Actin stimulates reduction of the MICAL-2 monooxygenase domain

Biochemistry

Volumn 52, Issue 35, 2013, Pages 6076-6084

  McDonald, Claudia A ^a   Liu, Ying Yi ^a   Palfey, Bruce A ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLAVIN-DEPENDENT; FULL-LENGTH ENZYMES; KINETIC ISOTOPE EFFECTS; PROSTATE CANCERS; REDUCED PYRIDINE NUCLEOTIDES; REDUCTION KINETICS; REGULATORY BEHAVIOR; WASTEFUL CONSUMPTION;

AMINO ACIDS; AROMATIC COMPOUNDS; AROMATIZATION; ENZYMES; ISOTOPES;

PROTEINS;

ACTIN; F ACTIN; FLAVINE NUCLEOTIDE; ISOTOPE; METHIONINE; MICAL 2 PROTEIN; OXYGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SULFUR; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME BINDING; ENZYME KINETICS; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; REDUCTION; REDUCTION KINETICS; REGULATORY MECHANISM;

ACTINS; ANIMALS; BASE SEQUENCE; DNA PRIMERS; KINETICS; MICE; MICROTUBULE-ASSOCIATED PROTEINS; MIXED FUNCTION OXYGENASES; MODELS, MOLECULAR; NAD; OXIDATION-REDUCTION; STEREOISOMERISM;

EID: 84883479331     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi4008462     Document Type: Article

References (26)

1. Pak, C. W., Flynn, K. C., and Bamburg, J. R. (2008) Actin-binding proteins take the reins in growth cones Nat. Rev. Neurosci. 9, 136-147
2. Zhou, Y., Gunput, R. A., Adolfs, Y., and Pasterkamp, R. J. (2011) MICALs in control of the cytoskeleton, exocytosis, and cell death Cell. Mol. Life Sci. 68, 4033-4044
3. Terman, J. R., Mao, T., Pasterkamp, R. J., Yu, H. H., and Kolodkin, A. L. (2002) MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion Cell 109, 887-900
4. Ashida, S., Furihata, M., Katagiri, T., Tamura, K., Anazawa, Y., Yoshioka, H., Miki, T., Fujioka, T., Shuin, T., Nakamura, Y., and Nakagawa, H. (2006) Expression of novel molecules, MICAL2-PV (MICAL2 prostate cancer variants), increases with high Gleason score and prostate cancer progression Clin. Cancer Res. 12, 2767-2773
5. Zucchini, D., Caprini, G., Pasterkamp, R. J., Tedeschi, G., and Vanoni, M. A. (2011) Kinetic and spectroscopic characterization of the putative monooxygenase domain of human MICAL-1 Arch. Biochem. Biophys. 515, 1-13
6. Palfey, B. A. and McDonald, C. A. (2010) Control of catalysis in flavin-dependent monooxygenases Arch. Biochem. Biophys. 493, 26-36
7. van Berkel, W. J., Kamerbeek, N. M., and Fraaije, M. W. (2006) Flavoprotein monooxygenases, a diverse class of oxidative biocatalysts J. Biotechnol. 124, 670-689
8. Siebold, C., Berrow, N., Walter, T. S., Harlos, K., Owens, R. J., Stuart, D. I., Terman, J. R., Kolodkin, A. L., Pasterkamp, R. J., and Jones, E. Y. (2005) High-resolution structure of the catalytic region of MICAL (molecule interacting with CasL), a multidomain flavoenzyme-signaling molecule Proc. Natl. Acad. Sci. U. S. A. 102, 16836-16841
9. Nadella, M., Bianchet, M. A., Gabelli, S. B., Barrila, J., and Amzel, L. M. (2005) Structure and activity of the axon guidance protein MICAL Proc. Natl. Acad. Sci. U. S. A. 102, 16830-16835
10. Hung, R. J., Pak, C. W., and Terman, J. R. (2011) Direct redox regulation of F-actin assembly and disassembly by Mical Science 334, 1710-1713
11. Stols, L., Gu, M., Dieckman, L., Raffen, R., Collart, F. R., and Donnelly, M. I. (2002) A new vector for high-throughput, ligation-independent cloning encoding a tobacco etch virus protease cleavage site Protein Expression Purif. 25, 8-15
12. Pardee, J. D. and Spudich, J. A. (1982) Purification of muscle actin Methods Enzymol. 85 (Pt B) 164-181
13. Ottolina, G., Riva, S., Carrea, G., Danieli, B., and Buckmann, A. F. (1989) Enzymatic synthesis of [4R-2H]NAD (P)H and [4S-2H]NAD(P)H and determination of the stereospecificity of 7 alpha- and 12 alpha hydroxysteroid dehydrogenase Biochim. Biophys. Acta 998, 173-178
14. Rider, L. W., Ottosen, M. B., Gattis, S. G., and Palfey, B. A. (2009) Mechanism of dihydrouridine synthase 2 from yeast and the importance of modifications for efficient tRNA reduction J. Biol. Chem. 284, 10324-10333
15. Wu, J. T., Wu, L. H., and Knight, J. A. (1986) Stability of NADPH: effect of various factors on the kinetics of degradation Clin. Chem. 32, 314-319
16. Palfey, B. A. (2003) in Time Resolved Spectral Analysis (Johnson, K. A., Ed.), pp 203-207, Oxford University Press, New York.
17. Strickland, S., Palmer, G., and Massey, V. (1975) Determination of dissociation constants and specific rate constants of enzyme-substrate (or protein-ligand) interactions from rapid reaction kinetic data J. Biol. Chem. 250, 4048-4052
18. Massey, V. (1990) in Flavins and Flavoproteins (Curti, B., Ronchi, S., and Zanetti, G., Ed.), pp 59-66, Walter de Gruyter, Berlin, Germany.
19. Minnaert, K. (1965) Measurement of the equilibrium constant of the reaction between cytochrome c and cytochrome a Biochim. Biophys. Acta 110, 42-56
20. Entsch, B., Palfey, B. A., Ballou, D. P., and Massey, V. (1991) Catalytic function of tyrosine residues in para-hydroxybenzoate hydroxylase as determined by the study of site-directed mutants J. Biol. Chem. 266, 17341-17349
21. Clark, W. M. (1960) Oxidation-Reduction Potentials of Organic Systems, The Williams & Wilkins Company, Baltimore, MD.
22. Hung, R. J., Yazdani, U., Yoon, J., Wu, H., Yang, T., Gupta, N., Huang, Z., van Berkel, W. J., and Terman, J. R. (2010) Mical links semaphorins to F-actin disassembly Nature 463, 823-827
23. Landgraf, M., Bossing, T., Technau, G. M., and Bate, M. (1997) The origin, location, and projections of the embryonic abdominal motorneurons of Drosophila J. Neurosci. 17, 9642-9655
24. Huang, X. Q. and Miller, W. (1991) A Time-Efficient, Linear-Space Local Similarity Algorithm Adv. Appl. Math. 12, 337-357
25. Moran, G. R., Entsch, B., Palfey, B. A., and Ballou, D. P. (1996) Evidence for flavin movement in the function of p-hydroxybenzoate hydroxylase from studies of the mutant Arg220Lys Biochemistry 35, 9278-9285
26. Schmidt, E. F., Shim, S. O., and Strittmatter, S. M. (2008) Release of MICAL autoinhibition by semaphorin-plexin signaling promotes interaction with collapsin response mediator protein J. Neurosci. 28, 2287-2297