Niacin suppresses the mitogen-activated protein kinase pathway and attenuates brain injury after cardiac arrest in rats

Critical Care Medicine

Volumn 41, Issue 9, 2013, Pages

  Kwon, Woon Yong ^a   Suh, Gil Joon ^a   Kim, Kyung Su ^a   Lee, Hui Jai ^a   Jeong, Ki Young ^b   Kwak, Young Ho ^a   Kim, Kyuseok ^c  

^a Seoul National University College of Medicine   (South Korea)

^b National Medical Center   (South Korea)

^c Seoul National University Bundang Hospital   (South Korea)

Author keywords

apoptosis; brain; cardiopulmonary resuscitation; heart arrest; mitogen activated protein kinase; niacin

Indexed keywords

CASPASE 3; GLUTATHIONE; HEMOGLOBIN; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTERIAL PRESSURE; ARTICLE; AXONAL INJURY; BLOOD GAS ANALYSIS; BODY WEIGHT; BRAIN INJURY; BRAIN TISSUE; CONTROLLED STUDY; CORONARY HEMODYNAMICS; CORPUS CALLOSUM; DEFIBRILLATION; DRUG MEGADOSE; HEART ARREST; HEART RATE; HEART VENTRICLE FIBRILLATION; IMMUNOHISTOCHEMISTRY; MALE; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN PHOSPHORYLATION; RAT; RESUSCITATION; RETURN OF SPONTANEOUS CIRCULATION; SINGLE DRUG DOSE; WESTERN BLOTTING;

ANIMALS; BRAIN INJURIES; HEART ARREST; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MAP KINASE SIGNALING SYSTEM; NIACIN; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROSPECTIVE STUDIES; RATS; RATS, SPRAGUE-DAWLEY; TREATMENT OUTCOME; VASODILATOR AGENTS;

EID: 84883656516     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31828a2394     Document Type: Article

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