-
1
-
-
0035811050
-
Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments
-
Alonso, A., Zaidi, T., Novak, M., Grundke-Iqbal, I., and Iqbal, K. (2001). Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments. Proc. Natl. Acad. Sci. U.S.A. 98, 6923
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 6923
-
-
Alonso, A.1
Zaidi, T.2
Novak, M.3
Grundke-Iqbal, I.4
Iqbal, K.5
-
2
-
-
20044367108
-
Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms
-
doi:10.1523/JNEUROSCI.4637-04.2005
-
Andorfer, C., Acker, C. M., Kress, Y., Hof, P. R., Duff, K., and Davies, P. (2005). Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms. J. Neurosci. 25, 5446-5454. doi:10.1523/JNEUROSCI.4637-04.2005
-
(2005)
J. Neurosci.
, vol.25
, pp. 5446-5454
-
-
Andorfer, C.1
Acker, C.M.2
Kress, Y.3
Hof, P.R.4
Duff, K.5
Davies, P.6
-
3
-
-
0029078383
-
Relative exon affinities and suboptimal splice site signals lead to non-equivalence of two cassette exons
-
doi:10.1093/nar/23.17.3585
-
Andreadis, A., Broderick, J. A., and Kosik, K. S. (1995). Relative exon affinities and suboptimal splice site signals lead to non-equivalence of two cassette exons. Nucleic Acids Res. 23, 3585-3593. doi:10.1093/nar/23.17.3585
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 3585-3593
-
-
Andreadis, A.1
Broderick, J.A.2
Kosik, K.S.3
-
4
-
-
17544393297
-
Tau dephosphorylation at tau-1 site correlates with its association to cell membrane
-
doi:10.1023/A:1007583214722
-
Arrasate, M., Perez, M., and Avila, J. (2000). Tau dephosphorylation at tau-1 site correlates with its association to cell membrane. Neurochem. Res. 25, 43-50. doi:10.1023/A:1007583214722
-
(2000)
Neurochem. Res.
, vol.25
, pp. 43-50
-
-
Arrasate, M.1
Perez, M.2
Avila, J.3
-
5
-
-
78149391828
-
Alzheimer disease: caspases first
-
doi:10.1038/nrneurol.2010.157
-
Avila, J. (2010). Alzheimer disease: caspases first. Nat Rev Neurol 6, 587-588. doi:10.1038/nrneurol.2010.157
-
(2010)
Nat Rev Neurol
, vol.6
, pp. 587-588
-
-
Avila, J.1
-
6
-
-
1642289188
-
Role of tau protein in both physiological and pathological conditions
-
doi:10.1152/physrev.00024.2003
-
Avila, J., Lucas, J. J., Perez, M., and Hernandez, F. (2004). Role of tau protein in both physiological and pathological conditions. Physiol. Rev. 84, 361-384. doi:10.1152/physrev.00024.2003
-
(2004)
Physiol. Rev.
, vol.84
, pp. 361-384
-
-
Avila, J.1
Lucas, J.J.2
Perez, M.3
Hernandez, F.4
-
7
-
-
79955784678
-
Tau regulates the subcellular localization of calmodulin
-
doi:10.1016/j.bbrc.2011.04.082
-
Barreda, E. G., and Avila, J. (2011). Tau regulates the subcellular localization of calmodulin. Biochem. Biophys. Res. Commun. 408, 500-504. doi:10.1016/j.bbrc.2011.04.082
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.408
, pp. 500-504
-
-
Barreda, E.G.1
Avila, J.2
-
8
-
-
77956504025
-
Tyrosine phosphorylation of tau accompanies disease progression in transgenic mouse models of tauopathy
-
doi:10.1111/j.1365-2990.2010.01103.x
-
Bhaskar, K., Hobbs, G. A., Yen, S. H., and Lee, G. (2010). Tyrosine phosphorylation of tau accompanies disease progression in transgenic mouse models of tauopathy. Neuropathol. Appl. Neurobiol. 36, 462-477. doi:10.1111/j.1365-2990.2010.01103.x
-
(2010)
Neuropathol. Appl. Neurobiol.
, vol.36
, pp. 462-477
-
-
Bhaskar, K.1
Hobbs, G.A.2
Yen, S.H.3
Lee, G.4
-
9
-
-
0024804051
-
Neurofibrillary degeneration and neuronal loss in Alzheimer's disease
-
doi:10.1016/0197-4580(89)90007-9
-
Bondareff, W., Mountjoy, C. Q., Roth, M., and Hauser, D. L. (1989). Neurofibrillary degeneration and neuronal loss in Alzheimer's disease. Neurobiol. Aging 10, 709-715. doi:10.1016/0197-4580(89)90007-9
-
(1989)
Neurobiol. Aging
, vol.10
, pp. 709-715
-
-
Bondareff, W.1
Mountjoy, C.Q.2
Roth, M.3
Hauser, D.L.4
-
10
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
doi:10.1007/BF00308809
-
Braak, H., and Braak, E. (1991). Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. 82, 239-259. doi:10.1007/BF00308809
-
(1991)
Acta Neuropathol.
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
11
-
-
10944241542
-
Tau alteration and neuronal degeneration in tauopathies: mechanisms and models
-
doi:10.1016/j.bbadis.2004.06.018
-
Brandt, R., Hundelt, M., and Shahani, N. (2005). Tau alteration and neuronal degeneration in tauopathies: mechanisms and models. Biochim. Biophys. Acta 1739, 331-354. doi:10.1016/j.bbadis.2004.06.018
-
(2005)
Biochim. Biophys. Acta
, vol.1739
, pp. 331-354
-
-
Brandt, R.1
Hundelt, M.2
Shahani, N.3
-
12
-
-
0028785525
-
Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain
-
doi:10.1083/jcb.131.5.1327
-
Brandt, R., Leger, J., and Lee, G. (1995). Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain. J. Cell Biol. 131, 1327-1340. doi:10.1083/jcb.131.5.1327
-
(1995)
J. Cell Biol.
, vol.131
, pp. 1327-1340
-
-
Brandt, R.1
Leger, J.2
Lee, G.3
-
13
-
-
49149098525
-
Tau aggregates: toxic, inert, or protective species? J
-
Bretteville, A., and Planel, E. (2008). Tau aggregates: toxic, inert, or protective species? J. Alzheimers Dis. 14, 431-436.
-
(2008)
Alzheimers Dis.
, vol.14
, pp. 431-436
-
-
Bretteville, A.1
Planel, E.2
-
14
-
-
0025098891
-
Inhibition of neurite polarity by tau antisense oligonucleotides in primary cerebellar neurons
-
doi:10.1038/343461a0
-
Caceres, A., and Kosik, K. S. (1990). Inhibition of neurite polarity by tau antisense oligonucleotides in primary cerebellar neurons. Nature 343, 461-463. doi:10.1038/343461a0
-
(1990)
Nature
, vol.343
, pp. 461-463
-
-
Caceres, A.1
Kosik, K.S.2
-
15
-
-
0033521983
-
DREAM is a Ca2+-regulated transcriptional repressor
-
doi:10.1038/18044
-
Carrion, A. M., Link, W. A., Ledo, F., Mellstrom, B., and Naranjo, J. R. (1999). DREAM is a Ca2+-regulated transcriptional repressor. Nature 398, 80-84. doi:10.1038/18044
-
(1999)
Nature
, vol.398
, pp. 80-84
-
-
Carrion, A.M.1
Link, W.A.2
Ledo, F.3
Mellstrom, B.4
Naranjo, J.R.5
-
16
-
-
67650077008
-
Transmission and spreading of tauopathy in transgenic mouse brain
-
doi:10.1038/ncb1901
-
Clavaguera, F., Bolmont, T., Crowther, R. A., Abramowski, D., Frank, S., Probst, A., et al. (2009). Transmission and spreading of tauopathy in transgenic mouse brain. Nat. Cell Biol. 11, 909-913. doi:10.1038/ncb1901
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 909-913
-
-
Clavaguera, F.1
Bolmont, T.2
Crowther, R.A.3
Abramowski, D.4
Frank, S.5
Probst, A.6
-
17
-
-
0019224686
-
Effects of DNA on microtubule assembly
-
doi:10.1111/j.1432-1033.1980.tb04468.x
-
Corces, V. G., Manso, R., De La Torre, J., Avila, J., Nasr, A., and Wiche, G. (1980). Effects of DNA on microtubule assembly. Eur. J. Biochem. 105, 7-16. doi:10.1111/j.1432-1033.1980.tb04468.x
-
(1980)
Eur. J. Biochem.
, vol.105
, pp. 7-16
-
-
Corces, V.G.1
Manso, R.2
De La Torre, J.3
Avila, J.4
Nasr, A.5
Wiche, G.6
-
18
-
-
0028918383
-
Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross-linking in Alzheimer disease
-
doi:10.1007/BF00309621
-
Cras, P., Smith, M. A., Richey, P. L., Siedlak, S. L., Mulvihill, P., and Perry, G. (1995). Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross-linking in Alzheimer disease. Acta Neuropathol. 89, 291-295. doi:10.1007/BF00309621
-
(1995)
Acta Neuropathol.
, vol.89
, pp. 291-295
-
-
Cras, P.1
Smith, M.A.2
Richey, P.L.3
Siedlak, S.L.4
Mulvihill, P.5
Perry, G.6
-
19
-
-
0011162190
-
Selective loss of central cholinergic neurons in Alzheimer's disease
-
doi:10.1016/S0140-6736(76)91936-X
-
Davies, P., and Maloney, A. J. (1976). Selective loss of central cholinergic neurons in Alzheimer's disease. Lancet 2, 1403. doi:10.1016/S0140-6736(76)91936-X
-
(1976)
Lancet
, vol.2
, pp. 1403
-
-
Davies, P.1
Maloney, A.J.2
-
20
-
-
77951540816
-
Caspase activation precedes and leads to tangles
-
doi:10.1038/nature08890
-
de Calignon, A., Fox, L. M., Pitstick, R., Carlson, G. A., Bacskai, B. J., Spires-Jones, T. L., et al. (2010). Caspase activation precedes and leads to tangles. Nature 464, 1201-1204. doi:10.1038/nature08890
-
(2010)
Nature
, vol.464
, pp. 1201-1204
-
-
de Calignon, A.1
Fox, L.M.2
Pitstick, R.3
Carlson, G.A.4
Bacskai, B.J.5
Spires-Jones, T.L.6
-
21
-
-
84857275902
-
Propagation of tau pathology in a model of early Alzheimer's disease
-
doi:10.1016/j.neuron.2011.11.033
-
de Calignon, A., Polydoro, M., Suarez-Calvet, M., William, C., Adamowicz, D. H., Kopeikina, K. J., et al. (2012). Propagation of tau pathology in a model of early Alzheimer's disease. Neuron 73, 685-697. doi:10.1016/j.neuron.2011.11.033
-
(2012)
Neuron
, vol.73
, pp. 685-697
-
-
de Calignon, A.1
Polydoro, M.2
Suarez-Calvet, M.3
William, C.4
Adamowicz, D.H.5
Kopeikina, K.J.6
-
22
-
-
77957815617
-
Tissue-nonspecific alkaline phosphatase promotes the neurotoxicity effect of extracellular tau
-
doi:10.1074/jbc.M110.145003
-
Diaz-Hernandez, M., Gomez-Ramos, A., Rubio, A., Gomez-Villafuertes, R., Naranjo, J. R., Miras-Portugal, M. T., et al. (2010). Tissue-nonspecific alkaline phosphatase promotes the neurotoxicity effect of extracellular tau. J. Biol. Chem. 285, 32539-32548. doi:10.1074/jbc.M110.145003
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 32539-32548
-
-
Diaz-Hernandez, M.1
Gomez-Ramos, A.2
Rubio, A.3
Gomez-Villafuertes, R.4
Naranjo, J.R.5
Miras-Portugal, M.T.6
-
23
-
-
0022896901
-
Tau protein function in living cells
-
doi:10.1083/jcb.103.6.2739
-
Drubin, D. G., and Kirschner, M. W. (1986). Tau protein function in living cells. J. Cell Biol. 103, 2739-2746. doi:10.1083/jcb.103.6.2739
-
(1986)
J. Cell Biol.
, vol.103
, pp. 2739-2746
-
-
Drubin, D.G.1
Kirschner, M.W.2
-
24
-
-
0029013930
-
Muscarinic acetylcholine receptors: signal transduction through multiple effectors
-
Felder, C. C. (1995). Muscarinic acetylcholine receptors: signal transduction through multiple effectors. FASEB J. 9, 619-625.
-
(1995)
FASEB J.
, vol.9
, pp. 619-625
-
-
Felder, C.C.1
-
25
-
-
67649273927
-
Propagation of tau misfolding from the outside to the inside of a cell
-
doi:10.1074/jbc.M808759200
-
Frost, B., Jacks, R. L., and Diamond, M. I. (2009). Propagation of tau misfolding from the outside to the inside of a cell. J. Biol. Chem. 284, 12845-12852. doi:10.1074/jbc.M808759200
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 12845-12852
-
-
Frost, B.1
Jacks, R.L.2
Diamond, M.I.3
-
26
-
-
0026595846
-
Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms
-
doi:10.1016/0896-6273(92)90117-V
-
Goedert, M., Spillantini, M. G., Cairns, N. J., and Crowther, R. A. (1992a). Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms. Neuron 8, 159-168. doi:10.1016/0896-6273(92)90117-V
-
(1992)
Neuron
, vol.8
, pp. 159-168
-
-
Goedert, M.1
Spillantini, M.G.2
Cairns, N.J.3
Crowther, R.A.4
-
27
-
-
0026512915
-
Cloning of a big tau microtubule-associated protein characteristic of the peripheral nervous system
-
doi:10.1073/pnas.89.5.1983
-
Goedert, M., Spillantini, M. G., and Crowther, R. A. (1992b). Cloning of a big tau microtubule-associated protein characteristic of the peripheral nervous system. Proc. Natl. Acad. Sci. U.S.A. 89, 1983-1987. doi:10.1073/pnas.89.5.1983
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 1983-1987
-
-
Goedert, M.1
Spillantini, M.G.2
Crowther, R.A.3
-
28
-
-
0024745894
-
Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease
-
doi:10.1016/0896-6273(89)90210-9
-
Goedert, M., Spillantini, M. G., Jakes, R., Rutherford, D., and Crowther, R. A. (1989). Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron 3, 519-526. doi:10.1016/0896-6273(89)90210-9
-
(1989)
Neuron
, vol.3
, pp. 519-526
-
-
Goedert, M.1
Spillantini, M.G.2
Jakes, R.3
Rutherford, D.4
Crowther, R.A.5
-
29
-
-
75949107662
-
Tau-knockout mice show reduced GSK3-induced hippocampal degeneration and learning deficits
-
doi:10.1016/j.nbd.2009.11.017
-
Gomez de Barreda, E., Perez, M., Gomez Ramos, P., De Cristobal, J., Martin-Maestro, P., Moran, A., et al. (2010). Tau-knockout mice show reduced GSK3-induced hippocampal degeneration and learning deficits. Neurobiol. Dis. 37, 622-629. doi:10.1016/j.nbd.2009.11.017
-
(2010)
Neurobiol. Dis.
, vol.37
, pp. 622-629
-
-
Gomez de Barreda, E.1
Perez, M.2
Gomez Ramos, P.3
De Cristobal, J.4
Martin-Maestro, P.5
Moran, A.6
-
30
-
-
0344653664
-
Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease
-
doi:10.1002/ana.410410106
-
Gomez-Isla, T., Hollister, R., West, H., Mui, S., Growdon, J. H., Petersen, R. C., et al. (1997). Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease. Ann. Neurol. 41, 17-24. doi:10.1002/ana.410410106
-
(1997)
Ann. Neurol.
, vol.41
, pp. 17-24
-
-
Gomez-Isla, T.1
Hollister, R.2
West, H.3
Mui, S.4
Growdon, J.H.5
Petersen, R.C.6
-
31
-
-
33747862732
-
Extracellular tau is toxic to neuronal cells
-
doi:10.1016/j.febslet.2006.07.078
-
Gomez-Ramos, A., Diaz-Hernandez, M., Cuadros, R., Hernandez, F., and Avila, J. (2006). Extracellular tau is toxic to neuronal cells. FEBS Lett. 580, 4842-4850. doi:10.1016/j.febslet.2006.07.078
-
(2006)
FEBS Lett.
, vol.580
, pp. 4842-4850
-
-
Gomez-Ramos, A.1
Diaz-Hernandez, M.2
Cuadros, R.3
Hernandez, F.4
Avila, J.5
-
32
-
-
69049090784
-
Characteristics and consequences of muscarinic receptor activation by tau protein
-
doi:10.1016/j.euroneuro.2009.04.006
-
Gomez-Ramos, A., Diaz-Hernandez, M., Rubio, A., Diaz-Hernandez, J. I., Miras-Portugal, M. T., and Avila, J. (2009). Characteristics and consequences of muscarinic receptor activation by tau protein. Eur. Neuropsychopharmacol. 19, 708-717. doi:10.1016/j.euroneuro.2009.04.006
-
(2009)
Eur. Neuropsychopharmacol.
, vol.19
, pp. 708-717
-
-
Gomez-Ramos, A.1
Diaz-Hernandez, M.2
Rubio, A.3
Diaz-Hernandez, J.I.4
Miras-Portugal, M.T.5
Avila, J.6
-
33
-
-
41149111293
-
Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells
-
doi:10.1016/j.mcn.2007.12.010
-
Gomez-Ramos, A., Diaz-Hernandez, M., Rubio, A., Miras-Portugal, M. T., and Avila, J. (2008). Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells. Mol. Cell. Neurosci. 37, 673-681. doi:10.1016/j.mcn.2007.12.010
-
(2008)
Mol. Cell. Neurosci.
, vol.37
, pp. 673-681
-
-
Gomez-Ramos, A.1
Diaz-Hernandez, M.2
Rubio, A.3
Miras-Portugal, M.T.4
Avila, J.5
-
34
-
-
0029161154
-
Localization and in situ phosphorylation state of nuclear tau
-
doi:10.1006/excr.1995.1323
-
Greenwood, J. A., and Johnson, G. V. (1995). Localization and in situ phosphorylation state of nuclear tau. Exp. Cell Res. 220, 332-337. doi:10.1006/excr.1995.1323
-
(1995)
Exp. Cell Res.
, vol.220
, pp. 332-337
-
-
Greenwood, J.A.1
Johnson, G.V.2
-
35
-
-
0022744803
-
Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology
-
doi:10.1073/pnas.83.13.4913
-
Grundke-Iqbal, I., Iqbal, K., Tung, Y. C., Quinlan, M., Wisniewski, H. M., and Binder, L. I. (1986). Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology. Proc. Natl. Acad. Sci. U.S.A. 83, 4913-4917. doi:10.1073/pnas.83.13.4913
-
(1986)
Proc. Natl. Acad. Sci. U.S.A.
, vol.83
, pp. 4913-4917
-
-
Grundke-Iqbal, I.1
Iqbal, K.2
Tung, Y.C.3
Quinlan, M.4
Wisniewski, H.M.5
Binder, L.I.6
-
36
-
-
61849088424
-
Tau phosphorylation: the therapeutic challenge for neurodegenerative disease
-
doi:10.1016/j.molmed.2009.01.003
-
Hanger, D. P., Anderton, B. H., and Noble, W. (2009). Tau phosphorylation: the therapeutic challenge for neurodegenerative disease. Trends. Mol. Med. 15, 112-119. doi:10.1016/j.molmed.2009.01.003
-
(2009)
Trends. Mol. Med.
, vol.15
, pp. 112-119
-
-
Hanger, D.P.1
Anderton, B.H.2
Noble, W.3
-
37
-
-
0024498630
-
Structure of the bovine tau gene: alternatively spliced transcripts generate a protein family
-
Himmler, A. (1989). Structure of the bovine tau gene: alternatively spliced transcripts generate a protein family. Mol. Cell. Biol. 9, 1389-1396.
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 1389-1396
-
-
Himmler, A.1
-
38
-
-
84872346089
-
Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy
-
doi:10.1523/JNEUROSCI.2642-12.2013
-
Iba, M., Guo, J. L., Mcbride, J. D., Zhang, B., Trojanowski, J. Q., and Lee, V. M. (2013). Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy. J. Neurosci. 33, 1024-1037. doi:10.1523/JNEUROSCI.2642-12.2013
-
(2013)
J. Neurosci.
, vol.33
, pp. 1024-1037
-
-
Iba, M.1
Guo, J.L.2
Mcbride, J.D.3
Zhang, B.4
Trojanowski, J.Q.5
Lee, V.M.6
-
39
-
-
77955322042
-
Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models
-
doi:10.1016/j.cell.2010.06.036
-
Ittner, L. M., Ke, Y. D., Delerue, F., Bi, M., Gladbach, A., Van Eersel, J., et al. (2010). Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models. Cell 142, 387-397. doi:10.1016/j.cell.2010.06.036
-
(2010)
Cell
, vol.142
, pp. 387-397
-
-
Ittner, L.M.1
Ke, Y.D.2
Delerue, F.3
Bi, M.4
Gladbach, A.5
Van Eersel, J.6
-
40
-
-
0026734744
-
Hm1 muscarinic cholinergic receptor internalization requires a domain in the third cytoplasmic loop
-
Lameh, J., Philip, M., Sharma, Y. K., Moro, O., Ramachandran, J., and Sadee, W. (1992). Hm1 muscarinic cholinergic receptor internalization requires a domain in the third cytoplasmic loop. J. Biol. Chem. 267, 13406-13412.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 13406-13412
-
-
Lameh, J.1
Philip, M.2
Sharma, Y.K.3
Moro, O.4
Ramachandran, J.5
Sadee, W.6
-
41
-
-
0023905288
-
The primary structure and heterogeneity of tau protein from mouse brain
-
doi:10.1126/science.3122323
-
Lee, G., Cowan, N., and Kirschner, M. (1988). The primary structure and heterogeneity of tau protein from mouse brain. Science 239, 285-288. doi:10.1126/science.3122323
-
(1988)
Science
, vol.239
, pp. 285-288
-
-
Lee, G.1
Cowan, N.2
Kirschner, M.3
-
42
-
-
84877927610
-
Changes in tau phosphorylation in hibernating rodents
-
doi:10.1002/jnr.23220
-
Leon-Espinosa, G., Garcia, E., Garcia-Escudero, V., Hernandez, F., Defelipe, J., and Avila, J. (2013). Changes in tau phosphorylation in hibernating rodents. J. Neurosci. Res. 91, 654-662. doi:10.1002/jnr.23220
-
(2013)
J. Neurosci. Res.
, vol.91
, pp. 654-662
-
-
Leon-Espinosa, G.1
Garcia, E.2
Garcia-Escudero, V.3
Hernandez, F.4
Defelipe, J.5
Avila, J.6
-
43
-
-
27944444956
-
Human protein tau represses DNA replication in vitro
-
doi:10.1016/j.bbagen.2005.08.014
-
Li, W., Wang, X. S., Qu, M. H., Liu, Y., and He, R. Q. (2005). Human protein tau represses DNA replication in vitro. Biochim. Biophys. Acta 1726, 280-286. doi:10.1016/j.bbagen.2005.08.014
-
(2005)
Biochim. Biophys. Acta
, vol.1726
, pp. 280-286
-
-
Li, W.1
Wang, X.S.2
Qu, M.H.3
Liu, Y.4
He, R.Q.5
-
44
-
-
84856454190
-
Trans-synaptic spread of tau pathology in vivo
-
doi:10.1371/journal.pone.0031302
-
Liu, L., Drouet, V., Wu, J. W., Witter, M. P., Small, S. A., Clelland, C., et al. (2012). Trans-synaptic spread of tau pathology in vivo. PLoS ONE 7:e31302. doi:10.1371/journal.pone.0031302
-
(2012)
PLoS ONE
, vol.7
-
-
Liu, L.1
Drouet, V.2
Wu, J.W.3
Witter, M.P.4
Small, S.A.5
Clelland, C.6
-
45
-
-
33947691643
-
Granular tau oligomers as intermediates of tau filaments
-
doi:10.1021/bi061359o
-
Maeda, S., Sahara, N., Saito, Y., Murayama, M., Yoshiike, Y., Kim, H., et al. (2007). Granular tau oligomers as intermediates of tau filaments. Biochemistry 46, 3856-3861. doi:10.1021/bi061359o
-
(2007)
Biochemistry
, vol.46
, pp. 3856-3861
-
-
Maeda, S.1
Sahara, N.2
Saito, Y.3
Murayama, M.4
Yoshiike, Y.5
Kim, H.6
-
46
-
-
0012510759
-
Amyloid plaque core protein in Alzheimer disease and Down syndrome
-
doi:10.1073/pnas.82.12.4245
-
Masters, C. L., Simms, G., Weinman, N. A., Multhaup, G., Mcdonald, B. L., and Beyreuther, K. (1985). Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc. Natl. Acad. Sci. U.S.A. 82, 4245-4249. doi:10.1073/pnas.82.12.4245
-
(1985)
Proc. Natl. Acad. Sci. U.S.A.
, vol.82
, pp. 4245-4249
-
-
Masters, C.L.1
Simms, G.2
Weinman, N.A.3
Multhaup, G.4
Mcdonald, B.L.5
Beyreuther, K.6
-
47
-
-
84857063878
-
Blocking effects of human tau on squid giant synapse transmission and its prevention by T-817 MA
-
doi:10.3389/fnsyn.2011.00003
-
Moreno, H., Choi, S., Yu, E., Brusco, J., Avila, J., Moreira, J. E., et al. (2011). Blocking effects of human tau on squid giant synapse transmission and its prevention by T-817 MA. Front. Synaptic Neurosci. 3:3. doi:10.3389/fnsyn.2011.00003
-
(2011)
Front. Synaptic Neurosci.
, vol.3
, pp. 3
-
-
Moreno, H.1
Choi, S.2
Yu, E.3
Brusco, J.4
Avila, J.5
Moreira, J.E.6
-
48
-
-
0029830646
-
Molecular evolution of tau protein: implications for Alzheimer's disease
-
doi:10.1046/j.1471-4159.1996.67041622.x
-
Nelson, P. T., Stefansson, K., Gulcher, J., and Saper, C. B. (1996). Molecular evolution of tau protein: implications for Alzheimer's disease. J. Neurochem. 67, 1622-1632. doi:10.1046/j.1471-4159.1996.67041622.x
-
(1996)
J. Neurochem.
, vol.67
, pp. 1622-1632
-
-
Nelson, P.T.1
Stefansson, K.2
Gulcher, J.3
Saper, C.B.4
-
49
-
-
79960956148
-
Biomarker-based dissection of neurodegenerative diseases
-
doi:10.1016/j.pneurobio.2011.04.006
-
Olsson, B., Zetterberg, H., Hampel, H., and Blennow, K. (2011). Biomarker-based dissection of neurodegenerative diseases. Prog. Neurobiol. 95, 520-534. doi:10.1016/j.pneurobio.2011.04.006
-
(2011)
Prog. Neurobiol.
, vol.95
, pp. 520-534
-
-
Olsson, B.1
Zetterberg, H.2
Hampel, H.3
Blennow, K.4
-
50
-
-
0242720372
-
Chronic lithium treatment decreases mutant tau protein aggregation in a transgenic mouse model
-
Perez, M., Hernandez, F., Lim, F., Diaz-Nido, J., and Avila, J. (2003). Chronic lithium treatment decreases mutant tau protein aggregation in a transgenic mouse model. J. Alzheimers Dis. 5, 301-308.
-
(2003)
J. Alzheimers Dis.
, vol.5
, pp. 301-308
-
-
Perez, M.1
Hernandez, F.2
Lim, F.3
Diaz-Nido, J.4
Avila, J.5
-
51
-
-
84856707794
-
Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease
-
doi:10.1074/jbc.M111.277061
-
Saman, S., Kim, W., Raya, M., Visnick, Y., Miro, S., Jackson, B., et al. (2012). Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. J. Biol. Chem. 287, 3842-3849. doi:10.1074/jbc.M111.277061
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 3842-3849
-
-
Saman, S.1
Kim, W.2
Raya, M.3
Visnick, Y.4
Miro, S.5
Jackson, B.6
-
52
-
-
0036830458
-
Aberrant tau phosphorylation by glycogen synthase kinase-3beta and JNK3 induces oligomeric tau fibrils in COS-7 cells
-
doi:10.1074/jbc.M202241200
-
Sato, S., Tatebayashi, Y., Akagi, T., Chui, D. H., Murayama, M., Miyasaka, T., et al. (2002). Aberrant tau phosphorylation by glycogen synthase kinase-3beta and JNK3 induces oligomeric tau fibrils in COS-7 cells. J. Biol. Chem. 277, 42060-42065. doi:10.1074/jbc.M202241200
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 42060-42065
-
-
Sato, S.1
Tatebayashi, Y.2
Akagi, T.3
Chui, D.H.4
Murayama, M.5
Miyasaka, T.6
-
53
-
-
84655176335
-
Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles.
-
doi:10.1016/j.febslet.2011.11.022
-
Simon, D., Garcia-Garcia, E., Royo, F., Falcon-Perez, J. M., and Avila, J. (2012). Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles. FEBS Lett. 586, 47-54. doi:10.1016/j.febslet.2011.11.022
-
(2012)
FEBS Lett.
, vol.586
, pp. 47-54
-
-
Simon, D.1
Garcia-Garcia, E.2
Royo, F.3
Falcon-Perez, J.M.4
Avila, J.5
-
54
-
-
84860354271
-
The protein phosphatase PP2A/Balpha binds to the microtubule-associated proteins Tau and MAP2 at a motif also recognized by the kinase Fyn: implications for tauopathies
-
doi:10.1074/jbc.M111.338681
-
Sontag, J. M., Nunbhakdi-Craig, V., White, C. L. 3rd, Halpain, S., and Sontag, E. (2012). The protein phosphatase PP2A/Balpha binds to the microtubule-associated proteins Tau and MAP2 at a motif also recognized by the kinase Fyn: implications for tauopathies. J. Biol. Chem. 287, 14984-14993. doi:10.1074/jbc.M111.338681
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 14984-14993
-
-
Sontag, J.M.1
Nunbhakdi-Craig, V.2
White, C.L.3
Halpain, S.4
Sontag, E.5
-
55
-
-
79953003312
-
Nuclear tau, a key player in neuronal DNA protection
-
doi:10.1074/jbc.M110.199976
-
Sultan, A., Nesslany, F., Violet, M., Begard, S., Loyens, A., Talahari, S., et al. (2011). Nuclear tau, a key player in neuronal DNA protection. J. Biol. Chem. 286, 4566-4575. doi:10.1074/jbc.M110.199976
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 4566-4575
-
-
Sultan, A.1
Nesslany, F.2
Violet, M.3
Begard, S.4
Loyens, A.5
Talahari, S.6
-
56
-
-
0029993245
-
Tau as a nucleolar protein in human nonneural cells in vitro and in vivo
-
doi:10.1007/BF02510035
-
Thurston, V. C., Zinkowski, R. P., and Binder, L. I. (1996). Tau as a nucleolar protein in human nonneural cells in vitro and in vivo. Chromosoma 105, 20-30. doi:10.1007/BF02510035
-
(1996)
Chromosoma
, vol.105
, pp. 20-30
-
-
Thurston, V.C.1
Zinkowski, R.P.2
Binder, L.I.3
-
58
-
-
0008538685
-
A protein factor essential for microtubule assembly
-
doi:10.1073/pnas.72.5.1858
-
Weingarten, M. D., Lockwood, A. H., Hwo, S. Y., and Kirschner, M. W. (1975). A protein factor essential for microtubule assembly. Proc. Natl. Acad. Sci. U.S.A. 72, 1858-1862. doi:10.1073/pnas.72.5.1858
-
(1975)
Proc. Natl. Acad. Sci. U.S.A.
, vol.72
, pp. 1858-1862
-
-
Weingarten, M.D.1
Lockwood, A.H.2
Hwo, S.Y.3
Kirschner, M.W.4
-
59
-
-
84872714502
-
Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons
-
doi:10.1074/jbc.M112.394528
-
Wu, J. W., Herman, M., Liu, L., Simoes, S., Acker, C. M., Figueroa, H., et al. (2012). Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons. J. Biol. Chem. 288, 1856-1870. doi:10.1074/jbc.M112.394528
-
(2012)
J. Biol. Chem.
, vol.288
, pp. 1856-1870
-
-
Wu, J.W.1
Herman, M.2
Liu, L.3
Simoes, S.4
Acker, C.M.5
Figueroa, H.6
-
60
-
-
33846538660
-
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
-
doi:10.1016/j.neuron.2007.01.010
-
Yoshiyama, Y., Higuchi, M., Zhang, B., Huang, S. M., Iwata, N., Saido, T. C., et al. (2007). Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model. Neuron 53, 337-351. doi:10.1016/j.neuron.2007.01.010
-
(2007)
Neuron
, vol.53
, pp. 337-351
-
-
Yoshiyama, Y.1
Higuchi, M.2
Zhang, B.3
Huang, S.M.4
Iwata, N.5
Saido, T.C.6
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