Brugia pahangi: Immunization with early L3 ES alters parasite migration, and reduces microfilaremia and lymphatic lesion formation in gerbils (Meriones unguiculatus)

Experimental Parasitology

Volumn 135, Issue 2, 2013, Pages 446-455

  Zipperer, Ginger R ^a,c   Arumugam, Sridhar ^a   Chirgwin, Sharon R ^a   Coleman, Sharon U ^a   Shakya, Krishna P ^b   Klei, Thomas R ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF GUELPH   (Canada)

^c PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

Author keywords

Brugia pahangi; Excretory secretory products (ES); Fecundity; Filariasis; Immunization; Parasite granulomas; Parasite migration

Indexed keywords

IMMUNOLOGICAL ADJUVANT; L3 ES PROTEIN; PARASITE ANTIBODY; PARASITE ANTIGEN; UNCLASSIFIED DRUG;

ADULT ANIMAL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; BRUGIA PAHANGI; BRUGIAN FILARIASIS; CONTROLLED STUDY; EMBRYO; FEMALE; GERBIL; GRANULOMA; HOST; HUMORAL IMMUNITY; IMMUNITY; IMMUNIZATION; IN VITRO STUDY; LARVA; LYMPHATIC SYSTEM DISEASE; MALE; MERIONES UNGUICULATUS; MICROFILARIASIS; NONHUMAN; PARASITE DEVELOPMENT; PARASITE MIGRATION; PARASITE SURVIVAL; PRIORITY JOURNAL;

1% FISH GELATIN-PBST; AB BUFFER; ABUNDANT LARVAL TRANSCRIPT PROTEIN; ACUTE; ADJUVANT; ADJUVANT IMMUNIZED ANIMALS CHALLENGED WITH L3S INTRADERMALLY; ADJUVANT IMMUNIZED ANIMALS CHALLENGED WITH L3S INTRAPERITONEALLY; AJ; AJ+BP+ID; AJ+BP+IP; ALKALINE PHOSPHATASE; ALT; ANTI-ES FROM EXPERIMENT 1; ANTI-ES FROM EXPERIMENT 2; ANTI-ES1; ANTI-ES2; AP; B. PAHANGI INFECTION OF >1YEAR; B. PAHANGI INFECTION OF 35 DAYS DURATION; B. PAHANGI SOMATIC L3 ANTIGEN; BP; BRUGIA PAHANGI; CHRONIC; ES; ES IMMUNIZED ANIMALS CHALLENGED WITH L3S INTRADERMALLY; ES IMMUNIZED ANIMALS CHALLENGED WITH L3S INTRAPERITONEALLY; ES+BP+ID; ES+BP+IP; EXCRETORY/SECRETORY PRODUCTS; EXCRETORY/SECRETORY PRODUCTS (ES); FECUNDITY; FILARIASIS; GOAT ANTI-MOUSE IGG ANTIBODY CONJUGATED TO ALKALINE PHOSPHATASE; ID; IGG-AP; ILEO-LUMBAR VESSELS; ILT; ILV; IMMUNIZATION; INFECTIVE THIRD STAGE LARVAE; INTRADERMAL; INTRALYMPHATIC THROMBI; INTRAPERITONEAL; IP; L3; PARASITE GRANULOMAS; PARASITE MIGRATION; PBS-0.05% TWEEN 20; PBST; RIGHT AND LEFT POPLITEAL LYMPH NODES; RIGHT AND LEFT RENAL LYMPH NODES; RIGHT AND LEFT SPERMATIC CORD LYMPHATICS; RIGHT AND LEFT SUB-INGUINAL AND ILIAC NODES; RIGHT AND LEFT TESTES; RPOP AND LPOP; RRLN AND LRLN; RSPCD AND LSPCD; RSUB AND LSUB; RTEST AND LTEST; SL3A;

ANIMALS; ANTIBODIES, HELMINTH; ANTIGENS, HELMINTH; BLOTTING, WESTERN; BRUGIA PAHANGI; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; FILARIASIS; GERBILLINAE; HEART; HELMINTH PROTEINS; IMMUNIZATION; IMMUNOGLOBULIN G; LARVA; LUNG; LYMPH NODES; LYMPHATIC SYSTEM; MALE;

EID: 84883673961     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2013.08.007     Document Type: Article

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