12
-
-
0026463326
-
Down syndrome and Alzheimer disease
-
Hyman BT. 1992. Down syndrome and Alzheimer disease. Prog Clin Biol Res 379:123-142.
-
(1992)
Prog Clin Biol Res
, vol.379
, pp. 123-142
-
-
Hyman, B.T.1
-
13
-
-
0029002233
-
-
Kida E, Choi-Miura NH, Wisniewski KE. 1995. Deposition of apolipoproteins E and J in senile plaques is topographically determined in both Alzheimer's disease and Down's syndrome brain. Brain Res 685(1-2):211-216.
-
Kida E, Choi-Miura NH, Wisniewski KE. 1995. Deposition of apolipoproteins E and J in senile plaques is topographically determined in both Alzheimer's disease and Down's syndrome brain. Brain Res 685(1-2):211-216.
-
-
-
-
14
-
-
70350189803
-
Common haplotypes in five genes influence genetic variance of LDL and HDL cholesterol in the general population
-
Knoblauch H, Bauerfeind A, Krahenbuhl C, Daury A, Rohde K, Bejanin S, Essioux L, Schuster H, Luft FC, Reich JG. 2002. Common haplotypes in five genes influence genetic variance of LDL and HDL cholesterol in the general population. Hum Mol Genet 11(12):1477-1485.
-
(2002)
Hum Mol Genet
, vol.11
, Issue.12
, pp. 1477-1485
-
-
Knoblauch, H.1
Bauerfeind, A.2
Krahenbuhl, C.3
Daury, A.4
Rohde, K.5
Bejanin, S.6
Essioux, L.7
Schuster, H.8
Luft, F.C.9
Reich, J.G.10
-
15
-
-
26944436685
-
-
Lahiri DK, Ge YW, Maloney B, Wavrant-De Vrieze F, Hardy J. 2005. Characterization of two APP gene promoter polymorphisms that appear to influence risk of late-onset Alzheimer's disease. Neurobiol Aging 26(10):1329-1341.
-
Lahiri DK, Ge YW, Maloney B, Wavrant-De Vrieze F, Hardy J. 2005. Characterization of two APP gene promoter polymorphisms that appear to influence risk of late-onset Alzheimer's disease. Neurobiol Aging 26(10):1329-1341.
-
-
-
-
16
-
-
0031685162
-
Polymorphic tetranucleotide repeat site within intron 7 of the beta-amyloid precursor protein gene and its lack of association with Alzheimer's disease
-
Li L, Perry R, Wu J, Pham D, Ohman T, Harrell LE, Go RC, Fukuchi K. 1998. Polymorphic tetranucleotide repeat site within intron 7 of the beta-amyloid precursor protein gene and its lack of association with Alzheimer's disease. Hum Genet 103(1):86-89.
-
(1998)
Hum Genet
, vol.103
, Issue.1
, pp. 86-89
-
-
Li, L.1
Perry, R.2
Wu, J.3
Pham, D.4
Ohman, T.5
Harrell, L.E.6
Go, R.C.7
Fukuchi, K.8
-
17
-
-
8144228132
-
-
Li Y, Nowotny P, Holmans P, Smemo S, Kauwe JS, Hinrichs AL, Tacey K, Doil L, van Luchene R, Garcia V et al. 2004. Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family. Proc Natl Acad Sci USA 101(44):15688-15693.
-
Li Y, Nowotny P, Holmans P, Smemo S, Kauwe JS, Hinrichs AL, Tacey K, Doil L, van Luchene R, Garcia V et al. 2004. Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family. Proc Natl Acad Sci USA 101(44):15688-15693.
-
-
-
-
18
-
-
0030859067
-
Clinical dementia rating training and reliability in multicenter studies: The Alzheimer's Disease Cooperative Study experience
-
Morris JC, Ernesto C, Schafer K, Coats M, Leon S, Sano M, Thai LJ, Woodbury P. 1997. Clinical dementia rating training and reliability in multicenter studies: The Alzheimer's Disease Cooperative Study experience. Neurology 48(6):1508-1510.
-
(1997)
Neurology
, vol.48
, Issue.6
, pp. 1508-1510
-
-
Morris, J.C.1
Ernesto, C.2
Schafer, K.3
Coats, M.4
Leon, S.5
Sano, M.6
Thai, L.J.7
Woodbury, P.8
-
19
-
-
18244407351
-
Full genome screen for Alzheimer disease: Stage II analysis
-
Myers A, Wavrant De-Vrieze F, Holmans P, Hamshere M, Crook R, Compton D, Marshall H, Meyer D, Shears S, Booth J et al. 2002. Full genome screen for Alzheimer disease: Stage II analysis. Am J Med Genet 114(2):235-244.
-
(2002)
Am J Med Genet
, vol.114
, Issue.2
, pp. 235-244
-
-
Myers, A.1
Wavrant De-Vrieze, F.2
Holmans, P.3
Hamshere, M.4
Crook, R.5
Compton, D.6
Marshall, H.7
Meyer, D.8
Shears, S.9
Booth, J.10
-
20
-
-
21444449693
-
-
Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell T, Holmans P, Hamshere M, Turic D, Jehu L, Hollingworth P et al. 2005. Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme. Am J Med Genet B Neuropsychiatr Genet 136(1):62-68.
-
Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell T, Holmans P, Hamshere M, Turic D, Jehu L, Hollingworth P et al. 2005. Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme. Am J Med Genet B Neuropsychiatr Genet 136(1):62-68.
-
-
-
-
21
-
-
0036301635
-
-
Olson JM, Goddard KA, Dudek DM. 2002. A second locus for very-late-onset Alzheimer disease: A genome scan reveals linkage to 20p and epistasis between 20p and the amyloid precursor protein region. Am J Hum Genet 71(1):154-161.
-
Olson JM, Goddard KA, Dudek DM. 2002. A second locus for very-late-onset Alzheimer disease: A genome scan reveals linkage to 20p and epistasis between 20p and the amyloid precursor protein region. Am J Hum Genet 71(1):154-161.
-
-
-
-
22
-
-
3142552775
-
Molecular genetics of Alzheimer's disease
-
Pastor P, Goate AM. 2004. Molecular genetics of Alzheimer's disease. Curr Psychiatry Rep 6(2):125-133.
-
(2004)
Curr Psychiatry Rep
, vol.6
, Issue.2
, pp. 125-133
-
-
Pastor, P.1
Goate, A.M.2
-
23
-
-
0031939059
-
Molecular mapping of Alzheimer-type dementia in Down's syndrome
-
Prasher VP, Farrer MJ, Kessling AM, Fisher EM, West RJ, Barber PC, Butler AC. 1998. Molecular mapping of Alzheimer-type dementia in Down's syndrome. Ann Neurol 43(3):380-383.
-
(1998)
Ann Neurol
, vol.43
, Issue.3
, pp. 380-383
-
-
Prasher, V.P.1
Farrer, M.J.2
Kessling, A.M.3
Fisher, E.M.4
West, R.J.5
Barber, P.C.6
Butler, A.C.7
-
25
-
-
29444442794
-
-
Rovelet-Lecrax A, Hannequin D, Raux G, Le Meur N, Laquerriere A, Vital A, Dumanchin C, Feuillette S, Brice A, Vercelletto M et al. 2006. APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy. Nat Genet 38(1):24-26.
-
Rovelet-Lecrax A, Hannequin D, Raux G, Le Meur N, Laquerriere A, Vital A, Dumanchin C, Feuillette S, Brice A, Vercelletto M et al. 2006. APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy. Nat Genet 38(1):24-26.
-
-
-
-
26
-
-
0024342769
-
Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease
-
Rumble B, Retallack R, Hilbich C, Simms G, Multhaup G, Martins R, Hockey A, Montgomery P, Beyreuther K, Masters CL. 1989. Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease. N Engl J Med 320(22):1446-1452.
-
(1989)
N Engl J Med
, vol.320
, Issue.22
, pp. 1446-1452
-
-
Rumble, B.1
Retallack, R.2
Hilbich, C.3
Simms, G.4
Multhaup, G.5
Martins, R.6
Hockey, A.7
Montgomery, P.8
Beyreuther, K.9
Masters, C.L.10
-
27
-
-
0035815573
-
Elevated plasma amyloid beta-peptide 1-42 and onset of dementia in adults with Down syndrome
-
Schupf N, Patel B, Silverman W, Zigman WB, Zhong N, Tycko B, Mehta PD, Mayeux R. 2001. Elevated plasma amyloid beta-peptide 1-42 and onset of dementia in adults with Down syndrome. Neurosci Lett 301(3):199-203.
-
(2001)
Neurosci Lett
, vol.301
, Issue.3
, pp. 199-203
-
-
Schupf, N.1
Patel, B.2
Silverman, W.3
Zigman, W.B.4
Zhong, N.5
Tycko, B.6
Mehta, P.D.7
Mayeux, R.8
-
28
-
-
1842507639
-
The law of mass action applied to neurodegenerative disease: A hypothesis concerning the etiology and pathogenesis of complex diseases
-
Singleton A, Myers A, Hardy J. 2004. The law of mass action applied to neurodegenerative disease: A hypothesis concerning the etiology and pathogenesis of complex diseases. Hum Mol Genet 13(Spec No 1):R123-R126.
-
(2004)
Hum Mol Genet
, vol.13
, Issue.SPEC 1
-
-
Singleton, A.1
Myers, A.2
Hardy, J.3
-
29
-
-
0242691208
-
A comparison of bayesian methods for haplotype reconstruction from population genotype data
-
Stephens M, Donnelly P. 2003. A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet 73:1162-1169.
-
(2003)
Am J Hum Genet
, vol.73
, pp. 1162-1169
-
-
Stephens, M.1
Donnelly, P.2
-
30
-
-
0035071957
-
A new statistical method for haplotype reconstruction from population data
-
Stephens M, Smith NJ, Donnelly P. 2001. A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 68:978-989.
-
(2001)
Am J Hum Genet
, vol.68
, pp. 978-989
-
-
Stephens, M.1
Smith, N.J.2
Donnelly, P.3
-
31
-
-
0033766857
-
Cladistic structure within the human Lipoprotein lipase gene and its implications for phenotypic association studies
-
Templeton AR, Weiss KM, Nickerson DA, Boerwinkle E, Sing CF. 2000. Cladistic structure within the human Lipoprotein lipase gene and its implications for phenotypic association studies. Genetics 156(3):1259-1275.
-
(2000)
Genetics
, vol.156
, Issue.3
, pp. 1259-1275
-
-
Templeton, A.R.1
Weiss, K.M.2
Nickerson, D.A.3
Boerwinkle, E.4
Sing, C.F.5
-
32
-
-
13744260018
-
Tree scanning: A method for using haplotype trees in phenotype/ genotype association studies
-
Templeton AR, Maxwell T, Posada D, Stengard JH, Boerwinkle E, Sing CF. 2005. Tree scanning: A method for using haplotype trees in phenotype/ genotype association studies. Genetics 169:441-453.
-
(2005)
Genetics
, vol.169
, pp. 441-453
-
-
Templeton, A.R.1
Maxwell, T.2
Posada, D.3
Stengard, J.H.4
Boerwinkle, E.5
Sing, C.F.6
-
33
-
-
33646886350
-
Promoter mutations that increase amyloid precursor-protein expression are associated with Alzheimer disease
-
Theuns J, Brouwers N, Engelborghs S, Sleegers K, Bogaerts V, Corsmit E, De Pooter T, van Duijn CM, De Deyn PP, Van Broeckhoven C. 2006. Promoter mutations that increase amyloid precursor-protein expression are associated with Alzheimer disease. Am J Hum Genet 78(6):936-946.
-
(2006)
Am J Hum Genet
, vol.78
, Issue.6
, pp. 936-946
-
-
Theuns, J.1
Brouwers, N.2
Engelborghs, S.3
Sleegers, K.4
Bogaerts, V.5
Corsmit, E.6
De Pooter, T.7
van Duijn, C.M.8
De Deyn, P.P.9
Van Broeckhoven, C.10
-
34
-
-
0037173639
-
Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness
-
Van Eerdewegh P, Little RD, Dupuis J, Del Mastro RG, Falls K, Simon J, Torrey D, Pandit S, McKenny J, Braunschweiger K et al. 2002. Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. Nature 418(6896):426-430.
-
(2002)
Nature
, vol.418
, Issue.6896
, pp. 426-430
-
-
Van Eerdewegh, P.1
Little, R.D.2
Dupuis, J.3
Del Mastro, R.G.4
Falls, K.5
Simon, J.6
Torrey, D.7
Pandit, S.8
McKenny, J.9
Braunschweiger, K.10
-
35
-
-
0033538502
-
-
Wavrant-De Vrieze F, Crook R, Holmans P, Kehoe P, Owen MJ, Williams J, Roehl K, Laliiri DK, Shears S, Booth J et al. 1999. Genetic variability at the amyloid-beta precursor protein locus may contribute to the risk of late-onset Alzheimer's disease. Neurosci Lett 269(2):67-70.
-
Wavrant-De Vrieze F, Crook R, Holmans P, Kehoe P, Owen MJ, Williams J, Roehl K, Laliiri DK, Shears S, Booth J et al. 1999. Genetic variability at the amyloid-beta precursor protein locus may contribute to the risk of late-onset Alzheimer's disease. Neurosci Lett 269(2):67-70.
-
-
-
-
36
-
-
0021956826
-
Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome
-
Wisniewski KE, Wisniewski HM, Wen GY. 1985. Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome. Ann Neurol 17(3):278-282.
-
(1985)
Ann Neurol
, vol.17
, Issue.3
, pp. 278-282
-
-
Wisniewski, K.E.1
Wisniewski, H.M.2
Wen, G.Y.3
-
37
-
-
0030022841
-
Prevalence of dementia in adults with and without Down syndrome
-
Zigman WB, Schupf N, Sersen E, Silverman W. 1996. Prevalence of dementia in adults with and without Down syndrome. Am J Ment Retard 100(4):403-412.
-
(1996)
Am J Ment Retard
, vol.100
, Issue.4
, pp. 403-412
-
-
Zigman, W.B.1
Schupf, N.2
Sersen, E.3
Silverman, W.4
|