Registration-based assessment of regional lung function via volumetric CT images of normal subjects vs. severe asthmatics

Journal of Applied Physiology

Volumn 115, Issue 5, 2013, Pages 730-742

  Choi, Sanghun ^a,b   Hoffman, Eric A ^a,c   Wenzel, Sally E ^d   Tawhai, Merryn H ^e   Yin, Youbing ^a   Castro, Mario ^f   Lin, Ching Long ^a,b  

^a IA United States   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF AUCKLAND   (New Zealand)

^f WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Air trapping; Asthma; Image registration; Lung mechanics; Quantitative computed tomography

Indexed keywords

ADULT; AIR TRAPPING; ARTICLE; ASTHMA; COMPUTER ASSISTED TOMOGRAPHY; CONE BEAM COMPUTED TOMOGRAPHY; FEMALE; FORCED EXPIRATORY VOLUME; FUNCTIONAL RESIDUAL CAPACITY; HUMAN; IMAGE REGISTRATION; LUNG; LUNG FUNCTION TEST; LUNG MECHANICS; MALE; METHODOLOGY; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; QUANTITATIVE COMPUTED TOMOGRAPHY; RADIOGRAPHY; TIDAL VOLUME;

AIR TRAPPING; ASTHMA; IMAGE REGISTRATION; LUNG MECHANICS; QUANTITATIVE COMPUTED TOMOGRAPHY;

ADULT; ASTHMA; CONE-BEAM COMPUTED TOMOGRAPHY; FEMALE; FORCED EXPIRATORY VOLUME; FUNCTIONAL RESIDUAL CAPACITY; HUMANS; LUNG; MALE; MIDDLE AGED; RESPIRATORY FUNCTION TESTS; TIDAL VOLUME; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84883572455     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00113.2013     Document Type: Article

References (61)

1. Altes TA, Powers PL, Knight-Scott J, Rakes G, Platts-Mills TA, de Lange EE, Alford BA, Mugler JP, Brookeman JR. Hyperpolarized 3He MR lung ventilation imaging in asthmatics: preliminary findings. J Magn Reson Imaging 13: 378-384, 2001.
2. Amelon R, Cao K, Ding K, Christensen GE, Reinhardt JM, Raghavan ML. Three-dimensional characterization of regional lung deformation. J Biomech 44: 2489-2495, 2011.
3. Amis TC, Jones HA, Hughes JM. Effect of posture on inter-regional distribution of pulmonary ventilation in man. Respir Physiol 56: 145-167, 1984.
4. Bake B, Bjure J, Grimby G, Milic-Emili J, Nilsson NJ. Regional distribution of inspired gas in supine man. Scand J Respir Dis 48: 189-196, 1967.
5. Brown MS, Kim HJ, Abtin F, Da Costa I, Pais R, Ahmad S, Angel E, Ni C, Kleerup EC, Gjertson DW. Reproducibility of lung and lobar volume measurements using computed tomography. Acad Radiol 17: 316-322, 2010.
6. Brown MS, McNitt-Gray MF, Goldin JG, Greaser LE, Hayward UM, Sayre JW, Arid MK, Aberle DR. Automated measurement of single and total lung volume from CT. J Comput Assist Tomogr 23: 632-640, 1999.
7. Busacker A, Newell JD Jr, Keefe T, Hoffman EA, Granroth JC, Castro M, Fain S, Wenzel S. A multivariate analysis of risk factors for the air-trapping asthmatic phenotype as measured by quantitative CT analysis. Chest 135: 48-56, 2009.
8. Busse WW, Lemanske RF Jr. Asthma. N Engl J Med 344: 350-362, 2001.
9. Campana L, Kenyon J, Zhalehdoust-Sani S, Tzeng YS, Sun Y, Albert M, Lutchen KR. Probing airway conditions governing ventilation defects in asthma via hyperpolarized MRI image functional modeling. J Appl Physiol 106: 1293-1300, 2009.
10. Castillo R, Castillo E, Guerra R, Johnson VE, McPhail T, Garg AK, Guerrero T. A framework for evaluation of deformable image registration spatial accuracy using large landmark point sets. Phys Med Biol 54: 1849-1870, 2009.
11. Castillo R, Castillo E, Martinez J, Guerrero T. Ventilation from four-dimensional computed tomography: density versus Jacobian methods. Phys Med Biol 55: 4661-4685, 2010.
12. Castro M, Fain SB, Hoffman EA, Gierada DS, Erzurum SC, Wenzel S; National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Lung imaging in asthmatic patients: the picture is clearer. J Allergy Clin Immunol 128: 467-478, 2011.
13. Choi Y, Lee S. Injectivity conditions of 2D and 3D uniform cubic B-spline functions. Graphical Models 62: 411-427, 2000.
14. Clausen J. Measurement of absolute lung volumes by imaging techniques. Eur Respir J 10: 2427-2431, 1997.
15. Coxson H, Mayo J, Behzad H, Moore B, Verburgt L, Staples C, Pare P, Hogg J. Measurement of lung expansion with computed tomography and comparison with quantitative histology. J Appl Physiol 79: 1525- 1530, 1995.
16. de Lange EE, Altes TA, Patrie JT, Battiston JJ, Juersivich AP, Mugler JP 3rd, Platts-Mills TA. Changes in regional airflow obstruction over time in the lungs of patients with asthma: evaluation with 3He MR imaging. Radiology 250: 567-575, 2009.
17. de Lange EE, Altes TA, Patrie JT, Parmar J, Brookeman JR, Mugler JP 3rd, Platts-Mills TA. The variability of regional airflow obstruction within the lungs of patients with asthma: assessment with hyperpolarized helium-3 magnetic resonance imaging. J Allergy Clin Immunol 119: 1072-1078, 2007.
18. Ding K, Yin Y, Cao K, Christensen GE, Lin CL, Hoffman EA, Reinhardt JM. Evaluation of lobar biomechanics during respiration using image registration. Med Image Comput Comput Assist Interv 5761: 739- 746, 2009.
19. Engel LA, Prefaut C. Cranio-caudal distribution of inspired gas and perfusion in supine man. Respir Physiol 45: 43-53, 1981.
20. Fain SB, Peterson ET, Sorkness RL, Wenzel S, Castro M, Busse WW. Severe asthma research program-phenotyping and quantification of severe asthma. Imaging Decisions MRI 13: 24-27, 2009.
21. Froese AB, Bryan AC. Effects of anesthesia and paralysis on diaphragmatic mechanics in man. Anesthesiology 41: 242-255, 1974.
22. Fuld MK, Easley RB, Saba OI, Chon D, Reinhardt JM, Hoffman EA, Simon BA. CT-measured regional specific volume change reflects regional ventilation in supine sheep. J Appl Physiol 104: 1177-1184, 2008.
23. Galbán CJ, Han MK, Boes JL, Chughtai KA, Meyer CR, Johnson TD, Galbán S, Rehemtulla A, Kazerooni EA, Martinez FJ, Ross BD. Computed tomography-based biomarker provides unique signature for diagnosis of COPD phenotypes and disease progression. Nat Med 18: 1711-1715, 2012.
24. Gevenois PA, De Vuyst P, De Maertelaer V, Zanen J, Jacobovitz D, Cosio MG, Yernault J. Comparison of computed density and microscopic morphometry in pulmonary emphysema. Am J Respir Crit Care Med 154: 187-192, 1996.
25. Halaweish AF, Hoffman EA, Thedens DR, Fuld MK, Sieren JP, van Beek EJ. Effect of Lung Inflation Level on Hyperpolarized 3He Apparent Diffusion Coefficient Measurements in Never-Smokers. Radiology. Published online before print April 16, 2013, doi: 1148/radiol.13120005
26. Hankinson JL, Odencrantz JR, Fedan KB. Spirometric reference values from a sample of the general US population. Am J Respir Crit Care Med 159: 179-187, 1999.
27. Harris RS, Fujii-Rios H, Winkler T, Musch G, Vidal Melo MF, Venegas JG. Ventilation defect formation in healthy and asthma subjects is determined by lung inflation. PLoS One 7: e53216, 2012.
28. Harris RS, Winkler T, Musch G, Vidal Melo MF, Schroeder T, Tgavalekos N, Venegas JG. The prone position results in smaller ventilation defects during bronchoconstriction in asthma. J Appl Physiol 107: 266-274, 2009.
29. Harris RS, Winkler T, Tgavalekos N, Musch G, Melo MF, Schroeder T, Chang Y, Venegas JG. Regional pulmonary perfusion, inflation, and ventilation defects in bronchoconstricted patients with asthma. Am J Respir Crit Care Med 174: 245-253, 2006.
30. Heckscher T, Bass H, Oriol A, Rose B, Anthoniesen NR, Bates DV. Regional lung function in patients with bronchial asthma. J Clin Invest 47: 1063-1070, 1968.
31. Hoffman EA. Effect of body orientation on regional lung expansion: a computed tomographic approach. J Appl Physiol 59: 468-480, 1985.
32. Hoffman EA, Ritman EL. Effect of body orientation on regional lung expansion in dog and sloth. J Appl Physiol 59: 481-491, 1985.
33. Hoffman EA, Simon BA, McLennan G. State of the Art. A structural and functional assessment of the lung via multidetector-row computed tomography: phenotyping chronic obstructive pulmonary disease. Proc Am Thorac Soc 3: 519-532, 2006.
34. Ibanez J, Raurich J. Normal values of functional residual capacity in the sitting and supine positions. Intensive Care Med 8: 173-177, 1982.
35. Jarjour NN, Erzurum SC, Bleecker ER, Calhoun WJ, Castro M, Comhair SA, Chung KF, Curran-Everett D, Dweik RA, Fain SB, Fitzpatrick AM, Gaston BM, Israel E, Hastie A, Hoffman EA, Holguin F, Levy BD, Meyers DA, Moore WC, Peters SP, Sorkness RL, Teague WG, Wenzel SE, Busse WW; NHLBI Severe Asthma Research Program (SARP). Severe asthma: lessons learned from the National Heart, Lung, and Blood Institute Severe Asthma Research Program. Am J Respir Crit Care Med 185: 356-362, 2012.
36. King GG, Harris B, Mahadev S. V/Q SPECT: utility for investigation of pulmonary physiology. Semin Nucl Med 40: 467-473, 2010.
37. Lawrence MA. ez: Easy Analysis and Visualization of Factorial Experiments. R package version 1-1, 2012. [The software is available at http://CRAN.R-project.org/package-ez]
38. Mase GT, Smelser R, Mase GE. Continuum Mechanics for Engineers (Series: Computational Mechanics and Applied Analysis). Boca Raton, FL: CRC, 2009.
39. Mathew L, Wheatley A, Castillo R, Castillo E, Rodrigues G, Guerrero T, Parraga G. Hyperpolarized (3)He magnetic resonance imaging: comparison with four-dimensional x-ray computed tomography imaging in lung cancer. Acad Radiol 19: 1546-1553, 2012.
40. Moore WC, Bleecker ER, Curran-Everett D, Erzurum SC, Ameredes BT, Bacharier L, Calhoun WJ, Castro M, Chung KF, Clark MP, Dweik RA, Fitzpatrick AM, Gaston B, Hew M, Hussain I, Jarjour NN, Israel E, Levy BD, Murphy JR, Peters SP, Teague WG, Meyers DA, Busse WW, Wenzel SE; National Heart, Lung, Blood Institute's Severe Asthma Research Program. Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. J Allergy Clin Immunol 119: 405-413, 2007.
41. Moore WC, Meyers DA, Wenzel SE, Teague WG, Li H, Li X, D'Agostino R Jr, Castro M, Curran-Everett D, Fitzpatrick AM, Gaston B, Jarjour NN, Sorkness R, Calhoun WJ, Chung KF, Comhair SA, Dweik RA, Israel E, Peters SP, Busse WW, Erzurum SC, Bleecker ER; National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med 181: 315-323, 2010.
42. Moreno F, Lyons HA. Effect of body posture on lung volumes. J Appl Physiol 16: 27-29, 1961.
43. Musch G, Layfield JD, Harris RS, Melo MF, Winkler T, Callahan RJ, Fischman AJ, Venegas JG. Topographical distribution of pulmonary perfusion and ventilation, assessed by PET in supine and prone humans. J Appl Physiol 93: 1841-1851, 2002.
44. Newman KB, Lynch DA, Newman LS, Ellegood D, Newell JD Jr. Quantitative computed tomography detects air trapping due to asthma. Chest 106: 105-109, 1994.
45. Reinhardt JM, Ding K, Cao K, Christensen GE, Hoffman EA, Bodas SV. Registration-based estimates of local lung tissue expansion compared to xenon CT measures of specific ventilation. Med Image Anal 12: 752-763, 2008.
46. Robinson PJ, Kreel L. Pulmonary tissue attenuation with computed tomography: comparison of inspiration and expiration scans. J Comput Assist Tomogr 3: 740-748, 1979.
47. Sorkness RL, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Chung KF, Curran-Everett D, Erzurum SC, Gaston BM, Israel E, Jarjour NN, Moore WC, Peters SP, Teague WG, Wenzel SE; National Heart, Lung, and Blood Institute Severe Asthma Research Program. Lung function in adults with stable but severe asthma: air trapping and incomplete reversal of obstruction with bronchodilation. J Appl Physiol 104: 394-403, 2008.
48. Stocks J, Quanjer PH. Reference values for residual volume, functional residual capacity and total lung capacity. Eur Respir J 8: 492-506, 1995.
49. Tzeng YS, Hoffman E, Cook-Granroth J, Gereige J, Mansour J, Washko G, Cho M, Stepp E, Lutchen K, Albert M. Investigation of hyperpolarized 3He magnetic resonance imaging utility in examining human airway diameter behavior in asthma through comparison with high-resolution computed tomography. Acad Radiol 15: 799-808, 2008.
50. Venegas JG, Schroeder T, Harris S, Winkler RT, Melo MF. The distribution of ventilation during bronchoconstriction is patchy and bimodal: a PET imaging study. Respir Physiol Neurobiol 148: 57-64, 2005.
51. Venegas JG, Winkler T, Musch G, Vidal Melo MF, Layfield D, Tgavalekos N, Fischman AJ, Callahan RJ, Bellani G, Harris RS. Self-organized patchiness in asthma as a prelude to catastrophic shifts. Nature 434: 777-782, 2005.
52. Wanger J, Clausen J, Coates A, Pedersen O, Brusasco V, Burgos F, Casaburi R, Crapo R, Enright P, Van Der Grinten C. Standardisation of the measurement of lung volumes. Eur Respir J 26: 511-522, 2005.
53. Washko G, Parraga G, Coxson H. Quantitative pulmonary imaging using computed tomography and magnetic resonance imaging. Respirology 17: 432-444, 2012.
54. Wenzel SE, Busse WW; National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Severe asthma: lessons from the severe asthma research program. J Allergy Clin Immunol 119: 14-21, 2007.
55. West JB. Respiratory Physiology: the Essentials. Philadelphia, PA: Lippincott Williams & Wilkins, 2008.
56. Yin Y, Choi J, Hoffman EA, Tawhai MH, Lin CL. Simulation of pulmonary air flow with a subject-specific boundary condition. J Biomech 43: 2159-2163, 2010.
57. Yin Y, Hoffman EA, Lin CL. Local tissue-weight-based nonrigid registration of lung images with application to regional ventilation. Proc of SPIE 7262: 72620C, 2009.
58. Yin Y, Hoffman EA, Lin CL. Mass preserving nonrigid registration of CT lung images using cubic B-spline. Med Phys 36: 4213-4222, 2009.
59. Yin Y, Hoffman EA, Lin CL. Lung lobar slippage assessed with the aid of image registration. Med Image Comput Comput Assist Interv 6362: 578-585, 2010.
60. Yin Y, Choi J, Hoffman EA, Tawhai MH, Lin CL. A multiscale MDCT image-based breathing lung model with time-varying regional ventilation. J Comput Phys 244: 168-192, 2012.
61. Zapke M, Topf HG, Zenker M, Kuth R, Deimling M, Kreisler P, Rauh M, Chefd'hotel C, Geiger B, Rupprecht T. Magnetic resonance lung function-a breakthrough for lung imaging and functional assessment? A phantom study and clinical trial. Respir Res 6: 106, 2006.