-
1
-
-
33747830764
-
Hepatocellular carcinoma pathogenesis: from genes to environment
-
Farazi PA, DePinho RA. Hepatocellular carcinoma pathogenesis: from genes to environment. Nat Rev Cancer 2006; 6: 674-687.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 674-687
-
-
Farazi, P.A.1
DePinho, R.A.2
-
2
-
-
58249110568
-
Role of bile acids and bile acid receptors in metabolic regulation
-
Lefebvre P, Cariou B, Lien F, Kuipers F, Staels B. Role of bile acids and bile acid receptors in metabolic regulation. Physiol Rev 2009; 89: 147-191.
-
(2009)
Physiol Rev
, vol.89
, pp. 147-191
-
-
Lefebvre, P.1
Cariou, B.2
Lien, F.3
Kuipers, F.4
Staels, B.5
-
3
-
-
0029046931
-
Identification of a nuclear receptor that is activated by farnesol metabolites
-
Forman BM, Goode E, Chen J etal. Identification of a nuclear receptor that is activated by farnesol metabolites. Cell 1995; 81: 687-693.
-
(1995)
Cell
, vol.81
, pp. 687-693
-
-
Forman, B.M.1
Goode, E.2
Chen, J.3
-
4
-
-
77952673509
-
Bile acids and their nuclear receptor FXR: relevance for hepatobiliary and gastrointestinal disease
-
Gadaleta RM, van Mil SW, Oldenburg B, Siersema PD, Klomp LW, van Erpecum KJ. Bile acids and their nuclear receptor FXR: relevance for hepatobiliary and gastrointestinal disease. Biochim Biophys Acta 2010; 1801: 683-692.
-
(2010)
Biochim Biophys Acta
, vol.1801
, pp. 683-692
-
-
Gadaleta, R.M.1
van Mil, S.W.2
Oldenburg, B.3
Siersema, P.D.4
van Klomp, L.W.5
Erpecum, K.J.6
-
5
-
-
79953173235
-
Nuclear receptors as new perspective for the management of liver diseases
-
Trauner M, Halilbasic E. Nuclear receptors as new perspective for the management of liver diseases. Gastroenterology 2011; 140: 1120-1125.
-
(2011)
Gastroenterology
, vol.140
, pp. 1120-1125
-
-
Trauner, M.1
Halilbasic, E.2
-
7
-
-
33645821043
-
Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration
-
Huang W, Ma K, Zhang J etal. Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration. Science 2006; 312: 233-236.
-
(2006)
Science
, vol.312
, pp. 233-236
-
-
Huang, W.1
Ma, K.2
Zhang, J.3
-
8
-
-
77950616155
-
Farnesoid X receptor alleviates age-related proliferation defects in regenerating mouse livers by activating forkhead box m1b transcription
-
Chen WD, Wang YD, Zhang L etal. Farnesoid X receptor alleviates age-related proliferation defects in regenerating mouse livers by activating forkhead box m1b transcription. Hepatology 2010; 51: 953-962.
-
(2010)
Hepatology
, vol.51
, pp. 953-962
-
-
Chen, W.D.1
Wang, Y.D.2
Zhang, L.3
-
9
-
-
79958273142
-
Nuclear bile acid receptor FXR in the hepatic regeneration
-
Chen WD, Wang YD, Meng Z, Zhang L, Huang W. Nuclear bile acid receptor FXR in the hepatic regeneration. Biochim Biophys Acta 2011; 1812: 888-892.
-
(2011)
Biochim Biophys Acta
, vol.1812
, pp. 888-892
-
-
Chen, W.D.1
Wang, Y.D.2
Meng, Z.3
Zhang, L.4
Huang, W.5
-
10
-
-
34447098081
-
Spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice
-
Kim I, Morimura K, Shah Y, Yang Q, Ward JM, Gonzalez FJ. Spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice. Carcinogenesis 2007; 28: 940-946.
-
(2007)
Carcinogenesis
, vol.28
, pp. 940-946
-
-
Kim, I.1
Morimura, K.2
Shah, Y.3
Yang, Q.4
Ward, J.M.5
Gonzalez, F.J.6
-
11
-
-
33847044019
-
Spontaneous development of liver tumors in the absence of the bile acid receptor farnesoid X receptor
-
Yang F, Huang X, Yi T, Yen Y, Moore DD, Huang W. Spontaneous development of liver tumors in the absence of the bile acid receptor farnesoid X receptor. Cancer Res 2007; 67: 863-867.
-
(2007)
Cancer Res
, vol.67
, pp. 863-867
-
-
Yang, F.1
Huang, X.2
Yi, T.3
Yen, Y.4
Moore, D.D.5
Huang, W.6
-
12
-
-
36549048284
-
Farnesol, a mevalonate pathway intermediate, stimulates MCF-7 breast cancer cell growth through farnesoid-X-receptor-mediated estrogen receptor activation
-
Journe F, Laurent G, Chaboteaux C etal. Farnesol, a mevalonate pathway intermediate, stimulates MCF-7 breast cancer cell growth through farnesoid-X-receptor-mediated estrogen receptor activation. Breast Cancer Res Treat 2008; 107: 49-61.
-
(2008)
Breast Cancer Res Treat
, vol.107
, pp. 49-61
-
-
Journe, F.1
Laurent, G.2
Chaboteaux, C.3
-
13
-
-
79952695558
-
Farnesoid X receptor, overexpressed in pancreatic cancer with lymph node metastasis promotes cell migration and invasion
-
Lee JY, Lee KT, Lee JK etal. Farnesoid X receptor, overexpressed in pancreatic cancer with lymph node metastasis promotes cell migration and invasion. Br J Cancer 2011; 104: 1027-1037.
-
(2011)
Br J Cancer
, vol.104
, pp. 1027-1037
-
-
Lee, J.Y.1
Lee, K.T.2
Lee, J.K.3
-
14
-
-
84860330199
-
Hepatocarcinogenesis in FXR-/- mice mimics human HCC progression that operates through HNF1alpha regulation of FXR expression
-
Liu N, Meng Z, Lou G etal. Hepatocarcinogenesis in FXR-/- mice mimics human HCC progression that operates through HNF1alpha regulation of FXR expression. Mol Endocrinol 2012; 26: 775-785.
-
(2012)
Mol Endocrinol
, vol.26
, pp. 775-785
-
-
Liu, N.1
Meng, Z.2
Lou, G.3
-
15
-
-
84862026667
-
No correlation between the expression of FXR and genes involved in multidrug resistance phenotype of primary liver tumors
-
Martinez-Becerra P, Vaquero J, Romero MR etal. No correlation between the expression of FXR and genes involved in multidrug resistance phenotype of primary liver tumors. Mol Pharm 2012; 9: 1693-1704.
-
(2012)
Mol Pharm
, vol.9
, pp. 1693-1704
-
-
Martinez-Becerra, P.1
Vaquero, J.2
Romero, M.R.3
-
16
-
-
79959491395
-
Increased activation of the Wnt/beta-catenin pathway in spontaneous hepatocellular carcinoma observed in farnesoid X receptor knockout mice
-
Wolfe A, Thomas A, Edwards G, Jaseja R, Guo GL, Apte U. Increased activation of the Wnt/beta-catenin pathway in spontaneous hepatocellular carcinoma observed in farnesoid X receptor knockout mice. J Pharmacol Exp Ther 2011; 338: 12-21.
-
(2011)
J Pharmacol Exp Ther
, vol.338
, pp. 12-21
-
-
Wolfe, A.1
Thomas, A.2
Edwards, G.3
Jaseja, R.4
Guo, G.L.5
Apte, U.6
-
17
-
-
77955179596
-
-
4th edn. Lyon: International Agency for Research on Cancer (IARC)
-
Theise ND, Gurado MP, Franceschi S, Hytiroglou P, Kudo M. WHO Classification of Tumours of the Digestive System, 4th edn. Lyon: International Agency for Research on Cancer (IARC), 2010.
-
(2010)
WHO Classification of Tumours of the Digestive System
-
-
Theise, N.D.1
Gurado, M.P.2
Franceschi, S.3
Hytiroglou, P.4
Kudo, M.5
-
18
-
-
3543031024
-
The bile acid nuclear receptor FXR and the bile acid binding protein IBABP are differently expressed in colon cancer
-
De Gottardi A, Touri F, Maurer CA etal. The bile acid nuclear receptor FXR and the bile acid binding protein IBABP are differently expressed in colon cancer. Dig Dis Sci 2004; 49: 982-989.
-
(2004)
Dig Dis Sci
, vol.49
, pp. 982-989
-
-
De Gottardi, A.1
Touri, F.2
Maurer, C.A.3
-
19
-
-
84859101637
-
Expression of the nuclear bile acid receptor/farnesoid X receptor is reduced in human colon carcinoma compared to nonneoplastic mucosa independent from site and may be associated with adverse prognosis
-
Lax S, Schauer G, Prein K etal. Expression of the nuclear bile acid receptor/farnesoid X receptor is reduced in human colon carcinoma compared to nonneoplastic mucosa independent from site and may be associated with adverse prognosis. Int J Cancer 2012; 130: 2232-2239.
-
(2012)
Int J Cancer
, vol.130
, pp. 2232-2239
-
-
Lax, S.1
Schauer, G.2
Prein, K.3
-
20
-
-
84859874520
-
Downregulation of human farnesoid X receptor by miR-421 promotes proliferation and migration of hepatocellular carcinoma cells
-
Zhang Y, Gong W, Dai S etal. Downregulation of human farnesoid X receptor by miR-421 promotes proliferation and migration of hepatocellular carcinoma cells. Mol Cancer Res 2012; 10: 516-522.
-
(2012)
Mol Cancer Res
, vol.10
, pp. 516-522
-
-
Zhang, Y.1
Gong, W.2
Dai, S.3
-
21
-
-
84655169703
-
MicroRNA-421 functions as an oncogenic miRNA in biliary tract cancer through down-regulating farnesoid X receptor expression
-
Zhong XY, Yu JH, Zhang WG etal. MicroRNA-421 functions as an oncogenic miRNA in biliary tract cancer through down-regulating farnesoid X receptor expression. Gene 2012; 493: 44-51.
-
(2012)
Gene
, vol.493
, pp. 44-51
-
-
Zhong, X.Y.1
Yu, J.H.2
Zhang, W.G.3
-
22
-
-
7644244675
-
The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis
-
Fiorucci S, Antonelli E, Rizzo G etal. The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis. Gastroenterology 2004; 127: 1497-1512.
-
(2004)
Gastroenterology
, vol.127
, pp. 1497-1512
-
-
Fiorucci, S.1
Antonelli, E.2
Rizzo, G.3
-
23
-
-
73549089485
-
Farnesoid X receptor critically determines the fibrotic response in mice but is expressed to a low extent in human hepatic stellate cells and periductal myofibroblasts
-
Fickert P, Fuchsbichler A, Moustafa T etal. Farnesoid X receptor critically determines the fibrotic response in mice but is expressed to a low extent in human hepatic stellate cells and periductal myofibroblasts. Am J Pathol 2009; 175: 2392-2405.
-
(2009)
Am J Pathol
, vol.175
, pp. 2392-2405
-
-
Fickert, P.1
Fuchsbichler, A.2
Moustafa, T.3
-
24
-
-
79959305674
-
Roles of microRNA-29a in the antifibrotic effect of farnesoid X receptor in hepatic stellate cells
-
Li J, Zhang Y, Kuruba R etal. Roles of microRNA-29a in the antifibrotic effect of farnesoid X receptor in hepatic stellate cells. Mol Pharmacol 2011; 80: 191-200.
-
(2011)
Mol Pharmacol
, vol.80
, pp. 191-200
-
-
Li, J.1
Zhang, Y.2
Kuruba, R.3
-
25
-
-
33750535007
-
The farnesoid X receptor is expressed in breast cancer and regulates apoptosis and aromatase expression
-
Swales KE, Korbonits M, Carpenter R, Walsh DT, Warner TD, Bishop-Bailey D. The farnesoid X receptor is expressed in breast cancer and regulates apoptosis and aromatase expression. Cancer Res 2006; 66: 10120-10126.
-
(2006)
Cancer Res
, vol.66
, pp. 10120-10126
-
-
Swales, K.E.1
Korbonits, M.2
Carpenter, R.3
Walsh, D.T.4
Warner, T.D.5
Bishop-Bailey, D.6
-
26
-
-
84870888675
-
Critical role of farnesoid X receptor (FXR) for hepatocellular carcinoma cell proliferation
-
Fujino T, Takeuchi A, Maruko-Ohtake A etal. Critical role of farnesoid X receptor (FXR) for hepatocellular carcinoma cell proliferation. J Biochem 2012; 152: 577-586.
-
(2012)
J Biochem
, vol.152
, pp. 577-586
-
-
Fujino, T.1
Takeuchi, A.2
Maruko-Ohtake, A.3
-
27
-
-
67349099717
-
Association between farnesoid X receptor expression and cell proliferation in estrogen receptor-positive luminal-like breast cancer from postmenopausal patients
-
Journe F, Durbecq V, Chaboteaux C etal. Association between farnesoid X receptor expression and cell proliferation in estrogen receptor-positive luminal-like breast cancer from postmenopausal patients. Breast Cancer Res Treat 2009; 115: 523-535.
-
(2009)
Breast Cancer Res Treat
, vol.115
, pp. 523-535
-
-
Journe, F.1
Durbecq, V.2
Chaboteaux, C.3
-
28
-
-
84862010208
-
Chemoresistance can be induced by bile acid-independent activation of FXR in liver and intestinal cancer cells
-
Monte MJ, Serrano MA, Herraez E etal. Chemoresistance can be induced by bile acid-independent activation of FXR in liver and intestinal cancer cells. Hepatology 2011; 54: 713-714.
-
(2011)
Hepatology
, vol.54
, pp. 713-714
-
-
Monte, M.J.1
Serrano, M.A.2
Herraez, E.3
-
29
-
-
34548696626
-
Effect of preoperative transcatheter arterial chemoembolization on proliferation of hepatocellular carcinoma cells
-
Xiao EH, Li JQ, Huang JF. Effect of preoperative transcatheter arterial chemoembolization on proliferation of hepatocellular carcinoma cells. World J Gastroenterol 2007; 13: 4509-4513.
-
(2007)
World J Gastroenterol
, vol.13
, pp. 4509-4513
-
-
Xiao, E.H.1
Li, J.Q.2
Huang, J.F.3
|