메뉴 건너뛰기




Volumn 4 JUL, Issue , 2013, Pages

Reduced hippocampal dentate cell proliferation and impaired spatial memory performance in aged-epileptic rats

Author keywords

Aging; Epilepsy; Neurogenesis; Pilocarpine; Water maze

Indexed keywords

BROXURIDINE; PILOCARPINE;

EID: 84883500061     PISSN: None     EISSN: 16642295     Source Type: Journal    
DOI: 10.3389/fneur.2013.00106     Document Type: Review
Times cited : (13)

References (73)
  • 1
    • 79952575607 scopus 로고    scopus 로고
    • The neurobiology of cognitive disorders in temporal lobe epilepsy
    • doi:10.1038/nrneurol.2011.3
    • Bell B, Lin J, Seidenberg M, Hermann B. The neurobiology of cognitive disorders in temporal lobe epilepsy. Nat Rev Neurol (2011) 7:154-64. doi:10.1038/nrneurol.2011.3
    • (2011) Nat Rev Neurol , vol.7 , pp. 154-164
    • Bell, B.1    Lin, J.2    Seidenberg, M.3    Hermann, B.4
  • 2
    • 0018872987 scopus 로고
    • Memory function in focal epilepsy: a comparison of non-surgical, unilateral temporal lobe and frontal lobe samples
    • doi:10.1016/S0010-9452(80)80026-8
    • Delaney R, Rosen A, Mattson R, Novelly R. Memory function in focal epilepsy: a comparison of non-surgical, unilateral temporal lobe and frontal lobe samples. Cortex (1980) 16:103-17. doi:10.1016/S0010-9452(80)80026-8
    • (1980) Cortex , vol.16 , pp. 103-117
    • Delaney, R.1    Rosen, A.2    Mattson, R.3    Novelly, R.4
  • 3
    • 5644282561 scopus 로고    scopus 로고
    • Chronic epilepsy and cognition
    • doi:10.1016/S1474-4422(04)00906-8
    • Elger C, Helmstaedter C, Kurthen M. Chronic epilepsy and cognition. Lancet Neurol (2004) 3:663-72. doi:10.1016/S1474-4422(04)00906-8
    • (2004) Lancet Neurol , vol.3 , pp. 663-672
    • Elger, C.1    Helmstaedter, C.2    Kurthen, M.3
  • 4
    • 0032977348 scopus 로고    scopus 로고
    • Learning and memory impairment in patients with temporal lobe epilepsy: relation to presence, type, and location of brain lesion
    • doi:10.1111/j.1528-1157.1999.tb00797.x
    • Giovagnoli A, Avanzini G. Learning and memory impairment in patients with temporal lobe epilepsy: relation to presence, type, and location of brain lesion. Epilepsia (1999) 40:904-11. doi:10.1111/j.1528-1157.1999.tb00797.x
    • (1999) Epilepsia , vol.40 , pp. 904-911
    • Giovagnoli, A.1    Avanzini, G.2
  • 5
    • 0033000664 scopus 로고    scopus 로고
    • Long term effects of refractory temporal lobe epilepsy on cognitive abilities: a cross sectional study
    • doi:10.1136/jnnp.67.1.44
    • Jokeit H, Ebner A. Long term effects of refractory temporal lobe epilepsy on cognitive abilities: a cross sectional study. J Neurol Neurosurg Psychiatr (1999) 67:44-50. doi:10.1136/jnnp.67.1.44
    • (1999) J Neurol Neurosurg Psychiatr , vol.67 , pp. 44-50
    • Jokeit, H.1    Ebner, A.2
  • 7
    • 58149146109 scopus 로고    scopus 로고
    • Responses to pain in school-aged children with experience in a neonatal intensive care unit: cognitive aspects and maternal influences
    • doi:10.1016/j.ejpain.2008.03.004
    • Hohmeister J, Demirakça S, Zohsel K, Flor H, Hermann C. Responses to pain in school-aged children with experience in a neonatal intensive care unit: cognitive aspects and maternal influences. Eur J Pain (2009) 13:94-101. doi:10.1016/j.ejpain.2008.03.004
    • (2009) Eur J Pain , vol.13 , pp. 94-101
    • Hohmeister, J.1    Demirakça, S.2    Zohsel, K.3    Flor, H.4    Hermann, C.5
  • 8
    • 0027143716 scopus 로고
    • Circuit mechanisms of seizures in the pilocarpine model of chronic epilepsy: cell loss and mossy fiber sprouting
    • doi:10.1111/j.1528-1157.1993.tb02123.x
    • Mello L, Cavalheiro E, Tan A, Kupfer W, Pretorius J, Babb T, et al. Circuit mechanisms of seizures in the pilocarpine model of chronic epilepsy: cell loss and mossy fiber sprouting. Epilepsia (1993) 34:985-95. doi:10.1111/j.1528-1157.1993.tb02123.x
    • (1993) Epilepsia , vol.34 , pp. 985-995
    • Mello, L.1    Cavalheiro, E.2    Tan, A.3    Kupfer, W.4    Pretorius, J.5    Babb, T.6
  • 9
    • 0030907041 scopus 로고    scopus 로고
    • Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus
    • Parent J, Yu T, Leibowitz R, Geschwind D, Sloviter R, Lowenstein D. Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus. J Neurosci (1997) 17:3727-38.
    • (1997) J Neurosci , vol.17 , pp. 3727-3738
    • Parent, J.1    Yu, T.2    Leibowitz, R.3    Geschwind, D.4    Sloviter, R.5    Lowenstein, D.6
  • 10
    • 0032550154 scopus 로고    scopus 로고
    • Kainic acid increases the proliferation of granule cell progenitors in the dentate gyrus of the adult rat
    • doi:10.1016/S0006-8993(98)00030-4
    • Gray W, Sundstrom L. Kainic acid increases the proliferation of granule cell progenitors in the dentate gyrus of the adult rat. Brain Res (1998) 790:52-9. doi:10.1016/S0006-8993(98)00030-4
    • (1998) Brain Res , vol.790 , pp. 52-59
    • Gray, W.1    Sundstrom, L.2
  • 11
    • 0038169897 scopus 로고    scopus 로고
    • Dentate granule cell neurogenesis after seizures induced by pentylenetrazol in rats
    • doi:10.1016/S0006-8993(03)02438-7
    • Jiang W, Wan Q, Zhang Z, Wang W, Huang Y, Rao Z, et al. Dentate granule cell neurogenesis after seizures induced by pentylenetrazol in rats. Brain Res (2003) 977:141-8. doi:10.1016/S0006-8993(03)02438-7
    • (2003) Brain Res , vol.977 , pp. 141-148
    • Jiang, W.1    Wan, Q.2    Zhang, Z.3    Wang, W.4    Huang, Y.5    Rao, Z.6
  • 12
    • 29944442275 scopus 로고    scopus 로고
    • Aberrant seizure-induced neurogenesis in experimental temporal lobe epilepsy
    • doi:10.1002/ana.20699
    • Parent J, Elliott R, Pleasure S, Barbaro N, Lowenstein D. Aberrant seizure-induced neurogenesis in experimental temporal lobe epilepsy. Ann Neurol (2006) 59:81-91. doi:10.1002/ana.20699
    • (2006) Ann Neurol , vol.59 , pp. 81-91
    • Parent, J.1    Elliott, R.2    Pleasure, S.3    Barbaro, N.4    Lowenstein, D.5
  • 13
    • 0142185315 scopus 로고    scopus 로고
    • Perforant path activation of ectopic granule cells that are born after pilocarpine-induced seizures
    • doi:10.1016/S0306-4522(03)00481-0
    • Scharfman H, Sollas A, Berger R, Goodman J, Pierce J. Perforant path activation of ectopic granule cells that are born after pilocarpine-induced seizures. Neuroscience (2003) 121:1017-29. doi:10.1016/S0306-4522(03)00481-0
    • (2003) Neuroscience , vol.121 , pp. 1017-1029
    • Scharfman, H.1    Sollas, A.2    Berger, R.3    Goodman, J.4    Pierce, J.5
  • 14
    • 0032577413 scopus 로고    scopus 로고
    • Kindling-induced neurogenesis in the dentate gyrus of the rat
    • doi:10.1016/S0304-3940(98)00355-3
    • Scott B, Wang S, Burnham W, De Boni U, Wojtowicz J. Kindling-induced neurogenesis in the dentate gyrus of the rat. Neurosci Lett (1998) 248:73-6. doi:10.1016/S0304-3940(98)00355-3
    • (1998) Neurosci Lett , vol.248 , pp. 73-76
    • Scott, B.1    Wang, S.2    Burnham, W.3    De Boni, U.4    Wojtowicz, J.5
  • 15
    • 0033806998 scopus 로고    scopus 로고
    • Neurogenesis in the dentate gyrus of the rat following electroconvulsive shock seizures
    • doi:10.1006/exnr.2000.7458
    • Scott B, Wojtowicz J, Burnham W. Neurogenesis in the dentate gyrus of the rat following electroconvulsive shock seizures. Exp Neurol (2000) 165:231-6. doi:10.1006/exnr.2000.7458
    • (2000) Exp Neurol , vol.165 , pp. 231-236
    • Scott, B.1    Wojtowicz, J.2    Burnham, W.3
  • 16
    • 0034002585 scopus 로고    scopus 로고
    • Cell damage and neurogenesis in the dentate granule cell layer of adult rats after pilocarpine- or kainate-induced status epilepticus
    • doi:10.1002/(SICI)1098-1063(2000)10:2<169::AID-HIPO6>3.0.CO;2-W
    • Covolan L, Ribeiro L, Longo B, Mello L. Cell damage and neurogenesis in the dentate granule cell layer of adult rats after pilocarpine- or kainate-induced status epilepticus. Hippocampus (2000) 10:169-80. doi:10.1002/(SICI)1098-1063(2000)10:2<169::AID-HIPO6>3.0.CO;2-W
    • (2000) Hippocampus , vol.10 , pp. 169-180
    • Covolan, L.1    Ribeiro, L.2    Longo, B.3    Mello, L.4
  • 17
    • 75149160465 scopus 로고    scopus 로고
    • Decreased neuronal differentiation of newly generated cells underlies reduced hippocampal neurogenesis in chronic temporal lobe epilepsy
    • doi:10.1002/hipo.20594
    • Hattiangady B, Shetty A. Decreased neuronal differentiation of newly generated cells underlies reduced hippocampal neurogenesis in chronic temporal lobe epilepsy. Hippocampus (2009) 20:97-112. doi:10.1002/hipo.20594
    • (2009) Hippocampus , vol.20 , pp. 97-112
    • Hattiangady, B.1    Shetty, A.2
  • 18
    • 33745698913 scopus 로고    scopus 로고
    • Potential role for adult neurogenesis in the encoding of time in new memories
    • doi:10.1038/nn1707
    • Aimone J, Wiles J, Gage F. Potential role for adult neurogenesis in the encoding of time in new memories. Nat Neurosci (2006) 9:727-32. doi:10.1038/nn1707
    • (2006) Nat Neurosci , vol.9 , pp. 727-732
    • Aimone, J.1    Wiles, J.2    Gage, F.3
  • 19
    • 0029863342 scopus 로고    scopus 로고
    • Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation
    • Kuhn H, Dickinson-Anson H, Gage F. Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J Neurosci (1996) 16:2027-33.
    • (1996) J Neurosci , vol.16 , pp. 2027-2033
    • Kuhn, H.1    Dickinson-Anson, H.2    Gage, F.3
  • 20
    • 0035834806 scopus 로고    scopus 로고
    • Spatial learning deficits without hippocampal neuronal loss in a model of early-onset epilepsy
    • doi:10.1016/S0306-4522(01)00327-X
    • Lee C, Hannay J, Hrachovy R, Rashid S, Antalffy B, Swann JW. Spatial learning deficits without hippocampal neuronal loss in a model of early-onset epilepsy. Neuroscience (2001) 107:71-84. doi:10.1016/S0306-4522(01)00327-X
    • (2001) Neuroscience , vol.107 , pp. 71-84
    • Lee, C.1    Hannay, J.2    Hrachovy, R.3    Rashid, S.4    Antalffy, B.5    Swann, J.W.6
  • 21
    • 0025105576 scopus 로고
    • Learning impairment in chronic epileptic rats following pilocarpine-induced status epilepticus
    • Leite J, Nakamura E, Lemos T, Masur J, Cavalheiro E. Learning impairment in chronic epileptic rats following pilocarpine-induced status epilepticus. Braz J Med Biol Res (1990) 23:681-3.
    • (1990) Braz J Med Biol Res , vol.23 , pp. 681-683
    • Leite, J.1    Nakamura, E.2    Lemos, T.3    Masur, J.4    Cavalheiro, E.5
  • 22
    • 0029560904 scopus 로고
    • Deficits in radial arm maze performance in kindled rats: evidence for long-lasting memory dysfunction induced by repeated brief seizures
    • Sutula T, Lauersdorf S, Lynch M, Jurgella C, Woodard A. Deficits in radial arm maze performance in kindled rats: evidence for long-lasting memory dysfunction induced by repeated brief seizures. J Neurosci (1995) 15:8295-301.
    • (1995) J Neurosci , vol.15 , pp. 8295-8301
    • Sutula, T.1    Lauersdorf, S.2    Lynch, M.3    Jurgella, C.4    Woodard, A.5
  • 23
    • 0042668324 scopus 로고    scopus 로고
    • Production of new cells in the rat dentate gyrus over the lifespan: relation to cognitive decline
    • doi:10.1046/j.1460-9568.2003.02733.x
    • Bizon J, Gallagher M. Production of new cells in the rat dentate gyrus over the lifespan: relation to cognitive decline. Eur J Neurosci (2003) 18:215-9. doi:10.1046/j.1460-9568.2003.02733.x
    • (2003) Eur J Neurosci , vol.18 , pp. 215-219
    • Bizon, J.1    Gallagher, M.2
  • 24
    • 13844257516 scopus 로고    scopus 로고
    • Neurogenesis in a rat model of age-related cognitive decline
    • doi:10.1111/j.1474-9728.2004.00099.x
    • Bizon J, Lee H, Gallagher M. Neurogenesis in a rat model of age-related cognitive decline. Aging Cell (2004) 3:227-34. doi:10.1111/j.1474-9728.2004.00099.x
    • (2004) Aging Cell , vol.3 , pp. 227-234
    • Bizon, J.1    Lee, H.2    Gallagher, M.3
  • 25
    • 0344198502 scopus 로고    scopus 로고
    • Spatial memory performances of aged rats in the water maze predict levels of hippocampa neurogenesis
    • doi:10.1073/pnas.2334169100
    • Drapeau E, Mayo W, Aurousseau C, Le Moal M, Piazza PV, Abrous DN. Spatial memory performances of aged rats in the water maze predict levels of hippocampa neurogenesis. Proc Natl Acad Sci U S A (2003) 100:14385-90. doi:10.1073/pnas.2334169100
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 14385-90
    • Drapeau, E.1    Mayo, W.2    Aurousseau, C.3    Le Moal, M.4    Piazza, P.V.5    Abrous, D.N.6
  • 26
    • 33646145503 scopus 로고    scopus 로고
    • The aging hippocampus: a multi-level analysis in the rat
    • doi:10.1016/j.neuroscience.2006.01.040
    • Driscol I, Howard S, Stone J, Mofils M, Tomanek B, Brooks W, et al. The aging hippocampus: a multi-level analysis in the rat. Neuroscience (2006) 139:1173-85. doi:10.1016/j.neuroscience.2006.01.040
    • (2006) Neuroscience , vol.139 , pp. 1173-1185
    • Driscol, I.1    Howard, S.2    Stone, J.3    Mofils, M.4    Tomanek, B.5    Brooks, W.6
  • 27
    • 78049467264 scopus 로고    scopus 로고
    • Low proliferation and differentiation capacities of adult hippocampal stem cells correlate with memory dysfunction in humans
    • doi:10.1093/brain/awq215
    • Coras R, Siebzehnrubl F, Pauli E, Huttner H, Njunting M, Kobow K, et al. Low proliferation and differentiation capacities of adult hippocampal stem cells correlate with memory dysfunction in humans. Brain (2010) 133:3359-72. doi:10.1093/brain/awq215
    • (2010) Brain , vol.133 , pp. 3359-3372
    • Coras, R.1    Siebzehnrubl, F.2    Pauli, E.3    Huttner, H.4    Njunting, M.5    Kobow, K.6
  • 28
    • 0036455153 scopus 로고    scopus 로고
    • Genetic determinants of adult hippocampal neurogenesis correlate with acquisition, but not probe trial performance, in the water maze task
    • doi:10.1046/j.1460-9568.2002.02042.x
    • Kempermann G, Gage F. Genetic determinants of adult hippocampal neurogenesis correlate with acquisition, but not probe trial performance, in the water maze task. Eur J Neurosci (2002) 16:129-36. doi:10.1046/j.1460-9568.2002.02042.x
    • (2002) Eur J Neurosci , vol.16 , pp. 129-136
    • Kempermann, G.1    Gage, F.2
  • 29
    • 25444507923 scopus 로고    scopus 로고
    • Morris water maze learning in two rat strains increases the expression of the polysialylated form of the neural cell adhesion molecule in the dentate gyrus but has no effect on hippocampal neurogenesis
    • doi:10.1037/0735-7044.119.4.926
    • Van der Borght K, Wallinga A, Luiten P, Eggen B, Van der Zee E. Morris water maze learning in two rat strains increases the expression of the polysialylated form of the neural cell adhesion molecule in the dentate gyrus but has no effect on hippocampal neurogenesis. Behav Neurosci (2005) 119:926-32. doi:10.1037/0735-7044.119.4.926
    • (2005) Behav Neurosci , vol.119 , pp. 926-932
    • Van der Borght, K.1    Wallinga, A.2    Luiten, P.3    Eggen, B.4    Van der Zee, E.5
  • 30
    • 0037471433 scopus 로고    scopus 로고
    • Hippocampal cell genesis does not correlate with spatial learning ability in aged rats
    • doi:10.1002/cne.10616
    • Merrill D, Karim R, Darraq M, Chiba A, Tuszynski M. Hippocampal cell genesis does not correlate with spatial learning ability in aged rats. J Comp Neurol (2003) 459:201-7. doi:10.1002/cne.10616
    • (2003) J Comp Neurol , vol.459 , pp. 201-207
    • Merrill, D.1    Karim, R.2    Darraq, M.3    Chiba, A.4    Tuszynski, M.5
  • 31
    • 77956618801 scopus 로고    scopus 로고
    • Basal dendrites are present in newly born dentate granule cells of young but not aged pilocarpine-treated chronic epileptic rats
    • doi:10.1016/j
    • Avanzi R, Cavarsan C, Santos JG Jr., Hamani C, Mello LE, Covolan L. Basal dendrites are present in newly born dentate granule cells of young but not aged pilocarpine-treated chronic epileptic rats. Neuroscience (2010) 170:687-91. doi:10.1016/j
    • (2010) Neuroscience , vol.170 , pp. 687-691
    • Avanzi, R.1    Cavarsan, C.2    Santos Jr., J.G.3    Hamani, C.4    Mello, L.E.5    Covolan, L.6
  • 32
    • 84877317712 scopus 로고    scopus 로고
    • m1 Acetylcholine receptor expression is decreased in hippocampal CA1 region of aged epileptic animals
    • Cavarsan C, Avanzi R, Queiroz C, Xavier G, Mello L, Covolan L. m1 Acetylcholine receptor expression is decreased in hippocampal CA1 region of aged epileptic animals. Aging Dis (2011) 2:301-7.
    • (2011) Aging Dis , vol.2 , pp. 301-307
    • Cavarsan, C.1    Avanzi, R.2    Queiroz, C.3    Xavier, G.4    Mello, L.5    Covolan, L.6
  • 33
    • 0015309163 scopus 로고
    • Modification of seizure activity by electrical stimulation
    • doi:10.1016/0013-4694(72)90177-0
    • Racine R. Modification of seizure activity by electrical stimulation. II. Motor seizure. Electroencephalogr Clin Neurophysiol (1972) 32:281-94. doi:10.1016/0013-4694(72)90177-0
    • (1972) II. Motor seizure. Electroencephalogr Clin Neurophysiol , vol.32 , pp. 281-294
    • Racine, R.1
  • 35
    • 80052524399 scopus 로고    scopus 로고
    • Seizure frequency in pilocarpine-treated rats is independent circadian rhythm
    • doi:10.1111/j.1528-1167.2011.03200.x
    • Bajorat R, Wilde M, Sellmann T, Kirschstein T, Kohling R. Seizure frequency in pilocarpine-treated rats is independent circadian rhythm. Epilepsia (2011) 59:118-22. doi:10.1111/j.1528-1167.2011.03200.x
    • (2011) Epilepsia , vol.59 , pp. 118-122
    • Bajorat, R.1    Wilde, M.2    Sellmann, T.3    Kirschstein, T.4    Kohling, R.5
  • 36
    • 80052823828 scopus 로고    scopus 로고
    • Modeling epileptogenesis and temporal lobe epilepsy in a non-human primate
    • doi:10.1016/j.eplepsyres.2011.04.015
    • Perez-Mendes P, Blanco M, Calcagnotto M, Cinini S, Bachiega J, Papoti D, et al. Modeling epileptogenesis and temporal lobe epilepsy in a non-human primate. Epilepsy Res (2011) 96:45-57. doi:10.1016/j.eplepsyres.2011.04.015
    • (2011) Epilepsy Res , vol.96 , pp. 45-57
    • Perez-Mendes, P.1    Blanco, M.2    Calcagnotto, M.3    Cinini, S.4    Bachiega, J.5    Papoti, D.6
  • 37
    • 0019957779 scopus 로고
    • Place navigation impaired in rats with hippocampal lesions
    • doi:10.1038/297681a0
    • Morris R, Garrud P, Rawlins J, and O'Keefe J. Place navigation impaired in rats with hippocampal lesions. Nature (1982) 297:681-3. doi:10.1038/297681a0
    • (1982) Nature , vol.297 , pp. 681-683
    • Morris, R.1    Garrud, P.2    Rawlins, J.3    O'Keefe, J.4
  • 38
    • 84862162271 scopus 로고    scopus 로고
    • The appropriateness of unbiased optical fractionators to assess cell proliferation in the adult hippocampus
    • doi:10.3389/fnins.2011.00140
    • Noori H, Fornal C. The appropriateness of unbiased optical fractionators to assess cell proliferation in the adult hippocampus. Front Neurosci (2011) 5:140. doi:10.3389/fnins.2011.00140
    • (2011) Front Neurosci , vol.5 , pp. 140
    • Noori, H.1    Fornal, C.2
  • 39
    • 0033982064 scopus 로고    scopus 로고
    • Temporal profile of neuronal injury following pilocarpine or kainic acid-induced status epilepticus
    • doi:10.1016/S0920-1211(99)00119-9
    • Covolan L, Mello L. Temporal profile of neuronal injury following pilocarpine or kainic acid-induced status epilepticus. Epilepsy Res (2000) 39:133-52. doi:10.1016/S0920-1211(99)00119-9
    • (2000) Epilepsy Res , vol.39 , pp. 133-152
    • Covolan, L.1    Mello, L.2
  • 40
    • 0018344553 scopus 로고
    • Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat
    • doi:10.1037/h0077579
    • Barnes C. Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat. J Comp Physiol Psychol (1979) 93:74-104. doi:10.1037/h0077579
    • (1979) J Comp Physiol Psychol , vol.93 , pp. 74-104
    • Barnes, C.1
  • 41
    • 0030639472 scopus 로고    scopus 로고
    • The use of animal models to study the effects of aging on cognition
    • doi:10.1146/annurev.psych.48.1.339
    • Gallagher M, Rapp P. The use of animal models to study the effects of aging on cognition. Annu Rev Psychol (1997) 48:339-70. doi:10.1146/annurev.psych.48.1.339
    • (1997) Annu Rev Psychol , vol.48 , pp. 339-370
    • Gallagher, M.1    Rapp, P.2
  • 42
    • 0024332271 scopus 로고
    • Individual differences in aging: behavioral and neurobiological correlates
    • doi:10.1016/S0197-4580(89)80008-9
    • Markowska A, Stone W, Ingram D, Reynolds J, Gold P, Conti L, et al. Individual differences in aging: behavioral and neurobiological correlates. Neurobiol Aging (1989) 10:31-43. doi:10.1016/S0197-4580(89)80008-9
    • (1989) Neurobiol Aging , vol.10 , pp. 31-43
    • Markowska, A.1    Stone, W.2    Ingram, D.3    Reynolds, J.4    Gold, P.5    Conti, L.6
  • 43
    • 79960789804 scopus 로고    scopus 로고
    • Hippocampal-dependent spatial memory in the water maze is preserved in an experimental model of temporal lobe epilepsy in rats
    • doi:10.1371/journal.pone.0022372
    • Inostroza M, Cid E, Brotons-Mas J, Gal B, Aivar P, Uzcategui Y, et al. Hippocampal-dependent spatial memory in the water maze is preserved in an experimental model of temporal lobe epilepsy in rats. PLoS ONE (2011) 6:e22372. doi:10.1371/journal.pone.0022372
    • (2011) PLoS ONE , vol.6
    • Inostroza, M.1    Cid, E.2    Brotons-Mas, J.3    Gal, B.4    Aivar, P.5    Uzcategui, Y.6
  • 44
    • 44849140113 scopus 로고    scopus 로고
    • Glutamate receptor-mediated restoration of experience-dependent place field expansion plasticity in aged rats
    • doi:10.1037/0735-7044.122.3.535
    • Burke S, Maurer A, Yang Z, Navratilova Z, Barnes C. Glutamate receptor-mediated restoration of experience-dependent place field expansion plasticity in aged rats. Behav Neurosci (2008) 122:535-48. doi:10.1037/0735-7044.122.3.535
    • (2008) Behav Neurosci , vol.122 , pp. 535-548
    • Burke, S.1    Maurer, A.2    Yang, Z.3    Navratilova, Z.4    Barnes, C.5
  • 45
    • 0030744211 scopus 로고    scopus 로고
    • Experience-dependent, asymmetric expansion of hippocampal place fields
    • doi:10.1073/pnas.94.16.8918
    • Mehta M, Barnes C, McNaughton B. Experience-dependent, asymmetric expansion of hippocampal place fields. Proc Natl Acad Sci U S A (1997) 94:8918-21. doi:10.1073/pnas.94.16.8918
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 8918-8921
    • Mehta, M.1    Barnes, C.2    McNaughton, B.3
  • 46
    • 0033681558 scopus 로고    scopus 로고
    • Experience-dependent asymmetric shape of hippocampal receptive fields
    • doi:10.1016/S0896-6273(00)81072-7
    • Mehta M, Quirk M, Wilson M. Experience-dependent asymmetric shape of hippocampal receptive fields. Neuron (2000) 25:707-15. doi:10.1016/S0896-6273(00)81072-7
    • (2000) Neuron , vol.25 , pp. 707-715
    • Mehta, M.1    Quirk, M.2    Wilson, M.3
  • 47
    • 0029907977 scopus 로고    scopus 로고
    • Hippocampal CA3 region predicts memory sequences: accounting for the phase precession of place cells
    • doi:10.1101/lm.3.2-3.279
    • Jensen O, Lisman J. Hippocampal CA3 region predicts memory sequences: accounting for the phase precession of place cells. Learn Mem (1996) 3:279-87. doi:10.1101/lm.3.2-3.279
    • (1996) Learn Mem , vol.3 , pp. 279-287
    • Jensen, O.1    Lisman, J.2
  • 48
    • 50349084734 scopus 로고    scopus 로고
    • Sequence reactivation in the hippocampus is impaired in aged rats
    • doi:10.1523/JNEUROSCI.1265-08.2008
    • Gerrard J, Burke S, McNaughton B, Barnes C. Sequence reactivation in the hippocampus is impaired in aged rats. J Neurosci (2008) 28:7883-90. doi:10.1523/JNEUROSCI.1265-08.2008
    • (2008) J Neurosci , vol.28 , pp. 7883-7890
    • Gerrard, J.1    Burke, S.2    McNaughton, B.3    Barnes, C.4
  • 49
    • 29044432058 scopus 로고    scopus 로고
    • Behavioral changes resulting from the administration of cycloheximide in the pilocarpine model of epilepsy
    • doi:10.1016/j.brainres.2005.09.037
    • Dos Santos J, Longo B, Blanco M, Menezes de Oliveira M, Mello L. Behavioral changes resulting from the administration of cycloheximide in the pilocarpine model of epilepsy. Brain Res (2005) 1066:37-48. doi:10.1016/j.brainres.2005.09.037
    • (2005) Brain Res , vol.1066 , pp. 37-48
    • Dos Santos, J.1    Longo, B.2    Blanco, M.3    Menezes de Oliveira, M.4    Mello, L.5
  • 50
    • 0032880365 scopus 로고    scopus 로고
    • Cognitive functions after pilocarpine-induced status epilepticus: changes during silent period precede appearance of spontaneous recurrent seizures
    • doi:10.1111/j.1528-1157.1999.tb00845.x
    • Hort J, Brozek G, Mares P, Langmeier M, Komarek V. Cognitive functions after pilocarpine-induced status epilepticus: changes during silent period precede appearance of spontaneous recurrent seizures. Epilepsia (1999) 40:1177-83. doi:10.1111/j.1528-1157.1999.tb00845.x
    • (1999) Epilepsia , vol.40 , pp. 1177-1183
    • Hort, J.1    Brozek, G.2    Mares, P.3    Langmeier, M.4    Komarek, V.5
  • 51
    • 0031738370 scopus 로고    scopus 로고
    • Status epilepticus causes long-term NMDA receptor-dependent behavioral changes and cognitive deficits
    • doi:10.1111/j.1528-1157.1998.tb01305.x
    • Rice A, Floyd C, Lyeth B, Hamm R, DeLorenzo R. Status epilepticus causes long-term NMDA receptor-dependent behavioral changes and cognitive deficits. Epilepsia (1998) 39:1148-57. doi:10.1111/j.1528-1157.1998.tb01305.x
    • (1998) Epilepsia , vol.39 , pp. 1148-1157
    • Rice, A.1    Floyd, C.2    Lyeth, B.3    Hamm, R.4    DeLorenzo, R.5
  • 52
    • 65649153301 scopus 로고    scopus 로고
    • Early deficits in spatial memory and theta rhythm in experimental temporal lobe epilepsy
    • doi:10.1523/JNEUROSCI.4699-08.2009
    • Chauvière L, Rafrafi N, Thinus-Blanc C, Bartolomei F, Esclapez M, Bernard C. Early deficits in spatial memory and theta rhythm in experimental temporal lobe epilepsy. J Neurosci (2009) 29:5402-10. doi:10.1523/JNEUROSCI.4699-08.2009
    • (2009) J Neurosci , vol.29 , pp. 5402-5410
    • Chauvière, L.1    Rafrafi, N.2    Thinus-Blanc, C.3    Bartolomei, F.4    Esclapez, M.5    Bernard, C.6
  • 53
    • 4344658358 scopus 로고    scopus 로고
    • Synchronization of neural oscillations as a possible mechanism underlying episodic memory: a study of theta rhythm in the hippocampus
    • doi:10.1142/S0219635204000488
    • Yamaguchi Y, Aota Y, Sato N, Wagatsuma H, Wu Z. Synchronization of neural oscillations as a possible mechanism underlying episodic memory: a study of theta rhythm in the hippocampus. J Integr Neurosci (2004) 3:143-57. doi:10.1142/S0219635204000488
    • (2004) J Integr Neurosci , vol.3 , pp. 143-157
    • Yamaguchi, Y.1    Aota, Y.2    Sato, N.3    Wagatsuma, H.4    Wu, Z.5
  • 54
    • 0033124284 scopus 로고    scopus 로고
    • Age-related changes in rat hippocampal theta rhythms: a difference between type 1 and type 2 theta
    • doi:10.1292/jvms.61.543
    • Abe Y, Toyosawa K. Age-related changes in rat hippocampal theta rhythms: a difference between type 1 and type 2 theta. J Vet Med Sci (1999) 61:543-8. doi:10.1292/jvms.61.543
    • (1999) J Vet Med Sci , vol.61 , pp. 543-548
    • Abe, Y.1    Toyosawa, K.2
  • 55
    • 30344469358 scopus 로고    scopus 로고
    • Rhinal-hippocampal connectivity determines memory formation during sleep
    • doi:10.1093/brain/awh647
    • Fell J, Fernandez G, Lutz M, Kockelmann E, Burr W, Schaller C, et al. Rhinal-hippocampal connectivity determines memory formation during sleep. Brain (2006) 129:108-14. doi:10.1093/brain/awh647
    • (2006) Brain , vol.129 , pp. 108-114
    • Fell, J.1    Fernandez, G.2    Lutz, M.3    Kockelmann, E.4    Burr, W.5    Schaller, C.6
  • 56
    • 0035203556 scopus 로고    scopus 로고
    • Human memory formation is accompanied by rhinal-hippocampalcoupling and decoupling
    • doi:10.1038/nn759
    • Fell J, Klaver P, Lehnertz K, Grunwald T, Schaller C, Elger C, et al. Human memory formation is accompanied by rhinal-hippocampalcoupling and decoupling. Nat Neurosci (2001) 4:1259-64. doi:10.1038/nn759
    • (2001) Nat Neurosci , vol.4 , pp. 1259-1264
    • Fell, J.1    Klaver, P.2    Lehnertz, K.3    Grunwald, T.4    Schaller, C.5    Elger, C.6
  • 57
    • 0031768421 scopus 로고    scopus 로고
    • Is partial epilepsy progressive?
    • doi:10.1111/j.1528-1157.1998.tb01310.x
    • Holmes M, Dodrill C, Wilkus R, Ojemann L, Ojemann G. Is partial epilepsy progressive?. Epilepsia (1998) 39:1189-93. doi:10.1111/j.1528-1157.1998.tb01310.x
    • (1998) Epilepsia , vol.39 , pp. 1189-1193
    • Holmes, M.1    Dodrill, C.2    Wilkus, R.3    Ojemann, L.4    Ojemann, G.5
  • 58
    • 0141484571 scopus 로고    scopus 로고
    • Chronic epilepsy and cognition: a longitudinal study in temporal lobe epilepsy
    • doi:10.1002/ana.10692
    • Helmstaedter C, Kurthen M, Lux S, Reuber M, Elger C. Chronic epilepsy and cognition: a longitudinal study in temporal lobe epilepsy. Ann Neurol (2003) 54:425-32. doi:10.1002/ana.10692
    • (2003) Ann Neurol , vol.54 , pp. 425-432
    • Helmstaedter, C.1    Kurthen, M.2    Lux, S.3    Reuber, M.4    Elger, C.5
  • 59
    • 0001159822 scopus 로고
    • Are new neurons formed in the brains of adult mammals?
    • doi:10.1126/science.135.3509.1127
    • Altman J. Are new neurons formed in the brains of adult mammals?. Science (1962) 135:1127-8. doi:10.1126/science.135.3509.1127
    • (1962) Science , vol.135 , pp. 1127-1128
    • Altman, J.1
  • 61
    • 0037006799 scopus 로고    scopus 로고
    • Functional integration of adult-born neurons
    • doi:10.1016/S0960-9822(02)00771-6
    • Carlén M, Cassidy R, Brismar H, Smith G, Enquist L, and Frisén J. Functional integration of adult-born neurons. Curr Biol (2002) 12:606-8. doi:10.1016/S0960-9822(02)00771-6
    • (2002) Curr Biol , vol.12 , pp. 606-608
    • Carlén, M.1    Cassidy, R.2    Brismar, H.3    Smith, G.4    Enquist, L.5    Frisén, J.6
  • 62
    • 0346120444 scopus 로고    scopus 로고
    • Adult-born hippocampal neurons mature into activity-dependent responsiveness
    • doi:10.1111/j.1460-9568.2003.02986.x
    • Jessberger S, Kempermann G. Adult-born hippocampal neurons mature into activity-dependent responsiveness. Eur J Neurosci (2003) 18:2707-12. doi:10.1111/j.1460-9568.2003.02986.x
    • (2003) Eur J Neurosci , vol.18 , pp. 2707-2712
    • Jessberger, S.1    Kempermann, G.2
  • 63
    • 2442642871 scopus 로고    scopus 로고
    • Enhanced synaptic plasticity in newly generated granule cells of the adult hippocampus
    • doi:10.1038/nature02553
    • Schmidt-Hieber C, Jonas P, Bischofberger J. Enhanced synaptic plasticity in newly generated granule cells of the adult hippocampus. Nature (2004) 429:184-7. doi:10.1038/nature02553
    • (2004) Nature , vol.429 , pp. 184-187
    • Schmidt-Hieber, C.1    Jonas, P.2    Bischofberger, J.3
  • 65
    • 3242689804 scopus 로고    scopus 로고
    • Milestones of neuronal development in the adult hippocampus
    • doi:10.1016/j.tins.2004.05.013
    • Kempermann G, Jessberger S, Steiner B, Kronenberg G. Milestones of neuronal development in the adult hippocampus. Trends Neurosci (2004) 27:447-52. doi:10.1016/j.tins.2004.05.013
    • (2004) Trends Neurosci , vol.27 , pp. 447-452
    • Kempermann, G.1    Jessberger, S.2    Steiner, B.3    Kronenberg, G.4
  • 66
    • 33745684603 scopus 로고    scopus 로고
    • Hippocampal neurogenesis is not required for behavioral effects of environmental enrichment
    • doi:10.1038/nn1696
    • Meshi D, Drew M, Saxe M, Ansorge M, David D, Santarelli L, et al. Hippocampal neurogenesis is not required for behavioral effects of environmental enrichment. Nat Neurosci (2006) 9:729-31. doi:10.1038/nn1696
    • (2006) Nat Neurosci , vol.9 , pp. 729-731
    • Meshi, D.1    Drew, M.2    Saxe, M.3    Ansorge, M.4    David, D.5    Santarelli, L.6
  • 67
    • 0013784893 scopus 로고
    • Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats
    • doi:10.1002/cne.901240303
    • Altman J, Das G. Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. J Comp Neurol (1965) 124:319-36. doi:10.1002/cne.901240303
    • (1965) J Comp Neurol , vol.124 , pp. 319-336
    • Altman, J.1    Das, G.2
  • 68
    • 0037334125 scopus 로고    scopus 로고
    • NMDA receptor antagonist treatment increases the production of new neurons in the aged rat hippocampus
    • doi:10.1016/S0197-4580(02)00096-9
    • Nacher J, Alonso-Llosa G, Rosell D, McEwen B. NMDA receptor antagonist treatment increases the production of new neurons in the aged rat hippocampus. Neurobiol Aging (2003) 24:273-84. doi:10.1016/S0197-4580(02)00096-9
    • (2003) Neurobiol Aging , vol.24 , pp. 273-284
    • Nacher, J.1    Alonso-Llosa, G.2    Rosell, D.3    McEwen, B.4
  • 69
    • 0030612186 scopus 로고    scopus 로고
    • Apoptosis and proliferation of dentate gyrus neurons after single and intermittent limbic seizures
    • doi:10.1073/pnas.94.19.10432
    • Bengzon J, Kokaia Z, Elmér E, Nanobashvili A, Kokaia M, Lindvall O. Apoptosis and proliferation of dentate gyrus neurons after single and intermittent limbic seizures. Proc Natl Acad Sci U S A (1997) 94:10432-7. doi:10.1073/pnas.94.19.10432
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 10432-7
    • Bengzon, J.1    Kokaia, Z.2    Elmér, E.3    Nanobashvili, A.4    Kokaia, M.5    Lindvall, O.6
  • 70
    • 9644289380 scopus 로고    scopus 로고
    • Chronic temporal lobe epilepsy is associated with severely declined dentate neurogenesis in the adult hippocampus
    • doi:10.1016/j.nbd.2004.08.008
    • Hattiangady B, Rao M, Shetty A. Chronic temporal lobe epilepsy is associated with severely declined dentate neurogenesis in the adult hippocampus. Neurobiol Dis (2004) 17:473-90. doi:10.1016/j.nbd.2004.08.008
    • (2004) Neurobiol Dis , vol.17 , pp. 473-490
    • Hattiangady, B.1    Rao, M.2    Shetty, A.3
  • 71
    • 65549125564 scopus 로고    scopus 로고
    • Neural stem and progenitor cells retain their potential for proliferation and differentiation into functional neurons despite lower number in aged brain
    • doi:10.1523/JNEUROSCI.6003-08.2009
    • Ahlenius H, Visan V, Kokaia M, Lindvall O, Kokaia Z. Neural stem and progenitor cells retain their potential for proliferation and differentiation into functional neurons despite lower number in aged brain. J Neurosci (2009) 29:4408-19. doi:10.1523/JNEUROSCI.6003-08.2009
    • (2009) J Neurosci , vol.29 , pp. 4408-4419
    • Ahlenius, H.1    Visan, V.2    Kokaia, M.3    Lindvall, O.4    Kokaia, Z.5
  • 72
    • 51849100364 scopus 로고    scopus 로고
    • Status epilepticus during old age is not associated with enhanced hippocampal neurogenesis
    • doi:10.1002/hipo.20449
    • Rao M, Hattiangady B, Shetty A. Status epilepticus during old age is not associated with enhanced hippocampal neurogenesis. Hippocampus (2008) 18:931-44. doi:10.1002/hipo.20449
    • (2008) Hippocampus , vol.18 , pp. 931-944
    • Rao, M.1    Hattiangady, B.2    Shetty, A.3
  • 73
    • 84866614721 scopus 로고    scopus 로고
    • Astrocyte alterations in the hippocampus following pilocarpine-induced seizures in aged rats
    • Arisi G, Ruch M, Foresti M, Mukherjee S, Ribak C, Shapiro L. Astrocyte alterations in the hippocampus following pilocarpine-induced seizures in aged rats. Aging Dis (2011) 2:294-300.
    • (2011) Aging Dis , vol.2 , pp. 294-300
    • Arisi, G.1    Ruch, M.2    Foresti, M.3    Mukherjee, S.4    Ribak, C.5    Shapiro, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.