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Volumn 186, Issue , 2013, Pages 43-48

Ghrelin stimulates synaptic formation in cultured cortical networks in a dose-dependent manner

Author keywords

Dissociated cortical neurons; Ghrelin; GHSR1; Newborn rats; Synaptogenesis

Indexed keywords

GHRELIN; GHRELIN RECEPTOR; GHRELIN RECEPTOR 1; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

EID: 84883619772     PISSN: 01670115     EISSN: 18731686     Source Type: Journal    
DOI: 10.1016/j.regpep.2013.07.004     Document Type: Article
Times cited : (22)

References (57)
  • 1
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima M., Hosada H., Date Y., Nakazato M., Matsuo H., Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999, 402:656-660.
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosada, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 4
    • 29044434688 scopus 로고    scopus 로고
    • Expression of ghrelin receptor mRNA in the rat and the mouse brain
    • Zigman J.M., Jones J.E., Lee C.E., Saper C.B., Elmquist J.K. Expression of ghrelin receptor mRNA in the rat and the mouse brain. J Comp Neurol 2006, 494(3):528-548.
    • (2006) J Comp Neurol , vol.494 , Issue.3 , pp. 528-548
    • Zigman, J.M.1    Jones, J.E.2    Lee, C.E.3    Saper, C.B.4    Elmquist, J.K.5
  • 5
    • 0035863948 scopus 로고    scopus 로고
    • Comparative distribution of mRNA encoding the growth hormone secretagogue-receptor (GHS-R) in Microcebus murinus (Primate, lemurian) and rat forebrain and pituitary
    • Mitchell V., Bouret S., Beauvillain J.C., Schilling A., Perret M., Kordon C., Epelbaum J. Comparative distribution of mRNA encoding the growth hormone secretagogue-receptor (GHS-R) in Microcebus murinus (Primate, lemurian) and rat forebrain and pituitary. J Comp Neurol 2001, 429(3):469-489.
    • (2001) J Comp Neurol , vol.429 , Issue.3 , pp. 469-489
    • Mitchell, V.1    Bouret, S.2    Beauvillain, J.C.3    Schilling, A.4    Perret, M.5    Kordon, C.6    Epelbaum, J.7
  • 7
    • 78650743194 scopus 로고    scopus 로고
    • The extra-hypothalamic actions of ghrelin on neuronal function
    • Andrews Z.B. The extra-hypothalamic actions of ghrelin on neuronal function. Trends Neurosci 2011, 34(1):31-40.
    • (2011) Trends Neurosci , vol.34 , Issue.1 , pp. 31-40
    • Andrews, Z.B.1
  • 8
    • 81755184766 scopus 로고    scopus 로고
    • Role of ghrelin system in neuroprotection and cognitive functions: implications in Alzheimer's disease
    • Gahete M.D., Córdoba-Chacón J., Kineman R.D., Luque R.M., Castaño J.P. Role of ghrelin system in neuroprotection and cognitive functions: implications in Alzheimer's disease. Peptides 2011, 32(11):2225-2228.
    • (2011) Peptides , vol.32 , Issue.11 , pp. 2225-2228
    • Gahete, M.D.1    Córdoba-Chacón, J.2    Kineman, R.D.3    Luque, R.M.4    Castaño, J.P.5
  • 9
    • 77954898609 scopus 로고    scopus 로고
    • Inhibition of apoptotic cell death by ghrelin improves functional recovery after spinal cord injury
    • Lee J.Y., Chung H., Yoo Y.S., Oh Y.J., Oh T.H., Park S., Yune T.Y. Inhibition of apoptotic cell death by ghrelin improves functional recovery after spinal cord injury. Endocrinology 2010, 151(8):3815-3826.
    • (2010) Endocrinology , vol.151 , Issue.8 , pp. 3815-3826
    • Lee, J.Y.1    Chung, H.2    Yoo, Y.S.3    Oh, Y.J.4    Oh, T.H.5    Park, S.6    Yune, T.Y.7
  • 12
    • 0037471360 scopus 로고    scopus 로고
    • Existence of ghrelin-immunopositive and -expressing cells in the proventriculus of the hatching and adult chicken
    • Wada R., Sakata I., Kaiya H., Nakamura K., Hayashi Y., Kangawa K., Sakai T. Existence of ghrelin-immunopositive and -expressing cells in the proventriculus of the hatching and adult chicken. Regul Pept 2003, 111(1-3):123-128.
    • (2003) Regul Pept , vol.111 , Issue.1-3 , pp. 123-128
    • Wada, R.1    Sakata, I.2    Kaiya, H.3    Nakamura, K.4    Hayashi, Y.5    Kangawa, K.6    Sakai, T.7
  • 13
    • 33646190291 scopus 로고    scopus 로고
    • Ghrelin-containing neuron in cerebral cortex and hypothalamus linked with the DVC of brainstem in rat
    • Hou Z., Miao Y., Gao L., Pan H., Zhu S. Ghrelin-containing neuron in cerebral cortex and hypothalamus linked with the DVC of brainstem in rat. Regul Pept 2006, 134(2-3):126-131.
    • (2006) Regul Pept , vol.134 , Issue.2-3 , pp. 126-131
    • Hou, Z.1    Miao, Y.2    Gao, L.3    Pan, H.4    Zhu, S.5
  • 15
    • 70349748437 scopus 로고    scopus 로고
    • Time-dependent changes in ghrelin-immunoreactivity in dissociated neuronal cultures of the newborn rat neocortex
    • Stoyanova I.I., Wiertz R.W., Rutten W.L. Time-dependent changes in ghrelin-immunoreactivity in dissociated neuronal cultures of the newborn rat neocortex. Regul Pept 2009, 158(1-3):86-90.
    • (2009) Regul Pept , vol.158 , Issue.1-3 , pp. 86-90
    • Stoyanova, I.I.1    Wiertz, R.W.2    Rutten, W.L.3
  • 16
    • 79959846783 scopus 로고    scopus 로고
    • Postprandial ghrelin response is reduced in patients with Parkinson's disease and idiopathic REM sleep behavior disorder: a peripheral biomarker for early Parkinson's disease?
    • Unger M.M., Möller J.C., Mankel K., Eggert K.M., Bohne K., Bodden M., Stiasny-Kolster K., Kann P.H., Mayer G., Tebbe J.J., Oertel W.H. Postprandial ghrelin response is reduced in patients with Parkinson's disease and idiopathic REM sleep behavior disorder: a peripheral biomarker for early Parkinson's disease?. J Neurol 2011, 258(6):982-990.
    • (2011) J Neurol , vol.258 , Issue.6 , pp. 982-990
    • Unger, M.M.1    Möller, J.C.2    Mankel, K.3    Eggert, K.M.4    Bohne, K.5    Bodden, M.6    Stiasny-Kolster, K.7    Kann, P.H.8    Mayer, G.9    Tebbe, J.J.10    Oertel, W.H.11
  • 17
    • 67349224088 scopus 로고    scopus 로고
    • Intraamygdaloid microinjection of acylated-ghrelin influences passive avoidance learning
    • Tóth K., László K., Lukács E., Lénárd L. Intraamygdaloid microinjection of acylated-ghrelin influences passive avoidance learning. Behav Brain Res 2009, 202(2):308-311.
    • (2009) Behav Brain Res , vol.202 , Issue.2 , pp. 308-311
    • Tóth, K.1    László, K.2    Lukács, E.3    Lénárd, L.4
  • 18
    • 71349086636 scopus 로고    scopus 로고
    • Role of intraamygdaloid acylated-ghrelin in spatial learning
    • Tóth K., László K., Lénárd L. Role of intraamygdaloid acylated-ghrelin in spatial learning. Brain Res Bull 2010, 81(1):33-37.
    • (2010) Brain Res Bull , vol.81 , Issue.1 , pp. 33-37
    • Tóth, K.1    László, K.2    Lénárd, L.3
  • 19
    • 73449090824 scopus 로고    scopus 로고
    • Ghrelin gene products and the regulation of food intake and gut motility
    • Chen C.Y., Asakawa A., Fujimiya M., Lee S.D., Inui A. Ghrelin gene products and the regulation of food intake and gut motility. Pharmacol Rev 2009, 61:430-481.
    • (2009) Pharmacol Rev , vol.61 , pp. 430-481
    • Chen, C.Y.1    Asakawa, A.2    Fujimiya, M.3    Lee, S.D.4    Inui, A.5
  • 20
    • 0036218881 scopus 로고    scopus 로고
    • Bluet-Pajot MTUltradian rhythmicity of ghrelin secretion in relation with GH, feeding behavior, and sleep-wake patterns in rats
    • Tolle V., Bassant M.H., Zizzari P., Poindessous-Jazat F., Tomasetto C., Epelbaum J. Bluet-Pajot MTUltradian rhythmicity of ghrelin secretion in relation with GH, feeding behavior, and sleep-wake patterns in rats. Endocrinology 2002, 143:1353-1361.
    • (2002) Endocrinology , vol.143 , pp. 1353-1361
    • Tolle, V.1    Bassant, M.H.2    Zizzari, P.3    Poindessous-Jazat, F.4    Tomasetto, C.5    Epelbaum, J.6
  • 21
    • 79952200111 scopus 로고    scopus 로고
    • Mechanisms underlying autoimmune synaptic encephalitis leading to disorders of memory, behavior and cognition: insights from molecular, cellular and synaptic studies
    • Moscato E.H., Jain A., Peng X., Hughes E.G., Dalmau J., Balice-Gordon R.J. Mechanisms underlying autoimmune synaptic encephalitis leading to disorders of memory, behavior and cognition: insights from molecular, cellular and synaptic studies. Eur J Neurosci 2010, 32(2):298-309.
    • (2010) Eur J Neurosci , vol.32 , Issue.2 , pp. 298-309
    • Moscato, E.H.1    Jain, A.2    Peng, X.3    Hughes, E.G.4    Dalmau, J.5    Balice-Gordon, R.J.6
  • 22
    • 0031613853 scopus 로고    scopus 로고
    • Brain plasticity and behavior
    • Kolb B., Whishaw I.Q. Brain plasticity and behavior. Annu Rev Psychol 1998, 49:43-64.
    • (1998) Annu Rev Psychol , vol.49 , pp. 43-64
    • Kolb, B.1    Whishaw, I.Q.2
  • 23
    • 0037044699 scopus 로고    scopus 로고
    • Learning-induced multiple synapse formation in rat cerebellar cortex
    • Federmeier K.D., Kleim J.A., Greenough W.T. Learning-induced multiple synapse formation in rat cerebellar cortex. Neurosci Lett 2002, 332:180-184.
    • (2002) Neurosci Lett , vol.332 , pp. 180-184
    • Federmeier, K.D.1    Kleim, J.A.2    Greenough, W.T.3
  • 24
    • 0029902028 scopus 로고    scopus 로고
    • Synaptogenesis and Fos expression in the motor cortex of the adult rat after motor skill learning
    • Kleim J.A., Lussnig E., Schwarz E.R., Comery T.A., Greenough W.T. Synaptogenesis and Fos expression in the motor cortex of the adult rat after motor skill learning. J Neurosci 1996, 16(14):4529-4535.
    • (1996) J Neurosci , vol.16 , Issue.14 , pp. 4529-4535
    • Kleim, J.A.1    Lussnig, E.2    Schwarz, E.R.3    Comery, T.A.4    Greenough, W.T.5
  • 26
    • 0027408381 scopus 로고
    • Synapsin I, synapsin II, and synaptophysin: marker proteins of synaptic vesicles
    • Thiel G. Synapsin I, synapsin II, and synaptophysin: marker proteins of synaptic vesicles. Brain Pathol 1993, 3(1):87-95.
    • (1993) Brain Pathol , vol.3 , Issue.1 , pp. 87-95
    • Thiel, G.1
  • 27
    • 0022512022 scopus 로고
    • Expression of synaptophysin during postnatal development of the mouse brain
    • Knaus P., Betz H., Rehm H. Expression of synaptophysin during postnatal development of the mouse brain. J Neurochem 1986, 47(4):1302-1304.
    • (1986) J Neurochem , vol.47 , Issue.4 , pp. 1302-1304
    • Knaus, P.1    Betz, H.2    Rehm, H.3
  • 28
    • 0021178771 scopus 로고
    • Towards an improved serum-free, chemically defined medium for long-term culturing of cerebral cortex tissue
    • Romijn H.J., van Huizen F., Wolters P.S. Towards an improved serum-free, chemically defined medium for long-term culturing of cerebral cortex tissue. Neurosci Biobehav Rev 1984, 8:301-304.
    • (1984) Neurosci Biobehav Rev , vol.8 , pp. 301-304
    • Romijn, H.J.1    van Huizen, F.2    Wolters, P.S.3
  • 29
    • 0019639322 scopus 로고
    • Nerve outgrowth, synaptogenesis and bioelectric activity in fetal rat cerebral cortex tissue cultured in serum-free, chemically defined medium
    • Romijn H.J., Habets M., Mud M.T., Wolters P.S. Nerve outgrowth, synaptogenesis and bioelectric activity in fetal rat cerebral cortex tissue cultured in serum-free, chemically defined medium. Dev Brain Res 1981, 2:583-589.
    • (1981) Dev Brain Res , vol.2 , pp. 583-589
    • Romijn, H.J.1    Habets, M.2    Mud, M.T.3    Wolters, P.S.4
  • 30
    • 33846435771 scopus 로고    scopus 로고
    • Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic beta-cells and human islets: involvement of 3',5'-cyclic adenosine monophosphate/protein kinase A, extracellular signal-regulated kinase 1/2, and phosphatidyl inositol 3-Kinase/Akt signaling
    • Granata R., Settanni F., Biancone L., Trovato L., Nano R., Bertuzzi F., Destefanis S., Annunziata M., Martinetti M., Catapano F., Ghè C., Isgaard J., Papotti M., Ghigo E., Muccioli G. Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic beta-cells and human islets: involvement of 3',5'-cyclic adenosine monophosphate/protein kinase A, extracellular signal-regulated kinase 1/2, and phosphatidyl inositol 3-Kinase/Akt signaling. Endocrinology 2007, 148(2):512-529.
    • (2007) Endocrinology , vol.148 , Issue.2 , pp. 512-529
    • Granata, R.1    Settanni, F.2    Biancone, L.3    Trovato, L.4    Nano, R.5    Bertuzzi, F.6    Destefanis, S.7    Annunziata, M.8    Martinetti, M.9    Catapano, F.10    Ghè, C.11    Isgaard, J.12    Papotti, M.13    Ghigo, E.14    Muccioli, G.15
  • 32
    • 0019423594 scopus 로고
    • Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures
    • Hsu S.M., Raine L., Fanger H. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 1981, 29:577-580.
    • (1981) J Histochem Cytochem , vol.29 , pp. 577-580
    • Hsu, S.M.1    Raine, L.2    Fanger, H.3
  • 33
    • 0018070087 scopus 로고
    • Distribution of substance P-like immunoreactivity in the central nervous system of the rat-I. Cell bodies and nerve terminals
    • Ljungdahl A., Hökfelt T., Nilsson G. Distribution of substance P-like immunoreactivity in the central nervous system of the rat-I. Cell bodies and nerve terminals. Neuroscience 1978, 3(10):861-943.
    • (1978) Neuroscience , vol.3 , Issue.10 , pp. 861-943
    • Ljungdahl, A.1    Hökfelt, T.2    Nilsson, G.3
  • 34
    • 18244380554 scopus 로고    scopus 로고
    • Activation of early silent synapses by spontaneous synchronous network activity limits the range of network connections
    • Voigt T., Opitz T., de Lima A.D. Activation of early silent synapses by spontaneous synchronous network activity limits the range of network connections. J Neurosci 2005, 25:4605-4615.
    • (2005) J Neurosci , vol.25 , pp. 4605-4615
    • Voigt, T.1    Opitz, T.2    de Lima, A.D.3
  • 35
    • 33745454023 scopus 로고    scopus 로고
    • Dissociated cortical networks show spontaneously correlated activity patterns during in vitro development
    • Chiappalone M., Bove M., Vato A., Tedesco M., Martinoia S. Dissociated cortical networks show spontaneously correlated activity patterns during in vitro development. Brain Res 2006, 1093:41-53.
    • (2006) Brain Res , vol.1093 , pp. 41-53
    • Chiappalone, M.1    Bove, M.2    Vato, A.3    Tedesco, M.4    Martinoia, S.5
  • 36
    • 34247240602 scopus 로고    scopus 로고
    • Conditional firing probabilities in cultured neuronal networks: a stable underlying structure in widely varying spontaneous activity patterns
    • le Feber J., Rutten W.L.C., Stegenga J., Wolters P.S., Ramakers G.J., van Pelt J. Conditional firing probabilities in cultured neuronal networks: a stable underlying structure in widely varying spontaneous activity patterns. J Neural Eng 2007, 4:54-67.
    • (2007) J Neural Eng , vol.4 , pp. 54-67
    • le Feber, J.1    Rutten, W.L.C.2    Stegenga, J.3    Wolters, P.S.4    Ramakers, G.J.5    van Pelt, J.6
  • 38
    • 74749086909 scopus 로고    scopus 로고
    • Activity-dependent modulation of neural circuit synaptic connectivity
    • Tessier C.R., Broadie K. Activity-dependent modulation of neural circuit synaptic connectivity. Front Mol Neurosci 2009, 2(art8):1-13.
    • (2009) Front Mol Neurosci , vol.2 , Issue.8 ART , pp. 1-13
    • Tessier, C.R.1    Broadie, K.2
  • 39
    • 0027481101 scopus 로고
    • Formation and maturation of synapses in primary cultures of rat cerebral cortical cells: an electron microscopic study
    • Ichikawa M., Muramoto K., Kobayashi K., Kawahara M., Kuroda Y. Formation and maturation of synapses in primary cultures of rat cerebral cortical cells: an electron microscopic study. Neurosci Res 1993, 16:95-103.
    • (1993) Neurosci Res , vol.16 , pp. 95-103
    • Ichikawa, M.1    Muramoto, K.2    Kobayashi, K.3    Kawahara, M.4    Kuroda, Y.5
  • 40
    • 30344456451 scopus 로고    scopus 로고
    • How to build a central synapse: clues from cell culture
    • Craig A.M., Graf E.R., Linhoff M.W. How to build a central synapse: clues from cell culture. Trends Neurosci 2006, 29(1):8-20.
    • (2006) Trends Neurosci , vol.29 , Issue.1 , pp. 8-20
    • Craig, A.M.1    Graf, E.R.2    Linhoff, M.W.3
  • 41
    • 84879957985 scopus 로고    scopus 로고
    • Building a synapse: a complex matter
    • Kim Y.J., Serpe M. Building a synapse: a complex matter. Fly (Austin) 2013, 7(3):1-7.
    • (2013) Fly (Austin) , vol.7 , Issue.3 , pp. 1-7
    • Kim, Y.J.1    Serpe, M.2
  • 46
    • 33845910446 scopus 로고    scopus 로고
    • Ghrelin inhibits apoptosis in hypothalamic neuronal cells during oxygen-glucose deprivation
    • Chung H., Kim E., Lee D.H., Seo S., Ju S., Lee D., Kim H., Park S. Ghrelin inhibits apoptosis in hypothalamic neuronal cells during oxygen-glucose deprivation. Endocrinology 2007, 148(1):148-159.
    • (2007) Endocrinology , vol.148 , Issue.1 , pp. 148-159
    • Chung, H.1    Kim, E.2    Lee, D.H.3    Seo, S.4    Ju, S.5    Lee, D.6    Kim, H.7    Park, S.8
  • 49
    • 15744363782 scopus 로고    scopus 로고
    • Synaptogenesis: a balancing act between excitation and inhibition
    • Cline H. Synaptogenesis: a balancing act between excitation and inhibition. Curr Biol 2005, 15(6):R203-R205.
    • (2005) Curr Biol , vol.15 , Issue.6
    • Cline, H.1
  • 50
    • 0742322856 scopus 로고    scopus 로고
    • Postsynaptic density 95 controls AMPA receptor incorporation during long-term potentiation and experience-driven synaptic plasticity
    • Ehrlich I., Malinow R. Postsynaptic density 95 controls AMPA receptor incorporation during long-term potentiation and experience-driven synaptic plasticity. J Neurosci 2004, 24(4):916-927.
    • (2004) J Neurosci , vol.24 , Issue.4 , pp. 916-927
    • Ehrlich, I.1    Malinow, R.2
  • 51
    • 0027448053 scopus 로고
    • Agrin and the molecular choreography of synapse formation
    • Nastuk M.A., Fallon J.R. Agrin and the molecular choreography of synapse formation. Trends Neurosci 1993, 16(2):72-76.
    • (1993) Trends Neurosci , vol.16 , Issue.2 , pp. 72-76
    • Nastuk, M.A.1    Fallon, J.R.2
  • 52
    • 18844396417 scopus 로고    scopus 로고
    • Agrin mediates a rapid switch from electrical coupling to chemical neurotransmission during synaptogenesis
    • Martin A.O., Alonso G., Guérineau N.C. Agrin mediates a rapid switch from electrical coupling to chemical neurotransmission during synaptogenesis. J Cell Biol 2005, 169(3):503-514.
    • (2005) J Cell Biol , vol.169 , Issue.3 , pp. 503-514
    • Martin, A.O.1    Alonso, G.2    Guérineau, N.C.3
  • 53
    • 0027527614 scopus 로고
    • Activity-dependent development of the neuromuscular synapse during Drosophila embryogenesis
    • Broadie K., Bate M. Activity-dependent development of the neuromuscular synapse during Drosophila embryogenesis. Neuron 1993, 11(4):607-619.
    • (1993) Neuron , vol.11 , Issue.4 , pp. 607-619
    • Broadie, K.1    Bate, M.2
  • 54
    • 21844476512 scopus 로고    scopus 로고
    • Synapse composition and organization following chronic activity blockade in cultured hippocampal neurons
    • Harms K.J., Craig A.M. Synapse composition and organization following chronic activity blockade in cultured hippocampal neurons. J Comp Neurol 2005, 490(1):72-84.
    • (2005) J Comp Neurol , vol.490 , Issue.1 , pp. 72-84
    • Harms, K.J.1    Craig, A.M.2
  • 55
    • 0018228773 scopus 로고
    • Spontaneous motor rhythms in early life - phenomenological and physiological aspects
    • Corner M.A. Spontaneous motor rhythms in early life - phenomenological and physiological aspects. Prog Brain Res 1978, 48:349-364.
    • (1978) Prog Brain Res , vol.48 , pp. 349-364
    • Corner, M.A.1
  • 56
    • 79955467659 scopus 로고    scopus 로고
    • Neuronal activity is required for the development of specific cortical interneuron subtypes
    • De Marco García N.V., Karayannis T., Fishell G. Neuronal activity is required for the development of specific cortical interneuron subtypes. Nature 2011, 472(7343):351-355.
    • (2011) Nature , vol.472 , Issue.7343 , pp. 351-355
    • De Marco García, N.V.1    Karayannis, T.2    Fishell, G.3
  • 57
    • 67649410703 scopus 로고    scopus 로고
    • Latency related development of functional connections in cultured cortical networks
    • le Feber J., Van Pelt J., Rutten W. Latency related development of functional connections in cultured cortical networks. Biophys J 2009, 96:3443-3450.
    • (2009) Biophys J , vol.96 , pp. 3443-3450
    • le Feber, J.1    Van Pelt, J.2    Rutten, W.3


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