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Volumn 19, Issue 17, 2013, Pages 4879-4888

A 26-gene hypoxia signature predicts benefit from hypoxia-modifying therapy in laryngeal cancer but not bladder cancer

Author keywords

[No Author keywords available]

Indexed keywords

CARBOGEN; COMPLEMENTARY DNA; NICOTINAMIDE; RNA;

EID: 84883470111     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-13-0542     Document Type: Article
Times cited : (197)

References (38)
  • 1
    • 0032708195 scopus 로고    scopus 로고
    • Oxygenation of head and neck cancer: Changes during radiotherapy and impact on treatment outcome
    • Brizel DM, Dodge RK, Clough RW, Dewhirst MW. Oxygenation of head and neck cancer: changes during radiotherapy and impact on treatment outcome. Radiother Oncol 1999;53:113-7.
    • (1999) Radiother Oncol , vol.53 , pp. 113-117
    • Brizel, D.M.1    Dodge, R.K.2    Clough, R.W.3    Dewhirst, M.W.4
  • 3
    • 79960344338 scopus 로고    scopus 로고
    • Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck - A systematic review and meta-analysis
    • Overgaard J. Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck - a systematic review and meta-analysis. Radiother Oncol 2011;100:22-32.
    • (2011) Radiother Oncol , vol.100 , pp. 22-32
    • Overgaard, J.1
  • 4
    • 84864003904 scopus 로고    scopus 로고
    • Accelerated radiotherapy with carbogen and nicotinamide for laryngeal cancer: Results of a phase III randomized trial
    • Janssens GO, Rademakers SE, Terhaard CH, Doornaert PA, Bijl HP, van den Ende P, et al. Accelerated radiotherapy with carbogen and nicotinamide for laryngeal cancer: results of a phase III randomized trial. J Clin Oncol 2012;30:1777-83.
    • (2012) J Clin Oncol , vol.30 , pp. 1777-1783
    • Janssens, G.O.1    Rademakers, S.E.2    Terhaard, C.H.3    Doornaert, P.A.4    Bijl, H.P.5    Van Den Ende, P.6
  • 5
    • 26444467146 scopus 로고    scopus 로고
    • Plasma osteopontin, hypoxia, and response to the hypoxia sensitiser nimorazole in radiotherapy of head and neck cancer: Results from the DAHANCA 5 randomised double-blind placebo-controlled trial
    • DOI 10.1016/S1470-2045(05)70292-8, PII S1470204505702928
    • Overgaard J, Eriksen JG, Nordsmark M, Alsner J, Horsman MR. Plasma osteopontin, hypoxia, and response to the hypoxia sensitiser nimorazole in radiotherapy of head and neck cancer: results from the DAHANCA 5 randomised double-blind placebo-controlled trial. Lancet Oncol 2005;6:757-64. (Pubitemid 41430716)
    • (2005) Lancet Oncology , vol.6 , Issue.10 , pp. 757-764
    • Overgaard, J.1    Eriksen, J.G.2    Nordsmark, M.3    Alsner, J.4    Horsman, M.R.5
  • 7
    • 33646454133 scopus 로고    scopus 로고
    • 18F]-misonidazole positron emission tomography-detected tumor hypoxia in patients with advanced head and neck cancer randomly assigned to chemoradiation with or without tirapazamine: A substudy of Trans-Tasman Radiation Oncology Group study 98.02
    • DOI 10.1200/JCO.2005.05.2878
    • Rischin D, Hicks RJ, Fisher R, Binns D, Corry J, Porceddu S, et al. Prognostic significance of [18F]-misonidazole positron emission tomography-detected tumor hypoxia in patients with advanced head and neck cancer randomly assigned to chemoradiation with or without tirapazamine: a substudy of Trans-Tasman Radiation Oncology Group Study 98.02. J Clin Oncol 2006;24:2098-104. (Pubitemid 46622121)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.13 , pp. 2098-2104
    • Rischin, D.1    Hicks, R.J.2    Fisher, R.3    Binns, D.4    Corry, J.5    Porceddu, S.6    Peters, L.J.7
  • 8
    • 80051794223 scopus 로고    scopus 로고
    • Development of a hypoxia gene expression classifier with predictive impact for hypoxic modification of radiotherapy in head and neck cancer
    • Toustrup K, Sorensen BS, Nordsmark M, Busk M, Wiuf C, Alsner J, et al. Development of a hypoxia gene expression classifier with predictive impact for hypoxic modification of radiotherapy in head and neck cancer. Cancer Res 2011;71:5923-31.
    • (2011) Cancer Res , vol.71 , pp. 5923-5931
    • Toustrup, K.1    Sorensen, B.S.2    Nordsmark, M.3    Busk, M.4    Wiuf, C.5    Alsner, J.6
  • 9
    • 79951938429 scopus 로고    scopus 로고
    • Radiotherapy with concurrent carbogen and nicotinamide in bladder carcinoma
    • Hoskin PJ, Rojas AM, Bentzen SM, Saunders MI. Radiotherapy with concurrent carbogen and nicotinamide in bladder carcinoma. J Clin Oncol 2010;28:4912-8.
    • (2010) J Clin Oncol , vol.28 , pp. 4912-4918
    • Hoskin, P.J.1    Rojas, A.M.2    Bentzen, S.M.3    Saunders, M.I.4
  • 10
    • 84885382291 scopus 로고    scopus 로고
    • Necrosis predicts benefit from hypoxia-modifying therapy in high risk bladder cancer
    • Eustace A, Irlam JJ, Taylor J, Denley H, Agrawal S, Choudhury A, et al. Necrosis predicts benefit from hypoxia-modifying therapy in high risk bladder cancer. Radiother Oncol 2013;S0167-8140:00232-6.
    • (2013) Radiother Oncol , vol.S0167-8140 , pp. 00232-00236
    • Eustace, A.1    Irlam, J.J.2    Taylor, J.3    Denley, H.4    Agrawal, S.5    Choudhury, A.6
  • 11
    • 0029955072 scopus 로고    scopus 로고
    • Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck
    • DOI 10.1016/S0167-8140(96)91811-3, PII S0167814096018117
    • Nordsmark M, Overgaard M, Overgaard J. Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck. Radiother Oncol 1996;41:31-9. (Pubitemid 26396294)
    • (1996) Radiotherapy and Oncology , vol.41 , Issue.1 , pp. 31-39
    • Nordsmark, M.1    Overgaard, M.2    Overgaard, J.3
  • 12
    • 84868367617 scopus 로고    scopus 로고
    • FAZA PET/CT hypoxia imaging in patients with squamous cell carcinoma of the head and neck treated with radiotherapy: Results from the DAHANCA 24 trial
    • Mortensen LS, Johansen J, Kallehauge J, Primdahl H, Busk M, Lassen P, et al. FAZA PET/CT hypoxia imaging in patients with squamous cell carcinoma of the head and neck treated with radiotherapy: results from the DAHANCA 24 trial. Radiother Oncol 2012;105:14-20.
    • (2012) Radiother Oncol , vol.105 , pp. 14-20
    • Mortensen, L.S.1    Johansen, J.2    Kallehauge, J.3    Primdahl, H.4    Busk, M.5    Lassen, P.6
  • 13
    • 70350097618 scopus 로고    scopus 로고
    • Hypoxia in larynx carcinomas assessed by pimonidazole binding and the value of CA-IX and vascularity as surrogate markers of hypoxia
    • Hoogsteen IJ, Lok J, Marres HA, Takes RP, Rijken PF, van der Kogel AJ, et al. Hypoxia in larynx carcinomas assessed by pimonidazole binding and the value of CA-IX and vascularity as surrogate markers of hypoxia. Eur J Cancer 2009;45:2906-14.
    • (2009) Eur J Cancer , vol.45 , pp. 2906-2914
    • Hoogsteen, I.J.1    Lok, J.2    Marres, H.A.3    Takes, R.P.4    Rijken, P.F.5    Van Der Kogel, A.J.6
  • 14
    • 49549103347 scopus 로고    scopus 로고
    • Overexpression of intrinsic hypoxia markers HIF1alpha and CA-IX predict for local recurrence in stage T1-T2 glottic laryngeal carcinoma treated with radiotherapy
    • Schrijvers ML, van der Laan BF, de Bock GH, Pattje WJ, Mastik MF, Menkema L, et al. Overexpression of intrinsic hypoxia markers HIF1alpha and CA-IX predict for local recurrence in stage T1-T2 glottic laryngeal carcinoma treated with radiotherapy. Int J Radiat Oncol Biol Phys 2008;72:161-9.
    • (2008) Int J Radiat Oncol Biol Phys , vol.72 , pp. 161-169
    • Schrijvers, M.L.1    Van Der Laan, B.F.2    De Bock, G.H.3    Pattje, W.J.4    Mastik, M.F.5    Menkema, L.6
  • 16
    • 34250182435 scopus 로고    scopus 로고
    • Lack of prognostic and predictive value of CA IX in radiotherapy of squamous cell carcinoma of the head and neck with known modifiable hypoxia: An evaluation of the DAHANCA 5 study
    • DOI 10.1016/j.radonc.2007.05.009, PII S0167814007002150, Highlights from the 10th International ESTRO-Wolfsberg Meeting on Molecular Radiation Biology/Oncology 2007
    • Eriksen JG, Overgaard J. Lack of prognostic and predictive value of CA IX in radiotherapy of squamous cell carcinoma of the head and neck with known modifiable hypoxia: an evaluation of the DAHANCA 5 study. Radiother Oncol 2007;83:383-8. (Pubitemid 46907987)
    • (2007) Radiotherapy and Oncology , vol.83 , Issue.3 , pp. 383-388
    • Eriksen, J.G.1    Overgaard, J.2
  • 17
    • 0035300410 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor-1alpha: A novel predictive and prognostic parameter in the radiotherapy of oropharyngeal cancer
    • Aebersold DM, Burri P, Beer KT, Laissue J, Djonov V, Greiner RH, et al. Expression of hypoxia-inducible factor-1alpha: a novel predictive and prognostic parameter in the radiotherapy of oropharyngeal cancer. Cancer Res 2001;61:2911-6. (Pubitemid 32691934)
    • (2001) Cancer Research , vol.61 , Issue.7 , pp. 2911-2916
    • Aebersold, D.M.1    Burri, P.2    Beer, K.T.3    Laissue, J.4    Djonov, V.5    Greiner, R.H.6    Semenza, G.L.7
  • 18
    • 33644819081 scopus 로고    scopus 로고
    • Expression of HIF-1alpha and Glut-1 in human bladder cancer
    • Palit V, Phillips RM, Puri R, Shah T, Bibby MC. Expression of HIF-1alpha and Glut-1 in human bladder cancer. Oncol Rep 2005;14:909-13.
    • (2005) Oncol Rep , vol.14 , pp. 909-913
    • Palit, V.1    Phillips, R.M.2    Puri, R.3    Shah, T.4    Bibby, M.C.5
  • 20
    • 75649117850 scopus 로고    scopus 로고
    • Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene
    • Buffa FM, Harris AL, West CM, Miller CJ. Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene. Br J Cancer 2010;102:428-35.
    • (2010) Br J Cancer , vol.102 , pp. 428-435
    • Buffa, F.M.1    Harris, A.L.2    West, C.M.3    Miller, C.J.4
  • 21
    • 84871446863 scopus 로고    scopus 로고
    • Prospective technical validation and assessment of intra-tumour heterogeneity of a low density array hypoxia gene profile in head and neck squamous cell carcinoma
    • Betts GN, Eustace A, Patiar S, Valentine HR, Irlam J, Ramachandran A, et al. Prospective technical validation and assessment of intra-tumour heterogeneity of a low density array hypoxia gene profile in head and neck squamous cell carcinoma. Eur J Cancer 2013;49:156-65.
    • (2013) Eur J Cancer , vol.49 , pp. 156-165
    • Betts, G.N.1    Eustace, A.2    Patiar, S.3    Valentine, H.R.4    Irlam, J.5    Ramachandran, A.6
  • 23
    • 79952422386 scopus 로고    scopus 로고
    • Predictors of outcome of non-muscle-invasive and muscle-invasive bladder cancer
    • Youssef RF, Lotan Y. Predictors of outcome of non-muscle-invasive and muscle-invasive bladder cancer. Sci World J 2011;11:369-81.
    • (2011) Sci World J , vol.11 , pp. 369-381
    • Youssef, R.F.1    Lotan, Y.2
  • 24
    • 0035710746 scopus 로고    scopus 로고
    • -DeltaDeltaCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001;25:402-8. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 25
    • 84883467727 scopus 로고    scopus 로고
    • Tweedie: Tweedie exponential family models
    • version 2.1.5
    • Dunn PK. Tweedie: Tweedie exponential family models. R package version 2.1.5; 2007.
    • (2007) R Package
    • Dunn, P.K.1
  • 26
    • 0242298213 scopus 로고    scopus 로고
    • GLUT1 and CAIX as intrinsic markers of hypoxia in bladder cancer: Relationship with vascularity and proliferation as predictors of outcome of ARCON
    • DOI 10.1038/sj.bjc.6601260
    • Hoskin PJ, Sibtain A, Daley FM, Wilson GD. GLUT1 and CAIX as intrinsic markers of hypoxia in bladder cancer: relationship with vascularity and proliferation as predictors of outcome of ARCON. Br J Cancer 2003;89:1290-7. (Pubitemid 37363419)
    • (2003) British Journal of Cancer , vol.89 , Issue.7 , pp. 1290-1297
    • Hoskin, P.J.1    Sibtain, A.2    Daley, F.M.3    Wilson, G.D.4
  • 27
    • 84871446863 scopus 로고    scopus 로고
    • Prospective technical validation and assessment of intra-tumour heterogeneity of a low density array hypoxia gene profile in head and neck squamous cell carcinoma
    • Betts GN, Eustace A, Patiar S, Valentine HR, Irlam J, Ramachandran A, et al. Prospective technical validation and assessment of intra-tumour heterogeneity of a low density array hypoxia gene profile in head and neck squamous cell carcinoma. Eur J Cancer 2013;49:156-65.
    • (2013) Eur J Cancer , vol.49 , pp. 156-165
    • Betts, G.N.1    Eustace, A.2    Patiar, S.3    Valentine, H.R.4    Irlam, J.5    Ramachandran, A.6
  • 29
    • 69049111041 scopus 로고    scopus 로고
    • An integrative genomics approach identifies hypoxia inducible factor-1 (HIF-1)-target genes that form the core response to hypoxia
    • Benita Y, Kikuchi H, Smith AD, Zhang MQ, Chung DC, Xavier RJ. An integrative genomics approach identifies hypoxia inducible factor-1 (HIF-1)-target genes that form the core response to hypoxia. Nucleic Acids Res 2009;37:4587-602.
    • (2009) Nucleic Acids Res , vol.37 , pp. 4587-4602
    • Benita, Y.1    Kikuchi, H.2    Smith, A.D.3    Zhang, M.Q.4    Chung, D.C.5    Xavier, R.J.6
  • 30
    • 33644551073 scopus 로고    scopus 로고
    • Gene expression programs in response to hypoxia: Cell type specificity and prognostic significance in human cancers
    • Chi JT, Wang Z, Nuyten DS, Rodriguez EH, Schaner ME, Salim A, et al. Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers. PLoS Med 2006;3:e47.
    • (2006) PLoS Med , vol.3
    • Chi, J.T.1    Wang, Z.2    Nuyten, D.S.3    Rodriguez, E.H.4    Schaner, M.E.5    Salim, A.6
  • 31
    • 70450223507 scopus 로고    scopus 로고
    • Generating specificity and diversity in the transcriptional response to hypoxia
    • Lendahl U, Lee KL, Yang H, Poellinger L. Generating specificity and diversity in the transcriptional response to hypoxia. Nat Rev Genet 2009;10:821-32.
    • (2009) Nat Rev Genet , vol.10 , pp. 821-832
    • Lendahl, U.1    Lee, K.L.2    Yang, H.3    Poellinger, L.4
  • 33
    • 73249140371 scopus 로고    scopus 로고
    • Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: A retrospective analysis of a randomised trial
    • Albain KS, Barlow WE, Shak S, Hortobagyi GN, Livingston RB, Yeh IT, et al. Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial. Lancet Oncol 2010;11:55-65.
    • (2010) Lancet Oncol , vol.11 , pp. 55-65
    • Albain, K.S.1    Barlow, W.E.2    Shak, S.3    Hortobagyi, G.N.4    Livingston, R.B.5    Yeh, I.T.6
  • 36
    • 67549125238 scopus 로고    scopus 로고
    • Gene expression profiling of the tumor microenvironment during breast cancer progression
    • Ma XJ, Dahiya S, Richardson E, Erlander M, Sgroi DC. Gene expression profiling of the tumor microenvironment during breast cancer progression. Breast Cancer Res 2009;11:R7.
    • (2009) Breast Cancer Res , vol.11
    • Ma, X.J.1    Dahiya, S.2    Richardson, E.3    Erlander, M.4    Sgroi, D.C.5
  • 37
    • 80052725362 scopus 로고    scopus 로고
    • Oncotype DX tumor gene expression profiling in stage II colon cancer. Application: Prognostic, risk prediction
    • Webber EM, Lin JS, Evelyn PW. Oncotype DX tumor gene expression profiling in stage II colon cancer. Application: prognostic, risk prediction. PLoS Curr 2010;2:RRN1177.
    • (2010) PLoS Curr , vol.2
    • Webber, E.M.1    Lin, J.S.2    Evelyn, P.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.