Enhancement of lipid production in low-starch mutants Chlamydomonas reinhardtii by adaptive laboratory evolution

Bioresource Technology

Volumn 147, Issue , 2013, Pages 499-507

  Yu, Shuiyan ^a   Zhao, Quanyu ^a   Miao, Xiaoling ^b   Shi, Jiping ^a  

^a SHANGHAI ADVANCED RESEARCH INSTITUTE   (China)

^b Shanghai Jiao Tong University   (China)

Author keywords

Adaptive laboratory evolution; Chlamydomonas reinhardtii; Lipid productivity; Low starch mutant; Nitrogen starvation

Indexed keywords

ECOLOGY; NITROGEN; PRODUCTIVITY;

ADAPTIVE LABORATORY EVOLUTION; CHLAMYDOMONAS REINHARDTII; LIPID PRODUCTIVITIES; LOW-STARCH MUTANT; NITROGEN STARVATION;

STARCH;

LIPID; NITROGEN; STARCH;

BIOMASS; GROWTH RATE; LABORATORY METHOD; LIPID; MICROALGA; NITROGEN; PHENOTYPE; STARCH;

ADAPTIVE LABORATORY EVOLUTION; ALGAL GROWTH; ARTICLE; BIOMASS; CELL DENSITY; CHLAMYDOMONAS REINHARDTII; CONTROLLED STUDY; GENETIC ENGINEERING; GROWTH RATE; LIPID ANALYSIS; LIPID STORAGE; MICROBIOLOGICAL PARAMETERS; MOLECULAR EVOLUTION; NONHUMAN; PHENOTYPE; PHOTOSYNTHESIS; PRIORITY JOURNAL; PRODUCTIVITY; QUANTUM YIELD; STRAIN IMPROVEMENT; SYNTHETIC BIOLOGY;

CHLAMYDOMONAS REINHARDTII;

ADAPTIVE LABORATORY EVOLUTION; CHLAMYDOMONAS REINHARDTII; LIPID PRODUCTIVITY; LOW-STARCH MUTANT; NITROGEN STARVATION;

CHLAMYDOMONAS REINHARDTII; LIPIDS; STARCH;

EID: 84883649565     PISSN: 09608524     EISSN: 18732976     Source Type: Journal    
DOI: 10.1016/j.biortech.2013.08.069     Document Type: Article

References (34)

1. Baker N.R., Oxoborough K. Chlorophyll fluorescence as a probe of photosynthetic productivity. Chlorophyll A Fluorescence: A Signature of Photosynthesis 2004, 65-82. Springer, The Netherlands. G.C. Papageorgiou, Govindjee (Eds.).
2. Ball S., Marianne T., Dirick L., Fresnoy M., Delrue B., Decq A. A Chlamydomonas reinhardtii low-starch mutant is defective for 3-phosphoglycerate activation and orthophosphate inhibition of ADP-glucose pyrophosphorylase. Planta 1991, 185(1):17-26.
3. Ball S.G., Morell M.K. From bacterial glycogen to starch: understanding the biogenesis of the plant starch granule. Annu. Rev. Plant Biol. 2003, 54:207-233.
4. Ballin G., Doucha J., Zachleder V. Macromolecular syntheses and the course of cell cycle events in the chlorococcal alga Scenedesmus quadricauda under nutrient starvation: effect of nitrogen starvation. Biol. Plant 1988, 20:81-91.
5. Breuer G., Lamers P.P., Martens D.E., Draaisma R.B., Wijffels R.H. The impact of nitrogen starvation on the dynamics of triacylglycerol accumulation in nine microalgae strains. Bioresour. Technol. 2012, 124:217-226.
6. Cheirsilp B., Torpee S. Enhanced growth and lipid production of microalgae under mixotrophic culture condition: effect of light intensity, glucose concentration and fed-batch cultivation. Bioresour. Technol. 2012, 110:510-516.
7. Converti A., Casazza A.A., Ortiz E.Y., Perego P., Borghi M.D. Effect of temperature and nitrogen concentration on the growth and lipid content of Nannochloropsis oculata and Chlorella vulgaris for biodiesel production. Chem. Eng. Process. 2009, 48(6):1146-1151.
8. da Silva A.F., Lourenco S.O., Chaloub R.M. Effects of nitrogen starvation on the photosynthetic physiology of a tropical marine microalga Rhodomonas sp. (Cryptophyceae). Aquat. Bot. 2009, 91(4):291-297.
9. Doan T.T.Y., Sivaloganathan B., Obbard J.P. Screening of marine microalgae for biodiesel feedstock. Biomass Bioenergy 2011, 35(7):2534-2544.
10. Folch J., Lees M., Stanley G.H.S. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 1957, 226:497-509.
11. Fu W.Q., Gudmundsson O., Feist A.M., Herjolfsson G., Brynjolfsson S., Palsson B. Maximizing biomass productivity and cell density of Chlorella vulgaris by using light-emitting diode-based photobioreactor. J. Biotechnol. 2012, 161:242-249.
12. Fu W.Q., Gudmundsson O., Paglia G., Herjolfsson G., Andresson Q.S., Palsson B.O., Brynjolfsson S. Enhancement of carotenoid biosynthesis in the green microalga Dunaliella salina with light-emitting diodes and adaptive laboratory evolution. Appl. Microbiol. Biotechnol. 2013, 97:2395-2403.
13. Geider R., LaRoche J., Greene R.M., Olaizola M. Response of the photosynthetic apparatus of Phaeodactylum tricornutum (Bacillariophyceae) to nitrate, phosphate, or iron starvation. J. Phycol. 1993, 29:755-766.
14. Geider R., Macintyre H.L., Graciano L.M., McKay R.M.L. Response of the photosynthetic apparatus of Dunaliella tertiolecta (Chlorophyceae) to nitrogen and phosphorus limitation. Eur. J. Phycol. 1998, 33:315-332.
15. Griffiths M.J., Harrison S.T.L. Lipid productivity as a key characteristic for choosing algal species for biodiesel production. J. Appl. Phycol. 2009, 21:493-507.
16. Harris E.H. Chlamydomonas as a model organism. Annu. Rev. Plant Physiol. Plant Mol. Biol. 2001, 52:363-406.
17. Hu Q., Sommerfeld M., Jarvis E., Ghirardi M., Posewitz M., Seibert M., Darzins A. Microalgal triacylglycerols as feedstocks for biofuel production: perspectives and advances. J. Plant 2008, 54(4):621-639.
18. Kolber Z., Zher J., Falkowski P.G. Effects of growth irradiance and nitrogen limitation on photosynthetic energy conversion in photosystem II. Plant Physiol. 1988, 88:923-929.
19. Larson T.R., Rees T.A.V. Changes in cell composition and lipid metabolism mediated by sodium and nitrogen availability in the marine diatom Phaeodactylum tricornutum (Bacillariophyceae). J. Phycol. 1996, 32:388-393.
20. Li Y., Han D., Hu G., Dauvillee D., Sommerfeld M., Ball S., Hu Q. Chlamydomonas starchless mutant defective in ADP-glucose pyrophosphorylase hyper-accumulates triacylglycerol. Metab. Eng. 2010, 12:387-391.
21. Li Y., Han D., Hu G., Sommerfeld M., Hu Q. Inhibition of starch synthesis results in overproduction of lipids in Chlamydomonas reinhardtii. Biotechnol. Bioeng. 2010, 107(2):258-268.
22. Maxwell K., Johnson G.N. Chlorophyll fluorescence-a practical guide. J. Exp. Bot. 2000, 51(345):659-668.
23. Mouille G., Maddelein M.L., Libessart N., Talaga P., Decq A., Delrue B., Ball S. Preamylopectin processing: a mandatory step for starch biosynthesis in plants. Plant Cell 1996, 8(8):1353-1366.
24. Msanne J., Xu D., Konda A.R., Casas-Mollano J.A., Awada T., Cahoon E.B., Cerutti H. Metabolic and gene expression changes triggered by nitrogen deprivation in the photoautotrophically grown microalgae Chlamydomonas reinhardtii and Coccomyxa sp. C-169. Phytochemistry 2012, 75:50-59.
25. Muller P., Li X.P., Niyogi K.K. Non-photochemical quenching. A response to excess light energy. Plant Physiol. 2001, 125(4):1558-1566.
26. Palsson B.O. Adaptive laboratory evolution. Microbe 2011, 6(2):69-74.
27. Parkhill J.P., Maillet G., Cullen J.J. Fluorescence-based maximal quantum yield for as a diagnostic of nutrient stress. J. Phycol. 2001, 37:517-529.
28. Peterson R.B., Hanson K.R. Changes in photochemical and fluorescence yields in leaf tissue from normal and starchless Nicotiana sylvestris with increasing irradiance. Plant Science 1991, 76(2):143-151.
29. Portnoy V.A., Bezdan D., Zengler K. Adaptive laboratory evolution-harnessing the power of biology for metabolic engineering. Curr. Opin. Biotechnol. 2011, 22(4):590-594.
30. Van Den Koornhuyse N., Libessart N., Delrue B., Zabawinski C., Decq A., Iglesias A., Carton A., Preiss J., Ball S. Control of starch composition and structure through substrate supply in the monocellular alga Chlamydomonas reinhardtii. J. Biol. Chem. 1996, 271(27):16281-16287.
31. Wang Z.T., Ullrich N., Joo S., Waffenschmidt S., Goodenough U. Algal lipid bodies: stress induction, purification, and biochemical characterization in wild-type and starchless Chlamydomonas reinhardtii. Eukaryot. Cell 2009, 8(12):1856-1868.
32. Work V.H., Radakovits R., Jinkerson R.E., Meuser J.E., Elliott L.G., Vinyard D.J., Laurens L.M.L., Dismukes G.C., Matthew C.P. Increased lipid accumulation in the Chlamydomonas reinhardtii sta7-10 starchless isoamylase mutant and increased carbohydrate synthesis in complemented strains. Eukaryot. Cell 2010, 9(8):1251-1261.
33. Yeesang C., Cheirsilp B. Effect of nitrogen, salt, and iron content in the growth medium and light intensity on lipid production by microalgae isolated from fresh water sources in Thailand. Bioresour. Technol. 2011, 102(3):3034-3040.
34. Zhou W., Li Y., Min M., Hu B., Chen P., Ruan R. Local bioprospecting for high-lipid producing microalgal strains to be grown on concentrated municipal wastewater for biofuel production. Bioresour. Technol. 2011, 102:6909-6919.