Evidence for flavin movement in the function of p-hydroxybenzoate hydroxylase from studies of the mutant Arg220Lys

Biochemistry

Volumn 35, Issue 28, 1996, Pages 9278-9285

  Moran, Graham R ^a,b   Entsch, Barrie ^a   Palfey, Bruce A ^c   Ballou, David P ^c  

^a UNIVERSITY OF NEW ENGLAND   (Australia)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYBENZOATE 3 MONOOXYGENASE; ARGININE; FLAVINE ADENINE NUCLEOTIDE; LYSINE; MUTANT PROTEIN;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME STABILITY; ENZYME SUBSTRATE; PRIORITY JOURNAL;

4-HYDROXYBENZOATE-3-MONOOXYGENASE; ARGININE; BINDING SITES; CATALYSIS; FLAVIN-ADENINE DINUCLEOTIDE; FLAVINS; HYDROGEN-ION CONCENTRATION; KINETICS; LYSINE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; MUTATION; NADP; OXIDATION-REDUCTION; PARABENS; PROTEIN CONFORMATION; SPECTROPHOTOMETRY;

EID: 0029936955     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi960360s     Document Type: Article

References (36)

1. Anderson, R. F. (1982) in Flavins and Flavoproteins 1981 (Massey, V., & Williams, C. H., Eds.) pp 278-283, Elsevier North Holland, New York.
2. DiMarco, A., Averhoff, B., Kim, E. E., & Ornston, L. N. (1993) Gene 125, 25-33.
3. Entsch, B. (1990) Methods Enzymol. 188, 138-147.
4. Entsch, B., & van Berkel, W. J. H. (1995) FASEB J. 9, 476-483.
5. Entsch, B., Ballou, D. P., & Massey, V. (1976) J. Biol. Chem. 251, 2550-2563.
6. Entsch, B., Nan, Y., Weaich, K., & Scott, K. F. (1988) Gene 71, 279-291.
7. Entsch, B., Palfey, B. A., Ballou, D. P., & Massey, V. (1991) J. Biol. Chem. 266, 17341-17349.
8. Entsch, B., Palfey, B. A., Lumberg, M., Ballou, D. P., & Massey, V. (1994) in Flavins and Flavoproteins 1993 (Yagi, K., Ed.) pp 211-220, de Gruyter, Berlin.
9. Eppink, M. H. M., Scheuder, H. A., & van Berkel, W. J. H. (1995) Eur. J. Biochem. 231, 157-165.
10. Eschrich, K., van der Bolt, F., de Kok, A., & van Berkel, W. J. H. (1993) Eur. J. Biochem. 216, 137-146.
11. Gatti, D. L., Palfey, B. A., Lah, M. S., Entsch, B., Massey, V., Ballou, D. P., & Ludwig, M. L. (1994) Science 266, 110-114.
12. Gatti, D. L., Entsch, B., Ballou, D. P., & Ludwig, M. L. (1996) Biochemistry 35, 567-578.
13. Gibson, Q. H., Swoboda, B. E. P., & Massey, V. (1964) J. Biol. Chem. 239, 3927-3934.
14. Howell, L. G., Spector, T., & Massey, V. (1972) J. Biol. Chem. 247, 4340-4350.
15. Husain, M., & Massey, V. (1979) J. Biol. Chem. 254, 6657-6666.
16. Kemal, C., & Bruice, T. C. (1977) J. Am. Chem. Soc. 99, 7064-7067.
17. Kunkel, T. A., Roberts, J. D., & Zakour, R. A. (1987) Methods Enzymol. 154, 367-382.
18. Lah, M. S., Palfey, B. A., Schreuder, H. A., & Ludwig, M. L. (1994a) Biochemistry 33, 1555-1564.
19. Lah, M. S., Gatti, D., Schreuder, H. A., Palfey, B. A., & Ludwig, M. L. (1994b) in Flavins and Flavoproteins 1993 (Yagi, K., Ed.) pp 221-229, de Gruyter, Berlin.
20. Massey, V. (1990) in Flavins and Flavoproteins 1990 (Curti, B., Ronchi, S., & Zanetti, G., Eds.) pp 59-66, de Gruyter, Berlin.
21. McCammon, J. A., & Harvey, S. C. (1987) Dynamics of Proteins and Nucleic Acids, Cambridge University Press, Cambridge.
22. Moran, G. R., & Entsch, B. (1995) Protein Expression Purif. 6, 164-168.
23. Palfey, B. A., Entsch, B., Ballou, D. P., & Massey, V. (1994) Biochemistry 33, 1545-1554.
24. Rossman, M. G., Moras, D., & Olsen, K. W. (1974) Nature 250, 194-199.
25. Schreuder, H. A., Prick, P. A. J., Wierenga, R. K., Vriend, G., Wilson, K. S., Hoi, W. G. J., & Drenth, J. (1989) J. Mol Biol. 208, 679-696.
26. Schreuder, H. A., van der Laan, J. M., Swarte, M. B. A., Kalk, K. H., Hoi, W. G. J., & Drenth, J. (1992) Proteins: Struct., Funct., Genet. 14, 178-190.
27. Schreuder, H. A., Mattevi, A., Obmolova, G., Kalk, K. H., Hol, W. G. J., van der Bolt, F. J. T., & van Berkel, W. J. H. (1994) Biochemistry. 33, 10161-10170.
28. Shoun, H., Arima, K., & Beppu, T. (1983) J. Biochem. 93, 169-176.
29. Shuman, B., & Dix, T. A. (1993) J. Biol. Chem. 268, 17057-17062.
30. Spector, T., & Massey, V. (1972) J. Biol. Chem. 247, 4679-4687.
31. Van Berkel, W., Westphal, A., Eschrich, K., Eppink, M., & De Kok, A. (1992) Eur. J. Biochem. 210, 411-419.
32. Van Berkel, W. J. H., Eppink, M. H. M., & Schreuder, H. A. (1994a) Protein Sci. 3, 2245-2253.
33. Van Berkel, W. J. H., van der Bolt, F. J. T., Eppink, M., De Kok, A., Rietjens, I. M. C. M., Veeger, C., Vervoort, J., & Schreuder, H. A. (1994b) in Flavins and Flavoproteins 1993 (Yagi, K., Ed.) pp 231-234, de Gruyter, Berlin.
34. Weijer, W. J., Hofsteenge, J., Beintema, J. J., Wierenga, R. K., & Drenth, J. (1983) Eur. J. Biochem. 133, 109-118.
35. Wierenga, R. K., de Jong, R. J., Kalk, K. H., Hol, W. G. J., & Drenth, J. (1979) J. Mol. Biol. 131, 55-73.
36. Wong, C. M., Dilworth, M. J., & Glenn, A. R. (1994) Microbiology 140, 2775-2786.