메뉴 건너뛰기




Volumn 191, Issue 5, 2013, Pages 2144-2154

Paradoxical effect of cortistatin treatment and its deficiency on experimental autoimmune encephalomyelitis

Author keywords

[No Author keywords available]

Indexed keywords

CORTISTATIN; GLUCOCORTICOID;

EID: 84883369505     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1300384     Document Type: Article
Times cited : (34)

References (43)
  • 1
    • 0029939467 scopus 로고    scopus 로고
    • Multiple sclerosis: A coordinated immunological attack against myelin in the central nervous system
    • Steinman, L. 1996. Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system. Cell 85: 299-302.
    • (1996) Cell , vol.85 , pp. 299-302
    • Steinman, L.1
  • 2
    • 0033231305 scopus 로고    scopus 로고
    • Assessment of animal models for MS and demyelinating disease in the design of rational therapy
    • Steinman, L. 1999. Assessment of animal models for MS and demyelinating disease in the design of rational therapy. Neuron 24: 511-514.
    • (1999) Neuron , vol.24 , pp. 511-514
    • Steinman, L.1
  • 3
    • 0038459185 scopus 로고    scopus 로고
    • The enigma of multiple sclerosis: Inflammation and neurodegeneration cause heterogeneous dysfunction and damage
    • Owens, T. 2003. The enigma of multiple sclerosis: inflammation and neurodegeneration cause heterogeneous dysfunction and damage. Curr. Opin. Neurol. 16: 259-265.
    • (2003) Curr. Opin. Neurol. , vol.16 , pp. 259-265
    • Owens, T.1
  • 7
    • 0033818629 scopus 로고    scopus 로고
    • Cortistatin: A member of the somatostatin neuropeptide family with distinct physiological functions
    • Spier, A. D., and L. de Lecea. 2000. Cortistatin: a member of the somatostatin neuropeptide family with distinct physiological functions. Brain Res. Brain Res. Rev. 33: 228-241.
    • (2000) Brain Res. Brain Res. Rev. , vol.33 , pp. 228-241
    • Spier, A.D.1    De Lecea, L.2
  • 8
    • 33645080443 scopus 로고    scopus 로고
    • Cortistatin, a new antiinflammatory peptide with therapeutic effect on lethal endotoxemia
    • Gonzalez-Rey, E., A. Chorny, G. Robledo, and M. Delgado. 2006. Cortistatin, a new antiinflammatory peptide with therapeutic effect on lethal endotoxemia. J. Exp. Med. 203: 563-571.
    • (2006) J. Exp. Med. , vol.203 , pp. 563-571
    • Gonzalez-Rey, E.1    Chorny, A.2    Robledo, G.3    Delgado, M.4
  • 10
    • 34047199656 scopus 로고    scopus 로고
    • Therapeutic effect of cortistatin on experimental arthritis by downregulating inflammatory and Th1 responses
    • Gonzalez-Rey, E., A. Chorny, R. G. Del Moral, N. Varela, and M. Delgado. 2007. Therapeutic effect of cortistatin on experimental arthritis by downregulating inflammatory and Th1 responses. Ann. Rheum. Dis. 66: 582-588.
    • (2007) Ann. Rheum. Dis. , vol.66 , pp. 582-588
    • Gonzalez-Rey, E.1    Chorny, A.2    Del Moral, R.G.3    Varela, N.4    Delgado, M.5
  • 13
    • 0006278393 scopus 로고
    • A method for the combined staining of cells and fibers in the nervous system
    • Kluver, H., and E. Barrera. 1953. A method for the combined staining of cells and fibers in the nervous system. J. Neuropathol. Exp. Neurol. 12: 400-403.
    • (1953) J. Neuropathol. Exp. Neurol. , vol.12 , pp. 400-403
    • Kluver, H.1    Barrera, E.2
  • 14
    • 84880113614 scopus 로고    scopus 로고
    • An easy and fast way to obtain a high number of glial cells from rat cerebral tissue: A beginners approach
    • doi: 10.1038/protex. 2011.2188
    • Mecha, M., P. M. Iñigo, L. Mestre, M. Hernangómez, J. Borrell, and C. Guaza. 2011. An easy and fast way to obtain a high number of glial cells from rat cerebral tissue: A beginners approach. Protocol Exchange. doi: 10.1038/protex. 2011.2188
    • (2011) Protocol Exchange
    • Mecha, M.1    Iñigo, P.M.2    Mestre, L.3    Hernangómez, M.4    Borrell, J.5    Guaza, C.6
  • 16
    • 0034127008 scopus 로고    scopus 로고
    • Mice deficient for corticotropinreleasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress
    • Bale, T. L., A. Contarino, G. W. Smith, R. Chan, L. H. Gold, P. E. Sawchenko, G. F. Koob, W. W. Vale, and K. F. Lee. 2000. Mice deficient for corticotropinreleasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress. Nat. Genet. 24: 410-414.
    • (2000) Nat. Genet. , vol.24 , pp. 410-414
    • Bale, T.L.1    Contarino, A.2    Smith, G.W.3    Chan, R.4    Gold, L.H.5    Sawchenko, P.E.6    Koob, G.F.7    Vale, W.W.8    Lee, K.F.9
  • 17
    • 0021889262 scopus 로고
    • Identification of cell surface carbohydrate and antigenic changes between noninfective and infective developmental stages of Leishmania major promastigotes
    • Sacks, D. L., S. Hieny, and A. Sher. 1985. Identification of cell surface carbohydrate and antigenic changes between noninfective and infective developmental stages of Leishmania major promastigotes. J. Immunol. 135: 564-569.
    • (1985) J. Immunol. , vol.135 , pp. 564-569
    • Sacks, D.L.1    Hieny, S.2    Sher, A.3
  • 18
    • 0034533054 scopus 로고    scopus 로고
    • Leishmania major-infected murine langerhans cell-like dendritic cells from susceptible mice release IL-12 after infection and vaccinate against experimental cutaneous Leishmaniasis
    • von Stebut, E., Y. Belkaid, B. V. Nguyen, M. Cushing, D. L. Sacks, and M. C. Udey. 2000. Leishmania major-infected murine langerhans cell-like dendritic cells from susceptible mice release IL-12 after infection and vaccinate against experimental cutaneous Leishmaniasis. Eur. J. Immunol. 30: 3498-3506.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 3498-3506
    • Von Stebut, E.1    Belkaid, Y.2    Nguyen, B.V.3    Cushing, M.4    Sacks, D.L.5    Udey, M.C.6
  • 19
    • 35549010987 scopus 로고    scopus 로고
    • The origin and application of experimental autoimmune encephalomyelitis
    • Baxter, A. G. 2007. The origin and application of experimental autoimmune encephalomyelitis. Nat. Rev. Immunol. 7: 904-912.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 904-912
    • Baxter, A.G.1
  • 20
    • 73349109145 scopus 로고    scopus 로고
    • Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes
    • Jäger, A., V. Dardalhon, R. A. Sobel, E. Bettelli, and V. K. Kuchroo. 2009. Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes. J. Immunol. 183: 7169-7177.
    • (2009) J. Immunol. , vol.183 , pp. 7169-7177
    • Jäger, A.1    Dardalhon, V.2    Sobel, R.A.3    Bettelli, E.4    Kuchroo, V.K.5
  • 21
    • 79956116032 scopus 로고    scopus 로고
    • RORgt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation
    • Codarri, L. G., G. Gyülvészi, V. Tosevski, L. Hesske, A. Fontana, L. Magnenat, T. Suter, and B. Becher. 2011. RORgt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation. Nat. Immunol. 12: 560-567.
    • (2011) Nat. Immunol. , vol.12 , pp. 560-567
    • Codarri, L.G.1    Gyülvészi, G.2    Tosevski, V.3    Hesske, L.4    Fontana, A.5    Magnenat, L.6    Suter, T.7    Becher, B.8
  • 22
    • 0036838536 scopus 로고    scopus 로고
    • Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis
    • Kohm, A. P., P. A. Carpentier, H. A. Anger, and S. D. Miller. 2002. Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis. J. Immunol. 169: 4712-4716.
    • (2002) J. Immunol. , vol.169 , pp. 4712-4716
    • Kohm, A.P.1    Carpentier, P.A.2    Anger, H.A.3    Miller, S.D.4
  • 23
    • 0141678964 scopus 로고    scopus 로고
    • Epicutaneous immunization with autoantigenic peptides induces T suppressor cells that prevent experimental allergic encephalomyelitis
    • Bynoe, M. S., J. T. Evans, C. Viret, and C. A. Janeway, Jr. 2003. Epicutaneous immunization with autoantigenic peptides induces T suppressor cells that prevent experimental allergic encephalomyelitis. Immunity 19: 317-328.
    • (2003) Immunity , vol.19 , pp. 317-328
    • Bynoe, M.S.1    Evans, J.T.2    Viret, C.3    Janeway Jr., C.A.4
  • 24
    • 77957062260 scopus 로고    scopus 로고
    • Functional role of brain-derived neurotrophic factor in neuroprotective autoimmunity: Therapeutic implications in a model of multiple sclerosis
    • Linker, R. A., D. H. Lee, S. Demir, S. Wiese, N. Kruse, I. Siglienti, E. Gerhardt, H. Neumann, M. Sendtner, F. Lühder, and R. Gold. 2010. Functional role of brain-derived neurotrophic factor in neuroprotective autoimmunity: therapeutic implications in a model of multiple sclerosis. Brain 133: 2248-2263.
    • (2010) Brain , vol.133 , pp. 2248-2263
    • Linker, R.A.1    Lee, D.H.2    Demir, S.3    Wiese, S.4    Kruse, N.5    Siglienti, I.6    Gerhardt, E.7    Neumann, H.8    Sendtner, M.9    Lühder, F.10    Gold, R.11
  • 25
    • 0029892470 scopus 로고    scopus 로고
    • Physiology of the neurotrophins
    • Lewin, G. R., and Y. A. Barde. 1996. Physiology of the neurotrophins. Annu. Rev. Neurosci. 19: 289-317.
    • (1996) Annu. Rev. Neurosci. , vol.19 , pp. 289-317
    • Lewin, G.R.1    Barde, Y.A.2
  • 27
    • 33645284772 scopus 로고    scopus 로고
    • Neural regulation of innate immunity: A coordinated nonspecific host response to pathogens
    • Sternberg, E. M. 2006. Neural regulation of innate immunity: a coordinated nonspecific host response to pathogens. Nat. Rev. Immunol. 6: 318-328.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 318-328
    • Sternberg, E.M.1
  • 30
    • 73349110962 scopus 로고    scopus 로고
    • Control of allograft rejection in mice by applying a novel neuropeptide, cortistatin
    • Wang, J., R. Zhao, F. Zhang, J. Li, B. Huo, Y. Cao, and K. Dou. 2008. Control of allograft rejection in mice by applying a novel neuropeptide, cortistatin. Adv. Ther. 25: 1331-1341.
    • (2008) Adv. Ther. , vol.25 , pp. 1331-1341
    • Wang, J.1    Zhao, R.2    Zhang, F.3    Li, J.4    Huo, B.5    Cao, Y.6    Dou, K.7
  • 31
    • 33845900208 scopus 로고    scopus 로고
    • Regulation of immune tolerance by anti-inflammatory neuropeptides
    • Gonzalez-Rey, E., A. Chorny, and M. Delgado. 2007. Regulation of immune tolerance by anti-inflammatory neuropeptides. Nat. Rev. Immunol. 7: 52-63.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 52-63
    • Gonzalez-Rey, E.1    Chorny, A.2    Delgado, M.3
  • 32
    • 0038617545 scopus 로고    scopus 로고
    • The complex role of interleukin-10 in autoimmunity
    • Groux, H., and F. Cottrez. 2003. The complex role of interleukin-10 in autoimmunity. J. Autoimmun. 20: 281-285.
    • (2003) J. Autoimmun. , vol.20 , pp. 281-285
    • Groux, H.1    Cottrez, F.2
  • 33
    • 50249171613 scopus 로고    scopus 로고
    • Lowered cortistatin expression is an early event in the human diabetic retina and is associated with apoptosis and glial activation
    • Carrasco, E., C. Hernández, I. de Torres, J. Farrés, and R. Simó. 2008. Lowered cortistatin expression is an early event in the human diabetic retina and is associated with apoptosis and glial activation. Mol. Vis. 14: 1496-1502.
    • (2008) Mol. Vis. , vol.14 , pp. 1496-1502
    • Carrasco, E.1    Hernández, C.2    De Torres, I.3    Farrés, J.4    Simó., R.5
  • 34
    • 78650588402 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide loss leads to impaired CNS parenchymal T-cell infiltration and resistance to experimental autoimmune encephalomyelitis
    • Abad, C., Y. V. Tan, R. Lopez, H. Nobuta, H. Dong, P. Phan, J. M. Feng, A. T. Campagnoni, and J. A. Waschek. 2010. Vasoactive intestinal peptide loss leads to impaired CNS parenchymal T-cell infiltration and resistance to experimental autoimmune encephalomyelitis. Proc. Natl. Acad. Sci. USA 107: 19555-19560.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 19555-19560
    • Abad, C.1    Tan, Y.V.2    Lopez, R.3    Nobuta, H.4    Dong, H.5    Phan, P.6    Feng, J.M.7    Campagnoni, A.T.8    Waschek, J.A.9
  • 35
    • 35549010235 scopus 로고    scopus 로고
    • The activation of somatostatinergic receptors by either somatostatin-14 or cortistatin-17 often inhibits ACTH hypersecretion in patients with Cushing's disease
    • Giordano, R., A. Picu, L. Bonelli, F. Broglio, F. Prodam, S. Grottoli, G. Muccioli, E. Ghigo, and E. Arvat. 2007. The activation of somatostatinergic receptors by either somatostatin-14 or cortistatin-17 often inhibits ACTH hypersecretion in patients with Cushing's disease. Eur. J. Endocrinol. 157: 393-398.
    • (2007) Eur. J. Endocrinol. , vol.157 , pp. 393-398
    • Giordano, R.1    Picu, A.2    Bonelli, L.3    Broglio, F.4    Prodam, F.5    Grottoli, S.6    Muccioli, G.7    Ghigo, E.8    Arvat, E.9
  • 36
    • 84859419532 scopus 로고    scopus 로고
    • Cortistatin modulates the expression and release of corticotrophin releasing hormone in rat brain. Comparison with somatostatin and octreotide
    • Tringali, G., M. C. Greco, L. Lisi, G. Pozzoli, and P. Navarra. 2012. Cortistatin modulates the expression and release of corticotrophin releasing hormone in rat brain. Comparison with somatostatin and octreotide. Peptides 34: 353-359.
    • (2012) Peptides , vol.34 , pp. 353-359
    • Tringali, G.1    Greco, M.C.2    Lisi, L.3    Pozzoli, G.4    Navarra, P.5
  • 37
    • 84870038215 scopus 로고    scopus 로고
    • The vagus nerve and the inflammatory reflex - Linking immunity and metabolism
    • Pavlov, V. A., and K. J. Tracey. 2012. The vagus nerve and the inflammatory reflex - linking immunity and metabolism. Nat. Rev. Endocrinol. 8: 743-754.
    • (2012) Nat. Rev. Endocrinol. , vol.8 , pp. 743-754
    • Pavlov, V.A.1    Tracey, K.J.2
  • 38
    • 63149164387 scopus 로고    scopus 로고
    • Nicotinic attenuation of central nervous system inflammation and autoimmunity
    • Shi, F. D., W. H. Piao, Y. P. Kuo, D. I. Campagnolo, T. L. Vollmer, and R. J. Lukas. 2009. Nicotinic attenuation of central nervous system inflammation and autoimmunity. J. Immunol. 182: 1730-1739.
    • (2009) J. Immunol. , vol.182 , pp. 1730-1739
    • Shi, F.D.1    Piao, W.H.2    Kuo, Y.P.3    Campagnolo, D.I.4    Vollmer, T.L.5    Lukas, R.J.6
  • 40
    • 0022393232 scopus 로고
    • Prazosin, an alpha 1-adrenergic receptor antagonist, suppresses experimental autoimmune encephalomyelitis in the Lewis rat
    • Brosnan, C. F., E. A. Goldmuntz, W. Cammer, S. M. Factor, B. R. Bloom, and W. T. Norton. 1985. Prazosin, an alpha 1-adrenergic receptor antagonist, suppresses experimental autoimmune encephalomyelitis in the Lewis rat. Proc. Natl. Acad. Sci. USA 82: 5915-5919.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 5915-5919
    • Brosnan, C.F.1    Goldmuntz, E.A.2    Cammer, W.3    Factor, S.M.4    Bloom, B.R.5    Norton, W.T.6
  • 41
    • 84876837147 scopus 로고    scopus 로고
    • Therapeutic effect of ghrelin in experimental autoimmune encephalomyelitis by inhibiting antigen-specific Th1/Th17 responses and inducing regulatory T cells
    • Souza-Moreira, L., V. Delgado-Maroto, M. Morell, F. O'Valle, R. G. Del Moral, and E. Gonzalez-Rey. 2013. Therapeutic effect of ghrelin in experimental autoimmune encephalomyelitis by inhibiting antigen-specific Th1/Th17 responses and inducing regulatory T cells. Brain Behav. Immun. 30: 54-60.
    • (2013) Brain Behav. Immun. , vol.30 , pp. 54-60
    • Souza-Moreira, L.1    Delgado-Maroto, V.2    Morell, M.3    O'Valle, F.4    Del Moral, R.G.5    Gonzalez-Rey, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.