The journey of the organelle: Teamwork and regulation in intracellular transport

Current Opinion in Cell Biology

Volumn 25, Issue 4, 2013, Pages 483-488

  Barlan, Kari ^a   Rossow, Molly J ^a   Gelfand, Vladimir I ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHALASIN; FAT DROPLET; KINESIN 1; MOLECULAR MOTOR; MYOSIN V;

ACTIN FILAMENT; CELL FUNCTION; CELL MEMBRANE; CELL ORGANELLE; CYTOPLASM; CYTOSKELETON; ENDOPLASMIC RETICULUM; ENZYME ACTIVE SITE; EUKARYOTIC CELL; GOLGI COMPLEX; INTRACELLULAR TRANSPORT; MEMBRANE FUSION; MEMBRANE VESICLE; MICROTUBULE; MITOCHONDRION; MOTOR ACTIVITY; NERVE FIBER; NONHUMAN; OPTICAL TWEEZERS; PRIORITY JOURNAL; REVIEW; SACCHAROMYCES CEREVISIAE; SECRETORY VESICLE;

ANIMALS; BIOLOGICAL TRANSPORT; CYTOSKELETON; EUKARYOTIC CELLS; MOLECULAR MOTOR PROTEINS; ORGANELLES;

EUKARYOTA;

EID: 84883459873     PISSN: 09550674     EISSN: 18790410     Source Type: Journal    
DOI: 10.1016/j.ceb.2013.02.018     Document Type: Review

References (33)

1. Rai A.K., Rai A., Ramaiya A.J., Jha R., Mallik R. Molecular adaptations in dynein to generate large collective forces inside cells. Cell 2013, 152:172-182.
2. Hendricks A.G., Holzbaur E.L.F., Goldman Y.E. Force measurements on cargoes in living cells reveal collective dynamics of microtubule motors. Proc Natl Acad Sci U S A 2012, 10.1073/pnas.1215462109.
3. Blehm B.H., Schroer T.A., Trybus K.M., Chemla Y.R., Selvin P.R. In vivo optical trapping indicates kinesin's stall force is reduced by dynein during intracellular transport. Proc Natl Acad Sci U S A 2013, 10.1073/pnas.1219961110.
4. Driver J.W., Jamison D.K., Uppulury K., Rogers A.R., Kolomeisky A.B., Diehl M.R. Productive cooperation among processive motors depends inversely on their mechanochemical efficiency. Biophys J 2011, 101:386-395.
5. Jamison D.K., Driver J.W., Diehl M.R. Cooperative responses of multiple kinesins to variable and constant loads. J Biol Chem 2012, 287:3357-3365.
6. Reis G.F., Yang G., Szpankowski L., Weaver C., Shah S.B., Robinson J.T., Hays T.S., Danuser G., Goldstein L.S.B. Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila. Mol Biol Cell 2012, 23:1700-1714.
7. Derr N.D., Goodman B.S., Jungmann R., Leschziner A.E., Shih W.M., Reck-Peterson S.L. Tug-of-war in motor protein ensembles revealed with a programmable DNA origami scaffold. Science 2012, 10.1126/science.1226734.
8. Hendricks A.G., Perlson E., Ross J.L., Schroeder H.W., Tokito M., Holzbaur E.L.F. Motor coordination via a tug-of-war mechanism drives bidirectional vesicle transport. Curr Biol 2010, 20:697-702.
9. Ally S., Larson A.G., Barlan K., Rice S.E., Gelfand V.I. Opposite-polarity motors activate one another to trigger cargo transport in live cells. J Cell Biol 2009, 187:1071-1082.
10. Kunwar A., Tripathy S.K., Xu J., Mattson M.K., Anand P., Sigua R., Vershinin M., Mckenney R.J., Yu C.C., Mogilner A., et al. Mechanical stochastic tug-of-war models cannot explain bidirectional lipid-droplet transport. Proc Natl Acad Sci U S A 2011, 108:18960-18965.
11. Leidel C., Longoria R.A., Gutierrez F.M., Shubeita G.T. Measuring molecular motor forces in vivo: implications for tug-of-war models of bidirectional transport. Biophys J 2012, 103:492-500.
12. Donovan K.W., Bretscher A. Myosin-V is activated by binding secretory cargo and released in coordination with Rab/Exocyst FUNCTION. Dev Cell 2012, 23:13.
13. Akhmanova A., Hammer J.A. Linking molecular motors to membrane cargo. Curr Opin Cell Biol 2010, 22:479-487.
14. Yadav S., Puthenveedu M.A., Linstedt A.D. Golgin160 recruits the dynein motor to position the Golgi apparatus. Dev Cell 2012, 23:153-165.
15. Glater E.E., Megeath L.J., Stowers R.S., Schwarz T.L. Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent. J Cell Biol 2006, 173:545-557.
16. 2+-dependent regulation of kinesin-mediated mitochondrial motility. Cell 2009, 136:163-174.
17. Wang X., Winter D., Ashrafi G., Schlehe J., Wong Y.L., Selkoe D., Rice S., Steen J., LaVoie M.J., Schwarz T.L. PINK1 and Parkin Target Miro for phosphorylation and degradation to arrest mitochondrial motility. Cell 2011, 147:893-906.
18. Mckenney R.J., Vershinin M., Kunwar A., Vallee R.B., Gross S.P. LIS1 and NudE induce a persistent dynein force-producing state. Cell 2010, 141:304-314.
19. Huang J., Roberts A.J., Leschziner A.E., Reck-Peterson S.L. Lis1 acts as a "Clutch" between the ATPase and microtubule-binding domains of the dynein motor. Cell 2012, 150:975-986.
20. Egan M.J., Tan K., Reck-Peterson S.L. Lis1 is an initiation factor for dynein-driven organelle transport. J Cell Biol 2012, 10.1083/jcb.201112101.
21. Tang N., Ostap E.M. Motor domain-dependent localization of myo1b (myr-1). Curr Biol 2001, 11:1131-1135.
22. Clayton J.E., Sammons M.R., Stark B.C., Hodges A.R., Lord M. Differential regulation of unconventional fission yeast myosins via the actin track. Curr Biol 2010, 20:1423-1431.
23. Hodges A.R., Krementsova E.B., Bookwalter C.S., Fagnant P.M., Sladewski T.E., Trybus K.M. Tropomyosin is essential for processive movement of a class V myosin from budding yeast. Curr Biol 2012, 22:1410-1416.
24. Reck-Peterson S.L., Tyska M.J., Novick P.J., Mooseker M.S. The yeast class V myosins, Myo2p and Myo4p, are nonprocessive actin-based motors. J Cell Biol 2001, 153:1121-1126.
25. Barlan K., Lu W., Gelfand V.I. The microtubule-binding protein ensconsin is an essential cofactor of kinesin-1. Curr Biol 2013, 10.1016/j.cub.2013.01.008.
26. Schuh M. An actin-dependent mechanism for long-range vesicle transport. Nat Cell Biol 2011, 10.1038/ncb2353.
27. Miller P.M., Folkmann A.W., Maia A.R.R., Efimova N., Efimov A., Kaverina I. Golgi-derived CLASP-dependent microtubules control Golgi organization and polarized trafficking in motile cells. Nat Publ Group 2009, 11:1069-1080.
28. Efimov A., Kharitonov A., Efimova N., Loncarek J., Miller P.M., Andreyeva N., Gleeson P., Galjart N., Maia A.R.R., McLeod I.X. Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network. Dev Cell 2007, 12:917-930.
29. Friedman J.R., Webster B.M., Mastronarde D.N., Verhey K.J., Voeltz G.K. ER sliding dynamics and ER-mitochondrial contacts occur on acetylated microtubules. J Cell Biol 2010, 190:363-375.
30. Friedman J.R., Lackner L.L., West M., DiBenedetto J.R., Nunnari J., Voeltz G.K. ER tubules mark sites of mitochondrial division. Science 2011, 334:358-362.
31. Reed N.A., Cai D., Blasius T.L., Jih G.T., Meyhofer E., Gaertig J., Verhey K.J. Microtubule acetylation promotes kinesin-1 binding and transport. Curr Biol 2006, 16:2166-2172.
32. Cai D., McEwen D.P., Martens J.R., Meyhofer E., Verhey K.J. Single molecule imaging reveals differences in microtubule track selection between kinesin motors. PLoS Biol 2009, 7:e1000216.
33. Fu C., Jain D., Costa J., Velve-Casquillas G., Tran P.T. mmb1p binds mitochondria to dynamic microtubules. Curr Biol 2011, 21:1431-1439.