Comprehensive chromosome screening alters traditional morphology-based embryo selection: A prospective study of 100 consecutive cycles of planned fresh euploid blastocyst transfer

Fertility and Sterility

Volumn 100, Issue 3, 2013, Pages 718-724

  Forman, Eric J ^a,b   Upham, Kathleen M ^a   Cheng, Michael ^a   Zhao, Tian ^a   Hong, Kathleen H ^a,b   Treff, Nathan R ^a,b   Scott, Richard T ^a,b  

^a REPRODUCTIVE MEDICINE ASSOCIATES OF NEW JERSEY   (United States)

^b ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

aneuploidy; comprehensive chromosome screening; eSET; preimplantation genetic screening; Single embryo transfer

Indexed keywords

ADULT; ANEUPLOIDY; ARTICLE; BLASTOCYST; CHROMOSOME; CONTROLLED STUDY; EMBRYO; EMBRYO TRANSFER; FEMALE; GENETIC SCREENING; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROSPECTIVE STUDY;

EID: 84883460800     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2013.04.043     Document Type: Article

References (40)

1. S. Mastenbroek, M. Twisk, F. van der Veen, and S. Repping Preimplantation genetic screening: a systematic review and meta-analysis of RCTs Hum Reprod Update 17 2011 454 466
2. Practice Committee of the American Society for Reproductive Medicine Multiple gestation associated with infertility therapy: an American Society for Reproductive Medicine Practice Committee opinion Fertil Steril 97 2012 825 834
3. C. Staessen, W. Verpoest, P. Donoso, P. Haentjens, J. van der Elst, and I. Liebaers Preimplantation genetic screening does not improve delivery rate in women under the age of 36 following single-embryo transfer Hum Reprod 23 2008 2818 2825
4. R.P. Jansen, M.C. Bowman, K.A. de Boer, D.A. Leigh, D.B. Lieberman, and S.J. McArthur What next for preimplantation genetic screening (PGS)? Experience with blastocyst biopsy and testing for aneuploidy Hum Reprod 23 2008 1476 1478
5. E.J. Forman, X. Tao, K.M. Ferry, D. Taylor, N.R. Treff, and R.T. Scott Jr. Single embryo transfer with comprehensive chromosome screening results in improved ongoing pregnancy rates and decreased miscarriage rates Hum Reprod 27 2012 1217 1222
6. Z. Yang, J. Liu, G.S. Collins, S.A. Salem, X. Liu, and S.S. Lyle Selection of single blastocysts for fresh transfer via standard morphology assessment alone and with array CGH for good prognosis IVF patients: results from a randomized pilot study Mol Cytogen 5 2012 24
7. Forman EJ, Hong KH, Ferry KM, Tao X, Taylor D, Levy B, et al. In vitro fertilization with single euploid blastocyst transfer: a randomized controlled trial. Fertil Steril. [Epub ahead of print].
8. J.D. Kresowik, A.E. Sparks, and B.J. van Voorhis Clinical factors associated with live birth after single embryo transfer Fertil Steril 98 2012 1152 1156
9. D.K. Gardner, and W.B. Schoolcraft In vitro culture of human blastocysts R. Jansen, D. Mortimer, Toward reproductive certainty: infertility and genetics beyond 1999 Parthenon Press Carnforth 378 388
10. B.S. Shapiro, S.T. Daneshmand, H. Restrepo, F.C. Garner, M. Aguirre, and C. Hudson Matched-cohort comparison of single-embryo transfers in fresh and frozen-thawed embryo transfer cycles Fertil Steril 99 2013 389 392
11. B.S. Shapiro, K.S. Richter, D.C. Harris, and S.T. Daneshmand A comparison of day 5 and day 6 blastocyst transfers Fertil Steril 75 2001 1126 1130
12. N.R. Treff, X. Tao, K.M. Ferry, J. Su, D. Taylor, and R.T. Scott Jr. Development and validation of an accurate quantitative real-time polymerase chain reaction-based assay for human blastocyst comprehensive chromosomal aneuploidy screening Fertil Steril 97 2012 819 824
13. R.T. Scott Jr., K. Ferry, J. Su, X. Tao, K. Scott, and N.R. Treff Comprehensive chromosome screening is highly predictive of the reproductive potential of human embryos: a prospective, blinded, nonselection study Fertil Steril 97 2012 870 875
14. R.T. Scott Jr., X. Tao, D. Taylor, K. Ferry, and N. Treff A prospective randomized controlled trial demonstrating significantly increased clinical pregnancy rates following 24 chromosome aneuploidy screening: biopsy and analysis on day 5 with fresh transfer Fertil Steril 94 2010 S2
15. Centers for Disease Control and Prevention, American Society for Reproductive Medicine, Society for Assisted Reproductive Technology. 2009 Assisted Reproductive Technology Success Rates: National Summary and Fertility Clinic Reports. Atlanta: U.S. Department of Health and Human Services; 2011.
16. Z. Pandian, S. Bhattacharya, O. Ozturk, G. Serour, and A. Templeton Number of embryos for transfer following in-vitro fertilisation or intra-cytoplasmic sperm injection Cochrane Database Syst Rev 2009 CD003416
17. W.B. Schoolcraft, N.R. Treff, J.M. Stevens, K. Ferry, M. Katz-Jaffe, and R.T. Scott Jr. Live birth outcome with trophectoderm biopsy, blastocyst vitrification, and single-nucleotide polymorphism microarray-based comprehensive chromosome screening in infertile patients Fertil Steril 96 2011 638 640
18. M. Niinimaki, A.M. Suikkari, S. Makinen, V. Soderstrom-Anttila, and H. Martikainen Elective single-embryo transfer in women aged 40-44 years Hum Reprod 28 2013 331 335
19. N. Gleicher The irrational attraction of elective single-embryo transfer (eSET) Hum Reprod 28 2013 294 297
20. A. Sazonova, K. Kallen, A. Thurin-Kjellberg, U.B. Wennerholm, and C. Bergh Neonatal and maternal outcomes comparing women undergoing two in vitro fertilization (IVF) singleton pregnancies and women undergoing one IVF twin pregnancy Fertil Steril 99 2012 731 737
21. E.S. Jungheim, G.L. Ryan, E.D. Levens, A.F. Cunningham, G.A. Macones, and K.R. Carson Embryo transfer practices in the United States: a survey of clinics registered with the Society for Assisted Reproductive Technology Fertil Steril 94 2010 1432 1436
22. L.A. Pasch, S.E. Gregorich, P.K. Katz, S.G. Millstein, R.D. Nachtigall, and M.E. Bleil Psychological distress and in vitro fertilization outcome Fertil Steril 98 2012 459 464
23. S. Assou, D. Haouzi, J. de Vos, and S. Hamamah Human cumulus cells as biomarkers for embryo and pregnancy outcomes Mol Hum Reprod 16 2010 531 538
24. L.J. McKenzie, S.A. Pangas, S.A. Carson, E. Kovanci, P. Cisneros, and J.E. Buster Human cumulus granulosa cell gene expression: a predictor of fertilization and embryo selection in women undergoing IVF Hum Reprod 19 2004 2869 2874
25. R.A. Anderson, R. Sciorio, H. Kinnell, R.A. Bayne, K.J. Thong, and P.A. de Sousa Cumulus gene expression as a predictor of human oocyte fertilisation, embryo development and competence to establish a pregnancy Reproduction 138 2009 629 637
26. M.G. Katz-Jaffe, S. McReynolds, D.K. Gardner, and W.B. Schoolcraft The role of proteomics in defining the human embryonic secretome Mol Hum Reprod 15 2009 271 277
27. F. Dominguez, B. Gadea, F.J. Esteban, J.A. Horcajadas, A. Pellicer, and C. Simon Comparative protein-profile analysis of implanted versus non-implanted human blastocysts Hum Reprod 23 2008 1993 2000
28. R. Scott, E. Seli, K. Miller, D. Sakkas, K. Scott, and D.H. Burns Noninvasive metabolomic profiling of human embryo culture media using Raman spectroscopy predicts embryonic reproductive potential: a prospective blinded pilot study Fertil Steril 90 2008 77 83
29. E. Seli, C.G. Vergouw, H. Morita, L. Botros, P. Roos, and C.B. Lambalk Noninvasive metabolomic profiling as an adjunct to morphology for noninvasive embryo assessment in women undergoing single embryo transfer Fertil Steril 94 2010 535 542
30. D.K. Gardner, P.L. Wale, R. Collins, and M. Lane Glucose consumption of single post-compaction human embryos is predictive of embryo sex and live birth outcome Hum Reprod 26 2011 1981 1986
31. C. Wong, A.A. Chen, B. Behr, and S. Shen Time-lapse microscopy and image analysis in basic and clinical embryo development research Reprod Biomed Online 26 2013 120 129
32. M. Meseguer, I. Rubio, M. Cruz, N. Basile, J. Marcos, and A. Requena Embryo incubation and selection in a time-lapse monitoring system improves pregnancy outcome compared with a standard incubator: a retrospective cohort study Fertil Steril 98 2012 1481 1489.e10
33. K.S. Richter, S.K. Shipley, I. McVearry, M.J. Tucker, and E.A. Widra Cryopreserved embryo transfers suggest that endometrial receptivity may contribute to reduced success rates of later developing embryos Fertil Steril 86 2006 862 866
34. N.R. Treff, J. Su, X. Tao, B. Levy, and R.T. Scott Jr. Accurate single cell 24 chromosome aneuploidy screening using whole genome amplification and single nucleotide polymorphism microarrays Fertil Steril 94 2010 2017 2021
35. M.J. Davies, V.M. Moore, K.J. Willson, P. van Essen, K. Priest, and H. Scott Reproductive technologies and the risk of birth defects N Engl J Med 366 2012 1803 1813
36. S. Desmyttere, M. de Rycke, C. Staessen, I. Liebaers, F. de Schrijver, and W. Verpoest Neonatal follow-up of 995 consecutively born children after embryo biopsy for PGD Hum Reprod 27 2012 288 293
37. R.T. Scott Jr, K.M. Ferry, E.J Forman, T. Zhao, and N.R. Treff Cleavage stage biopsy significantly impairs human embryonic implantation potential while blastocyst biopsy does not: a randomized and paired clinical trial Fertil Steril 2013 May 28 10.1016/j.fertnstert.2013.04.039
38. W.P. Martins, I.A. Rocha, R.A. Ferriani, and C.O. Nastri Assisted hatching of human embryos: a systematic review and meta-analysis of randomized controlled trials Hum Reprod Update 17 2011 438 453
39. L.A. Schieve, S.F. Meikle, H.B. Peterson, G. Jeng, N.M. Burnett, and L.S. Wilcox Does assisted hatching pose a risk for monozygotic twinning in pregnancies conceived through in vitro fertilization? Fertil Steril 74 2000 288 294
40. J. Knopman, L.C. Krey, J. Lee, M.E. Fino, A.P. Novetsky, and N. Noyes Monozygotic twinning: an eight-year experience at a large IVF center Fertil Steril 94 2010 502 510