The 5′-untranslated region regulates ATF5 mRNA stability via nonsense-mediated mRNA decay in response to environmental stress

FEBS Journal

Volumn 280, Issue 18, 2013, Pages 4693-4707

  Hatano, Masaya ^a   Umemura, Mariko ^a   Kimura, Natsumi ^a   Yamazaki, Takashi ^a   Takeda, Hitoshi ^a   Nakano, Haruo ^a   Takahashi, Shigeru ^a   Takahashi, Yuji ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

activating transcription factor 5; eIF2 ; nonsense mediated mRNA decay; stress response; transcription factor; translation

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR; ACTIVATING TRANSCRIPTION FACTOR 5; INITIATION FACTOR 2; INITIATION FACTOR 2ALPHA; MESSENGER RNA; UNCLASSIFIED DRUG; AMINO ACID; ATF5 PROTEIN, HUMAN; ISOPROTEIN; PROTEIN KINASE R; RNA BINDING PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; UPF2 PROTEIN, HUMAN; UPF3A PROTEIN, HUMAN;

5' UNTRANSLATED REGION; 5' UNTRANSLATED REGION ALPHA; 5' UNTRANSLATED REGION BETA; ARTICLE; ATF5 GENE; CARCINOMA CELL; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ENVIRONMENTAL STRESS; EXON; GENE CONTROL; GENE EXPRESSION REGULATION; GENE FUNCTION; GENETIC STABILITY; HUMAN; HUMAN CELL; METABOLIC REGULATION; MOLECULAR MECHANICS; NONHUMAN; NONSENSE MEDIATED MRNA DECAY; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; PROTEIN SYNTHESIS; RNA STABILITY; RNA TRANSCRIPTION; RNA TRANSLATION; STRUCTURE ANALYSIS; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION TERMINATION; TRANSLATION REGULATION; UTERINE CERVIX CARCINOMA; ACTIVATING TRANSCRIPTION FACTOR 5; ANIMAL; CYTOLOGY; DRUG ANTAGONISM; EIF2Α; FIBROBLAST; GENETIC TRANSFECTION; GENETICS; HELA CELL; INTRON; METABOLISM; MOUSE; NONSENSE-MEDIATED MRNA DECAY; PHYSIOLOGICAL STRESS; RNA CLEAVAGE; SIGNAL TRANSDUCTION; STRESS; TRANSLATION;

ACTIVATING TRANSCRIPTION FACTOR 5; EIF2Α; NONSENSE-MEDIATED MRNA DECAY; STRESS RESPONSE; TRANSCRIPTION FACTOR; TRANSLATION;

5' UNTRANSLATED REGIONS; ACTIVATING TRANSCRIPTION FACTORS; AMINO ACIDS; ANIMALS; EIF-2 KINASE; EXONS; FIBROBLASTS; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; INTRONS; MICE; OPEN READING FRAMES; PROTEIN ISOFORMS; RNA CLEAVAGE; RNA STABILITY; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 84883424036     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12440     Document Type: Article

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