-
1
-
-
0031940813
-
SAAM II: Simulation, Analysis and Modeling Software for tracer and pharmacokinetics studies
-
10.1016/S0026-0495(98)90064-6
-
Barrett PH, Bell BM, Cobelli C, Golde H, Schumitzky A, Vicini P, Foster DM (1998) SAAM II: Simulation, Analysis and Modeling Software for tracer and pharmacokinetics studies. Metabolism 147:484-492
-
(1998)
Metabolism
, vol.147
, pp. 484-492
-
-
Barrett, P.H.1
Bell, B.M.2
Cobelli, C.3
Golde, H.4
Schumitzky, A.5
Vicini, P.6
Foster, D.M.7
-
2
-
-
84858335179
-
The designer methcathinone analogs, mephedrone and methylone, are substrates for monoamine transporters in brain tissue
-
22169943 10.1038/npp.2011.304 1:CAS:528:DC%2BC38XktV2qsrc%3D
-
Baumann MH, Ayestas MA Jr, Partilla JS, Sink JR, Shulgin AT, Daley PF, Brandt SD, Rothman RB, Ruoho AE, Cozzi NV (2012) The designer methcathinone analogs, mephedrone and methylone, are substrates for monoamine transporters in brain tissue. Neuropsychopharmacology 37:1192-1203
-
(2012)
Neuropsychopharmacology
, vol.37
, pp. 1192-1203
-
-
Baumann, M.H.1
Ayestas, Jr.M.A.2
Partilla, J.S.3
Sink, J.R.4
Shulgin, A.T.5
Daley, P.F.6
Brandt, S.D.7
Rothman, R.B.8
Ruoho, A.E.9
Cozzi, N.V.10
-
3
-
-
84871923568
-
Psychoactive "bath salts": Not so soothing
-
23178799 10.1016/j.ejphar.2012.11.020 1:CAS:528:DC%2BC38XhvVWisb7P
-
Baumann MH, Partilla JS, Lehner KR (2013) Psychoactive "bath salts": not so soothing. Eur J Pharmacol 698:1-5
-
(2013)
Eur J Pharmacol
, vol.698
, pp. 1-5
-
-
Baumann, M.H.1
Partilla, J.S.2
Lehner, K.R.3
-
4
-
-
84871900847
-
Linking the pharmacological content of ecstasy tablets to the subjective experiences of drug users
-
10.1007/s00213-011-2529-4 1:CAS:528:DC%2BC3MXhtlSgs73O
-
Brunt TM, Koeter MW, Niesink RJ, van den Brink W (2012) Linking the pharmacological content of ecstasy tablets to the subjective experiences of drug users. Psychopharmacology (Berl) 220:751-762
-
(2012)
Psychopharmacology (Berl)
, vol.220
, pp. 751-762
-
-
Brunt, T.M.1
Koeter, M.W.2
Niesink, R.J.3
Van Den Brink, W.4
-
5
-
-
0029916656
-
Disposition of mehylenedioxymethamphetamine and three metabolites in the brains of different rat strains and their possible roles in acute serotonin depletion
-
8602874 10.1016/0006-2952(95)02397-6 1:CAS:528:DyaK28XhslKnurs%3D
-
Chu T, Kumagai Y, DiStefano EW, Cho AK (1996) Disposition of mehylenedioxymethamphetamine and three metabolites in the brains of different rat strains and their possible roles in acute serotonin depletion. Biochem Pharmacol 51:789-796
-
(1996)
Biochem Pharmacol
, vol.51
, pp. 789-796
-
-
Chu, T.1
Kumagai, Y.2
Distefano, E.W.3
Cho, A.K.4
-
6
-
-
0032856963
-
Inhibition of plasma membrane monoamine transporters by betaketoamphetamines
-
10528135 10.1016/S0014-2999(99)00538-5 1:CAS:528:DyaK1MXmvVKitbg%3D
-
Cozzi NV, Sievert MK, Shulgin AT, Jacobill P, Rhuolo AE (1999) Inhibition of plasma membrane monoamine transporters by betaketoamphetamines. Eur J Pharmacol 381:63-69
-
(1999)
Eur J Pharmacol
, vol.381
, pp. 63-69
-
-
Cozzi, N.V.1
Sievert, M.K.2
Shulgin, A.T.3
Jacobill, P.4
Rhuolo, A.E.5
-
7
-
-
33745792813
-
Pharmacokinetic-pharmacodynamic modeling: History and perspectives
-
16404503 10.1007/s10928-005-9002-0 1:CAS:528:DC%2BD28Xms1Oisr8%3D
-
Csajka C, Verotta D (2006) Pharmacokinetic-pharmacodynamic modeling: history and perspectives. J Pharmacokinet Pharmacodyn 33:227-279
-
(2006)
J Pharmacokinet Pharmacodyn
, vol.33
, pp. 227-279
-
-
Csajka, C.1
Verotta, D.2
-
8
-
-
77953870712
-
Multiple-drug toxicity caused by the coadministration of 4-methylmethcathinone (mephedrone) and heroin
-
20406541 10.1093/jat/34.3.162 1:CAS:528:DC%2BC3cXksVOit7o%3D
-
Dickson AJ, Vorce SP, Levine B, Past MR (2010) Multiple-drug toxicity caused by the coadministration of 4-methylmethcathinone (mephedrone) and heroin. J Anal Toxicol 34:162-168
-
(2010)
J Anal Toxicol
, vol.34
, pp. 162-168
-
-
Dickson, A.J.1
Vorce, S.P.2
Levine, B.3
Past, M.R.4
-
9
-
-
70350608139
-
Sprague-Dawley rats display sex-linked differences in the pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA) and its metabolite 3,4-methylenedioxyamphetamine (MDA)
-
19781562 10.1016/j.taap.2009.09.008 1:CAS:528:DC%2BD1MXhtlyrsbrE
-
Fonsart J, Menet MC, Debray M, Hirt D, Noble F, Scherrmann JM, Declèves X (2009) Sprague-Dawley rats display sex-linked differences in the pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA) and its metabolite 3,4-methylenedioxyamphetamine (MDA). Toxicol Appl Pharmacol 241:339-347
-
(2009)
Toxicol Appl Pharmacol
, vol.241
, pp. 339-347
-
-
Fonsart, J.1
Menet, M.C.2
Debray, M.3
Hirt, D.4
Noble, F.5
Scherrmann, J.M.6
Declèves, X.7
-
11
-
-
80054789464
-
4-Methylmethcathinone (mephedrone): Neuropharmacological effects of a designer stimulant of abuse
-
21810934 10.1124/jpet.111.184119 1:CAS:528:DC%2BC3MXhsFehtbrN
-
Hadlock GC, Webb KM, McFadden LM, Chu PW, Ellis JD, Allen SC, Andrenyak DM, Vieira-Brock PL, German CL, Conrad KM, Hoonakker AJ, Gibb JW, Wilkins DG, Hanson GR, Fleckenstein AE (2011) 4-Methylmethcathinone (mephedrone): neuropharmacological effects of a designer stimulant of abuse. J Pharmacol Exp Ther 339:530-536
-
(2011)
J Pharmacol Exp Ther
, vol.339
, pp. 530-536
-
-
Hadlock, G.C.1
Webb, K.M.2
McFadden, L.M.3
Chu, P.W.4
Ellis, J.D.5
Allen, S.C.6
Andrenyak, D.M.7
Vieira-Brock, P.L.8
German, C.L.9
Conrad, K.M.10
Hoonakker, A.J.11
Gibb, J.W.12
Wilkins, D.G.13
Hanson, G.R.14
Fleckenstein, A.E.15
-
12
-
-
33845937770
-
Structure-brain exposure relationships
-
17181137 10.1021/jm060642i 1:CAS:528:DC%2BD28Xht1yrtrnK
-
Hitchcock SA, Pennington LD (2006) Structure-brain exposure relationships. J Med Chem 49:7559-7583
-
(2006)
J Med Chem
, vol.49
, pp. 7559-7583
-
-
Hitchcock, S.A.1
Pennington, L.D.2
-
13
-
-
84856022021
-
2-adrenergic agonist clonidine on the pharmacodynamics and pharmacokinetics of 3,4-methylenedioxymethamphetamine in healthy volunteers
-
22034656 10.1124/jpet.111.188425 1:CAS:528:DC%2BC38XjtVSlt7w%3D
-
2-adrenergic agonist clonidine on the pharmacodynamics and pharmacokinetics of 3,4-methylenedioxymethamphetamine in healthy volunteers. J Pharmacol Exp Ther 340:286-289
-
(2012)
J Pharmacol Exp Ther
, vol.340
, pp. 286-289
-
-
Hysek, C.M.1
Brugger, R.2
Simmler, L.D.3
Bruggisser, M.4
Donzelli, M.5
Grouzmann, E.6
Hoener, M.C.7
Liechti, M.E.8
-
14
-
-
84869096843
-
Elucidation of the phase i and phase II metabolic pathways of (±)-4′-methylmethcathinone (4-MMC) and (±)-4′- (trifluoromethyl)methcathinone (4-TFMMC) in rat liver hepatocytes using LC-MS and LC-MS(2)
-
22985528 10.1016/j.jpba.2012.08.015 1:CAS:528:DC%2BC38Xhs1KlsLbJ
-
Khreit OI, Grant MH, Zhang T, Henderson C, Watson DG, Sutcliffe OB (2013) Elucidation of the phase I and phase II metabolic pathways of (±)-4′-methylmethcathinone (4-MMC) and (±)-4′- (trifluoromethyl)methcathinone (4-TFMMC) in rat liver hepatocytes using LC-MS and LC-MS(2). J Pharm Biomed Anal 72:177-185
-
(2013)
J Pharm Biomed Anal
, vol.72
, pp. 177-185
-
-
Khreit, O.I.1
Grant, M.H.2
Zhang, T.3
Henderson, C.4
Watson, D.G.5
Sutcliffe, O.B.6
-
15
-
-
84865424242
-
Comparative neuropharmacology of three psychostimulant cathinone derivatives: Butylone, mephedrone and methylone
-
22509960 10.1111/j.1476-5381.2012.01998.x
-
López-Arnau R, Martínez-Clemente J, Pubill D, Escubedo E, Camarasa J (2012) Comparative neuropharmacology of three psychostimulant cathinone derivatives: butylone, mephedrone and methylone. Br J Pharmacol 167:407-420
-
(2012)
Br J Pharmacol
, vol.167
, pp. 407-420
-
-
López-Arnau, R.1
Martínez-Clemente, J.2
Pubill, D.3
Escubedo, E.4
Camarasa, J.5
-
17
-
-
79954568293
-
Mephedrone (4-methylmethcathinone)-related deaths
-
21439157 10.1093/anatox/35.3.188 1:CAS:528:DC%2BC3MXjsFCksrs%3D
-
Maskell PD, De Paoli G, Seneviratne C, Pounde DJ (2011) Mephedrone (4-methylmethcathinone)-related deaths. J Anal Toxicol 35:188-191
-
(2011)
J Anal Toxicol
, vol.35
, pp. 188-191
-
-
Maskell, P.D.1
De Paoli, G.2
Seneviratne, C.3
Pounde, D.J.4
-
18
-
-
77953475735
-
Beta-keto amphetamines: Studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography-mass spectrometry
-
20333362 10.1007/s00216-010-3636-5 1:CAS:528:DC%2BC3cXjsleltrc%3D
-
Meyer MR, Wilhelm J, Peters FT, Maurer HH (2010) Beta-keto amphetamines: studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography-mass spectrometry. Anal Bioanal Chem 397:1225-1233
-
(2010)
Anal Bioanal Chem
, vol.397
, pp. 1225-1233
-
-
Meyer, M.R.1
Wilhelm, J.2
Peters, F.T.3
Maurer, H.H.4
-
19
-
-
33847113912
-
The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain
-
17223101 10.1016/j.ejphar.2006.11.075 1:CAS:528:DC%2BD2sXisVWgu7g%3D
-
Nagai F, Nonaka R, Satoh K, Kamimura SHK (2007) The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain. Eur J Pharmacol 559:132-137
-
(2007)
Eur J Pharmacol
, vol.559
, pp. 132-137
-
-
Nagai, F.1
Nonaka, R.2
Satoh, K.3
Kamimura, S.H.K.4
-
20
-
-
0023578486
-
Apparent tolerance to the acute effect of nicotine results in part from distribution kinetics
-
10.1172/JCI113227
-
Porchet HC, Benowitz NL, Sheiner LB, Copelan JR (1987) Apparent tolerance to the acute effect of nicotine results in part from distribution kinetics. J Clin Invest 80:466-741
-
(1987)
J Clin Invest
, vol.80
, pp. 466-741
-
-
Porchet, H.C.1
Benowitz, N.L.2
Sheiner, L.B.3
Copelan, J.R.4
-
21
-
-
0025232386
-
Rats become acutely tolerant to cathine after amphetamine or cathinone administration
-
10.1007/BF02253729 1:CAS:528:DyaK3cXit12lsb8%3D
-
Schechter MD (1990) Rats become acutely tolerant to cathine after amphetamine or cathinone administration. Psychopharmacology (Berl) 101:126-131
-
(1990)
Psychopharmacology (Berl)
, vol.101
, pp. 126-131
-
-
Schechter, M.D.1
-
22
-
-
79953647218
-
Mephedrone (4-methylmethcathinone; 'Meow meow'): Chemical, pharmacological and clinical issues
-
10.1007/s00213-010-2070-x 1:CAS:528:DC%2BC3cXhsVSksb7J
-
Schifano F, Albanese A, Fergus S, Stair JL, Deluca P, Corazza O, Davey Z, Corkery J, Siemann H, Scherbaum N, Farre M, Torrens M, Demetrovics Z, Ghodse AH (2011) Mephedrone (4-methylmethcathinone; 'meow meow'): chemical, pharmacological and clinical issues. Psychopharmacology (Berl) 214:593-602
-
(2011)
Psychopharmacology (Berl)
, vol.214
, pp. 593-602
-
-
Schifano, F.1
Albanese, A.2
Fergus, S.3
Stair, J.L.4
Deluca, P.5
Corazza, O.6
Davey, Z.7
Corkery, J.8
Siemann, H.9
Scherbaum, N.10
Farre, M.11
Torrens, M.12
Demetrovics, Z.13
Ghodse, A.H.14
-
23
-
-
0018394195
-
Simultaneous modeling of pharmacokinetics and pharmacodynamics: Application to d-tubocurarine
-
761446 1:CAS:528:DyaE1MXhsl2qsro%3D
-
Sheiner LB, Stanki DR, Vozeh S, Miller RD, Ham J (1979) Simultaneous modeling of pharmacokinetics and pharmacodynamics: application to d-tubocurarine. Clin Pharmacol Ther 25:358-370
-
(1979)
Clin Pharmacol Ther
, vol.25
, pp. 358-370
-
-
Sheiner, L.B.1
Stanki, D.R.2
Vozeh, S.3
Miller, R.D.4
Ham, J.5
-
24
-
-
84871531590
-
Pharmacological characterization of designer cathinones in vitro
-
22897747 10.1111/j.1476-5381.2012.02145.x 1:CAS:528: DC%2BC3sXitFOmsQ%3D%3D
-
Simmler LD, Buser TA, Donzelli M, Schramm Y, Dieu LH, Huwyler J, Chaboz S, Hoener MC, Liechti ME (2013) Pharmacological characterization of designer cathinones in vitro. Br J Pharmacol 168:458-470
-
(2013)
Br J Pharmacol
, vol.168
, pp. 458-470
-
-
Simmler, L.D.1
Buser, T.A.2
Donzelli, M.3
Schramm, Y.4
Dieu, L.H.5
Huwyler, J.6
Chaboz, S.7
Hoener, M.C.8
Liechti, M.E.9
-
25
-
-
79952898264
-
Determination of cathinones and related ephedrines in forensic whole-blood samples by liquid-chromatography-electrospray tandem mass spectrometry
-
10.1016/j.jchromb.2011.02.010
-
Sørensen LK (2011) Determination of cathinones and related ephedrines in forensic whole-blood samples by liquid-chromatography-electrospray tandem mass spectrometry. J Chromatogr B 879:727-736
-
(2011)
J Chromatogr B
, vol.879
, pp. 727-736
-
-
Sørensen, L.K.1
-
26
-
-
84873988901
-
Comparison of the behavioral and cardiovascular effects of mephedrone with other drugs of abuse in rats
-
10.1007/s00213-012-2855-1 1:CAS:528:DC%2BC38XhtlegsrzJ
-
Varner KJ, Daigle K, Weed PF, Lewis PB, Mahne SE, Sankaranarayanan A, Winsauer PJ (2013) Comparison of the behavioral and cardiovascular effects of mephedrone with other drugs of abuse in rats. Psychopharmacology (Berl) 225:675-685
-
(2013)
Psychopharmacology (Berl)
, vol.225
, pp. 675-685
-
-
Varner, K.J.1
Daigle, K.2
Weed, P.F.3
Lewis, P.B.4
Mahne, S.E.5
Sankaranarayanan, A.6
Winsauer, P.J.7
-
27
-
-
0018853977
-
Intranasal and oral cocaine kinetics
-
7357795 10.1038/clpt.1980.52 1:CAS:528:DyaL3cXhvFWjtr8%3D
-
Wilkinson P, Van Dyke C, Jatlow P, Barash P, Byck (1980) Intranasal and oral cocaine kinetics. Clin Pharmacol Ther 27:386-394
-
(1980)
Clin Pharmacol Ther
, vol.27
, pp. 386-394
-
-
Wilkinson, P.1
Van Dyke, C.2
Jatlow, P.3
Barash, P.4
Byck5
-
28
-
-
79960603129
-
Mephedrone: Use, subjective effects and health risks
-
21592252 10.1111/j.1360-0443.2011.03502.x
-
Winstock A, Mitcheson L, Ramsey J, Davies S, Puchnarewicz M, Marsden J (2011) Mephedrone: use, subjective effects and health risks. Addiction 106:1991-1996
-
(2011)
Addiction
, vol.106
, pp. 1991-1996
-
-
Winstock, A.1
Mitcheson, L.2
Ramsey, J.3
Davies, S.4
Puchnarewicz, M.5
Marsden, J.6
-
29
-
-
78650470484
-
Case series of individuals with analytically confirmed acute mephedrone toxicity
-
10.3109/15563650.2010.531021 1:CAS:528:DC%2BC3cXhsFyrsb7L
-
Wood DM, Davies S, Greene SL, Button J, Holt DW, Ramsey J, Dargan PI (2010a) Case series of individuals with analytically confirmed acute mephedrone toxicity. Clin Toxicol 48:924-927
-
(2010)
Clin Toxicol
, vol.48
, pp. 924-927
-
-
Wood, D.M.1
Davies, S.2
Greene, S.L.3
Button, J.4
Holt, D.W.5
Ramsey, J.6
Dargan, P.I.7
-
30
-
-
77956229460
-
Recreational use of mephedrone (4-methylmethcathinone, 4-MMC) with associated sympathomimetic toxicity
-
20358417 10.1007/s13181-010-0018-5
-
Wood DM, Davies S, Puchnarewicz M, Button J, Archer R, Ovaska H, Ramsey J, Lee T, Holt DW, Dargan PI (2010b) Recreational use of mephedrone (4-methylmethcathinone, 4-MMC) with associated sympathomimetic toxicity. J Med Toxicol 6:327-330
-
(2010)
J Med Toxicol
, vol.6
, pp. 327-330
-
-
Wood, D.M.1
Davies, S.2
Puchnarewicz, M.3
Button, J.4
Archer, R.5
Ovaska, H.6
Ramsey, J.7
Lee, T.8
Holt, D.W.9
Dargan, P.I.10
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