-
1
-
-
84883560631
-
-
In silico prediction of physicochemical properties. EUR 23051 EN. Joint Research Centre, European Commission, Ispra, Italy.
-
Dearden J, Worth A. 2007. In silico prediction of physicochemical properties. EUR 23051 EN. Joint Research Centre, European Commission, Ispra, Italy.
-
(2007)
-
-
Dearden, J.1
Worth, A.2
-
2
-
-
84883558483
-
-
European Commission. Regulation (EC) 1907/2006 of the European Parliament and of the Council of 18 December 2006 concerning the registration, evaluation, authorisation and restriction of chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) 793/93 and Commission Regulation (EC) No. 1488/94 as well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC
-
European Commission. 2006. Regulation (EC) 1907/2006 of the European Parliament and of the Council of 18 December 2006 concerning the registration, evaluation, authorisation and restriction of chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) 793/93 and Commission Regulation (EC) No. 1488/94 as well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC. Official J Eur Union L396:374-375.
-
(2006)
Official J Eur Union
, vol.396 L
, pp. 374-375
-
-
-
3
-
-
84883558957
-
-
Organisation for Economic Co-operation and Development. Guidance document on the validation of (quantitative) structure-activity relationships ([Q]SAR) models. Series on Testing and Assessment, No. 69. ENV/JM/MONO(2007)2. Paris, France.
-
Organisation for Economic Co-operation and Development. 2007. Guidance document on the validation of (quantitative) structure-activity relationships ([Q]SAR) models. Series on Testing and Assessment, No. 69. ENV/JM/MONO(2007)2. Paris, France.
-
(2007)
-
-
-
4
-
-
0142089677
-
Overview of data and conceptual approaches for derivation of quantitative structure-activity relationships for ecotoxicological effects of organic chemicals
-
Bradbury SP, Russom CL, Ankley GT, Schultz TW, Walker JD. 2003. Overview of data and conceptual approaches for derivation of quantitative structure-activity relationships for ecotoxicological effects of organic chemicals. Environ Toxicol Chem 22:1789-1798.
-
(2003)
Environ Toxicol Chem
, vol.22
, pp. 1789-1798
-
-
Bradbury, S.P.1
Russom, C.L.2
Ankley, G.T.3
Schultz, T.W.4
Walker, J.D.5
-
5
-
-
0037501161
-
A generic QSAR for assessing the bioaccumulation potential of organic chemicals in aquatic food webs
-
Arnot JA, Gobas FAPC. 2003. A generic QSAR for assessing the bioaccumulation potential of organic chemicals in aquatic food webs. QSAR Comb Sci 22:337-345.
-
(2003)
QSAR Comb Sci
, vol.22
, pp. 337-345
-
-
Arnot, J.A.1
Gobas, F.A.P.C.2
-
6
-
-
84883555731
-
-
Validation of (quantitative) structure-activity relationships for toxicological endpoints of regulatory importance: (Q)SARs for acute toxicity to fish. Final report, Part A. Joint Research Centre, Brussels, Belgium
-
Brooke D, Crookes M. 2006. Validation of (quantitative) structure-activity relationships for toxicological endpoints of regulatory importance: (Q)SARs for acute toxicity to fish. Final report, Part A. Joint Research Centre, Brussels, Belgium
-
(2006)
-
-
Brooke, D.1
Crookes, M.2
-
7
-
-
84883554917
-
-
Comparative assessment of QSAR models for aquatic toxicity. Joint Research Centre Report EUR 21750 EN. European Chemicals Bureau, Ispra, Italy.
-
Pavan M, Worth AP, Netzeva TI. 2005. Comparative assessment of QSAR models for aquatic toxicity. Joint Research Centre Report EUR 21750 EN. European Chemicals Bureau, Ispra, Italy.
-
(2005)
-
-
Pavan, M.1
Worth, A.P.2
Netzeva, T.I.3
-
8
-
-
84883556338
-
-
Technical reference manual for the ECOSAR class program: Estimating toxicity of industrial chemicals to aquatic organisms using the ECOSAR class program. US Environmental Protection Agency, Washington, DC.
-
Mayo-Bean K, Moran K, Meylan B, Ranslow P. 2012. Technical reference manual for the ECOSAR class program: Estimating toxicity of industrial chemicals to aquatic organisms using the ECOSAR class program. US Environmental Protection Agency, Washington, DC.
-
(2012)
-
-
Mayo-Bean, K.1
Moran, K.2
Meylan, B.3
Ranslow, P.4
-
9
-
-
80051811373
-
Internal and external validation of the long-term QSARs for neutral organics to fish from ECOSAR
-
De Haas E, Eikelboom T, Bouwman T. 2011. Internal and external validation of the long-term QSARs for neutral organics to fish from ECOSAR. SAR QSAR Environ Res 22:545-559.
-
(2011)
SAR QSAR Environ Res
, vol.22
, pp. 545-559
-
-
De Haas, E.1
Eikelboom, T.2
Bouwman, T.3
-
10
-
-
0029585123
-
Atom/fragment contribution method for estimating octanol-water partition coefficients
-
Meylan WM, Howard P. 1995. Atom/fragment contribution method for estimating octanol-water partition coefficients. J Pharm Sci 84:83-92.
-
(1995)
J Pharm Sci
, vol.84
, pp. 83-92
-
-
Meylan, W.M.1
Howard, P.2
-
11
-
-
0141462446
-
(Q)SARs: Gatekeepers against risk on chemicals
-
Hulzebos E, Posthumus R. 2003. (Q)SARs: Gatekeepers against risk on chemicals? SAR QSAR Environ Res 14:285-316.
-
(2003)
SAR QSAR Environ Res
, vol.14
, pp. 285-316
-
-
Hulzebos, E.1
Posthumus, R.2
-
12
-
-
84883559830
-
-
European Chemicals Agency. Registered Substances. Helsinki (Finland). [cited: 2011 June 1]. Available from:
-
European Chemicals Agency. 2013. Registered Substances. Helsinki (Finland). [cited: 2011 June 1]. Available from: http://echa.europa.eu/web/guest/information-on-chemicals/registered-substances.
-
(2013)
-
-
-
13
-
-
84883557927
-
-
Oraganisation for Economic Co-operation and Development. QSAR toolbox,Ver 2.2: The OECD QSAR toolbox for grouping chemicals into categories. Paris (France). [cited: 2011 June 1]. Available from:
-
Oraganisation for Economic Co-operation and Development. 2011. QSAR toolbox, Ver 2.2: The OECD QSAR toolbox for grouping chemicals into categories. Paris (France). [cited: 2011 June 1]. Available from: http://www.qsartoolbox.org/.
-
(2011)
-
-
-
14
-
-
84883552997
-
-
National Institute of Technology and Evaluation. Chemical Risk Information Platform (CHIRP). Tokyo (Japan). [cited: 2011 June 1]. Available from:
-
National Institute of Technology and Evaluation. 2010. Chemical Risk Information Platform (CHIRP). Tokyo (Japan). [cited: 2011 June 1]. Available from: http://www.safe.nite.go.jp/english/db.html.
-
(2010)
-
-
-
15
-
-
84883552418
-
-
European Center for Ecotoxicology and Toxicology of Chemicals. European Centre for ecotoxicology and toxicology of chemicals. Brussels (Belgium). [cited: 2011 June 1]. Available from:
-
European Center for Ecotoxicology and Toxicology of Chemicals. 2010. European Centre for ecotoxicology and toxicology of chemicals. Brussels (Belgium). [cited: 2011 June 1]. Available from: http://www.ecetoc.org/.
-
(2010)
-
-
-
16
-
-
84883556511
-
-
Optimized Approach based on Structural Indices Set. Laboratory of Mathematical Chemistry. Bourges (Bulgaria). [cited: 2011 June 1]. Available from:
-
Optimized Approach based on Structural Indices Set. 2008. Laboratory of Mathematical Chemistry. Bourges (Bulgaria). [cited: 2011 June 1]. Available from: http://oasis-lmc.org/.
-
(2008)
-
-
-
17
-
-
84883557186
-
-
US Environmental Protection Agency. ECOTOX Database. Duluth (MN). [cited: 2011 June 1]. Available from:
-
US Environmental Protection Agency. 2011. ECOTOX Database. Duluth (MN). [cited: 2011 June 1]. Available from: http://cfpub.epa.gov/ecotox.
-
(2011)
-
-
-
18
-
-
0031080387
-
A systematic approach for evaluating the quality of experimental toxicological and ecotoxicological data
-
Klimisch HJ, Andreae M, Tillmann U. 1997. A systematic approach for evaluating the quality of experimental toxicological and ecotoxicological data. Regul Toxicol Pharmacol 25:1-5.
-
(1997)
Regul Toxicol Pharmacol
, vol.25
, pp. 1-5
-
-
Klimisch, H.J.1
Andreae, M.2
Tillmann, U.3
-
19
-
-
0026785215
-
Classifying environmental pollutants 1: Structure-activity relationships for prediction of aquatic toxicity
-
Verhaar HJM, van Leeuwen CJ, Hermens JLM. 1992. Classifying environmental pollutants 1: Structure-activity relationships for prediction of aquatic toxicity. Chemosphere 25:471-491.
-
(1992)
Chemosphere
, vol.25
, pp. 471-491
-
-
Verhaar, H.J.M.1
van Leeuwen, C.J.2
Hermens, J.L.M.3
-
20
-
-
84883551858
-
-
Toxtree. Toxic Hazard Estimation by decision tree approach. Ideaconsult. [cited: 2011 July 1]. Available from:
-
Toxtree. 2011. Toxic Hazard Estimation by decision tree approach. Ideaconsult. [cited: 2011 July 1]. Available from: http://toxtree.sourceforge.net/.
-
(2011)
-
-
-
21
-
-
50049090548
-
Classification of chemicals according to mechanism of aquatic toxicity: An evaluation of the implementation of the Verhaar scheme in Toxtree
-
Enoch SJ, Hewitt M, Cronin MTD, Azam S, Madden JC. 2008. Classification of chemicals according to mechanism of aquatic toxicity: An evaluation of the implementation of the Verhaar scheme in Toxtree. Chemosphere 73:243-248.
-
(2008)
Chemosphere
, vol.73
, pp. 243-248
-
-
Enoch, S.J.1
Hewitt, M.2
Cronin, M.T.D.3
Azam, S.4
Madden, J.C.5
-
22
-
-
84883554796
-
-
DRAGON software,Version 6.0: Molecular descriptors, QSAR, chemometrics and chemoinformatics. Milano (Italy). [cited: 2011 July 1]. Available from:
-
Talete srl. 2011. DRAGON software, Version 6.0: Molecular descriptors, QSAR, chemometrics and chemoinformatics. Milano (Italy). [cited: 2011 July 1]. Available from: http://www.talete.mi.it/products/dragon_description.htm.
-
(2011)
-
-
Talete, S.R.L.1
-
23
-
-
84883558128
-
-
ChemAxon. Structure database management, search & prediction. Budapest (Hungary). [cited: 2011 July 1]. Available from:
-
ChemAxon. 2011. Structure database management, search & prediction. Budapest (Hungary). [cited: 2011 July 1]. Available from: http://www.chemaxon.com/products/instant-jchem/.
-
(2011)
-
-
-
25
-
-
0002710759
-
Nonpolar narcosis: A review of the mechanism of action for baseline aquatic toxicity
-
In Cowgill UM, Williams LR, eds, ASTM STP 1027. American Society for Testing and Materials, Philadelphia, PA, USA
-
Schultz TW. 1984. Nonpolar narcosis: A review of the mechanism of action for baseline aquatic toxicity. In Cowgill UM, Williams LR, eds, Aquatic Toxicology and Hazard Assessment, Vol 12. ASTM STP 1027. American Society for Testing and Materials, Philadelphia, PA, USA, pp 104-109.
-
(1984)
Aquatic Toxicology and Hazard Assessment
, vol.12
, pp. 104-109
-
-
Schultz, T.W.1
-
26
-
-
0028357170
-
Toxicological assessment of biotransformation products of pentachlorophenol: Tetrahymena population growth impairment
-
Bryant SE, Schultz TW. 1994. Toxicological assessment of biotransformation products of pentachlorophenol: Tetrahymena population growth impairment. Arch Environ Contam Toxicol 26:299-303.
-
(1994)
Arch Environ Contam Toxicol
, vol.26
, pp. 299-303
-
-
Bryant, S.E.1
Schultz, T.W.2
-
27
-
-
0019777499
-
Influence of pH on the toxicity of substituted phenols to fish
-
Saarikoski J, Viluksela M. 1981. Influence of pH on the toxicity of substituted phenols to fish. Arch Environ Toxicol 10:747-753.
-
(1981)
Arch Environ Toxicol
, vol.10
, pp. 747-753
-
-
Saarikoski, J.1
Viluksela, M.2
-
28
-
-
0023426720
-
The use of ionization constant (pKa) in selecting models of toxicity in phenols
-
Schultz TW. 1984. The use of ionization constant (pKa) in selecting models of toxicity in phenols. Ecotoxicol Environ Saf 14:178-183.
-
(1984)
Ecotoxicol Environ Saf
, vol.14
, pp. 178-183
-
-
Schultz, T.W.1
-
29
-
-
0028474223
-
Relation between the chemical structures of chlorophenols and their dissociation constants and partition coefficients in several solvent-water systems
-
Kishino T, Kobayashi K. 1994. Relation between the chemical structures of chlorophenols and their dissociation constants and partition coefficients in several solvent-water systems. Water Res 28:1547-1552.
-
(1994)
Water Res
, vol.28
, pp. 1547-1552
-
-
Kishino, T.1
Kobayashi, K.2
-
30
-
-
0019476112
-
Quantitative structure-activity relationships in fish toxicity studies. Part 2: The influence of pH on the QSAR of chlorophenols
-
Könemann H, Musch A. 1981. Quantitative structure-activity relationships in fish toxicity studies. Part 2: The influence of pH on the QSAR of chlorophenols. Toxicology 19:223-228.
-
(1981)
Toxicology
, vol.19
, pp. 223-228
-
-
Könemann, H.1
Musch, A.2
-
31
-
-
0002867651
-
Polar narcosis in aquatic organisms
-
In Cowgill UM, Williams LR, eds, ASTM STP 1027. American Society for Testing and Materials, Philadelphia, PA, USA
-
Bradbury SP, Carlson RW, Henry TR. 1989. Polar narcosis in aquatic organisms. In Cowgill UM, Williams LR, eds, Aquatic Toxicology and Hazard Assessment, Vol 12, ASTM STP 1027. American Society for Testing and Materials, Philadelphia, PA, USA, pp 59-73.
-
(1989)
Aquatic Toxicology and Hazard Assessment
, vol.12
, pp. 59-73
-
-
Bradbury, S.P.1
Carlson, R.W.2
Henry, T.R.3
-
32
-
-
84988267123
-
Quantitative structure-activity relationship of environmental pollutants
-
In Hutzinger O, ed, 2nd ed. Springer, Berlin
-
Hermens J. 1989. Quantitative structure-activity relationship of environmental pollutants. In Hutzinger O, ed, Handbook of Environmental Chemistry, 2nd ed. Springer, Berlin, pp 111-162.
-
(1989)
Handbook of Environmental Chemistry
, pp. 111-162
-
-
Hermens, J.1
-
33
-
-
0029760713
-
Uptake, speciation and uncoupling activity of substituted phenols in energy transducing membranes
-
Escher BI, Snozzi M, Schwarzenbach RP. 1996. Uptake, speciation and uncoupling activity of substituted phenols in energy transducing membranes. Environ Sci Technol 30:3071-3079.
-
(1996)
Environ Sci Technol
, vol.30
, pp. 3071-3079
-
-
Escher, B.I.1
Snozzi, M.2
Schwarzenbach, R.P.3
-
34
-
-
84883557190
-
-
US Environmental Protection Agency. Ecological structure activity relationships (ECOSAR). Washington (DC). [cited: 2011 September 1]. Available from:
-
US Environmental Protection Agency. 2011. Ecological structure activity relationships (ECOSAR). Washington (DC). [cited: 2011 September 1]. Available from: http://www.epa.gov/oppt/newchems/tools/21ecosar.htm.
-
(2011)
-
-
-
35
-
-
84883553733
-
-
Bajot and Cronin. (Q)SAR Model Reporting Format Inventory. Brussels (Belgium): European Commission Joint Research Centre and the Institute for Health and Consumer Protection. [cited: 2012 May 1]. Available from:
-
Bajot and Cronin. 2009. (Q)SAR Model Reporting Format Inventory. Brussels (Belgium): European Commission Joint Research Centre and the Institute for Health and Consumer Protection. [cited: 2012 May 1]. Available from: http://qsardb.jrc.it/qmrf/search_catalogs.jsp?id=318&idstructure=
-
(2009)
-
-
-
36
-
-
38249042843
-
Relation of survival to other endpoints in chronic toxicity tests with fish
-
Mayer FL, Mayer KS, Ellersieck MR. 1986. Relation of survival to other endpoints in chronic toxicity tests with fish. Environ Toxicol Chem 5:737-748.
-
(1986)
Environ Toxicol Chem
, vol.5
, pp. 737-748
-
-
Mayer, F.L.1
Mayer, K.S.2
Ellersieck, M.R.3
-
37
-
-
2442467726
-
Culturing and toxicity testing with the New Zealand mysid Tenagomysis novae-zealandiae, with a summary of toxicological research in this group
-
Nipper MG, Williams EK. 1997. Culturing and toxicity testing with the New Zealand mysid Tenagomysis novae-zealandiae, with a summary of toxicological research in this group. Australas J Ecotoxicol 3:117-129.
-
(1997)
Australas J Ecotoxicol
, vol.3
, pp. 117-129
-
-
Nipper, M.G.1
Williams, E.K.2
-
38
-
-
0034000175
-
Ratios between acute aquatic toxicity and effects on population growth rates in relation to toxicant mode of action
-
Roex EWM, Van Gestel CAM, Van Wezel AP, Van Straalen NM. 2000. Ratios between acute aquatic toxicity and effects on population growth rates in relation to toxicant mode of action. Environ Toxicol Chem 19:685-693.
-
(2000)
Environ Toxicol Chem
, vol.19
, pp. 685-693
-
-
Roex, E.W.M.1
Van Gestel, C.A.M.2
Van Wezel, A.P.3
Van Straalen, N.M.4
-
39
-
-
0002805087
-
Complete life cycle tests with zebrafish-A critical assessment of the results
-
In Müller R, Lloyd R, eds, Blackwell, Oxford, UK
-
Nagel R. 1994. Complete life cycle tests with zebrafish-A critical assessment of the results. In Müller R, Lloyd R, eds, Sublethal and Chronic Effects of Pollutants on Freshwater Fish. Blackwell, Oxford, UK, pp 188-195.
-
(1994)
Sublethal and Chronic Effects of Pollutants on Freshwater Fish
, pp. 188-195
-
-
Nagel, R.1
-
40
-
-
0041816201
-
Prediction of ecological no-effect concentrations for initial risk assessment: Combining substance-specific data and database information
-
Roelofs W, Huijbregts MAJ, Jager T, Ragas AMJ. 2003. Prediction of ecological no-effect concentrations for initial risk assessment: Combining substance-specific data and database information. Environ Toxicol Chem 22:1387-1393.
-
(2003)
Environ Toxicol Chem
, vol.22
, pp. 1387-1393
-
-
Roelofs, W.1
Huijbregts, M.A.J.2
Jager, T.3
Ragas, A.M.J.4
-
41
-
-
84858619824
-
Discrepancies in the acute versus chronic toxicity of compounds with a designated narcotic mechanism
-
Dom N, Penninck M, Knapen D, Blust R. 2012. Discrepancies in the acute versus chronic toxicity of compounds with a designated narcotic mechanism. Chemosphere 87:742-749.
-
(2012)
Chemosphere
, vol.87
, pp. 742-749
-
-
Dom, N.1
Penninck, M.2
Knapen, D.3
Blust, R.4
-
43
-
-
78650200810
-
Consensus QSAR related to global or MOA models: Application to acute toxicity for fish
-
Lozano S, Halm-Lemeille MP, Lepailleur A, Rault S, Bureau R. 2010. Consensus QSAR related to global or MOA models: Application to acute toxicity for fish. Molecular Informatics 29:803-813.
-
(2010)
Molecular Informatics
, vol.29
, pp. 803-813
-
-
Lozano, S.1
Halm-Lemeille, M.P.2
Lepailleur, A.3
Rault, S.4
Bureau, R.5
-
44
-
-
0030981036
-
Predicting modes of toxic action from chemical structure: Acute toxicity in the fathead minnow (Pimephales promelas)
-
Russom CL, Bradbury SP, Broderius SJ, Hammermeister DE, Drummond RA. 1997. Predicting modes of toxic action from chemical structure: Acute toxicity in the fathead minnow (Pimephales promelas). Environ Toxicol Chem 16:948-967.
-
(1997)
Environ Toxicol Chem
, vol.16
, pp. 948-967
-
-
Russom, C.L.1
Bradbury, S.P.2
Broderius, S.J.3
Hammermeister, D.E.4
Drummond, R.A.5
-
45
-
-
0032241431
-
Comparison of Tetrahymena and Pimephales toxicity based on mechanism of action
-
Bearden AP, Schultz TW. 1998. Comparison of Tetrahymena and Pimephales toxicity based on mechanism of action. SAR QSAR Environ Res 9:127-153.
-
(1998)
SAR QSAR Environ Res
, vol.9
, pp. 127-153
-
-
Bearden, A.P.1
Schultz, T.W.2
-
46
-
-
84883555649
-
-
Q)SAR Model Reporting Format Inventory. Brussels (Belgium): European Commission Joint Research Centre and the Institute for Health and Consumer Protection. [cited: 2012 May 1]. Available from:
-
Pavan M. 2009. (Q)SAR Model Reporting Format Inventory. Brussels (Belgium): European Commission Joint Research Centre and the Institute for Health and Consumer Protection. [cited: 2012 May 1]. Available from: http://qsardb.jrc.it/qmrf/search_catalogs.jsp?id=162&idstructure=
-
(2009)
-
-
Pavan, M.1
|