Salivary cortisol as a biomarker in social science research

Social and Personality Psychology Compass

Volumn 7, Issue 9, 2013, Pages 605-625

  Smyth, Nina ^a   Hucklebridge, Frank ^a   Thorn, Lisa ^a   Evans, Phil ^a   Clow, Angela ^a  

^a UNIVERSITY OF WESTMINSTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84883409832     PISSN: None     EISSN: 17519004     Source Type: Journal    
DOI: 10.1111/spc3.12057     Document Type: Article

References (104)

1. Abercrombie, H. C., Giese-Davis, J., Sephton, S., Epel, E. S., Turner-Cobb, J. M., & Spiegel, D. (2004). Flattened cortisol rhythms in metastatic breast cancer patients. Psychoneuroendocrinology, 29, 1082-1092.
2. Adam, E. K. (2006). Transactions among adolescent trait and state emotion and diurnal and momentary cortisol activity in naturalistic settings. Psychoneuroendocrinology, 31, 664-679.
3. Adam, E. K., & Gunnar, M. R. (2001). Relationship functioning and home and work demands predict individual differences in diurnal cortisol patterns in women. Psychoneuroendocrinology, 26, 189-208.
4. Adam, E. K., & Kumari, M. (2009). Assessing salivary cortisol in large-scale, epidemiological research. Psychoneuroendocrinology, 34, 1423-1436.
5. Adam, E. K., Hawkley, L. C., Kudielka, B. M., & Cacioppo, J. T. (2006). Day-to-day dynamics of experience-cortisol associations in a population-based sample of older adults. Proceedings of the National Academy of Sciences of the United States of America, 103, 17058-17063.
6. Anhoj, J., & Moldrup, C. (2004). Feasibility of collecting diary data from asthma patients through mobile phones and SMS (short message service): Response rate analysis and focus group evaluation from a pilot study. Journal of Medical Internet Research, 6, e42-e42.
7. Badrick, E., Bobak, M., Britton, A., Kirschbaum, C., Marmot, M., & Kumari, M. (2008). The relationship between alcohol consumption and cortisol secretion in an aging cohort. Journal of Clinical Endocrinology and Metabolism, 93, 750-757.
8. Badrick, E., Kirschbaum, C., & Kumari, M. (2007). The relationship between smoking status and cortisol secretion. Journal of Clinical Endocrinology and Metabolism, 92, 819-824.
9. Baxter, J. D., Frohman, L. A., & Felig, P. (1995). Introduction to the endocrine system. In P. Felig, J. D. Baxter & L. A. Frohman (Eds.), Endocrinology and Metabolism (3rd edn., pp. 3-20). New York: McGraw-Hill Inc.
10. Benarroch, E. E. (2011). The melanopsin system phototransduction, projections, functions, and clinical implications. Neurology, 76, 1422-1427.
11. Blackwell, E., Mendes de Leon, C. F., & Miller, G. E. (2006). Applying mixed regression models to the analysis of repeated-measures data in psychosomatic medicine. Psychosomatic Medicine, 68, 870-878.
12. Born, J., Hansen, K., Marshall, L., Molle, M., & Fehm, H. L. (1999). Timing the end of nocturnal sleep. Nature, 397, 29-30.
13. Broderick, J. E., Arnold, D., Kudielka, B. M., & Kirschbaum, C. (2004). Salivary cortisol sampling compliance: Comparison of patients and healthy volunteers. Psychoneuroendocrinology, 29, 636-650.
14. Brooks, K. P., Robles, T. F., & Schetter, C. D. (2011). Adult attachment and cortisol responses to discussions with a romantic partner. Personal Relationships, 18, 302-320.
15. Buske-Kirschbaum, A., Jobst, S., Wustmans, A., Kirschbaum, C., Rauh, W., & Hellhammer, D. (1997). Attenuated free cortisol response to psychosocial stress in children with atopic dermatitis. Psychosomatic Medicine, 59, 419-426.
16. Charlton, B. G., McGadey, J., Russell, D., & Neal, D. E. (1992). Noradrenergic innervation of the human adrenal cortex as revealed by dopamine-beta-hydroxylase immunohistochemistry. Journal of Anatomy, 180, 501-506.
17. Chida, Y., & Steptoe, A. (2009). Cortisol awakening response and psychosocial factors: A systematic review and meta-analysis. Biological Psychology, 80, 265-278.
18. Clow, A., & Hamer, M. (2010). The iceberg of social disadvantage and chronic stress: Implications for public health. Neuroscience and Biobehavioral Reviews, 35, 1-1.
19. Clow, A., Hucklebridge, F., Stalder, T., Evans, P., & Thorn, L. (2010). The cortisol awakening response: More than a measure of HPA axis function. Neuroscience and Biobehavioral Reviews, 35, 97-103.
20. Clow, A., Thorn, L., Evans, P., & Hucklebridge, F. (2004). The awakening cortisol response: Methodological issues and significance. Stress, 7, 29-37.
21. Cohen, S., Schwartz, J. E., Epel, E., Kirschbaum, C., Sidney, S., & Seeman, T. (2006). Socioeconomic status, race, and diurnal cortisol decline in the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Psychosomatic Medicine, 68, 41-50.
22. Crofford, L. J., Young, E. A., Engleberg, N. C., Korszun, A., Brucksch, C. B., McClure, L. A., ... Demitrack, M. A. (2004). Basal circadian and pulsatile ACTH and cortisol secretion in patients with fibromyalgia and/or chronic fatigue syndrome. Brain, Behavior, and Immunity, 18, 314-325.
23. von Dawans, B., Kirschbaum, C., & Heinrichs, M. (2011). The Trier Social Stress Test for Groups (TSST-G): A new research tool for controlled simultaneous social stress exposure in a group format. Psychoneuroendocrinology, 36, 514-522.
24. Demitrack, M. A., Dale, J. K., Straus, S. E., Laue, L., Listwak, S. J., Kruesi, M. J. P., ... Gold, P. W. (1991). Evidence for impaired activation of the hypothalamic-pituitary-adrenal axis in patients with chronic fatigue syndrome. Journal of Clinical Endocrinology and Metabolism, 73, 1224-1234.
25. DeSantis, A. S., Adam, E. K., Mendelsohn, K. A., & Doane, L. D. (2010). Concordance between self-reported and objective wakeup times in ambulatory salivary cortisol research. International Journal of Behavioral Medicine, 17, 74-78.
26. Dickerson, S. S., & Kemeny, M. E. (2004). Acute stressors and cortisol responses: A theoretical integration and synthesis of laboratory research. Psychological Bulletin, 130, 355-391.
27. Dockray, S., Bhattacharyya, M. R., Molloy, G. J., & Steptoe, A. (2008). The cortisol awakening response in relation to objective and subjective measures of waking in the morning. Psychoneuroendocrinology, 33, 77-82.
28. Edwards, S., Clow, A., Evans, P., & Hucklebridge, F. (2001). Exploration of the awakening cortisol response in relation to diurnal cortisol secretory activity. Life Sciences, 68, 2093-2103.
29. Edwards, S., Evans, P., Hucklebridge, F., & Clow, A. (2001). Association between time of awakening and diurnal cortisol secretory activity. Psychoneuroendocrinology, 26, 613-622.
30. Evans, P. D., Fredhoi, C., Loveday, C., Hucklebridge, F., Aitchison, E., Forte, D., & Clow, A. (2011). The diurnal cortisol cycle and cognitive performance in the healthy old. International Journal of Psychophysiology, 79, 371-377.
31. Foley, P., & Kirschbaum, C. (2010). Human hypothalamus-pituitary-adrenal axis responses to acute psychosocial stress in laboratory settings. Neuroscience and Biobehavioral Reviews, 35, 91-96.
32. Ford, M. B., & Collins, N. L. (2010). Self-esteem moderates neuroendocrine and psychological responses to interpersonal rejection. Journal of Personality and Social Psychology, 98, 405-419.
33. Fries, E., Dettenborn, L., & Kirschbaum, C. (2009). The cortisol awakening response (CAR): Facts and future directions. International Journal of Psychophysiology, 72, 67-73.
34. Fries, E., Hellhammer, D. H., & Hellhammer, J. (2006). Attenuation of the hypothalamic-pituitary-adrenal axis responsivity to the Trier Social Stress Test by the benzodiazepine alprazolam. Psychoneuroendocrinology, 31, 1278-1288.
35. Garde, A. H., Hansen, A. M., & Nikolajsen, T. B. (2003). An inter-laboratory comparison for determination of cortisol in saliva. Accreditation and Quality Assurance, 8, 16-20.
36. Genuth, S. M. (1998). The endocrine system. In R. M. Berne & M. N. Levy (Eds.), Psychophysiology (4th edn.), St. Louis, USA: Mosby.
37. Granger, D. A., Hibel, L. C., Fortunato, C. K., & Kapelewski, C. H. (2009). Medication effects on salivary cortisol: Tactics and strategy to minimize impact in behavioral and developmental science. Psychoneuroendocrinology, 34, 1437-1448.
38. Gunnar, M. R., Wewerka, S., Frenn, K., Long, J. D., & Griggs, C. (2009). Developmental changes in hypothalamus-pituitary-adrenal activity over the transition to adolescence: Normative changes and associations with puberty. Development and Psychopathology, 21, 69-85.
39. Haeusser, J. A., Kattenstroth, M., van Dick, R., & Mojzisch, A. (2012). "We" are not stressed: Social identity in groups buffers neuroendocrine stress reactions. Journal of Experimental Social Psychology, 48, 973-977.
40. Hellhammer, J., Fries, E., Schweisthal, O. W., Schlotz, W., Stone, A. A., & Hagemann, D. (2007). Several daily measurements are necessary to reliably assess the cortisol rise after awakening: State and trait components. Psychoneuroendocrinology, 32, 80-86.
41. Hicks, A. M., & Diamond, L. M. (2011). Don't go to bed angry: Attachment, conflict, and affective and physiological reactivity. Personal Relationships, 18, 266-284.
42. Holsboer, F. (2000). The corticosteroid receptor hypothesis of depression. Neuropsychopharmacology, 23, 477-501.
43. Huber, T. J., Issa, K., Schik, G., & Wolf, O. T. (2006). The cortisol awakening response is blunted in psychotherapy inpatients suffering from depression. Psychoneuroendocrinology, 31, 900-904.
44. Ice, G. H. (2005). Factors influencing cortisol level and slope among community dwelling older adults in Minnesota. Journal of Cross-Cultural Gerontology, 20, 91-108.
45. Jacobs, N, Nicolson, N. A., Derom, C., Delespaul, P., van Os, J., & Myin-Germeys, I. (2005). Electronic monitoring of salivary cortisol sampling compliance in daily life. Life Sciences, 76, 2431-2443.
46. Kirschbaum, C., & Hellhammer, D. H. (1989). Salivary cortisol in psychobiological research - An overview. Neuropsychobiology, 22, 150-169.
47. Kirschbaum, C., & Hellhammer, D. H. (1994). Salivary cortisol in psychoneuroendocrine research - Recent developments and applications. Psychoneuroendocrinology, 19, 313-333.
48. Kirschbaum, C., Wust, S., & Hellhammer, D. (1992). Consistent sex-differences in cortisol responses to psychological stress. Psychosomatic Medicine, 54, 648-657.
49. Kirschbaum, C., Wust, S., & Strasburger, C. J. (1992). Normal cigarette-smoking increases free cortisol in habitual smokers. Life Sciences, 50, 435-442.
50. Kirschbaum, C., Kudielka, B. M., Gaab, J., Schommer, N. C., & Hellhammer, D. H. (1999). Impact of gender, menstrual cycle phase, and oral contraceptives on the activity of the hypothalamus-pituitary- adrenal axis. Psychosomatic Medicine, 61, 154-162.
51. Kirschbaum, C., Pirke, K. M., & Hellhammer, D. H. (1993). The 'Trier Social Stress Test' - A tool for investigating psychobiological stress responses in a laboratory setting. Neuropsychobiology, 28, 76-81.
52. Kirschbaum, C., Pirke, K. M., & Hellhammer, D. H. (1995). Preliminary evidence for reduced cortisol responsivity to psychological stress in women using oral-contraceptive medication. Psychoneuroendocrinology, 20, 509-514.
53. Kirschbaum, C., Scherer, G., & Strasburger, C. J. (1994). Pituitary and adrenal hormone responses to pharmacological, physical, and psychological stimulation in habitual smokers and non-smokers. The Clinical Investigator, 72, 804-810.
54. Kirschbaum, C., Strasburger, C. J., & Langkrar, J. (1993). Attenuated cortisol response to psychological stress but not to CRH or ergometry in young habitual smokers. Pharmacology Biochemistry and Behavior, 44, 527-531.
55. Kudielka, B. M., & Kirschbaum, C. (2003). Awakening cortisol responses are influenced by health status and awakening time but not by menstrual cycle phase. Psychoneuroendocrinology, 28, 35-47.
56. Kudielka, B. M., Broderick, J. E., & Kirschbaum, C. (2003). Compliance with saliva sampling protocols: Electronic monitoring reveals invalid cortisol daytime profiles in noncompliant subjects. Psychosomatic Medicine, 65, 313-319.
57. Kudielka, B. M., Hellhammer, J., Hellhammer, D. H., Wolf, O. T., Pirke, K. M., Varadi, E., ... Kirschbaum, C. (1998). Sex differences in endocrine and psychological responses to psychosocial stress in healthy elderly subjects and the impact of a 2-week dehydroepiandrosterone treatment. Journal of Clinical Endocrinology and Metabolism, 83, 1756-1761.
58. Kudielka, B. M., Hellhammer, D. H., & Wust, S. (2009). Why do we respond so differently? Reviewing determinants of human salivary cortisol responses to challenge. Psychoneuroendocrinology, 34, 2-18.
59. Kudielka, B. M., Schmidt-Reinwald, A. K., Hellhammer, D. H., & Kirschbaum, C. (1999). Psychological and endocrine responses to psychosocial stress and dexamethasone/corticotropin-releasing hormone in healthy postmenopausal women and young controls: The impact of age and a two-week estradiol treatment. Neuroendocrinology, 70, 422-430.
60. Kudielka, B. M., Schommer, N. C., Hellhammer, D. H., & Kirschbaum, C. (2004). Acute HPA axis responses, heart rate, and mood changes to psychosocial stress (TSST) in humans at different times of day. Psychoneuroendocrinology, 29, 983-992.
61. Kumari, M., Badrick, E., Chandola, T., Adler, N. E., Epel, E., Seeman, T., ... Marmot, M. G. (2010). Measures of social position and cortisol secretion in an aging population: Findings from the Whitehall II study. Psychosomatic Medicine, 72, 27-34.
62. Kunz-Ebrecht, S. R., Kirschbaum, C., Marmot, M., & Steptoe, A. (2004). Differences in cortisol awakening response on work days and weekends in women and men from the Whitehall II cohort. Psychoneuroendocrinology, 29, 516-528.
63. Kyrou, I., & Tsigos, C. (2009). Stress hormones: Physiological stress and regulation of metabolism. Current Opinion in Pharmacology, 9, 787-793.
64. Lauderdale, D. S., Knutson, K. L., Yan, L. L., Rathouz, P. J., Hulley, S. B., Sidney, S., & Liu, K. (2006). Objectively measured sleep characteristics among early-middle-aged adults - The CARDIA study. American Journal of Epidemiology, 164, 5-16.
65. Lichstein, K. L., Stone, K. C., Donaldson, J., Nau, S. D., Soeffing, J. P., Murray, D., ... Aguillard, N. (2006). Actigraphy validation with insomnia. Sleep, 29, 232-239.
66. Liu, J. H., Kazer, R. R., & Rasmussen, D. D. (1987). Characterization of the 24-hour secretion patterns of adrenocorticotropin and cortisol in normal women and patients with Cushings-disease. Journal of Clinical Endocrinology and Metabolism, 64, 1027-1035.
67. Lovallo, W. R., Dickensheets, S. L., Myers, D. A., Thomas, T. L., & Nixon, S. J. (2000). Blunted stress cortisol response in abstinent alcoholic and polysubstance-abusing men. Alcoholism, Clinical and Experimental Research, 24, 651-658.
68. Lovallo, W. R., Whitsett, T. L., Al'Absi, M., Sung, B. H., Vincent, A. S., & Wilson, M. F. (2005). Caffeine stimulation of cortisol secretion across the waking hours in relation to caffeine intake levels. Psychosomatic Medicine, 67, 734-739.
69. Lupien, S. J., McEwen, B. S., Gunnar, M. R., & Heim, C. (2009). Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nature Reviews Neuroscience, 10, 434-445.
70. Makatsori, A., Duncko, R., Moncek, F., Loder, I., Katina, S., & Jezova, D. (2004). Modulation of neuroendocrine response and non-verbal behavior during psychosocial stress in healthy volunteers by the glutamate release-inhibiting drug lamotrigine. Neuroendocrinology, 79, 34-42.
71. McEwen, B. S. (2012). Brain on stress: How the social environment gets under the skin. Proceedings of the National Academy of Sciences of the United States of America, 109, 17180-17185.
72. McEwen, B. S. (2013). Hormones and the social brain. Science, 339, 279-280.
73. McRae, A. L., Saladin, M. E., Brady, K. T., Upadhyaya, H., Back, S. E., & Timmerman, M. A. (2006). Stress reactivity: Biological and subjective responses to the cold pressor and Trier Social stressors. Human Psychopharmacology: Clinical and Experimental, 21, 377-385.
74. Nicolson, N. A. (2004). Childhood parental loss and cortisol levels in adult men. Psychoneuroendocrinology, 29, 1012-1018.
75. Nicolson, N. A., Storms, C., Ponds, R., & Sulon, J. (1997). Salivary cortisol levels and stress reactivity in human aging. Journals of Gerontology Series A - Biological Sciences and Medical Sciences, 52, M68-M75.
76. Obel, C., Hedegaard, M., Henriksen, T. B., Secher, N. J., Olsen, J., & Levine, S. (2005). Stress and salivary cortisol during pregnancy. Psychoneuroendocrinology, 30, 647-656.
77. Okun, M. L., Krafty, R. T., Buysse, D. J., Monk, T. H., Reynolds III, C. F., Begley, A., & Hall, M. (2010). What constitutes too long of a delay? Determining the cortisol awakening response (CAR) using self-report and PSG-assessed wake time. Psychoneuroendocrinology, 35, 460-468.
78. Oskis, A., Loveday, C., Hucklebridge, F., Thorn, L., & Clow, A. (2009). Diurnal patterns of salivary cortisol across the adolescent period in healthy females. Psychoneuroendocrinology, 34, 307-316.
79. Pariante, C. M., Papadopoulos, A. S., Poon, L., Cleare, A. J., Checkley, S. A., English, J., ... Lightman, S. (2004). Four days of citalopram increase suppression of cortisol secretion by prednisolone in healthy volunteers. Psychopharmacology, 177, 200-206.
80. Pendry, P., & Adam, E. K. (2007). Associations between parents' marital functioning, maternal parenting quality, maternal emotion and child cortisol levels. International Journal of Behavioral Development, 31, 218-231.
81. Pruessner, J. C., Kirschbaum, C., & Hellhammer, D. (1995). Waking up - The first stressor of the day? Free cortisol levels double within minutes after awakening. Journal of Psychophysiology, 9, 365.
82. Pruessner, J. C., Wolf, O. T., Hellhammer, D. H., Buske-Kirschbaum, A., von Auer, K., Jobst, S., ... Kirschbaum, C. (1997). Free cortisol levels after awakening: A reliable biological marker for the assessment of adrenocortical activity. Life Sciences, 61, 2539-2549.
83. Rohleder, N., Kudielka, B. M., Hellhammer, D. H., Wolf, J. M., & Kirschbaum, C. (2002). Age and sex steroid-related changes in glucocorticoid sensitivity of pro-inflammatory cytokine production after psychosocial stress. Journal of Neuroimmunology, 126, 69-77.
84. Roy, M. P., Steptoe, A., & Kirschbaum, C. (1994). Association between smoking status and cardiovascular and cortisol stress responsivity in healthy young men. International Journal of Behavioral Medicine, 1, 264-283.
85. Scheer, F., & Buijs, R. M. (1999). Light affects morning salivary cortisol in humans. Journal of Clinical Endocrinology and Metabolism, 84, 3395-3398.
86. Schlotz, W., Hellhammer, J., Schulz, P., & Stone, A. A. (2004). Perceived work overload and chronic worrying predict weekend-weekday differences in the cortisol awakening response. Psychosomatic Medicine, 66, 207-214.
87. Sephton, S. E., Sapolsky, R. M., Kraemer, H. C., & Spiegel, D. (2000). Diurnal cortisol rhythm as a predictor of breast cancer survival. Journal of the National Cancer Institute, 92, 994-1000.
88. Smyth, N., Clow, A., Thorn, L., Hucklebridge, F., & Evans, P. (2013). Delays of 5-15min between awakening and the start of saliva sampling matter in assessment of the cortisol awakening response. Psychoneuroendocrinology, doi:10.1016/j.psyneuen.2012.12.013.
89. Stalder, T., Evans, P., Hucklebridge, F., & Clow, A. (2010). State associations with the cortisol awakening response in healthy females. Psychoneuroendocrinology, 35, 1245-1252.
90. Stalder, T., Hucklebridge, F., Evans, P., & Clow, A. (2009). Use of a single case study design to examine state variation in the cortisol awakening response: Relationship with time of awakening. Psychoneuroendocrinology, 34, 607-614.
91. Tassi, P., & Muzet, A. (2000). Sleep inertia. Sleep Medicine Reviews, 4, 341-353.
92. Thorn, L., Evans, P., Cannon, A., Hucklebridge, F., & Clow, A. (2011). Seasonal differences in the diurnal pattern of cortisol secretion in healthy participants and those with self-assessed seasonal affective disorder. Psychoneuroendocrinology, 36, 816-823.
93. Thorn, L., Hucklebridge, F., Esgate, A., Evans, P., & Clow, A. (2004). The effect of dawn simulation on the cortisol response to awakening in healthy participants. Psychoneuroendocrinology, 29, 925-930.
94. Turner-Cobb, J. M., Sephton, S. E., Koopman, C., Blake-Mortimer, J., & Spiegel, D. (2000). Social support and salivary cortisol in women with metastatic breast cancer. Psychosomatic Medicine, 62, 337-345.
95. Vining, R. F., McGinley, R. A., Maksvytis, J. J., & Ho, K. Y. (1983). Salivary cortisol - a better measure of adrenal-cortical function than serum cortisol. Annals of Clinical Biochemistry, 20, 329-335.
96. Weitzman, E. D., Fukushima, D., Nogeire, C., Roffwarg, H., Gallagher, T. F., & Hellman, L. (1971). Twenty-four hour pattern of the episodic secretion of cortisol in normal subjects. The Journal of Clinical Endocrinology, 33, 14-22.
97. Wilhelm, I., Born, J., Kudielka, B. M., Schlotz, W., & Wust, S. (2007). Is the cortisol awakening rise a response to awakening? Psychoneuroendocrinology, 32, 358-366.
98. Williams, E., Magid, K., & Steptoe, A. (2005). The impact of time of waking and concurrent subjective stress on the cortisol response to awakening. Psychoneuroendocrinology, 30, 139-148.
99. Windle, R. J., Wood, S. A., Lightman, S. L., & Ingram, C. D. (1998). The pulsatile characteristics of hypothalamo-pituitary-adrenal activity in female Lewis and Fischer 344 rats and its relationship to differential stress responses. Endocrinology, 139, 4044-4052.
100. Wolf, O. T., Schommer, N. C., Hellhammer, D. H., McEwen, B. S., & Kirschbaum, C. (2001). The relationship between stress induced cortisol levels and memory differs between men and women. Psychoneuroendocrinology, 26, 711-720.
101. Wolfram, M., Bellingrath, S., & Kudielka, B. M. (2011). The cortisol awakening response (CAR) across the female menstrual cycle. Psychoneuroendocrinology, 36, 905-912.
102. Wright, C. E., & Steptoe, A. (2005). Subjective socioeconomic position, gender and cortisol responses to waking in an elderly population. Psychoneuroendocrinology, 30, 582-590.
103. Wuest, S., Wolf, J., Hellhammer, D. H., Federenko, I. S., Schommer, N., & Kirschbaum, C. (2000). The cortisol response to awakening - Normal values and confounds. Noise & Health, 7, 77-85.
104. Wust, S., Wolf, J., Hellhammer, D. H., Federenko, I., Schommer, N., & Kirschbaum, C. (2000). The cortisol awakening response - Normal values and confounds. Noise & Health, 2, 79-88.