Role of slit and robo proteins in the development of dopaminergic neurons

Developmental Neuroscience

Volumn 35, Issue 4, 2013, Pages 285-292

  Cornide Petronio, María Eugenia ^a   Barreiro Iglesias, Antón ^b  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Dopamine; Parkinson's disease; Restless legs syndrome; Schizophrenia; Spinal cord; Zebrafish

Indexed keywords

DOPAMINE; ROUNDABOUT RECEPTOR; SLIT PROTEIN;

BRAIN REGION; DOPAMINERGIC NERVE CELL; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LONGITUDINAL STUDY; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NEURITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION; SPINAL GANGLION; ZEBRA FISH;

ANIMALS; BRAIN; DOPAMINERGIC NEURONS; FEMALE; GLYCOPROTEINS; MICE; MUTATION; NERVE TISSUE PROTEINS; NEURAL PATHWAYS; PREGNANCY; PRIMARY CELL CULTURE; RATS; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION; ZEBRAFISH;

EID: 84883384454     PISSN: 03785866     EISSN: 14219859     Source Type: Journal    
DOI: 10.1159/000351023     Document Type: Review

References (30)

1. Savitt JM, Dawson VL, Dawson TM: Diagnosis and treatment of Parkinson disease: Molecules to medicine. J Clin Invest 2006; 116: 1744-1754.
2. Sesack SR, Carr DB: Selective prefrontal cortex inputs to dopamine cells: Implications for schizophrenia. Physiol Behav 2002; 77: 513-517.
3. Barraud Q, Obeid I, Aubert I, Barriere G, Contamin H, McGuire S, Ravenscroft P, Porras G, Tison F, Bezard E, Ghorayeb I: Neuroanatomical study of the A11 diencephalospinal pathway in the non-human primate. PLoS One 2010; 5:e13306.
4. Seeger M, Tear G, Ferres-Marco D, Goodman CS: Mutations affecting growth cone guidance in Drosophila : Genes necessary for guidance toward or away from the midline. Neuron 1993; 10: 409-426.
5. Rothberg JM, Jacobs JR, Goodman CS, Artavanis-Tsakonas S: Slit: An extracellular protein necessary for development of midline glia and commissural axon pathways contains both EGF and LRR domains. Genes Dev 1990; 4: 2169-2187.
6. Chedotal A: Slits and their receptors. Adv Exp Med Biol 2007; 621: 65-80.
7. Hutson LD, Jurynec MJ, Yeo SY, Okamoto H, Chien CB: Two divergent slit1 genes in zebrafish. Dev Dyn 2003; 228: 358-369.
8. Ypsilanti AR, Zagar Y, Chedotal A: Moving away from the midline: New developments for Slit and Robo. Development 2010; 137: 1939-1952.
9. Slovakova J, Speicher S, Sanchez-Soriano N, Prokop A, Carmena A: The actin-binding protein Canoe/AF-6 forms a complex with Robo and is required for Slit-Robo signaling during axon pathfinding at the CNS midline. J Neurosci 2012; 32: 10035-10044.
10. Bagri A, Marin O, Plump AS, Mak J, Pleasure SJ, Rubenstein JL, Tessier-Lavigne M: Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain. Neuron 2002; 33: 233-248.
11. Lin L, Rao Y, Isacson O: Netrin-1 and Slit-2 regulate and direct neurite growth of ventral midbrain dopaminergic neurons. Mol Cell Neurosci 2005; 28: 547-555.
12. Lin L, Isacson O: Axonal growth regulation of fetal and embryonic stem cell-derived dopaminergic neurons by Netrin-1 and Slits. Stem Cells 2006; 24: 2504-2513.
13. Kastenhuber E, Kern U, Bonkowsky JL, Chien CB, Driever W, Schweitzer J: Netrin-DCC, Robo-Slit, and heparan sulfate proteoglycans coordinate lateral positioning of longitudinal dopaminergic diencephalospinal axons. J Neurosci 2009; 29: 8914-8926.
14. Cord BJ, Li J, Works M, McConnell SK, Palmer T, Hynes MA: Characterization of axon guidance cue sensitivity of human embryonic stem cell-derived dopaminergic neurons. Mol Cell Neurosci 2010; 45: 324-334.
15. Dugan JP, Stratton A, Riley HP, Farmer WT, Mastick GS: Midbrain dopaminergic axons are guided longitudinally through the diencephalon by Slit/Robo signals. Mol Cell Neurosci 2011; 46: 347-356.
16. Schweitzer J, Lohr H, Bonkowsky JL, Hubscher K, Driever W: Sim1a and Arnt2 contribute to hypothalamo-spinal axon guidance by regulating Robo2 activity via a Robo3-dependent mechanism. Development 2013; 140: 93-106.
17. Wyatt C, Ebert A, Reimer MM, Rasband K, Hardy M, Chien CB, Becker T, Becker CG: Analysis of the astray/robo2 zebrafish mutant reveals that degenerating tracts do not provide strong guidance cues for regenerating optic axons. J Neurosci 2010; 30: 13838-13849.
18. Karlstrom RO, Trowe T, Klostermann S, Baier H, Brand M, Crawford AD, Grunewald B, Haffter P, Hoffmann H, Meyer SU, Muller BK, Richter S, Van Eeden FJ, Nusslein-Volhard C, Bonhoeffer F: Zebrafish mutations affecting retinotectal axon pathfinding. Development 1996; 123: 427-438.
19. Kim M, Roesener AP, Mendonca PR, Mastick GS: Robo1 and Robo2 have distinct roles in pioneer longitudinal axon guidance. Dev Biol 2011; 358: 181-188.
20. Tay TL, Ronneberger O, Ryu S, Nitschke R, Driever W: Comprehensive catecholaminergic projectome analysis reveals single-neuron integration of zebrafish ascending and descending dopaminergic systems. Nat Commun 2011; 2: 171.
21. Kaslin J, Panula P: Comparative anatomy of the histaminergic and other aminergic systems in zebrafish ( Danio rerio ). J Comp Neurol 2001; 440: 342-377.
22. Qu S, Le W, Zhang X, Xie W, Zhang A, Ondo WG: Locomotion is increased in A11-lesioned mice with iron deprivation: A possible animal model for restless legs syndrome. J Neuropathol Exp Neurol 2007; 66: 383-388.
23. Clemens S, Rye D, Hochman S: Restless legs syndrome: Revisiting the dopamine hypothesis from the spinal cord perspective. Neurology 2006; 67: 125-130.
24. Jordan LM, Liu J, Hedlund PB, Akay T, Pearson KG: Descending command systems for the initiation of locomotion in mammals. Brain Res Rev 2008; 57: 183-91.
25. Lindvall O: Developing dopaminergic cell therapy for Parkinson's disease-give up or move forward? Mov Disord 2013; 28: 268-273.
26. Wehrle R, Camand E, Chedotal A, Sotelo C, Dusart I: Expression of netrin-1, slit-1 and slit-but not of slit-2 after cerebellar and spinal cord lesions. Eur J Neurosci 2005; 22: 2134-2144.
27. Lu YJ, Xu NW, Yang WQ: Immunofluorescence laser confocal expression and localization study of rat nerve growth guidance cues Netrin-1 and Slit2 after spinal cord injury. Chin J Traumatol 2008; 11: 98-103.
28. Liu JB, Jiang YQ, Gong AH, Zhang ZJ, Jiang Q, Chu XP: Expression of Slit2 and Robo1 after traumatic lesions of the rat spinal cord. Acta Histochem 2011; 113: 43-48.
29. Kuscha V, Barreiro-Iglesias A, Becker CG, Becker T: Plasticity of tyrosine hydroxylase and serotonergic systems in the regenerating spinal cord of adult zebrafish. J Comp Neurol 2012; 520: 933-951.
30. Albanese A, Altavista MC, Rossi P: Organization of central nervous system dopaminergic pathways. J Neural Transm Suppl 1986; 22: 3-17.