메뉴 건너뛰기




Volumn 62, Issue 7, 2013, Pages 2492-2499

Functional redundancy of CXCR3/CXCL10 signaling in the recruitment of diabetogenic cytotoxic T lymphocytes to pancreatic islets in a virally induced autoimmune diabetes model

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR3; GAMMA INTERFERON INDUCIBLE PROTEIN 10; CXCL10 PROTEIN, MOUSE; CXCR3 PROTEIN, MOUSE; NEUTRALIZING ANTIBODY;

EID: 84883667327     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-1370     Document Type: Article
Times cited : (25)

References (25)
  • 1
    • 0036913215 scopus 로고    scopus 로고
    • Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis
    • Frigerio S, Junt T, Lu B, et al. Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis. Nat Med 2002;8:1414-1420
    • (2002) Nat Med , vol.8 , pp. 1414-1420
    • Frigerio, S.1    Junt, T.2    Lu, B.3
  • 2
    • 0346366978 scopus 로고    scopus 로고
    • Among CXCR3 chemokines, IFN-gamma-inducible protein of 10 kDa (CXC chemokine ligand (CXCL) 10) but not monokine induced by IFN-gamma (CXCL9) imprints a pattern for the subsequent development of autoimmune disease
    • Christen U, McGavern DB, Luster AD, von Herrath MG, Oldstone MB. Among CXCR3 chemokines, IFN-gamma-inducible protein of 10 kDa (CXC chemokine ligand (CXCL) 10) but not monokine induced by IFN-gamma (CXCL9) imprints a pattern for the subsequent development of autoimmune disease. J Immunol 2003;171:6838-6845
    • (2003) J Immunol , vol.171 , pp. 6838-6845
    • Christen, U.1    McGavern, D.B.2    Luster, A.D.3    Von Herrath, M.G.4    Oldstone, M.B.5
  • 3
    • 9144243642 scopus 로고    scopus 로고
    • CXC chemokine ligand 10 neutralization suppresses the occurrence of diabetes in nonobese diabetic mice through enhanced beta cell proliferation without affecting insulitis
    • Morimoto J, Yoneyama H, Shimada A, et al. CXC chemokine ligand 10 neutralization suppresses the occurrence of diabetes in nonobese diabetic mice through enhanced beta cell proliferation without affecting insulitis. J Immunol 2004;173:7017-7024
    • (2004) J Immunol , vol.173 , pp. 7017-7024
    • Morimoto, J.1    Yoneyama, H.2    Shimada, A.3
  • 4
    • 58749093419 scopus 로고    scopus 로고
    • CXCL10 impairs beta cell function and viability in diabetes through TLR4 signaling
    • Schulthess FT, Paroni F, Sauter NS, et al. CXCL10 impairs beta cell function and viability in diabetes through TLR4 signaling. Cell Metab 2009; 9:125-139
    • (2009) Cell Metab , vol.9 , pp. 125-139
    • Schulthess, F.T.1    Paroni, F.2    Sauter, N.S.3
  • 5
    • 84866359284 scopus 로고    scopus 로고
    • Acceleration of diabetes development in CXC chemokine receptor 3 (CXCR3)-deficient NOD mice
    • Yamada Y, Okubo Y, Shimada A, et al. Acceleration of diabetes development in CXC chemokine receptor 3 (CXCR3)-deficient NOD mice. Diabetologia 2012;55:2238-2245
    • (2012) Diabetologia , vol.55 , pp. 2238-2245
    • Yamada, Y.1    Okubo, Y.2    Shimada, A.3
  • 6
    • 79960985829 scopus 로고    scopus 로고
    • Small molecule CXCR3 antagonist NIBR2130 has only a limited impact on type 1 diabetes in a virus-induced mouse model
    • Christen S, Holdener M, Beerli C, et al. Small molecule CXCR3 antagonist NIBR2130 has only a limited impact on type 1 diabetes in a virus-induced mouse model. Clin Exp Immunol 2011;165:318-328
    • (2011) Clin Exp Immunol , vol.165 , pp. 318-328
    • Christen, S.1    Holdener, M.2    Beerli, C.3
  • 7
    • 70349651422 scopus 로고    scopus 로고
    • Enterovirus infection, CXC chemokine ligand 10 (CXCL10), and CXCR3 circuit: A mechanism of accelerated betacell failure in fulminant type 1 diabetes
    • Tanaka S, Nishida Y, Aida K, et al. Enterovirus infection, CXC chemokine ligand 10 (CXCL10), and CXCR3 circuit: a mechanism of accelerated betacell failure in fulminant type 1 diabetes. Diabetes 2009;58:2285-2291
    • (2009) Diabetes , vol.58 , pp. 2285-2291
    • Tanaka, S.1    Nishida, Y.2    Aida, K.3
  • 8
    • 74549199886 scopus 로고    scopus 로고
    • Islet inflammation and CXCL10 in recent-onset type 1 diabetes
    • Roep BO, Kleijwegt FS, van Halteren AG, et al. Islet inflammation and CXCL10 in recent-onset type 1 diabetes. Clin Exp Immunol 2010;159:338- 343
    • (2010) Clin Exp Immunol , vol.159 , pp. 338-343
    • Roep, B.O.1    Kleijwegt, F.S.2    Van Halteren, A.G.3
  • 9
    • 78649764557 scopus 로고    scopus 로고
    • Expression of chemokines, CXC chemokine ligand 10 (CXCL10) and CXCR3 in the inflamed islets of patients with recent-onset autoimmune type 1 diabetes
    • Uno S, Imagawa A, Saisho K, et al. Expression of chemokines, CXC chemokine ligand 10 (CXCL10) and CXCR3 in the inflamed islets of patients with recent-onset autoimmune type 1 diabetes. Endocr J 2010;57: 991-996
    • (2010) Endocr J , vol.57 , pp. 991-996
    • Uno, S.1    Imagawa, A.2    Saisho, K.3
  • 10
    • 84863053082 scopus 로고    scopus 로고
    • Expression and regulation of chemokines in murine and human type 1 diabetes
    • Sarkar SA, Lee CE, Victorino F, et al. Expression and regulation of chemokines in murine and human type 1 diabetes. Diabetes 2012;61:436- 446
    • (2012) Diabetes , vol.61 , pp. 436-446
    • Sarkar, S.A.1    Lee, C.E.2    Victorino, F.3
  • 11
    • 0036533663 scopus 로고    scopus 로고
    • IFNgamma-Inducible protein 10 (IP-10; CXCL10)-Deficient mice reveal a role for IP-10 in effector T cell generation and trafficking
    • Dufour JH, Dziejman M, Liu MT, Leung JH, Lane TE, Luster AD. IFNgamma- inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking. J Immunol 2002;168: 3195-3204
    • (2002) J Immunol , vol.168 , pp. 3195-3204
    • Dufour, J.H.1    Dziejman, M.2    Liu, M.T.3    Leung, J.H.4    Lane, T.E.5    Luster, A.D.6
  • 12
    • 0024307348 scopus 로고
    • Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
    • Pircher H, Bürki K, Lang R, Hengartner H, Zinkernagel RM. Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature 1989;342:559-561
    • (1989) Nature , vol.342 , pp. 559-561
    • Pircher, H.1    Bürki, K.2    Lang, R.3    Hengartner, H.4    Zinkernagel, R.M.5
  • 14
    • 0025755292 scopus 로고
    • Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice
    • Ohashi PS, Oehen S, Buerki K, et al. Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice. Cell 1991;65: 305-317
    • (1991) Cell , vol.65 , pp. 305-317
    • Ohashi, P.S.1    Oehen, S.2    Buerki, K.3
  • 15
    • 0025754853 scopus 로고
    • Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: Role of anti-self (virus) immune response
    • Oldstone MB, Nerenberg M, Southern P, Price J, Lewicki H. Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune response. Cell 1991;65:319-331
    • (1991) Cell , vol.65 , pp. 319-331
    • Oldstone, M.B.1    Nerenberg, M.2    Southern, P.3    Price, J.4    Lewicki, H.5
  • 16
    • 0037235364 scopus 로고    scopus 로고
    • Transgenic mice with green fluorescent protein-labeled pancreatic beta-cells
    • Hara M, Wang X, Kawamura T, et al. Transgenic mice with green fluorescent protein-labeled pancreatic beta-cells. Am J Physiol Endocrinol Metab 2003;284:E177-E183
    • (2003) Am J Physiol Endocrinol Metab , vol.284
    • Hara, M.1    Wang, X.2    Kawamura, T.3
  • 17
    • 77958152283 scopus 로고    scopus 로고
    • Expression level of a pancreatic neo-antigen in beta cells determines degree of diabetes pathogenesis
    • Martinic MM, Huber C, Coppieters K, Oldham JE, Gavin AL, von Herrath MG. Expression level of a pancreatic neo-antigen in beta cells determines degree of diabetes pathogenesis. J Autoimmun 2010;35:404-413
    • (2010) J Autoimmun , vol.35 , pp. 404-413
    • Martinic, M.M.1    Huber, C.2    Coppieters, K.3    Oldham, J.E.4    Gavin, A.L.5    Von Herrath, M.G.6
  • 18
    • 78650819061 scopus 로고    scopus 로고
    • A novel technique for the in vivo imaging of autoimmune diabetes development in the pancreas by two-photon microscopy
    • Coppieters K, Martinic MM, Kiosses WB, Amirian N, von Herrath M. A novel technique for the in vivo imaging of autoimmune diabetes development in the pancreas by two-photon microscopy. PLoS ONE 2010;5: e15732
    • (2010) PLoS ONE , vol.5
    • Coppieters, K.1    Martinic, M.M.2    Kiosses, W.B.3    Amirian, N.4    Von Herrath, M.5
  • 19
    • 0033710213 scopus 로고    scopus 로고
    • IP-10 is critical for effector T cell trafficking and host survival in Toxoplasma gondii infection
    • Khan IA, MacLean JA, Lee FS, et al. IP-10 is critical for effector T cell trafficking and host survival in Toxoplasma gondii infection. Immunity 2000;12:483-494
    • (2000) Immunity , vol.12 , pp. 483-494
    • Khan, I.A.1    Maclean, J.A.2    Lee, F.S.3
  • 20
    • 85047689596 scopus 로고    scopus 로고
    • Cure of prediabetic mice by viral infections involves lymphocyte recruitment along an IP-10 gradient
    • Christen U, Benke D, Wolfe T, et al. Cure of prediabetic mice by viral infections involves lymphocyte recruitment along an IP-10 gradient. J Clin Invest 2004;113:74-84
    • (2004) J Clin Invest , vol.113 , pp. 74-84
    • Christen, U.1    Benke, D.2    Wolfe, T.3
  • 21
    • 1642306410 scopus 로고    scopus 로고
    • Leukocyte attraction through the CCR5 receptor controls progress from insulitis to diabetes in nonobese diabetic mice
    • Carvalho-Pinto C, García MI, Gómez L, et al. Leukocyte attraction through the CCR5 receptor controls progress from insulitis to diabetes in nonobese diabetic mice. Eur J Immunol 2004;34:548-557
    • (2004) Eur J Immunol , vol.34 , pp. 548-557
    • Carvalho-Pinto, C.1    García, M.I.2    Gómez, L.3
  • 22
    • 0037478632 scopus 로고    scopus 로고
    • Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes
    • Lieberman SM, Evans AM, Han B, et al. Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes. Proc Natl Acad Sci USA 2003;100:8384-8388
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8384-8388
    • Lieberman, S.M.1    Evans, A.M.2    Han, B.3
  • 23
    • 84855456086 scopus 로고    scopus 로고
    • Intravital imaging of CTLs killing islet cells in diabetic mice
    • Coppieters K, Amirian N, von Herrath M. Intravital imaging of CTLs killing islet cells in diabetic mice. J Clin Invest 2012;122:119-131
    • (2012) J Clin Invest , vol.122 , pp. 119-131
    • Coppieters, K.1    Amirian, N.2    Von Herrath, M.3
  • 24
    • 35548996783 scopus 로고    scopus 로고
    • Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7
    • Sierro F, Biben C, Martínez-Muñoz L, et al. Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7. Proc Natl Acad Sci USA 2007;104:14759-14764
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 14759-14764
    • Sierro, F.1    Biben, C.2    Martínez-Muñoz, L.3
  • 25
    • 24744439699 scopus 로고    scopus 로고
    • Islet-specific expression of CXCL10 causes spontaneous islet infiltration and accelerates diabetes development
    • Rhode A, Pauza ME, Barral AM, et al. Islet-specific expression of CXCL10 causes spontaneous islet infiltration and accelerates diabetes development. J Immunol 2005;175:3516-3524
    • (2005) J Immunol , vol.175 , pp. 3516-3524
    • Rhode, A.1    Pauza, M.E.2    Barral, A.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.