An endogenously produced fragment of cardiac myosin-binding protein C is pathogenic and can lead to heart failure

Circulation Research

Volumn 113, Issue 5, 2013, Pages 553-561

  Razzaque, Md Abdur ^a   Gupta, Manish ^a   Osinska, Hanna ^a   Gulick, James ^a   Blaxall, Burns C ^a   Robbins, Jeffrey ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

cardiomyopathies; contractile proteins; sarcomeres

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; CARDIAC MYOSIN; MYOSIN BINDING PROTEIN C;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HEART FAILURE; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; SARCOMERE; TRANSGENE; TRANSGENIC MOUSE;

CARDIOMYOPATHIES; CONTRACTILE PROTEINS; SARCOMERES;

ANIMALS; BUTADIENES; CARRIER PROTEINS; FEMALE; FIBROSIS; GENE EXPRESSION REGULATION; HEART FAILURE; HEART VENTRICLES; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, TRANSGENIC; MYOCARDIUM; MYOCYTES, CARDIAC; MYOSIN HEAVY CHAINS; NITRILES; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT FUSION PROTEINS; SARCOMERES;

EID: 84883458676     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.113.301225     Document Type: Article

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