Resistin disrupts glycogen synthesis under high insulin and high glucose levels by down-regulating the hepatic levels of GSK3β

Gene

Volumn 529, Issue 1, 2013, Pages 50-56

  Song, Rongjing ^a   Wang, Xi ^a   Mao, Yiqing ^a   Li, Hui ^a   Li, Zhixin ^a   Xu, Wei ^a   Wang, Rong ^a   Guo, Tingting ^a   Jin, Ling ^a   Zhang, Xiaojing ^a   Zhang, Yizhuang ^a   Zhou, Na ^a   Hu, Ruobi ^a   Jia, Jianwei ^b   Lei, Zhen ^b   Irwin, David M ^a,c   Niu, Gang ^d   Tan, Huanran ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b NINGXIA MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF TORONTO   (Canada)

^d Beijing N and N Genetech Company   (China)

Author keywords

Glycogen synthase kinase 3 (GSK 3 ); Insulin resistance; Liver; Resistin

Indexed keywords

GLUCOSE; GLYCOGEN; GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR BETA; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RESISTIN; SERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE OVEREXPRESSION; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLYCOGEN METABOLISM; GLYCOGEN SYNTHESIS; LIVER; LIVER CELL CULTURE; LIVER METABOLISM; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

AKT; GLYCOGEN SYNTHASE KINASE-3Β; GLYCOGEN SYNTHASE KINASE-3Β (GSK-3Β); GSK-3Β; INSULIN RECEPTOR Β; INSULIN RECEPTOR SUBSTRATE; INSULIN RESISTANCE; IRΒ; IRS; LIVER; PEPCK (ALSO CALLED PCK1); PHOSPHOENOLPYRUVATECARBOXYKINASE; PHOSPHOINOSITIDE 3-KINASE; PI3K; PROTEIN KINASE B; RESISTIN; SOCS; SUPPRESSORS OF CYTOKINE SIGNALING; TNFΑ; TUMOR NECROSIS FACTOR ALPHA;

ANIMALS; CELL LINE; DOWN-REGULATION; FASTING; GLYCOGEN SYNTHASE KINASE 3; HEPATOCYTES; HYPERINSULINISM; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; LIVER; LIVER GLYCOGEN; MALE; MICE; MICE, INBRED BALB C; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, INSULIN; RESISTIN; SIGNAL TRANSDUCTION;

MURINAE; MUS; RATTUS;

EID: 84883560722     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2013.06.085     Document Type: Article

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