Increased CD14+HLA-DR-/low myeloid-derived suppressor cells correlate with extrathoracic metastasis and poor response to chemotherapy in non-small cell lung cancer patients

Cancer Immunology, Immunotherapy

Volumn 62, Issue 9, 2013, Pages 1439-1451

  Huang, Ang ^a,c   Zhang, Bo ^b   Wang, Bo ^a   Zhang, Fan ^a   Fan, Ke Xing ^a,b   Guo, Ya Jun ^a,b  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c BEIJING 302 HOSPITAL   (China)

Author keywords

HLA DR expression; Immunosuppression; Myeloid derived suppressor cells; Non small cell lung cancer; Tumor immunity

Indexed keywords

ANTINEOPLASTIC AGENT; CD14 ANTIGEN; CD16 ANTIGEN; CD86 ANTIGEN; CISPLATIN; DOCETAXEL; GAMMA INTERFERON; GEMCITABINE; PEMETREXED; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; TUMOR MARKER;

ADULT; ANTIGEN EXPRESSION; ARTICLE; CANCER GROWTH; CANCER PATIENT; CANCER SURVIVAL; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL CONTACT; CELL COUNT; CONTROLLED STUDY; DRUG RESPONSE; DRUG TREATMENT FAILURE; FEMALE; HUMAN; HUMAN CELL; INTERFERON PRODUCTION; LUNG ADENOCARCINOMA; LUNG METASTASIS; LUNG NON SMALL CELL CANCER; LUNG SQUAMOUS CELL CARCINOMA; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MAJOR CLINICAL STUDY; MALE; MONOCYTE; MYELOID DERIVED SUPPRESSOR CELL; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; SUPPRESSOR CELL; T LYMPHOCYTE ACTIVATION; TUMOR IMMUNITY;

ANTIGENS, CD14; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, NON-SMALL-CELL LUNG; CELL GROWTH PROCESSES; CISPLATIN; DEOXYCYTIDINE; DISEASE-FREE SURVIVAL; FEMALE; FLOW CYTOMETRY; GLUTAMATES; GUANINE; HLA-DR ANTIGENS; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; MYELOID CELLS; TAXOIDS;

EID: 84883447186     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-013-1450-6     Document Type: Article

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