Retigeric acid B-induced mitophagy by oxidative stress attenuates cell death against prostate cancer cells in vitro

Acta Pharmacologica Sinica

Volumn 34, Issue 9, 2013, Pages 1183-1191

  Liu, Yong Qing ^a   Ji, Yuan ^a   Li, Xian Zhe ^a   Tian, Ke Li ^a   Young, Charles Y F ^b   Lou, Hong Xiang ^a   Yuan, Hui Qing ^a  

^a SHANDONG UNIVERSITY   (China)

^b DEPARTMENT OF UROLOGY   (United States)

Author keywords

Apoptosis; Mitochondria; Mitophagy; Prostate cancer; Reactive oxygen species (ROS); Retigeric acid B

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; DJ 1 PROTEIN; PENTACYCLIC TRITERPENE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; RETIGERIC ACID B; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOLYSOSOME; CANCER CELL; CANCER CELL CULTURE; CELL DEATH; CELL POPULATION; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DEPOLARIZATION; ELECTRON MICROSCOPY; ENZYME ACTIVATION; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GLIOMA; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOFLUORESCENCE; IN VITRO STUDY; LASER MICROSCOPY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; MITOPHAGY; OXIDATIVE STRESS; PROSTATE CANCER; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING;

CELL DEATH; CELL LINE, TUMOR; HUMANS; MALE; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; OXIDATIVE STRESS; PROSTATIC NEOPLASMS; TRITERPENES;

EID: 84883674690     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2013.68     Document Type: Article

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