메뉴 건너뛰기




Volumn 41, Issue 9, 2013, Pages 2209-2220

Blood purification and mortality in sepsis: A meta-analysis of randomized trials

Author keywords

blood purification; cytokines; inflammation; metaanalysis; mortality; sepsis

Indexed keywords

ANTIBIOTIC AGENT; FRESH FROZEN PLASMA; NORADRENALIN; POLYMYXIN B;

EID: 84883654315     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31828cf412     Document Type: Review
Times cited : (162)

References (50)
  • 1
    • 0034958947 scopus 로고    scopus 로고
    • Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
    • Angus DC, Linde-Zwirble WT, Lidicker J, et al: Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001; 29:1303-1310
    • (2001) Crit Care Med , vol.29 , pp. 1303-1310
    • Angus, D.C.1    Linde-Zwirble, W.T.2    Lidicker, J.3
  • 2
    • 0037451929 scopus 로고    scopus 로고
    • The epidemiology of sepsis in the United States from 1979 through 2000
    • Martin GS, Mannino DM, Eaton S, et al: The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 2003; 48:1546-1554
    • (2003) N Engl J Med , vol.48 , pp. 1546-1554
    • Martin, G.S.1    Mannino, D.M.2    Eaton, S.3
  • 3
    • 84883653003 scopus 로고    scopus 로고
    • Xigris [drotrecogin alfa (activated)] Accessed January 15 2013
    • Xigris [drotrecogin alfa (activated)]: Market Withdrawal-Failure to Show Survival Benefit. http://www.fda.gov/Safety/MedWatch/SafetyInformation/ SafetyAlertsforHumanMedicalProducts/ucm277143.htm. Accessed January 15, 2013.
    • Market Withdrawal-Failure to Show Survival Benefit
  • 4
    • 38349058657 scopus 로고    scopus 로고
    • Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008
    • Dellinger RP, Levy MM, Carlet JM, et al: Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med 2008; 34:17-60
    • (2008) Intensive Care Med , vol.34 , pp. 17-60
    • Dellinger, R.P.1    Levy, M.M.2    Carlet, J.M.3
  • 5
    • 65249162841 scopus 로고    scopus 로고
    • Continuous renal replacement therapy in sepsis and multisystem organ failure
    • Joannidis M: Continuous renal replacement therapy in sepsis and multisystem organ failure. Semin Dial 2009; 22:160-164
    • (2009) Semin Dial , vol.22 , pp. 160-164
    • Joannidis, M.1
  • 6
    • 33748849427 scopus 로고    scopus 로고
    • Role of the kidney in plasma cytokine removal in sepsis syndrome: A pilot study
    • Gruppo di Studio Trattamenti depurativi in area critica of the Italian Society of Nephrology
    • Graziani G, Bordone G, Bellato V, et al; Gruppo di Studio Trattamenti depurativi in area critica of the Italian Society of Nephrology: Role of the kidney in plasma cytokine removal in sepsis syndrome: a pilot study. J Nephrol 2006; 19:176-182
    • (2006) J Nephrol , vol.19 , pp. 176-182
    • Graziani, G.1    Bordone, G.2    Bellato, V.3
  • 7
    • 34548022149 scopus 로고    scopus 로고
    • Understanding the inflammatory cytokine response in pneumonia and sepsis: Results of the Genetic and Inflammatory Markers of Sepsis (GenIMS) Study
    • GenIMS Investigators
    • Kellum JA, Kong L, Fink MP, et al; GenIMS Investigators: Understanding the inflammatory cytokine response in pneumonia and sepsis: Results of the Genetic and Inflammatory Markers of Sepsis (GenIMS) Study. Arch Intern Med 2007; 167:1655-1663
    • (2007) Arch Intern Med , vol.167 , pp. 1655-1663
    • Kellum, J.A.1    Kong, L.2    Fink, M.P.3
  • 8
    • 0033969341 scopus 로고    scopus 로고
    • Pro-versus anti-inflammatory cytokine profile in patients with severe sepsis: A marker for prognosis and future therapeutic options
    • Gogos CA, Drosou E, Bassaris HP, et al: Pro-versus anti-inflammatory cytokine profile in patients with severe sepsis: A marker for prognosis and future therapeutic options. J Infect Dis 2000; 181:176-180
    • (2000) J Infect Dis , vol.181 , pp. 176-180
    • Gogos, C.A.1    Drosou, E.2    Bassaris, H.P.3
  • 9
    • 77957852137 scopus 로고    scopus 로고
    • Evaluation of the effects of pulse high-volume hemofiltration in patients with severe sepsis: A preliminary study
    • Peng Z, Pai P, Han-Min W, et al: Evaluation of the effects of pulse high-volume hemofiltration in patients with severe sepsis: A preliminary study. Int J Artif Organs 2010; 33:505-511
    • (2010) Int J Artif Organs , vol.33 , pp. 505-511
    • Peng, Z.1    Pai, P.2    Han-Min, W.3
  • 10
    • 62949184906 scopus 로고    scopus 로고
    • High-volume hemofiltration in sepsis and SIRS: Current concepts and future prospects
    • Honore PM, Joannes-Boyau O, Boer W, et al: High-volume hemofiltration in sepsis and SIRS: Current concepts and future prospects. Blood Purif 2009; 28:1-11
    • (2009) Blood Purif , vol.28 , pp. 1-11
    • Honore, P.M.1    Joannes-Boyau, O.2    Boer, W.3
  • 11
    • 49749084319 scopus 로고    scopus 로고
    • A pilot randomized study comparing high and low volume hemofiltration on vasopressor use in septic shock
    • Boussekey N, Chiche A, Faure K, et al: A pilot randomized study comparing high and low volume hemofiltration on vasopressor use in septic shock. Intensive Care Med 2008; 34:1646-1653
    • (2008) Intensive Care Med , vol.34 , pp. 1646-1653
    • Boussekey, N.1    Chiche, A.2    Faure, K.3
  • 12
    • 34147152344 scopus 로고    scopus 로고
    • A pilot study of high-adsorption hemofiltration in human septic shock
    • Haase M, Silvester W, Uchino S, et al: A pilot study of high-adsorption hemofiltration in human septic shock. Int J Artif Organs 2007; 30:108-117
    • (2007) Int J Artif Organs , vol.30 , pp. 108-117
    • Haase, M.1    Silvester, W.2    Uchino, S.3
  • 13
    • 33748111321 scopus 로고    scopus 로고
    • Pilot study on the effects of high cutoff hemofiltration on the need for norepinephrine in septic patients with acute renal failure
    • Morgera S, Haase M, Kuss T, et al: Pilot study on the effects of high cutoff hemofiltration on the need for norepinephrine in septic patients with acute renal failure. Crit Care Med 2006; 34:2099-2104
    • (2006) Crit Care Med , vol.34 , pp. 2099-2104
    • Morgera, S.1    Haase, M.2    Kuss, T.3
  • 14
    • 0036270678 scopus 로고    scopus 로고
    • A pilot study of coupled plasma filtration with adsorption in septic shock
    • Ronco C, Brendolan A, Lonnemann G, et al: A pilot study of coupled plasma filtration with adsorption in septic shock. Crit Care Med 2002; 30:1250-1255
    • (2002) Crit Care Med , vol.30 , pp. 1250-1255
    • Ronco, C.1    Brendolan, A.2    Lonnemann, G.3
  • 15
    • 0033710084 scopus 로고    scopus 로고
    • Prospective evaluation of short-term, high-volume isovolemic hemofiltration on the hemodynamic course and outcome in patients with intractable circulatory failure resulting from septic shock
    • Honore PM, Jamez J, Wauthier M, et al: Prospective evaluation of short-term, high-volume isovolemic hemofiltration on the hemodynamic course and outcome in patients with intractable circulatory failure resulting from septic shock. Crit Care Med 2000; 28:3581-3587
    • (2000) Crit Care Med , vol.28 , pp. 3581-3587
    • Honore, P.M.1    Jamez, J.2    Wauthier, M.3
  • 16
    • 33749127233 scopus 로고    scopus 로고
    • Serum IL-6 and IL-1-ra with sequential organ failure assessment scores in septic patients receiving high-volume haemofiltration and continuous venovenous haemofiltration
    • Ghani RA, Zainudin S, Ctkong N, et al: Serum IL-6 and IL-1-ra with sequential organ failure assessment scores in septic patients receiving high-volume haemofiltration and continuous venovenous haemofiltration. Nephrology (Carlton) 2006; 11:386-393
    • (2006) Nephrology (Carlton) , vol.11 , pp. 386-393
    • Ghani, R.A.1    Zainudin, S.2    Ctkong, N.3
  • 17
    • 0036154952 scopus 로고    scopus 로고
    • A phase II randomized, controlled trial of continuous hemofiltration in sepsis
    • Cole L, Bellomo R, Hart G, et al: A phase II randomized, controlled trial of continuous hemofiltration in sepsis. Crit Care Med 2002; 30:100-106
    • (2002) Crit Care Med , vol.30 , pp. 100-106
    • Cole, L.1    Bellomo, R.2    Hart, G.3
  • 18
    • 0029914622 scopus 로고    scopus 로고
    • Assessing the quality of reports of randomized clinical trials: Is blinding necessary?
    • Jadad AR, Moore RA, Carroll D, et al: Assessing the quality of reports of randomized clinical trials: Is blinding necessary? Control Clin Trials 1996; 17:1-12
    • (1996) Control Clin Trials , vol.17 , pp. 1-12
    • Jadad, A.R.1    Moore, R.A.2    Carroll, D.3
  • 19
    • 77955171857 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
    • PRISMA Group
    • Moher D, Liberati A, Tetzlaff J, et al; PRISMA Group: Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. Int J Surg 2010; 8:336-341
    • (2010) Int J Surg , vol.8 , pp. 336-341
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3
  • 20
    • 0041876133 scopus 로고    scopus 로고
    • Measuring inconsistency in meta-analyses
    • Higgins JP, Thompson SG, Deeks JJ, et al: Measuring inconsistency in meta-analyses. BMJ 2003; 327:557-560
    • (2003) BMJ , vol.327 , pp. 557-560
    • Higgins, J.P.1    Thompson, S.G.2    Deeks, J.J.3
  • 22
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M, Davey Smith G, Schneider M, et al: Bias in meta-analysis detected by a simple, graphical test. BMJ 1997; 315:629-634
    • (1997) BMJ , vol.315 , pp. 629-634
    • Egger, M.1    Davey Smith, G.2    Schneider, M.3
  • 23
    • 78651519727 scopus 로고    scopus 로고
    • Removal of humoral mediators and the effect on the survival of septic patients by hemoperfusion with neutral microporous resin column
    • Huang Z, Wang SR, Su W, et al: Removal of humoral mediators and the effect on the survival of septic patients by hemoperfusion with neutral microporous resin column. Ther Apher Dial 2010; 14:596-602
    • (2010) Ther Apher Dial , vol.14 , pp. 596-602
    • Huang, Z.1    Wang, S.R.2    Su, W.3
  • 24
    • 21344446832 scopus 로고    scopus 로고
    • Removal of inflammatory cytokines and endotoxin by veno-venous continuous renal replacement therapy for burned patients with sepsis
    • Peng Y, Yuan Z, Li H: Removal of inflammatory cytokines and endotoxin by veno-venous continuous renal replacement therapy for burned patients with sepsis. Burns 2005; 31:623-628
    • (2005) Burns , vol.31 , pp. 623-628
    • Peng, Y.1    Yuan, Z.2    Li, H.3
  • 25
    • 4644275722 scopus 로고    scopus 로고
    • Effect of polymyxin B-immobilized fiber on bone resorption in patients with sepsis
    • Nakamura T, Kawagoe Y, Matsuda T, et al: Effect of polymyxin B-immobilized fiber on bone resorption in patients with sepsis. Intensive Care Med 2004; 30:1838-1841
    • (2004) Intensive Care Med , vol.30 , pp. 1838-1841
    • Nakamura, T.1    Kawagoe, Y.2    Matsuda, T.3
  • 26
    • 0346014860 scopus 로고    scopus 로고
    • Hemoperfusion with polymyxin B-immobilized fiber in septic patients with methicillin-resistant Staphylococcus aureus-associated glomerulonephritis
    • Nakamura T, Ushiyama C, Suzuki Y, et al: Hemoperfusion with polymyxin B-immobilized fiber in septic patients with methicillin-resistant Staphylococcus aureus-associated glomerulonephritis. Nephron Clin Pract 2003; 94:c33-c39
    • (2003) Nephron Clin Pract , vol.94
    • Nakamura, T.1    Ushiyama, C.2    Suzuki, Y.3
  • 27
    • 0346142713 scopus 로고    scopus 로고
    • Combination therapy with polymyxin B-immobilized fibre haemoperfusion and teicoplanin for sepsis due to methicillin-resistant Staphylococcus aureus
    • Nakamura T, Ushiyama C, Suzuki Y, et al: Combination therapy with polymyxin B-immobilized fibre haemoperfusion and teicoplanin for sepsis due to methicillin-resistant Staphylococcus aureus. J Hosp Infect 2003; 53:58-63
    • (2003) J Hosp Infect , vol.53 , pp. 58-63
    • Nakamura, T.1    Ushiyama, C.2    Suzuki, Y.3
  • 28
    • 0036389976 scopus 로고    scopus 로고
    • Plasmapheresis in severe sepsis and septic shock: A prospective, randomised, controlled trial
    • Busund R, Koukline V, Utrobin U, et al: Plasmapheresis in severe sepsis and septic shock: A prospective, randomised, controlled trial. Intensive Care Med 2002; 28:1434-1439
    • (2002) Intensive Care Med , vol.28 , pp. 1434-1439
    • Busund, R.1    Koukline, V.2    Utrobin, U.3
  • 29
    • 0036559045 scopus 로고    scopus 로고
    • Hemoperfusion with polymyxin B immobilized fibers for urinary albumin excretion in septic patients with trauma
    • Nakamura T, Ushiyama C, Suzuki Y, et al: Hemoperfusion with polymyxin B immobilized fibers for urinary albumin excretion in septic patients with trauma. ASAIO J 2002; 48:244-248
    • (2002) ASAIO J , vol.48 , pp. 244-248
    • Nakamura, T.1    Ushiyama, C.2    Suzuki, Y.3
  • 30
    • 0035742403 scopus 로고    scopus 로고
    • Newly developed immobilized polymyxin B fibers improve the survival of patients with sepsis
    • Nemoto H, Nakamoto H, Okada H, et al: Newly developed immobilized polymyxin B fibers improve the survival of patients with sepsis. Blood Purif 2001; 19:361-369
    • (2001) Blood Purif , vol.19 , pp. 361-369
    • Nemoto, H.1    Nakamoto, H.2    Okada, H.3
  • 31
    • 67649219652 scopus 로고    scopus 로고
    • Early use of polymyxin B hemoperfusion in abdominal septic shock: The EUPHAS randomized controlled trial
    • Cruz DN, Antonelli M, Fumagalli R, et al: Early use of polymyxin B hemoperfusion in abdominal septic shock: The EUPHAS randomized controlled trial. JAMA 2009; 301:2445-2452
    • (2009) JAMA , vol.301 , pp. 2445-2452
    • Cruz, D.N.1    Antonelli, M.2    Fumagalli, R.3
  • 32
    • 62849107393 scopus 로고    scopus 로고
    • Impact of continuous venovenous hemofiltration on organ failure during the early phase of severe sepsis: A randomized controlled trial
    • Hemofiltration and Sepsis Group of the Collège National de Réanimation et de Médecine d'Urgence des Hôpitaux extra-Universitaires
    • Payen D, Mateo J, Cavaillon JM, et al; Hemofiltration and Sepsis Group of the Collège National de Réanimation et de Médecine d'Urgence des Hôpitaux extra-Universitaires: Impact of continuous venovenous hemofiltration on organ failure during the early phase of severe sepsis: A randomized controlled trial. Crit Care Med 2009; 37:803-810
    • (2009) Crit Care Med , vol.37 , pp. 803-810
    • Payen, D.1    Mateo, J.2    Cavaillon, J.M.3
  • 33
    • 20244379132 scopus 로고    scopus 로고
    • A pilot-controlled study of a polymyxin B-immobilized hemoperfusion cartridge in patients with severe sepsis secondary to intra-abdominal infection
    • Vincent JL, Laterre PF, Cohen J, et al: A pilot-controlled study of a polymyxin B-immobilized hemoperfusion cartridge in patients with severe sepsis secondary to intra-abdominal infection. Shock 2005; 23:400-405
    • (2005) Shock , vol.23 , pp. 400-405
    • Vincent, J.L.1    Laterre, P.F.2    Cohen, J.3
  • 34
    • 3943092597 scopus 로고    scopus 로고
    • Open randomized phase II trial of an extracorporeal endotoxin adsorber in suspected Gram-negative sepsis
    • EASy-Study Group
    • Reinhart K, Meier-Hellmann A, Beale R, et al; EASy-Study Group: Open randomized phase II trial of an extracorporeal endotoxin adsorber in suspected Gram-negative sepsis. Crit Care Med 2004; 32:1662-1668
    • (2004) Crit Care Med , vol.32 , pp. 1662-1668
    • Reinhart, K.1    Meier-Hellmann, A.2    Beale, R.3
  • 35
    • 0032706914 scopus 로고    scopus 로고
    • Continuous plasmafiltration in sepsis syndrome
    • Plasmafiltration in Sepsis Study Group
    • Reeves JH, Butt WW, Shann F, et al: Continuous plasmafiltration in sepsis syndrome. Plasmafiltration in Sepsis Study Group. Crit Care Med 1999; 27:2096-2104
    • (1999) Crit Care Med , vol.27 , pp. 2096-2104
    • Reeves, J.H.1    Butt, W.W.2    Shann, F.3
  • 36
    • 0032929237 scopus 로고    scopus 로고
    • Treatment with polymyxin B-immobilized fiber reduces platelet activation in septic shock patients: Decrease in plasma levels of soluble P-selectin, platelet factor 4 and beta-thromboglobulin
    • Nakamura T, Ebihara I, Shoji H, et al: Treatment with polymyxin B-immobilized fiber reduces platelet activation in septic shock patients: Decrease in plasma levels of soluble P-selectin, platelet factor 4 and beta-thromboglobulin. Inflamm Res 1999; 48:171-175
    • (1999) Inflamm Res , vol.48 , pp. 171-175
    • Nakamura, T.1    Ebihara, I.2    Shoji, H.3
  • 37
    • 0026710191 scopus 로고
    • Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
    • The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine
    • Bone RC, Balk RA, Cerra FB, et al: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 1992; 101:1644-1655
    • (1992) Chest , vol.101 , pp. 1644-1655
    • Bone, R.C.1    Balk, R.A.2    Cerra, F.B.3
  • 38
    • 33646416536 scopus 로고    scopus 로고
    • High-volume hemofiltration as salvage therapy in severe hyperdynamic septic shock
    • Cornejo R, Downey P, Castro R, et al: High-volume hemofiltration as salvage therapy in severe hyperdynamic septic shock. Intensive Care Med 2006; 32:713-722
    • (2006) Intensive Care Med , vol.32 , pp. 713-722
    • Cornejo, R.1    Downey, P.2    Castro, R.3
  • 39
    • 0034032811 scopus 로고    scopus 로고
    • The effect of intensive plasma water exchange by hemofiltration on hemodynamics and soluble mediators in canine endotoxemia
    • Bellomo R, Kellum JA, Gandhi CR, et al: The effect of intensive plasma water exchange by hemofiltration on hemodynamics and soluble mediators in canine endotoxemia. Am J Respir Crit Care Med 2000; 161:1429-1436
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 1429-1436
    • Bellomo, R.1    Kellum, J.A.2    Gandhi, C.R.3
  • 40
    • 77953315524 scopus 로고    scopus 로고
    • Intensities of renal replacement therapy in acute kidney injury: A systematic review and metaanalysis
    • Jun M, Heerspink HJ, Ninomiya T, et al: Intensities of renal replacement therapy in acute kidney injury: A systematic review and metaanalysis. Clin J Am Soc Nephrol 2010; 5:956-963
    • (2010) Clin J Am Soc Nephrol , vol.5 , pp. 956-963
    • Jun, M.1    Heerspink, H.J.2    Ninomiya, T.3
  • 41
    • 77951621355 scopus 로고    scopus 로고
    • High-dose renal replacement therapy for acute kidney injury: Systematic review and meta-analysis
    • University of Toronto Acute Kidney Injury Research Group
    • Van Wert R, Friedrich JO, Scales DC, et al; University of Toronto Acute Kidney Injury Research Group: High-dose renal replacement therapy for acute kidney injury: Systematic review and meta-analysis. Crit Care Med 2010; 38:1360-1369
    • (2010) Crit Care Med , vol.38 , pp. 1360-1369
    • Van Wert, R.1    Friedrich, J.O.2    Scales, D.C.3
  • 42
    • 84856456910 scopus 로고    scopus 로고
    • Acute removal of common sepsis mediators does not explain the effects of extracorporeal blood purification in experimental sepsis
    • Peng ZY, Wang HZ, Carter MJ, et al: Acute removal of common sepsis mediators does not explain the effects of extracorporeal blood purification in experimental sepsis. Kidney Int 2012; 81:363-369
    • (2012) Kidney Int , vol.81 , pp. 363-369
    • Peng, Z.Y.1    Wang, H.Z.2    Carter, M.J.3
  • 43
    • 84255194001 scopus 로고    scopus 로고
    • Immunosuppression in patients who die of sepsis and multiple organ failure
    • Boomer JS, To K, Chang KC, et al: Immunosuppression in patients who die of sepsis and multiple organ failure. JAMA 2011; 306:2594-2605
    • (2011) JAMA , vol.306 , pp. 2594-2605
    • Boomer, J.S.1    To, K.2    Chang, K.C.3
  • 44
    • 69349100966 scopus 로고    scopus 로고
    • The 90-day mortality and the subsequent renal recovery in critically ill surgical patients requiring acute renal replacement therapy
    • NSARF Study Group
    • Lin YF, Ko WJ, Chu TS, et al; NSARF Study Group: The 90-day mortality and the subsequent renal recovery in critically ill surgical patients requiring acute renal replacement therapy. Am J Surg 2009; 198:325-332
    • (2009) Am J Surg , vol.198 , pp. 325-332
    • Lin, Y.F.1    Ko, W.J.2    Chu, T.S.3
  • 45
    • 45549087193 scopus 로고    scopus 로고
    • Predictors of mortality in a cohort of intensive care unit patients with acute renal failure receiving continuous renal replacement therapy
    • Brar H, Olivier J, Lebrun C, et al: Predictors of mortality in a cohort of intensive care unit patients with acute renal failure receiving continuous renal replacement therapy. Am J Med Sci 2008; 335:342-347
    • (2008) Am J Med Sci , vol.335 , pp. 342-347
    • Brar, H.1    Olivier, J.2    Lebrun, C.3
  • 46
    • 38349084071 scopus 로고    scopus 로고
    • Effectiveness of continuous hemodiafiltration using a polymethylmethacrylate membrane hemofilter after polymyxin B-immobilized fiber column therapy of septic shock
    • Sakamoto Y, Mashiko K, Obata T, et al: Effectiveness of continuous hemodiafiltration using a polymethylmethacrylate membrane hemofilter after polymyxin B-immobilized fiber column therapy of septic shock. ASAIO J 2008; 54:129-132
    • (2008) ASAIO J , vol.54 , pp. 129-132
    • Sakamoto, Y.1    Mashiko, K.2    Obata, T.3
  • 47
    • 33644989975 scopus 로고    scopus 로고
    • Combining continuous endotoxin apheresis and continuous hemodiafiltration in the treatment of patients with septic multiple organ dysfunction syndrome
    • Yonekawa C, Nakae H, Tajimi K, et al: Combining continuous endotoxin apheresis and continuous hemodiafiltration in the treatment of patients with septic multiple organ dysfunction syndrome. Ther Apher Dial 2006; 10:19-24
    • (2006) Ther Apher Dial , vol.10 , pp. 19-24
    • Yonekawa, C.1    Nakae, H.2    Tajimi, K.3
  • 48
    • 1842376945 scopus 로고    scopus 로고
    • Discrepancies between meta-analyses and subsequent large randomized, controlled trials
    • LeLorier J, Grégoire G, Benhaddad A, et al: Discrepancies between meta-analyses and subsequent large randomized, controlled trials. N Engl J Med 1997; 337:536-542
    • (1997) N Engl J Med , vol.337 , pp. 536-542
    • Lelorier, J.1    Grégoire, G.2    Benhaddad, A.3
  • 49
    • 67649219642 scopus 로고    scopus 로고
    • International differences in the treatment of sepsis: Are they justified?
    • Kellum JA, Uchino S: International differences in the treatment of sepsis: Are they justified? JAMA 2009; 301:2496-2497
    • (2009) JAMA , vol.301 , pp. 2496-2497
    • Kellum, J.A.1    Uchino, S.2
  • 50
    • 46149116065 scopus 로고    scopus 로고
    • Pharmacokinetics of meropenem during intermittent and continuous intravenous application in patients treated by continuous renal replacement therapy
    • Langgartner J, Vasold A, Glück T, et al: Pharmacokinetics of meropenem during intermittent and continuous intravenous application in patients treated by continuous renal replacement therapy. Intensive Care Med 2008; 34:1091-1096
    • (2008) Intensive Care Med , vol.34 , pp. 1091-1096
    • Langgartner, J.1    Vasold, A.2    Glück, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.